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Gene: Ticam2 (toll-like receptor adaptor molecule 2) Mus musculus
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Symbol: Ticam2
Name: toll-like receptor adaptor molecule 2
Description: Exhibits phospholipid binding activity. Involved in several processes, including positive regulation of cytokine production; positive regulation of interleukin-18-mediated signaling pathway; and response to interleukin-12. Localizes to endosome and plasma membrane. Is expressed in testis and ureter. Orthologous to several human genes including TMED7-TICAM2 (TMED7-TICAM2 readthrough); PARTICIPATES IN interleukin-1 signaling pathway; Toll-like receptor signaling pathway; INTERACTS WITH chloroquine; ciguatoxin CTX1B; lipopolysaccharide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: B430113A10; MGC107370; TICAM-2; TIR domain-containing adapter molecule 2; TIR domain-containing adapter protein; Tirp; Toll-interleukin I receptor domain (TIR)-containing adaptor molecule (TICAM) 2; toll/interleukin-1 receptor domain-containing protein; TRAM; Trif; TRIF-related adapter molecule TRAM; TRIF-related adaptor molecule
Orthologs:
Homo sapiens (human) : TICAM2 (toll like receptor adaptor molecule 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ticam2 (toll-like receptor adaptor molecule 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ticam2 (toll like receptor adaptor molecule 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TICAM2 (toll like receptor adaptor molecule 2)
Canis lupus familiaris (dog) : TICAM2 (toll like receptor adaptor molecule 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ticam2 (toll like receptor adaptor molecule 2)
Sus scrofa (pig) : TICAM2 (toll like receptor adaptor molecule 2)
Chlorocebus sabaeus (African green monkey) : TICAM2 (toll like receptor adaptor molecule 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1846,557,291 - 46,574,533 (-)EnsemblGRCm38mm10GRCm38
GRCm381846,558,231 - 46,574,533 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371846,717,885 - 46,734,187 (-)NCBIGRCm37mm9NCBIm37
MGSCv361846,683,562 - 46,699,863 (-)NCBImm8
Celera1847,917,939 - 47,934,160 (-)NCBICelera
Cytogenetic Map18CNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ticam2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1550939
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.