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Gene: Spint1 (serine protease inhibitor, Kunitz type 1) Mus musculus
Symbol: Spint1
Name: serine protease inhibitor, Kunitz type 1
Description: Predicted to have serine-type endopeptidase inhibitor activity. Involved in extracellular matrix organization; neural tube closure; and placenta development. Localizes to the plasma membrane. Is expressed in several structures, including alimentary system; brain; extraembryonic component; genitourinary system; and sensory organ. Orthologous to human SPINT1 (serine peptidase inhibitor, Kunitz type 1); INTERACTS WITH 17beta-estradiol; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: HAI-1; hepatocyte growth factor activator inhibitor type 1; kunitz-type protease inhibitor 1
Homo sapiens (human) : SPINT1 (serine peptidase inhibitor, Kunitz type 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Spint1 (serine peptidase inhibitor, Kunitz type 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Spint1 (serine peptidase inhibitor, Kunitz type 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SPINT1 (serine peptidase inhibitor, Kunitz type 1)
Canis lupus familiaris (dog) : SPINT1 (serine peptidase inhibitor, Kunitz type 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Spint1 (serine peptidase inhibitor, Kunitz type 1)
Sus scrofa (pig) : SPINT1 (serine peptidase inhibitor, Kunitz type 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl2119,237,362 - 119,249,527 (+)Ensembl
GRCm382119,237,360 - 119,249,535 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372119,063,096 - 119,075,250 (+)NCBIGRCm37mm9NCBIm37
MGSCv362118,928,918 - 118,940,633 (+)NCBImm8
Celera2120,387,921 - 120,400,196 (+)NCBICelera
Cytogenetic Map2 E5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Spint1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1550885
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.