Rer1 (retention in endoplasmic reticulum sorting receptor 1) - Rat Genome Database

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Gene: Rer1 (retention in endoplasmic reticulum sorting receptor 1) Mus musculus
Analyze
Symbol: Rer1
Name: retention in endoplasmic reticulum sorting receptor 1
RGD ID: 1550846
MGI Page MGI
Description: Exhibits acetylcholine receptor binding activity. Involved in positive regulation of protein localization to plasma membrane and skeletal muscle acetylcholine-gated channel clustering. Localizes to cell surface and endoplasmic reticulum-Golgi intermediate compartment. Is expressed in brain; intestine; liver; muscle tissue; and spleen. Orthologous to human RER1 (retention in endoplasmic reticulum sorting receptor 1); INTERACTS WITH 1,2-dimethylhydrazine; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110060F11Rik; 5830454N22Rik; AU043380; RER1 retention in endoplasmic reticulum 1 homolog
RGD Orthologs
Human
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394155,158,566 - 155,170,840 (-)NCBIGRCm39mm39
GRCm39 Ensembl4155,158,567 - 155,170,839 (-)Ensembl
GRCm384155,074,109 - 155,086,371 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4155,074,110 - 155,086,382 (-)EnsemblGRCm38mm10GRCm38
MGSCv374154,448,221 - 154,460,406 (-)NCBIGRCm37mm9NCBIm37
MGSCv364153,917,912 - 153,930,097 (-)NCBImm8
Celera4157,346,554 - 157,358,733 (-)NCBICelera
Cytogenetic Map4E2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12520002   PMID:12904583   PMID:14610273   PMID:15489334   PMID:15782199   PMID:16141072  
PMID:16141073   PMID:17967808   PMID:18799693   PMID:20956802   PMID:21187406   PMID:21873635   PMID:23129766   PMID:23479743   PMID:24194600   PMID:25737280   PMID:28117367   PMID:28378742  
PMID:30196744   PMID:30260951   PMID:30550785  


Genomics

Comparative Map Data
Rer1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394155,158,566 - 155,170,840 (-)NCBIGRCm39mm39
GRCm39 Ensembl4155,158,567 - 155,170,839 (-)Ensembl
GRCm384155,074,109 - 155,086,371 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4155,074,110 - 155,086,382 (-)EnsemblGRCm38mm10GRCm38
MGSCv374154,448,221 - 154,460,406 (-)NCBIGRCm37mm9NCBIm37
MGSCv364153,917,912 - 153,930,097 (-)NCBImm8
Celera4157,346,554 - 157,358,733 (-)NCBICelera
Cytogenetic Map4E2NCBI
RER1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl12,391,775 - 2,405,442 (+)EnsemblGRCh38hg38GRCh38
GRCh3812,391,841 - 2,405,436 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712,323,280 - 2,336,875 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612,313,074 - 2,326,734 (+)NCBINCBI36hg18NCBI36
Build 3412,355,490 - 2,367,350NCBI
Celera1249,823 - 263,535 (-)NCBI
Cytogenetic Map1p36.32NCBI
HuRef11,601,775 - 1,615,592 (+)NCBIHuRef
CHM1_112,310,240 - 2,323,952 (+)NCBICHM1_1
Rer1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25165,634,567 - 165,646,643 (-)NCBI
Rnor_6.0 Ensembl5172,476,747 - 172,488,822 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.05172,476,746 - 172,488,822 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05175,932,625 - 175,944,701 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45171,875,696 - 171,887,772 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15171,885,922 - 171,898,345 (-)NCBI
Celera5163,840,333 - 163,852,410 (-)NCBICelera
Cytogenetic Map5q36NCBI
Rer1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554868,791,457 - 8,802,691 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554868,791,457 - 8,802,691 (-)NCBIChiLan1.0ChiLan1.0
RER1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1557,278,349 - 57,288,564 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl557,278,371 - 57,285,870 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha557,354,837 - 57,365,141 (+)NCBI
ROS_Cfam_1.0557,480,563 - 57,490,874 (+)NCBI
UMICH_Zoey_3.1557,471,831 - 57,482,138 (+)NCBI
UNSW_CanFamBas_1.0557,364,184 - 57,374,471 (+)NCBI
UU_Cfam_GSD_1.0557,753,820 - 57,764,123 (+)NCBI
Rer1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505828,302,503 - 28,313,100 (+)NCBI
SpeTri2.0NW_0049367371,152,937 - 1,164,817 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RER1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl664,301,199 - 64,311,784 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1664,301,139 - 64,311,526 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2658,710,593 - 58,721,038 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RER1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120129,155,902 - 129,169,648 (-)NCBI
ChlSab1.1 Ensembl20129,156,067 - 129,169,597 (-)Ensembl
Vero_WHO_p1.0NW_02366605433,500,564 - 33,514,453 (-)NCBI
Rer1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248187,604,854 - 7,616,457 (-)NCBI

Position Markers
AU043380  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384155,074,467 - 155,074,559UniSTSGRCm38
MGSCv374154,448,576 - 154,448,668UniSTSGRCm37
Celera4157,346,909 - 157,347,001UniSTS
Cytogenetic Map4E2UniSTS
Whitehead/MRC_RH41995.14UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301452Elsgp1_melevated serum gp70 1 (mouse)Not determined4121615338155615442Mouse
1300933Cdcs9_mcytokine deficiency colitis susceptibility 9 (mouse)Not determined4125504302156508116Mouse
1301982Pltiq1_mphospholipid transfer protein inducibility QTL 1 (mouse)Not determined4124893970156508116Mouse
1300780Cocrb16_mcocaine related behavior 16 (mouse)Not determined4138859268156508116Mouse
1300858Tafat_mtally ho associated mesenteric fat pad weight (mouse)Not determined4124893970156508116Mouse
1300874Gasa2_mgastritis type A susceptibility locus 2 (mouse)Not determined4132926037156508116Mouse
1300621Tpnr1_mthermal pain response 1 (mouse)Not determined4125504302156508116Mouse
1300537Ap3q_malcohol preference 3 QTL (mouse)Not determined4134569994156508116Mouse
1301108Scon2_msucrose consumption 2 (mouse)Not determined4134569994156508116Mouse
4142139Adip12_madiposity 12 (mouse)Not determined4124893970156508116Mouse
10043985Stheal12_msoft tissue heal 12 (mouse)Not determined4121615338155615442Mouse
10043996Gct5_mgranulosa cell tumorigenesis 5 (mouse)Not determined4128057656156508116Mouse
10045620Heal22_mwound healing/regeneration 22 (mouse)Not determined4125504302156508116Mouse
4142481Gct1_mgranulosa cell tumorigenesis 1 (mouse)Not determined4128057656156508116Mouse
4142061Chlq16_mcirculating hormone level QTL 16 (mouse)Not determined4121615338155615442Mouse
4142077Ignpq2_mIgA nephropathy QTL 2 (mouse)Not determined4133592276156508116Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155600000Mouse
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156183778Mouse
10755531Lymph3_mlymphocyte differential 3 (mouse)4124826172156508116Mouse
11533916Mts1_mmammary tumor susceptibility 1 (mouse)4125562755156508116Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:507
Count of miRNA genes:359
Interacting mature miRNAs:419
Transcripts:ENSMUST00000030914, ENSMUST00000125357, ENSMUST00000149796
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001362981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_026395 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006539131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006539132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006539133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011250328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030253730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK002550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK003682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK013262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK018013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK078396 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK182182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL670413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC029189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM898853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY164316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000030914   ⟹   ENSMUSP00000030914
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl4155,074,110 - 155,086,373 (-)Ensembl
RefSeq Acc Id: ENSMUST00000125357
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl4155,082,688 - 155,086,382 (-)Ensembl
RefSeq Acc Id: ENSMUST00000149796
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl4155,074,110 - 155,086,371 (-)Ensembl
RefSeq Acc Id: NM_001362981   ⟹   NP_001349910
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394155,158,566 - 155,170,810 (-)NCBI
GRCm384155,074,109 - 155,086,353 (-)NCBI
Sequence:
RefSeq Acc Id: NM_026395   ⟹   NP_080671
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394155,158,566 - 155,170,810 (-)NCBI
GRCm384155,074,109 - 155,086,353 (-)NCBI
MGSCv374154,448,221 - 154,460,406 (-)RGD
Celera4157,346,554 - 157,358,733 (-)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006539131   ⟹   XP_006539194
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394155,158,566 - 155,170,828 (-)NCBI
GRCm384155,074,109 - 155,086,371 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006539132   ⟹   XP_006539195
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394155,158,566 - 155,170,814 (-)NCBI
GRCm384155,074,109 - 155,086,351 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006539133   ⟹   XP_006539196
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394155,158,566 - 155,170,751 (-)NCBI
GRCm384155,074,109 - 155,086,294 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011250328   ⟹   XP_011248630
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394155,158,566 - 155,170,840 (-)NCBI
GRCm384155,074,109 - 155,086,371 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030253730   ⟹   XP_030109590
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394155,158,566 - 155,170,782 (-)NCBI
GRCm384155,074,109 - 155,086,325 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_080671   ⟸   NM_026395
- UniProtKB: Q9CQU3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006539195   ⟸   XM_006539132
- Peptide Label: isoform X1
- UniProtKB: Q9CQU3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006539196   ⟸   XM_006539133
- Peptide Label: isoform X1
- UniProtKB: Q9CQU3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006539194   ⟸   XM_006539131
- Peptide Label: isoform X1
- UniProtKB: Q9CQU3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011248630   ⟸   XM_011250328
- Peptide Label: isoform X1
- UniProtKB: Q9CQU3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001349910   ⟸   NM_001362981
RefSeq Acc Id: XP_030109590   ⟸   XM_030253730
- Peptide Label: isoform X1
RefSeq Acc Id: ENSMUSP00000030914   ⟸   ENSMUST00000030914

Promoters
RGD ID:6836049
Promoter ID:MM_KWN:41129
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_001081100,   OTTMUST00000024728,   OTTMUST00000024729,   OTTMUST00000024730,   OTTMUST00000024750,   OTTMUST00000024751,   OTTMUST00000024753,   OTTMUST00000024754,   OTTMUST00000071215,   UC008WCV.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364154,459,526 - 154,460,657 (-)MPROMDB
RGD ID:6885760
Promoter ID:EPDNEW_M6331
Type:initiation region
Name:Rer1_1
Description:Mus musculus retention in endoplasmic reticulum sorting receptor1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384155,086,325 - 155,086,385EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1915080 AgrOrtholog
Ensembl Genes ENSMUSG00000029048 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000030914 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000030914 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000149796 ENTREZGENE
InterPro Rer1 UniProtKB/Swiss-Prot
KEGG Report mmu:67830 UniProtKB/Swiss-Prot
MGD MGI:1915080 ENTREZGENE
NCBI Gene 67830 ENTREZGENE
PANTHER PTHR10743 UniProtKB/Swiss-Prot
Pfam Rer1 UniProtKB/Swiss-Prot
PhenoGen Rer1 PhenoGen
PIRSF AtER_Rer1p UniProtKB/Swiss-Prot
UniProt Q9CQU3 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q3THP4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-29 Rer1  retention in endoplasmic reticulum sorting receptor 1    RER1 retention in endoplasmic reticulum 1 homolog (S. cerevisiae)  Symbol and/or name change 5135510 APPROVED