Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Npas4 (neuronal PAS domain protein 4) Mus musculus
Symbol: Npas4
Name: neuronal PAS domain protein 4
RGD ID: 1550814
Description: Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein heterodimerization activity. Involved in several processes, including chemical postsynaptic transmission; learning or memory; and modulation of chemical synaptic transmission. Localizes to nucleus and transcription regulator complex. Is expressed in bladder; brain; embryo; ureter; and urethra of female. Orthologous to human NPAS4 (neuronal PAS domain protein 4); INTERACTS WITH (S)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: bHLH-PAS type transcription factor NXF; HLH-PAS transcription factor NXF; LE; LE-PAS; limbic-enhanced PAS protein; N; neuronal PAS domain-containing protein 4; neuronal PAS4; Nx; Nxf
Homo sapiens (human) : NPAS4 (neuronal PAS domain protein 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Npas4 (neuronal PAS domain protein 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Npas4 (neuronal PAS domain protein 4)
Pan paniscus (bonobo/pygmy chimpanzee) : NPAS4 (neuronal PAS domain protein 4)
Canis lupus familiaris (dog) : NPAS4 (neuronal PAS domain protein 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Npas4 (neuronal PAS domain protein 4)
Sus scrofa (pig) : NPAS4 (neuronal PAS domain protein 4)
Chlorocebus sabaeus (African green monkey) : NPAS4 (neuronal PAS domain protein 4)
Heterocephalus glaber (naked mole-rat) : Npas4 (neuronal PAS domain protein 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl194,984,355 - 4,990,316 (-)EnsemblGRCm38mm10GRCm38
GRCm38194,984,353 - 5,003,439 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37194,984,355 - 4,989,971 (-)NCBIGRCm37mm9NCBIm37
MGSCv36194,984,355 - 4,989,971 (-)NCBImm8
Celera194,853,421 - 4,859,037 (-)NCBICelera
Cytogenetic Map19ANCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Npas4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1550814
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.