Or10a4 (olfactory receptor family 10 subfamily A member 4) - Rat Genome Database

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Gene: Or10a4 (olfactory receptor family 10 subfamily A member 4) Mus musculus
Analyze
Symbol: Or10a4
Name: olfactory receptor family 10 subfamily A member 4
RGD ID: 1550812
MGI Page MGI
Description: Predicted to enable olfactory receptor activity. Acts upstream of or within axon guidance. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including main olfactory bulb and nose. Orthologous to human OR10A4 (olfactory receptor family 10 subfamily A member 4).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: GA_x6K02T2PBJ9-9470146-9471093; MOR263; MOR263-5; olfactory receptor 17; olfactory receptor MOR263-5; Olfr17; P; P2; P2 olfactory receptor
RGD Orthologs
Human
Rat
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397106,696,674 - 106,697,621 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7106,692,427 - 106,699,015 (+)EnsemblGRCm39 Ensembl
GRCm387107,097,467 - 107,098,414 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7107,093,220 - 107,099,808 (+)EnsemblGRCm38mm10GRCm38
MGSCv377114,240,981 - 114,241,928 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367106,888,644 - 106,889,591 (+)NCBIMGSCv36mm8
Celera7107,116,450 - 107,117,397 (+)NCBICelera
Cytogenetic Map7E3NCBI
cM Map756.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3. Mouse MP Annotation Import Pipeline RGD automated import pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8929536   PMID:9546391   PMID:9883721   PMID:9988220   PMID:10559395   PMID:10798394   PMID:11106731   PMID:11416212   PMID:11802173   PMID:11875048   PMID:12477932   PMID:12538518  
PMID:12588732   PMID:12598627   PMID:12898607   PMID:14611657   PMID:14993187   PMID:15078553   PMID:15157418   PMID:15173589   PMID:15186780   PMID:15186781   PMID:15728829   PMID:15964824  
PMID:16859840   PMID:17347997   PMID:17350283   PMID:17521568   PMID:17537788   PMID:17581954   PMID:18022950   PMID:18303576   PMID:18367086   PMID:18854508   PMID:20080187   PMID:20550939  
PMID:20624980   PMID:20668191   PMID:20691762   PMID:20723208   PMID:21516098   PMID:21529909   PMID:21646512   PMID:21699983   PMID:21873635   PMID:22009938   PMID:22078886   PMID:22355745  
PMID:22431605   PMID:22906231   PMID:22910355   PMID:22981605   PMID:23035080   PMID:23141535   PMID:23240083   PMID:23700388   PMID:23870122   PMID:23884929   PMID:23926254   PMID:25568110  
PMID:26100963   PMID:26361056   PMID:26446231   PMID:26450880   PMID:27145700   PMID:28425486   PMID:28597915   PMID:28933695   PMID:29577883   PMID:30498219   PMID:31875544   PMID:32209480  
PMID:32295537   PMID:34879231  


Genomics

Comparative Map Data
Or10a4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397106,696,674 - 106,697,621 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7106,692,427 - 106,699,015 (+)EnsemblGRCm39 Ensembl
GRCm387107,097,467 - 107,098,414 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7107,093,220 - 107,099,808 (+)EnsemblGRCm38mm10GRCm38
MGSCv377114,240,981 - 114,241,928 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367106,888,644 - 106,889,591 (+)NCBIMGSCv36mm8
Celera7107,116,450 - 107,117,397 (+)NCBICelera
Cytogenetic Map7E3NCBI
cM Map756.1NCBI
OR10A4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38116,876,625 - 6,877,619 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl116,876,625 - 6,877,619 (+)EnsemblGRCh38hg38GRCh38
GRCh37116,897,856 - 6,898,850 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36116,854,455 - 6,855,402 (+)NCBINCBI36Build 36hg18NCBI36
Build 34116,854,454 - 6,855,402NCBI
Celera117,016,949 - 7,017,943 (+)NCBICelera
Cytogenetic Map11p15.4NCBI
HuRef116,556,433 - 6,557,427 (+)NCBIHuRef
CHM1_1116,896,792 - 6,897,786 (+)NCBICHM1_1
T2T-CHM13v2.0116,935,004 - 6,935,998 (+)NCBIT2T-CHM13v2.0
Or10a4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81170,365,682 - 170,370,100 (+)NCBIGRCr8
mRatBN7.21160,957,099 - 160,958,046 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1160,953,530 - 160,958,974 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1169,229,067 - 169,230,014 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01176,415,078 - 176,416,025 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01169,099,877 - 169,100,824 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01171,187,268 - 171,189,115 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1171,188,133 - 171,189,080 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01178,193,086 - 178,194,033 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41164,388,945 - 164,389,892 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11164,484,421 - 164,485,369 (+)NCBI
Celera1158,870,951 - 158,871,898 (+)NCBICelera
Cytogenetic Map1q33NCBI
OR10A4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12130,343,764 - 30,344,711 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2130,343,764 - 30,344,711 (+)NCBICanFam3.1canFam3CanFam3.1
ROS_Cfam_1.02131,162,275 - 31,163,222 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2131,162,275 - 31,163,222 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12130,476,164 - 30,477,111 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02130,643,552 - 30,644,499 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02130,839,120 - 30,840,067 (+)NCBIUU_Cfam_GSD_1.0
LOC101976516
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494754,832,300 - 54,833,275 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936841254,052 - 254,999 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936841254,035 - 255,004 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC106504179
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.192,628,434 - 2,636,418 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.293,149,902 - 3,169,616 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103241216
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1157,936,841 - 57,940,272 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl157,938,329 - 57,939,276 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038155,695,564 - 155,698,308 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101710297
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248178,726,441 - 8,727,388 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248178,726,441 - 8,727,388 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Or10a4
7 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:102
Count of miRNA genes:101
Interacting mature miRNAs:102
Transcripts:ENSMUST00000098138
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730199425108999207Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736280015116416877Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745161966118693530Mouse
13208555Lgth10_mbody length 10 (mouse)751649748125599172Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753249748143153737Mouse
25823170Hrsq7_mhost response to SARS QTL 7, log titer (mouse)754819589116822815Mouse
27226778Femd11_mfemur midshaft diameter 11, 16 week (mouse)756949748134001729Mouse
26884408Bzwq13_mbi-zygomatic width QTL 13, 16 week (mouse)761749748121399223Mouse
27095916Scvln15_msacral vertebrae length 2, 16 week (mouse)761749748123699223Mouse
26884440Sklq4_mskull length QTL 4, 5 week (mouse)765249748126499172Mouse
27226715Metcl3_mmetatarsal-calcaneal length 3, 5 week (mouse)767849748119499223Mouse
26884444Sklq8_mskull length QTL 8, 10 week (mouse)767849748124199223Mouse
26884451Sklq14_mskull length QTL 14, 16 week (mouse)767849748124999172Mouse
27095907Scvln4_msacral vertebrae length 2, 5 week (mouse)769949748120499223Mouse
27095910Pglq13_mpelvic girdle length QTL 13, 16 week (mouse)773049748125699172Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773149748143153737Mouse
11553869Stmm2b_mskin tumor modifier of MSM 2a (mouse)773725965107725965Mouse
27226745Metcl9_mmetatarsal-calcaneal length 9, 10 week (mouse)774849748122199223Mouse
27226781Tibl3_mtibia length 3, 5 week (mouse)774849748122199223Mouse
1301566Adip3_madiposity 3 (mouse)Not determined775394215109394346Mouse
14746989Manh62_mmandible shape 62 (mouse)775742528109742528Mouse
26884398Humsd6_mhumerus midshaft diameter 6, 16 week (mouse)778649748136901729Mouse
10412110Cctq1_mcentral corneal thickness QTL 1 (mouse)Not determined780551681114551791Mouse
4142500Morq1_mmodifier of Rs1 QTL 1 (mouse)Not determined80551681114551791Mouse
27095930Ulnl10_mulna length 10, 16 week (mouse)780849748126699172Mouse
27095923Pglq3_mpelvic girdle length QTL 3, 5 week (mouse)781249748124199223Mouse
27095903Scvln10_msacral vertebrae length 2, 10 week (mouse)781449748126499172Mouse
27226765Tibl18_mtibia length 18, 16 week (mouse)781849748126499172Mouse
27226763Feml20_mfemur length 20, 16 week (mouse)785049208124199223Mouse
1301997Cia7_mcollagen induced arthritis QTL 7 (mouse)Not determined785365595112533819Mouse
1301647Elpt_melevated leptin (mouse)Not determined786500186120500329Mouse
1301188Heal6_mwound healing/regeneration 6 (mouse)Not determined787043932121044066Mouse
1302062Stheal6_msoft tissue heal 6 (mouse)Not determined787043932121044066Mouse
13463473Hbbcq4_mhemoglobin concentration QTL 4 (mouse)787043932121044066Mouse
1301781Capsq3_mcapsaicin sensitivity related QTL 3 (mouse)Not determined787143137119485380Mouse
27226769Tibl12_mtibia length 12, 10 week (mouse)787249208126499172Mouse
27226790Feml15_mfemur length 15, 10 week (mouse)787249208126499172Mouse
27095929Pglq8_mpelvic girdle length QTL 8, 10 week (mouse)787849208108099207Mouse
1357664Nba3_mNew Zealand Black autoimmunity 3 (mouse)Not determined791482996125483156Mouse
1301937Skull10_mskull morphology 10 (mouse)Not determined791482996125483156Mouse
1300528Ssial3_msusceptibility to sialadenitis 3 (mouse)Not determined793391848127392041Mouse
1301478Eae26_msusceptibility to experimental allergic encephalomyelitis 26 (mouse)Not determined798164922132165010Mouse
13524850Asrq7_macoustic startle response 7 (mouse)798394974132394974Mouse
10412104Tons2_mtongue size 2 (mouse)Not determined799837716133837716Mouse
11039524Tbbr3_mTrypanosoma brucei brucei response 3 (mouse)7100750722134750843Mouse
1301447Fembm3_mfemoral bone morphometry 3 (mouse)Not determined7100993261134993342Mouse
1357460Vtbt4_mvertebral trabecular bone trait 4 (mouse)Not determined7101693381135693530Mouse
1301105Cfld4_mcystic fibrosis lung disease 4 (mouse)Not determined7101693381135693530Mouse
1300721Cfbw3_mcystic fibrosis body weight 3 (mouse)Not determined7101693381135693530Mouse
4142312Nilac4_mnicotine induced locomotor activity 4 (mouse)Not determined7102485219136485380Mouse
5491192Mobq1_mmultigenic obesity QTL 1 (mouse)Not determined7105250663139250811Mouse
13524852Asrq7a_macoustic startle response 7a (mouse)7105350008139350008Mouse

Markers in Region
Olfr17  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387107,097,590 - 107,098,389UniSTSGRCm38
Celera7107,116,573 - 107,117,372UniSTS
Cytogenetic Map7F2UniSTS
cM Map756.1UniSTS
UniSTS:489229  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387107,097,467 - 107,098,414UniSTSGRCm38
MGSCv377114,240,981 - 114,241,928UniSTSGRCm37
Celera7107,116,450 - 107,117,397UniSTS
Cytogenetic Map7F2UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000098138   ⟹   ENSMUSP00000095741
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7106,696,674 - 106,697,621 (+)Ensembl
GRCm38.p6 Ensembl7107,097,467 - 107,098,414 (+)Ensembl
RefSeq Acc Id: ENSMUST00000210568   ⟹   ENSMUSP00000147931
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7106,692,427 - 106,699,015 (+)Ensembl
GRCm38.p6 Ensembl7107,093,220 - 107,099,808 (+)Ensembl
RefSeq Acc Id: NM_020598   ⟹   NP_065623
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397106,696,674 - 106,697,621 (+)NCBI
GRCm387107,097,467 - 107,098,414 (+)ENTREZGENE
MGSCv377114,240,981 - 114,241,928 (+)RGD
Celera7107,116,450 - 107,117,397 (+)RGD
cM Map7 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_065623   ⟸   NM_020598
- UniProtKB: Q7TRM9 (UniProtKB/TrEMBL),   E9PVA4 (UniProtKB/TrEMBL),   Q9JKA6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000147931   ⟸   ENSMUST00000210568
RefSeq Acc Id: ENSMUSP00000095741   ⟸   ENSMUST00000098138
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7TRM9-F1-model_v2 AlphaFold Q7TRM9 1-315 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:109148 AgrOrtholog
Ensembl Genes ENSMUSG00000073897 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000098138 ENTREZGENE
  ENSMUST00000098138.5 UniProtKB/TrEMBL
  ENSMUST00000210568.4 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report mmu:18314 UniProtKB/TrEMBL
MGD MGI:109148 ENTREZGENE
NCBI Gene 18314 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR 10A4 UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or10a4 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A0M3VGY0_MOUSE UniProtKB/TrEMBL
  E9PVA4 ENTREZGENE
  Q7TRM9 ENTREZGENE, UniProtKB/TrEMBL
  Q9JKA6 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary E9PVA4 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-23 Or10a4  olfactory receptor family 10 subfamily A member 4  Olfr17  olfactory receptor 17  Symbol and/or name updated 27372883 PROVISIONAL