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Gene: Fcgr4 (Fc receptor, IgG, low affinity IV) Mus musculus
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Symbol: Fcgr4
Name: Fc receptor, IgG, low affinity IV
Description: Exhibits IgE receptor activity and IgG receptor activity. Involved in neutrophil activation and positive regulation of bone resorption. Localizes to the cell surface. Human ortholog(s) of this gene implicated in several diseases, including arthritis (multiple); autoimmune hypersensitivity disease (multiple); glomerulonephritis (multiple); hematologic cancer (multiple); and vasculitis (multiple). Is expressed in liver. Orthologous to human FCGR3A (Fc fragment of IgG receptor IIIa) and FCGR3B (Fc fragment of IgG receptor IIIb); PARTICIPATES IN Leishmaniasis pathway; Staphylococcus aureus infection pathway; systemic lupus erythematosus pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid; 3,3',5,5'-tetrabromobisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4833442P21Rik; CD16-2; Fc fragment of IgG, low affinity III, receptor for (CD16); Fc fragment of IgG, low affinity IIIa, receptor for (CD16); Fc gammaRIV; Fc receptor-like 3; FcgammaRIV; Fcgr3a; FcgRIV; Fcrl3; low affinity immunoglobulin gamma Fc region receptor III-A; low affinity immunoglobulin gamma Fc region receptor IV
Orthologs:
Homo sapiens (human) : FCGR3A (Fc fragment of IgG receptor IIIa)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fcgr3a (Fc fragment of IgG receptor IIIa)  Alliance
Canis lupus familiaris (dog) : LOC478984 (low affinity immunoglobulin gamma Fc region receptor III)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fcgr3a (Fc fragment of IgG receptor IIIa)
Sus scrofa (pig) : FCGR3A (Fc fragment of IgG receptor IIIa)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1171,018,920 - 171,029,761 (+)Ensembl
GRCm381171,018,926 - 171,029,761 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371172,949,057 - 172,959,892 (+)NCBIGRCm37mm9NCBIm37
MGSCv361172,855,614 - 172,866,426 (+)NCBImm8
Celera1173,467,124 - 173,477,978 (+)NCBICelera
Cytogenetic Map1 H3NCBI
cM Map178.53NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Fcgr4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1550776
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.