Or11h4 (olfactory receptor family 11 subfamily H member 4) - Rat Genome Database

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Gene: Or11h4 (olfactory receptor family 11 subfamily H member 4) Mus musculus
Analyze
No known orthologs.
Symbol: Or11h4
Name: olfactory receptor family 11 subfamily H member 4
RGD ID: 1550732
MGI Page MGI
Description: Predicted to enable olfactory receptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in membrane. Orthologous to human OR11H4 (olfactory receptor family 11 subfamily H member 4).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: GA_x6K02T2PMLR-6484046-6483105; MOR106; MOR106-1; odorant receptor S1; olfactory receptor 749; Olfr749; ORL461; Ors1
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391450,973,676 - 50,981,781 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1450,973,628 - 50,982,551 (-)EnsemblGRCm39 Ensembl
GRCm381450,736,219 - 50,744,324 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1450,736,171 - 50,745,094 (-)EnsemblGRCm38mm10GRCm38
MGSCv371451,355,894 - 51,363,999 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361449,658,170 - 49,659,145 (-)NCBIMGSCv36mm8
Celera1447,023,937 - 47,032,012 (-)NCBICelera
Cytogenetic Map14C1NCBI
cM Map1426.22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (ISA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10089886   PMID:11802173   PMID:11875048   PMID:14611657   PMID:21873635   PMID:23682908   PMID:26100963   PMID:32209480   PMID:32295537  


Genomics

Variants

.
Variants in Or11h4
211 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:94
Count of miRNA genes:91
Interacting mature miRNAs:93
Transcripts:ENSMUST00000074674
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301372Sluc13_msusceptibility to lung cancer 13 (mouse)Not determined141882760452827726Mouse
1357589Kdnw2_mkidney weight 2 (mouse)Not determined1420887473121269804Mouse
1357527Epfpq1_mepididymal fat percentage QTL 1 (mouse)Not determined142106245071885801Mouse
14746973Manh76_mmandible shape 76 (mouse)142228721756287217Mouse
4142485Modor2_mmodifier of ocular retardation 2 (mouse)Not determined142492624858179769Mouse
13506929Recrq10_mrecombination rate in male meiosis QTL 10 (mouse)142792195761137449Mouse
10043886Cia49_mcollagen induced arthritis QTL 49 (mouse)Not determined142999699463997133Mouse
27226744Metcl6_mmetatarsal-calcaneal length 6, 5 week (mouse)143032195752937457Mouse
27226774Tibl15_mtibia length 15, 10 week (mouse)143032195787937436Mouse
1300909Ath13_matherosclerosis 13 (mouse)Not determined143033525064335381Mouse
1300998Cia17_mcollagen induced arthritis 17 (mouse)Not determined143033525064335381Mouse
27226737Metcl12_mmetatarsal-calcaneal length 12, 10 week (mouse)143322195759437449Mouse
27226727Tibl21_mtibia length 21, 16 week (mouse)143412195752937457Mouse
1300625Cosz2_mcocaine seizure 2 (mouse)Not determined143504579768785736Mouse
10043887Cia50_mcollagen induced arthritis QTL 50 (mouse)Not determined143743018571430320Mouse
4142419Tgq26_mtriglyceride QTL 26 (mouse)Not determined4033731974337319Mouse
1301777Bglq15_mbody growth late QTL 15 (mouse)Not determined144296241676962593Mouse
1301424Skull21_mskull morphology 21 (mouse)Not determined144296241676962593Mouse
1300805Mors3_mmodifier of obesity related sterility 3 (mouse)Not determined144303727077037418Mouse
1301091Bbaa21_mB.burgdorferi-associated arthritis 21 (mouse)Not determined144306584777066045Mouse
4141400Nilac8_mnicotine induced locomotor activity 8 (mouse)Not determined144306584777066045Mouse
4141484Hcbip1_mhexachlorobenzene induced porphyria 1 (mouse)Not determined4733525059962593Mouse
1300605El5_mepilepsy 5 (mouse)Not determined144945542583455556Mouse

Markers in Region
UniSTS:492909  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381450,736,158 - 50,737,223UniSTSGRCm38
MGSCv371451,355,833 - 51,356,898UniSTSGRCm37
Celera1447,023,876 - 47,024,940UniSTS
Cytogenetic Map14C1UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000074674   ⟹   ENSMUSP00000074242
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1450,973,676 - 50,981,776 (-)Ensembl
GRCm38.p6 Ensembl1450,736,219 - 50,744,319 (-)Ensembl
RefSeq Acc Id: ENSMUST00000214290   ⟹   ENSMUSP00000150627
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1450,973,628 - 50,982,551 (-)Ensembl
GRCm38.p6 Ensembl1450,736,171 - 50,745,094 (-)Ensembl
RefSeq Acc Id: NM_020288   ⟹   NP_064684
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391450,973,676 - 50,981,781 (-)NCBI
GRCm381450,736,219 - 50,744,324 (-)ENTREZGENE
MGSCv371451,355,894 - 51,363,999 (-)RGD
Celera1447,023,937 - 47,032,012 (-)ENTREZGENE
cM Map14 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_064684   ⟸   NM_020288
- UniProtKB: E9Q438 (UniProtKB/TrEMBL),   Q7TRL6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000074242   ⟸   ENSMUST00000074674
RefSeq Acc Id: ENSMUSP00000150627   ⟸   ENSMUST00000214290
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-E9Q438-F1-model_v2 AlphaFold E9Q438 1-313 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3030583 AgrOrtholog
Ensembl Genes ENSMUSG00000059069 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000074674 ENTREZGENE
  ENSMUST00000074674.5 UniProtKB/TrEMBL
  ENSMUST00000214290.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report mmu:56858 UniProtKB/TrEMBL
MGD MGI:3030583 ENTREZGENE
NCBI Gene 56858 ENTREZGENE
PANTHER G-PROTEIN COUPLED RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR 11H4 UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or11h4 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt E9Q438 ENTREZGENE, UniProtKB/TrEMBL
  Q7TRL6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-23 Or11h4  olfactory receptor family 11 subfamily H member 4  Olfr749  olfactory receptor 749  Symbol and/or name updated 27372883 PROVISIONAL