Gaa (glucosidase, alpha, acid) - Rat Genome Database

Name: Gaa
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Gaa (glucosidase, alpha, acid) Mus musculus

Analyze

Symbol:

Gaa

Name:

glucosidase, alpha, acid

RGD ID:

1550659

MGI Page

MGI

Description:

Enables alpha-1,4-glucosidase activity. Involved in glycophagy. Acts upstream of or within several processes, including circulatory system development; diaphragm contraction; and muscle cell cellular homeostasis. Located in lysosome and membrane. Is active in autolysosome lumen. Is expressed in several structures, including central nervous system; genitourinary system; heart; sensory organ; and skeleton. Used to study glycogen storage disease II. Human ortholog(s) of this gene implicated in glycogen storage disease II. Orthologous to human GAA (alpha glucosidase).

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

acid maltase; E430018M07Rik; lysosomal alpha-glucosidase

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GAA (alpha glucosidase)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Gaa (alpha glucosidase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gaa (alpha glucosidase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GAA (alpha glucosidase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GAA (alpha glucosidase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gaa (alpha glucosidase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GAA (alpha glucosidase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GAA (alpha glucosidase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gaa (alpha glucosidase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	MGAM (maltase-glucoamylase)	HGNC	OrthoMCL
Homo sapiens (human):	SI (sucrase-isomaltase)	HGNC	OrthoMCL
Homo sapiens (human):	MGAM2 (maltase-glucoamylase 2 (putative))	HGNC	OrthoMCL
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Gaa (alpha glucosidase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	GAA (alpha glucosidase)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	gaa (glucosidase, alpha; acid (Pompe disease, glycogen storage disease type II))	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PhylomeDB\|ZFIN)
Danio rerio (zebrafish):	si:ch73-12o23.1	Alliance	DIOPT (InParanoid\|OMA\|OrthoInspector\|SonicParanoid)
Caenorhabditis elegans (roundworm):	aagr-2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector)
Xenopus tropicalis (tropical clawed frog):	gaa	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	119,158,789 - 119,176,284 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	119,158,713 - 119,176,280 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	119,267,963 - 119,285,458 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	119,267,887 - 119,285,454 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	119,129,281 - 119,147,012 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	119,084,134 - 119,101,542 (+)	NCBI		MGSCv36	mm8
Celera	11	131,012,899 - 131,030,625 (+)	NCBI		Celera
Cytogenetic Map	11	E2	NCBI
cM Map	11	83.35	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Cardiac Form of Generalized Glycogenosis (ISO)

cardiomyopathy (ISO)

COVID-19 (ISO)

dilated cardiomyopathy (ISO)

Familial Cirrhosis with Deposition of Abnormal Glycogen (ISO)

genetic disease (ISO)

glycogen storage disease (ISO)

glycogen storage disease I (ISO)

glycogen storage disease Ia (ISO)

glycogen storage disease II (IAGP,ISO)

glycogen storage disease IV (IDA,ISO)

Glycoprotein Storage Disease (ISO)

hypertrophic cardiomyopathy (ISO)

isolated elevated serum creatine phosphokinase levels (ISO)

Left Ventricular Hypertrophy (ISO)

long QT syndrome (ISO)

membranous glomerulonephritis (ISO)

muscular disease (ISO)

muscular dystrophy (ISO)

myopathy (ISO)

pityriasis rubra pilaris (ISO)

primary ciliary dyskinesia (ISO)

primary ciliary dyskinesia 15 (ISO)

Ventricular Dysfunction (ISO)

Ventricular Fibrillation (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,2-dichloroethane (EXP)

1,2-dimethylhydrazine (EXP)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (EXP)

2,2',5,5'-tetrachlorobiphenyl (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,6-dinitrotoluene (ISO)

2-acetamidofluorene (EXP)

3,4-methylenedioxymethamphetamine (EXP)

4,4'-sulfonyldiphenol (ISO)

4-amino-2,6-dinitrotoluene (ISO)

4-methylumbelliferyl beta-D-glucoside (ISO)

acrolein (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

alpha-pinene (ISO)

aristolochic acid A (ISO)

Aroclor 1254 (EXP,ISO)

azoxystrobin (ISO)

beauvericin (ISO)

benzo[a]pyrene (EXP,ISO)

benzo[b]fluoranthene (EXP)

bisphenol A (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbon nanotube (EXP)

cisplatin (ISO)

cobalt dichloride (ISO)

coumarin (ISO)

deguelin (ISO)

endosulfan (ISO)

enniatin (ISO)

epoxiconazole (EXP)

ethanol (EXP)

finasteride (ISO)

fipronil (ISO)

flutamide (ISO)

folic acid (EXP)

folpet (EXP)

fulvestrant (ISO)

genistein (ISO)

gentamycin (ISO)

hydrogen peroxide (ISO)

ivermectin (ISO)

lead diacetate (ISO)

leflunomide (ISO)

menadione (ISO)

methidathion (EXP)

N-methyl-4-phenylpyridinium (EXP,ISO)

nefazodone (ISO)

nimesulide (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

PCB138 (EXP)

perfluorooctane-1-sulfonic acid (EXP)

perfluorooctanoic acid (EXP)

phenobarbital (ISO)

picoxystrobin (ISO)

piperonyl butoxide (ISO)

pirinixic acid (EXP)

potassium chromate (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

pyrimidifen (ISO)

quercetin (ISO)

rotenone (ISO)

silicon dioxide (ISO)

sunitinib (ISO)

thioacetamide (ISO)

titanium dioxide (EXP)

trichloroethene (ISO)

Triptolide (ISO)

trovafloxacin (EXP)

tungsten (EXP)

valdecoxib (ISO)

valproic acid (ISO)

vinclozolin (ISO)

Yessotoxin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

aorta development (IMP)

carbohydrate metabolic process (IEA)

cardiac muscle contraction (ISO)

diaphragm contraction (IMP,ISO)

glycogen catabolic process (IBA,IMP,ISO)

glycogen metabolic process (IMP)

glycophagy (IMP,ISO)

heart morphogenesis (IMP)

locomotory behavior (IMP)

lysosome organization (IBA,IMP,ISO)

muscle cell cellular homeostasis (IMP)

neuromuscular process controlling balance (IMP)

neuromuscular process controlling posture (IMP)

regulation of the force of heart contraction (IMP)

striated muscle contraction (IMP)

tissue development (IMP)

vacuolar sequestering (ISO)

Cellular Component

autolysosome lumen (IMP)

intracellular membrane-bounded organelle (ISO)

lysosome (IMP,ISO,TAS)

membrane (IMP)

Molecular Function

alpha-1,4-glucosidase activity (IBA,IDA,IMP,ISO)

alpha-glucosidase activity (ISO)

carbohydrate binding (ISO)

catalytic activity (IEA)

glucan 1,6-alpha-glucosidase activity (ISO)

hydrolase activity (IEA)

hydrolase activity, acting on glycosyl bonds (IEA)

hydrolase activity, hydrolyzing O-glycosyl compounds (IEA)

maltose alpha-glucosidase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

galactose metabolic pathway (IEA,ISO)

galactosemia pathway (ISO)

starch and sucrose metabolic pathway (IEA)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal gait (IAGP)

abnormal glycogen homeostasis (IAGP)

abnormal heart shape (IAGP)

abnormal impulse conducting system conduction (IAGP)

abnormal lysosome morphology (IAGP)

abnormal lysosome physiology (IAGP)

abnormal muscle fiber morphology (IAGP)

abnormal muscle physiology (IAGP)

abnormal myocardial fiber morphology (IAGP)

abnormal QRS complex (IAGP)

abnormal sarcomere morphology (IAGP)

abnormal skeletal muscle fiber morphology (IAGP)

abnormal Z line morphology (IAGP)

cardiomyopathy (IAGP)

decreased grip strength (IAGP)

decreased locomotor activity (IAGP)

decreased skeletal muscle mass (IAGP)

decreased vertical activity (IAGP)

dilated heart left ventricle (IAGP)

dilated heart right ventricle (IAGP)

enlarged heart (IAGP)

heart left ventricle hypertrophy (IAGP)

heart right ventricle hypertrophy (IAGP)

hindlimb paralysis (IAGP)

impaired coordination (IAGP)

increased body mass index (IAGP)

increased brain glycogen level (IAGP)

increased cardiac muscle glycogen level (IAGP)

increased glycogen level (IAGP)

increased liver glycogen level (IAGP)

increased skeletal muscle glycogen level (IAGP)

kyphosis (IAGP)

muscle weakness (IAGP)

muscular atrophy (IAGP)

myopathy (IAGP)

progressive muscle weakness (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	MGDs mouse GO annotations	MGD data from the GO Consortium
2.	MGD IEA	MGD IEA
3.	Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos.	Neidhardt L, etal., Mech Dev 2000 Nov;98(1-2):77-94.
4.	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
6.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
7.	SMPDB Annotation Import Pipeline	Pipeline to import SMPDB annotations from SMPDB into RGD
8.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
9.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
11.	Alglucosidase alfa treatment alleviates liver disease in a mouse model of glycogen storage disease type IV.	Yi H, etal., Mol Genet Metab Rep. 2016 Oct 4;9:31-33. doi: 10.1016/j.ymgmr.2016.09.008. eCollection 2016 Dec.

Additional References at PubMed

PMID:24417	PMID:1794057	PMID:3540946	PMID:7323947	PMID:8449498	PMID:8530103	PMID:9384603	PMID:9668092	PMID:10233847	PMID:10349636	PMID:10547605	PMID:10838256
PMID:10922068	PMID:11042159	PMID:11076861	PMID:11217851	PMID:11328962	PMID:11425943	PMID:11590121	PMID:11785984	PMID:12115977	PMID:12409258	PMID:12477932	PMID:12739885
PMID:14681479	PMID:15169761	PMID:15207257	PMID:15356673	PMID:15489334	PMID:15674828	PMID:15747579	PMID:15782199	PMID:15839836	PMID:16005263	PMID:16141072	PMID:16141073
PMID:16602821	PMID:17022935	PMID:17027913	PMID:17245350	PMID:17510371	PMID:17572127	PMID:17826266	PMID:17924344	PMID:17937387	PMID:18307520	PMID:18505932	PMID:18648322
PMID:18782848	PMID:18799693	PMID:19167256	PMID:19959526	PMID:20080761	PMID:20223998	PMID:20385789	PMID:20413686	PMID:20554235	PMID:20861693	PMID:21179212	PMID:21267068
PMID:21397538	PMID:21677750	PMID:21699755	PMID:21747768	PMID:21873635	PMID:22154081	PMID:22494547	PMID:22815812	PMID:22851177	PMID:23041258	PMID:23342162	PMID:23457523
PMID:23606558	PMID:23726947	PMID:24154525	PMID:24448824	PMID:24897114	PMID:25036864	PMID:25044020	PMID:25217571	PMID:25231351	PMID:26733885	PMID:27017193	PMID:27113764
PMID:27358407	PMID:27614205	PMID:28170191	PMID:28245920	PMID:28336814	PMID:28378742	PMID:28874182	PMID:29118420	PMID:29187643	PMID:30457570	PMID:30550785	PMID:30713523
PMID:31693883	PMID:31793879	PMID:32325033	PMID:32428018	PMID:32587263	PMID:33039711	PMID:33214573	PMID:33883348	PMID:33953320	PMID:34737297	PMID:34850579	PMID:35351934
PMID:35682977	PMID:36517654	PMID:37085544	PMID:37366541	PMID:37371072

Genomics

Comparative Map Data

Gaa
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	119,158,789 - 119,176,284 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	119,158,713 - 119,176,280 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	119,267,963 - 119,285,458 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	119,267,887 - 119,285,454 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	119,129,281 - 119,147,012 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	119,084,134 - 119,101,542 (+)	NCBI		MGSCv36	mm8
Celera	11	131,012,899 - 131,030,625 (+)	NCBI		Celera
Cytogenetic Map	11	E2	NCBI
cM Map	11	83.35	NCBI

GAA
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	80,101,581 - 80,119,881 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	80,101,533 - 80,119,881 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	78,075,380 - 78,093,680 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	75,689,950 - 75,708,274 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	75,689,876 - 75,708,273	NCBI
Celera	17	74,704,156 - 74,722,487 (+)	NCBI		Celera
Cytogenetic Map	17	q25.3	NCBI
HuRef	17	73,516,452 - 73,534,833 (+)	NCBI		HuRef
CHM1_1	17	78,161,682 - 78,180,006 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	17	81,002,020 - 81,020,360 (+)	NCBI		T2T-CHM13v2.0

Gaa
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	10	104,529,673 - 104,546,836 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	104,529,747 - 104,546,836 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	109,632,590 - 109,649,496 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	109,095,616 - 109,112,522 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	104,450,455 - 104,467,465 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	108,395,873 - 108,412,999 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	108,395,860 - 108,413,059 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	108,007,708 - 108,024,833 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	10	103,077,652 - 103,094,623 (+)	NCBI		Celera
Cytogenetic Map	10	q32.3	NCBI

Gaa
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955506	2,764,959 - 2,783,231 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955506	2,764,959 - 2,783,231 (-)	NCBI	ChiLan1.0	ChiLan1.0

GAA
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	17	100,991,586 - 101,009,881 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	74,188,296 - 74,206,593 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	79,723,683 - 79,741,839 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	79,723,699 - 79,741,839 (+)	Ensembl	panpan1.1		panPan2

GAA
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	1,601,092 - 1,615,582 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	1,601,121 - 1,656,597 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	2,240,939 - 2,255,430 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	2,233,266 - 2,247,757 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	2,233,268 - 2,247,881 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	2,256,768 - 2,271,257 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	2,382,084 - 2,396,575 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	2,463,363 - 2,477,882 (-)	NCBI		UU_Cfam_GSD_1.0

Gaa
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	2,269,664 - 2,286,386 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936594	4,125,595 - 4,142,261 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GAA
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	2,314,591 - 2,336,988 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	2,315,807 - 2,339,867 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	2,297,287 - 2,411,558 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GAA
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	72,064,315 - 72,083,293 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	72,067,267 - 72,083,349 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666077	43,368,453 - 43,388,090 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gaa
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624801	9,217,639 - 9,235,931 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624801	9,217,633 - 9,235,931 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Gaa
629 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	1538
Count of miRNA genes:	645
Interacting mature miRNAs:	794
Transcripts:	ENSMUST00000026666, ENSMUST00000106258, ENSMUST00000106259, ENSMUST00000128753, ENSMUST00000132706, ENSMUST00000138510, ENSMUST00000143288, ENSMUST00000150562
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
14747003	Mancz9_m	mandible centroid size 9 (mouse)					11	85844911	119844911	Mouse
15039374	Adip29_m	adiposity 29 (mouse)					11	86608320	120608320	Mouse
15039376	Bw42_m	body weight QTL 42 (mouse)					11	86608320	120608320	Mouse
15014785	Mvlq1_m	macrovesicular liver lesion QTL 1 (mouse)					11	86608320	120608320	Mouse
27226789	Feml16_m	femur length 16, 10 week (mouse)					11	87490826	121873369	Mouse
10044007	Hbnr14_m	Heligmosomoides bakeri nematode resistance 14 (mouse)			Not determined		11	87502600	121502698	Mouse
11251723	Ewc5_m	ethanol withdrawal and consumption 5 (mouse)					11	89869251	121973369	Mouse
1558753	Ath19_m	atherosclerosis 19 (mouse)			Not determined		11	91604608	121973369	Mouse
1302034	Pkccl_m	protein kinase C content in lungs (mouse)			Not determined		11	91604608	121973369	Mouse
1301095	El6_m	epilepsy 6 (mouse)			Not determined		11	93229183	121973369	Mouse
1301958	Alcp18_m	alcohol preference locus 18 (mouse)			Not determined		11	95403965	121973369	Mouse
1300944	Alcp20_m	alcohol preference locus 20 (mouse)			Not determined		11	95403965	121973369	Mouse
1300962	Cd8mts4_m	CD8 memory T cell subset 4 (mouse)			Not determined		11	96137674	121973369	Mouse
1301057	Nidd4_m	non-insulin-dependent diabetes mellitus 4 (mouse)			Not determined		11	96810136	121973369	Mouse
1301983	Berr2_m	berghei resistance locus 2 (mouse)			Not determined		11	98352609	121973369	Mouse
10043976	Obq33_m	obesity QTL 33 (mouse)			Not determined		11	98500469	121973369	Mouse
10044001	Alcw8_m	alcohol withdrawal 8 (mouse)			Not determined		11	99254187	121973369	Mouse
11553867	Stmm5_m	skin tumor modifier of MSM 5 (mouse)					11	100058103	121973369	Mouse
11341721	Rvfs2_m	Rift Valley fever susceptibility 2 (mouse)					11	100254186	120887165	Mouse
1301012	Vispl_m	visual placing (mouse)			Not determined		11	101022590	121973369	Mouse

Markers in Region

Gaa

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	11	D-E	UniSTS
cM Map	11	74.0	UniSTS

Gaa

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	11	D-E	UniSTS

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001159324	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_008064	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AI415624	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK052211	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK054057	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK088481	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK139333	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK140042	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK141546	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK145631	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK146538	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK150970	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK177279	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK179414	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK179647	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK179846	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK180575	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK180831	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK181354	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK186000	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK191262	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK191415	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK192147	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK193059	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK195564	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK196036	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK197627	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK197764	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK204050	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK204650	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK204661	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK206628	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK206897	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK207669	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK209790	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK210560	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK212044	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK214458	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK214876	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK215770	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL672140	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BB839328	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC010210	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BP767732	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BY017338	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BY335754	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466558	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U49351	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSMUST00000026666 ⟹ ENSMUSP00000026666

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	11	119,158,852 - 119,176,280 (+)	Ensembl
GRCm38.p6 Ensembl	11	119,268,026 - 119,285,454 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000106258 ⟹ ENSMUSP00000101865

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	11	119,158,854 - 119,164,278 (+)	Ensembl
GRCm38.p6 Ensembl	11	119,268,028 - 119,273,452 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000106259 ⟹ ENSMUSP00000101866

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	11	119,158,713 - 119,176,280 (+)	Ensembl
GRCm38.p6 Ensembl	11	119,267,887 - 119,285,454 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000128753

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	11	119,161,342 - 119,165,965 (+)	Ensembl
GRCm38.p6 Ensembl	11	119,270,516 - 119,275,139 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000132706 ⟹ ENSMUSP00000119702

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	11	119,165,394 - 119,169,152 (+)	Ensembl
GRCm38.p6 Ensembl	11	119,274,568 - 119,278,326 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000138510

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	11	119,169,702 - 119,170,314 (+)	Ensembl
GRCm38.p6 Ensembl	11	119,278,876 - 119,279,488 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000143288 ⟹ ENSMUSP00000121984

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	11	119,168,540 - 119,172,261 (+)	Ensembl
GRCm38.p6 Ensembl	11	119,277,714 - 119,281,435 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000150562 ⟹ ENSMUSP00000115128

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	11	119,165,682 - 119,166,446 (+)	Ensembl
GRCm38.p6 Ensembl	11	119,274,856 - 119,275,620 (+)	Ensembl

RefSeq Acc Id:

NM_001159324 ⟹ NP_001152796

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	11	119,158,789 - 119,176,284 (+)	NCBI
GRCm38	11	119,267,963 - 119,285,458 (+)	NCBI
MGSCv37	11	119,129,281 - 119,147,012 (+)	RGD
Celera	11	131,012,899 - 131,030,625 (+)	RGD
cM Map	11		ENTREZGENE

Sequence:

show sequence

ACACGGACTCCGCCGCCTACGCAGGAGGTCGTGTGACGAGGTCCGCGCGGACGAGCCCCGCCCA
CAGACCACGTGACCCACGCTGCCCGCTGAGCCTGGGGGTCTTCGGCCTGGAGGGTGATTGCGCA
GGCCTTCAGAAGTATTCATGCTGCCCCGAACCAACAGGCTTTCACCATGAATATACGGAAGCCC
CTCTGTTCGAACTCCGTGGTTGGGGCCTGCACCCTTATCTCTCTGACTACAGCGGTCATCCTGG
GTCATCTCATGCTTCGGGAGTTAATGCTGCTTCCCCAAGACCTTCATGAGTCCTCTTCAGGACT
GTGGAAGACGTACCGACCTCACCACCAGGAAGGTTACAAGCCAGGGCCTCTGCACATCCAGGAG
CAGACTGAACAGCCCAAAGAAGCACCCACACAGTGTGATGTGCCCCCCAGCAGCCGCTTTGACT
GTGCCCCCGACAAAGGCATCTCACAGGAGCAATGCGAGGCCCGCGGCTGCTGCTATGTCCCAGC
AGGGCAGGTGCTGAAGGAGCCGCAGATAGGGCAGCCCTGGTGTTTCTTCCCTCCCAGCTACCCA
AGCTACCGTCTAGAGAACCTGAGCTCTACAGAGTCGGGGTACACAGCCACCCTGACCCGTACCA
GCCCGACCTTCTTCCCAAAGGATGTGCTGACCTTACAGCTGGAGGTGCTGATGGAGACAGACAG
CCGCCTCCACTTCAAGATCAAAGATCCTGCTAGTAAGCGCTACGAAGTGCCCCTGGAGACCCCA
CGTGTGCTGAGCCAGGCACCATCCCCACTTTACAGCGTGGAATTCTCAGAGGAACCCTTTGGAG
TGATCGTTCGTAGGAAGCTTGGTGGCCGAGTGTTGCTGAACACAACCGTGGCCCCCCTGTTCTT
CGCTGACCAGTTCCTGCAGCTGTCCACTTCCCTGCCCTCCCAGCACATCACAGGCCTGGGGGAA
CACCTCAGCCCACTCATGCTCAGCACCGACTGGGCTCGTATCACCCTCTGGAACCGGGACACAC
CACCCTCGCAAGGTACCAACCTCTACGGGTCACATCCTTTCTACCTGGCACTGGAGGACGGTGG
CTTGGCTCACGGTGTCTTCTTGCTAAACAGCAATGCCATGGATGTCATCCTGCAACCCAGCCCA
GCCCTAACCTGGAGGTCAACGGGCGGGATCCTGGATGTGTATGTGTTCCTAGGCCCAGAGCCCA
AGAGCGTTGTGCAACAATACCTGGATGTTGTGGGATACCCCTTCATGCCTCCATACTGGGGCCT
CGGCTTCCACCTCTGCCGCTGGGGCTACTCCTCGACCGCCATTGTCCGCCAGGTAGTGGAGAAC
ATGACCAGGACACACTTCCCGCTGGACGTGCAATGGAATGACCTGGACTACATGGACGCCCGAA
GAGACTTCACCTTCAACCAGGACAGCTTTGCCGACTTCCCAGACATGGTGCGGGAGCTGCACCA
GGATGGCCGGCGCTACATGATGATCGTGGACCCTGCCATCAGCAGCGCAGGCCCTGCTGGGAGT
TACAGGCCCTACGACGAGGGTCTGCGGAGGGGCGTGTTCATCACCAACGAGACTGGGCAGCCGC
TGATTGGGAAGGTTTGGCCTGGAACCACCGCCTTCCCTGATTTCACCAACCCTGAGACCCTTGA
CTGGTGGCAGGACATGGTGTCTGAGTTCCACGCCCAGGTGCCCTTCGATGGCATGTGGCTCGAC
ATGAACGAACCGTCCAACTTCGTTAGAGGCTCTCAGCAGGGCTGCCCCAACAATGAACTGGAGA
ACCCCCCCTATGTGCCCGGGGTGGTTGGCGGGATCTTGCAGGCAGCCACCATCTGTGCCTCCAG
CCACCAATTCCTCTCCACACACTACAACCTCCACAACCTGTACGGCCTCACTGAAGCTATCGCC
TCCAGCAGGGCCCTGGTCAAGACTCGGGGAACACGACCCTTTGTGATCTCCCGCTCAACCTTCT
CGGGCCACGGCCGGTACGCTGGTCACTGGACAGGGGATGTGCGGAGCTCTTGGGAGCATCTTGC
ATACTCTGTGCCAGACATCCTGCAGTTCAACCTGCTGGGCGTGCCCCTGGTCGGGGCGGACATC
TGCGGCTTCATAGGAGACACGTCAGAAGAGCTGTGTGTGCGCTGGACCCAGTTGGGGGCCTTCT
ACCCCTTCATGCGGAACCACAATGACCTGAATAGCGTGCCTCAGGAGCCGTACAGGTTCAGCGA
GACGGCGCAGCAGGCCATGAGGAAGGCCTTCGCCTTACGCTATGCCCTTCTGCCCTACCTGTAC
ACTCTCTTCCACCGCGCCCACGTCAGAGGAGACACGGTGGCCCGGCCCCTCTTCCTGGAGTTCC
CTGAGGATCCCAGCACCTGGTCTGTGGACCGCCAGCTCTTGTGGGGGCCGGCCCTGCTCATCAC
ACCTGTGCTTGAGCCTGGGAAAACTGAAGTGACGGGCTACTTCCCCAAGGGCACGTGGTACAAC
ATGCAGATGGTGTCAGTGGATTCCCTCGGTACTCTCCCTTCTCCATCATCGGCTTCATCCTTCA
GATCTGCTGTCCAGAGCAAGGGGCAGTGGCTGACACTGGAAGCCCCACTGGATACCATCAACGT
GCACCTGAGGGAGGGGTACATCATACCGCTGCAGGGTCCCAGCCTCACAACCACGGAGTCCCGA
AAGCAGCCCATGGCTCTGGCTGTGGCATTAACAGCAAGCGGCGAGGCCGATGGGGAGCTGTTCT
GGGACGACGGGGAGAGCCTCGCGGTTCTGGAGCGTGGGGCCTACACACTGGTCACCTTCTCAGC
CAAGAACAATACCATTGTGAACAAGTTAGTGCGTGTGACCAAGGAGGGAGCTGAGCTACAACTG
AGGGAGGTGACCGTCTTGGGAGTGGCCACAGCTCCTACCCAGGTCCTTTCCAACGGCATCCCTG
TCTCCAATTTCACCTACAGCCCTGACAACAAGAGCCTGGCCATCCCTGTCTCACTGCTGATGGG
AGAGCTGTTTCAAATCAGCTGGTCCTAGGAGAGTCCGTCGTTTACAGAGGCCTCCAGGGAGGCA
GAGGGAGCTTGAGCTGGCTCTGGCTGGTGGCTCCTGTAAGGACCTGCGTCCTGCTCTCCTGACA
CATCTTTGAGCTTTTCCCACCGTGTTACTGCATGCGCCCCTGAAGCTCTGTGTTCTTAGGAGAG
TGAGGCTCGCCTCACCTGCCCCACCCCAGCTGTCTGTCCCTCACCTGGCACTAGAGAATGTGGA
GCTCGGCGTGGGGACATCGTGTCTGCACCAACATCAGGCTGTGCAGCCACTGCAGCCGCAACCC
TGCAGAGACAGAGCTGGTGCCTTCACCAGGTTCCCAAGACTCGAGAAACTTACTGTGAAGTGTA
CTTACTTTTAATAAAAAGGATATTGTTTGGAAGCAGTTAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_008064 ⟹ NP_032090

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	11	119,158,789 - 119,176,284 (+)	NCBI
GRCm38	11	119,267,963 - 119,285,458 (+)	NCBI
MGSCv37	11	119,129,281 - 119,147,012 (+)	RGD
Celera	11	131,012,899 - 131,030,625 (+)	RGD
cM Map	11		ENTREZGENE

Sequence:

show sequence

ACACGGACTCCGCCGCCTACGCAGGAGGTCGTGTGACGAGGTCCGCGCGGACGAGCCCCGCCCA
CAGACCACGTGACCCACGCTGCCCGCTGAGCCTGGGGGTCTTCGGCCTGGAGGGTGATTGCGCA
GGTGAGCTGGGCGAGCTGGTGAAGGCTGTCTCCGGCCCCAGAGCCTCCGGAGGAGCGGCCTCCT
CCAGGCAGGCAGGGCCGACTGTCAGCGAGTTCCTGCTTTGGAGAATCGAGCAGAGACACGCGGC
ATAGGCCTTCAGAAGTATTCATGCTGCCCCGAACCAACAGGCTTTCACCATGAATATACGGAAG
CCCCTCTGTTCGAACTCCGTGGTTGGGGCCTGCACCCTTATCTCTCTGACTACAGCGGTCATCC
TGGGTCATCTCATGCTTCGGGAGTTAATGCTGCTTCCCCAAGACCTTCATGAGTCCTCTTCAGG
ACTGTGGAAGACGTACCGACCTCACCACCAGGAAGGTTACAAGCCAGGGCCTCTGCACATCCAG
GAGCAGACTGAACAGCCCAAAGAAGCACCCACACAGTGTGATGTGCCCCCCAGCAGCCGCTTTG
ACTGTGCCCCCGACAAAGGCATCTCACAGGAGCAATGCGAGGCCCGCGGCTGCTGCTATGTCCC
AGCAGGGCAGGTGCTGAAGGAGCCGCAGATAGGGCAGCCCTGGTGTTTCTTCCCTCCCAGCTAC
CCAAGCTACCGTCTAGAGAACCTGAGCTCTACAGAGTCGGGGTACACAGCCACCCTGACCCGTA
CCAGCCCGACCTTCTTCCCAAAGGATGTGCTGACCTTACAGCTGGAGGTGCTGATGGAGACAGA
CAGCCGCCTCCACTTCAAGATCAAAGATCCTGCTAGTAAGCGCTACGAAGTGCCCCTGGAGACC
CCACGTGTGCTGAGCCAGGCACCATCCCCACTTTACAGCGTGGAATTCTCAGAGGAACCCTTTG
GAGTGATCGTTCGTAGGAAGCTTGGTGGCCGAGTGTTGCTGAACACAACCGTGGCCCCCCTGTT
CTTCGCTGACCAGTTCCTGCAGCTGTCCACTTCCCTGCCCTCCCAGCACATCACAGGCCTGGGG
GAACACCTCAGCCCACTCATGCTCAGCACCGACTGGGCTCGTATCACCCTCTGGAACCGGGACA
CACCACCCTCGCAAGGTACCAACCTCTACGGGTCACATCCTTTCTACCTGGCACTGGAGGACGG
TGGCTTGGCTCACGGTGTCTTCTTGCTAAACAGCAATGCCATGGATGTCATCCTGCAACCCAGC
CCAGCCCTAACCTGGAGGTCAACGGGCGGGATCCTGGATGTGTATGTGTTCCTAGGCCCAGAGC
CCAAGAGCGTTGTGCAACAATACCTGGATGTTGTGGGATACCCCTTCATGCCTCCATACTGGGG
CCTCGGCTTCCACCTCTGCCGCTGGGGCTACTCCTCGACCGCCATTGTCCGCCAGGTAGTGGAG
AACATGACCAGGACACACTTCCCGCTGGACGTGCAATGGAATGACCTGGACTACATGGACGCCC
GAAGAGACTTCACCTTCAACCAGGACAGCTTTGCCGACTTCCCAGACATGGTGCGGGAGCTGCA
CCAGGATGGCCGGCGCTACATGATGATCGTGGACCCTGCCATCAGCAGCGCAGGCCCTGCTGGG
AGTTACAGGCCCTACGACGAGGGTCTGCGGAGGGGCGTGTTCATCACCAACGAGACTGGGCAGC
CGCTGATTGGGAAGGTTTGGCCTGGAACCACCGCCTTCCCTGATTTCACCAACCCTGAGACCCT
TGACTGGTGGCAGGACATGGTGTCTGAGTTCCACGCCCAGGTGCCCTTCGATGGCATGTGGCTC
GACATGAACGAACCGTCCAACTTCGTTAGAGGCTCTCAGCAGGGCTGCCCCAACAATGAACTGG
AGAACCCCCCCTATGTGCCCGGGGTGGTTGGCGGGATCTTGCAGGCAGCCACCATCTGTGCCTC
CAGCCACCAATTCCTCTCCACACACTACAACCTCCACAACCTGTACGGCCTCACTGAAGCTATC
GCCTCCAGCAGGGCCCTGGTCAAGACTCGGGGAACACGACCCTTTGTGATCTCCCGCTCAACCT
TCTCGGGCCACGGCCGGTACGCTGGTCACTGGACAGGGGATGTGCGGAGCTCTTGGGAGCATCT
TGCATACTCTGTGCCAGACATCCTGCAGTTCAACCTGCTGGGCGTGCCCCTGGTCGGGGCGGAC
ATCTGCGGCTTCATAGGAGACACGTCAGAAGAGCTGTGTGTGCGCTGGACCCAGTTGGGGGCCT
TCTACCCCTTCATGCGGAACCACAATGACCTGAATAGCGTGCCTCAGGAGCCGTACAGGTTCAG
CGAGACGGCGCAGCAGGCCATGAGGAAGGCCTTCGCCTTACGCTATGCCCTTCTGCCCTACCTG
TACACTCTCTTCCACCGCGCCCACGTCAGAGGAGACACGGTGGCCCGGCCCCTCTTCCTGGAGT
TCCCTGAGGATCCCAGCACCTGGTCTGTGGACCGCCAGCTCTTGTGGGGGCCGGCCCTGCTCAT
CACACCTGTGCTTGAGCCTGGGAAAACTGAAGTGACGGGCTACTTCCCCAAGGGCACGTGGTAC
AACATGCAGATGGTGTCAGTGGATTCCCTCGGTACTCTCCCTTCTCCATCATCGGCTTCATCCT
TCAGATCTGCTGTCCAGAGCAAGGGGCAGTGGCTGACACTGGAAGCCCCACTGGATACCATCAA
CGTGCACCTGAGGGAGGGGTACATCATACCGCTGCAGGGTCCCAGCCTCACAACCACGGAGTCC
CGAAAGCAGCCCATGGCTCTGGCTGTGGCATTAACAGCAAGCGGCGAGGCCGATGGGGAGCTGT
TCTGGGACGACGGGGAGAGCCTCGCGGTTCTGGAGCGTGGGGCCTACACACTGGTCACCTTCTC
AGCCAAGAACAATACCATTGTGAACAAGTTAGTGCGTGTGACCAAGGAGGGAGCTGAGCTACAA
CTGAGGGAGGTGACCGTCTTGGGAGTGGCCACAGCTCCTACCCAGGTCCTTTCCAACGGCATCC
CTGTCTCCAATTTCACCTACAGCCCTGACAACAAGAGCCTGGCCATCCCTGTCTCACTGCTGAT
GGGAGAGCTGTTTCAAATCAGCTGGTCCTAGGAGAGTCCGTCGTTTACAGAGGCCTCCAGGGAG
GCAGAGGGAGCTTGAGCTGGCTCTGGCTGGTGGCTCCTGTAAGGACCTGCGTCCTGCTCTCCTG
ACACATCTTTGAGCTTTTCCCACCGTGTTACTGCATGCGCCCCTGAAGCTCTGTGTTCTTAGGA
GAGTGAGGCTCGCCTCACCTGCCCCACCCCAGCTGTCTGTCCCTCACCTGGCACTAGAGAATGT
GGAGCTCGGCGTGGGGACATCGTGTCTGCACCAACATCAGGCTGTGCAGCCACTGCAGCCGCAA
CCCTGCAGAGACAGAGCTGGTGCCTTCACCAGGTTCCCAAGACTCGAGAAACTTACTGTGAAGT
GTACTTACTTTTAATAAAAAGGATATTGTTTGGAAGCAGTTAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001152796	(Get FASTA)	NCBI Sequence Viewer
	NP_032090	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB06943	(Get FASTA)	NCBI Sequence Viewer
	AAH10210	(Get FASTA)	NCBI Sequence Viewer
	BAC34888	(Get FASTA)	NCBI Sequence Viewer
	BAC40382	(Get FASTA)	NCBI Sequence Viewer
	BAE23960	(Get FASTA)	NCBI Sequence Viewer
	BAE27243	(Get FASTA)	NCBI Sequence Viewer
	BAE30001	(Get FASTA)	NCBI Sequence Viewer
	EDL34691	(Get FASTA)	NCBI Sequence Viewer
	EDL34692	(Get FASTA)	NCBI Sequence Viewer
	P70699	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_032090 ⟸ NM_008064
- Peptide Label:	preproprotein
- UniProtKB:	Q8BGI6 (UniProtKB/Swiss-Prot), Q3UJB2 (UniProtKB/Swiss-Prot), Q91Z45 (UniProtKB/Swiss-Prot), P70699 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MNIRKPLCSNSVVGACTLISLTTAVILGHLMLRELMLLPQDLHESSSGLWKTYRPHHQEGYKPG PLHIQEQTEQPKEAPTQCDVPPSSRFDCAPDKGISQEQCEARGCCYVPAGQVLKEPQIGQPWCF FPPSYPSYRLENLSSTESGYTATLTRTSPTFFPKDVLTLQLEVLMETDSRLHFKIKDPASKRYE VPLETPRVLSQAPSPLYSVEFSEEPFGVIVRRKLGGRVLLNTTVAPLFFADQFLQLSTSLPSQH ITGLGEHLSPLMLSTDWARITLWNRDTPPSQGTNLYGSHPFYLALEDGGLAHGVFLLNSNAMDV ILQPSPALTWRSTGGILDVYVFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAIV RQVVENMTRTHFPLDVQWNDLDYMDARRDFTFNQDSFADFPDMVRELHQDGRRYMMIVDPAISS AGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGTTAFPDFTNPETLDWWQDMVSEFHAQVPF DGMWLDMNEPSNFVRGSQQGCPNNELENPPYVPGVVGGILQAATICASSHQFLSTHYNLHNLYG LTEAIASSRALVKTRGTRPFVISRSTFSGHGRYAGHWTGDVRSSWEHLAYSVPDILQFNLLGVP LVGADICGFIGDTSEELCVRWTQLGAFYPFMRNHNDLNSVPQEPYRFSETAQQAMRKAFALRYA LLPYLYTLFHRAHVRGDTVARPLFLEFPEDPSTWSVDRQLLWGPALLITPVLEPGKTEVTGYFP KGTWYNMQMVSVDSLGTLPSPSSASSFRSAVQSKGQWLTLEAPLDTINVHLREGYIIPLQGPSL TTTESRKQPMALAVALTASGEADGELFWDDGESLAVLERGAYTLVTFSAKNNTIVNKLVRVTKE GAELQLREVTVLGVATAPTQVLSNGIPVSNFTYSPDNKSLAIPVSLLMGELFQISWS hide sequence

RefSeq Acc Id:	NP_001152796 ⟸ NM_001159324
- Peptide Label:	preproprotein
- UniProtKB:	Q8BGI6 (UniProtKB/Swiss-Prot), Q3UJB2 (UniProtKB/Swiss-Prot), Q91Z45 (UniProtKB/Swiss-Prot), P70699 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MNIRKPLCSNSVVGACTLISLTTAVILGHLMLRELMLLPQDLHESSSGLWKTYRPHHQEGYKPG PLHIQEQTEQPKEAPTQCDVPPSSRFDCAPDKGISQEQCEARGCCYVPAGQVLKEPQIGQPWCF FPPSYPSYRLENLSSTESGYTATLTRTSPTFFPKDVLTLQLEVLMETDSRLHFKIKDPASKRYE VPLETPRVLSQAPSPLYSVEFSEEPFGVIVRRKLGGRVLLNTTVAPLFFADQFLQLSTSLPSQH ITGLGEHLSPLMLSTDWARITLWNRDTPPSQGTNLYGSHPFYLALEDGGLAHGVFLLNSNAMDV ILQPSPALTWRSTGGILDVYVFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAIV RQVVENMTRTHFPLDVQWNDLDYMDARRDFTFNQDSFADFPDMVRELHQDGRRYMMIVDPAISS AGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGTTAFPDFTNPETLDWWQDMVSEFHAQVPF DGMWLDMNEPSNFVRGSQQGCPNNELENPPYVPGVVGGILQAATICASSHQFLSTHYNLHNLYG LTEAIASSRALVKTRGTRPFVISRSTFSGHGRYAGHWTGDVRSSWEHLAYSVPDILQFNLLGVP LVGADICGFIGDTSEELCVRWTQLGAFYPFMRNHNDLNSVPQEPYRFSETAQQAMRKAFALRYA LLPYLYTLFHRAHVRGDTVARPLFLEFPEDPSTWSVDRQLLWGPALLITPVLEPGKTEVTGYFP KGTWYNMQMVSVDSLGTLPSPSSASSFRSAVQSKGQWLTLEAPLDTINVHLREGYIIPLQGPSL TTTESRKQPMALAVALTASGEADGELFWDDGESLAVLERGAYTLVTFSAKNNTIVNKLVRVTKE GAELQLREVTVLGVATAPTQVLSNGIPVSNFTYSPDNKSLAIPVSLLMGELFQISWS hide sequence

RefSeq Acc Id:

ENSMUSP00000115128 ⟸ ENSMUST00000150562

RefSeq Acc Id:

ENSMUSP00000026666 ⟸ ENSMUST00000026666

RefSeq Acc Id:

ENSMUSP00000121984 ⟸ ENSMUST00000143288

RefSeq Acc Id:

ENSMUSP00000119702 ⟸ ENSMUST00000132706

RefSeq Acc Id:

ENSMUSP00000101865 ⟸ ENSMUST00000106258

RefSeq Acc Id:

ENSMUSP00000101866 ⟸ ENSMUST00000106259

Protein Domains

P-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P70699-F1-model_v2	AlphaFold	P70699	1-953	view protein structure

Promoters

RGD ID:

6820907

Promoter ID:

MM_KWN:10824

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, Kidney, Liver, Lung, MEF_B4, Spleen

Transcripts:

ENSMUST00000106258, NM_001159324, OTTMUST00000008875

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	11	119,129,161 - 119,129,661 (+)	MPROMDB

RGD ID:

6820906

Promoter ID:

MM_KWN:10825

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Spleen

Transcripts:

ENSMUST00000106256, OTTMUST00000008878

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	11	119,131,726 - 119,132,226 (+)	MPROMDB

RGD ID:

6820908

Promoter ID:

MM_KWN:10826

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Brain

Transcripts:

OTTMUST00000008879, OTTMUST00000008880

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	11	119,135,991 - 119,136,491 (+)	MPROMDB

RGD ID:

6820910

Promoter ID:

MM_KWN:10827

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Brain

Transcripts:

OTTMUST00000008882

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	11	119,138,091 - 119,138,591 (+)	MPROMDB

RGD ID:

6820909

Promoter ID:

MM_KWN:10828

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Brain

Transcripts:

OTTMUST00000008881

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	11	119,140,141 - 119,140,641 (+)	MPROMDB

RGD ID:

6846838

Promoter ID:

MM_ACW:9573

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Brain

Transcripts:

GAA.KSEP07-UNSPLICED

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	11	119,144,791 - 119,145,291 (+)	MPROMDB

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:95609	AgrOrtholog
Ensembl Genes	ENSMUSG00000025579	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSMUSP00000026666	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSMUSP00000101865.2	UniProtKB/TrEMBL
	ENSMUSP00000101866	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSMUSP00000115128.2	UniProtKB/TrEMBL
	ENSMUSP00000119702.2	UniProtKB/TrEMBL
	ENSMUSP00000121984.2	UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000026666	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSMUST00000106258.2	UniProtKB/TrEMBL
	ENSMUST00000106259	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSMUST00000132706.8	UniProtKB/TrEMBL
	ENSMUST00000143288.2	UniProtKB/TrEMBL
	ENSMUST00000150562.2	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.1180	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	4.10.110.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glycosidases	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	glycosyl hydrolase (family 31)	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Gal_mutarotase_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Gal_mutarotase_sf_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glyco_hydro_31	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glyco_hydro_31_AS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glyco_hydro_31_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glyco_hydro_31_N_dom	UniProtKB/Swiss-Prot
	Glyco_hydro_b	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glycoside_hydrolase_SF	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	P_trefoil_chordata	UniProtKB/TrEMBL
	P_trefoil_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	P_trefoil_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	P_trefoil_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:14387	UniProtKB/Swiss-Prot
MGD	MGI:95609	ENTREZGENE
NCBI Gene	14387	ENTREZGENE
PANTHER	ALPHA-GLUCOSIDASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	INTESTINAL TREFOIL FACTOR-RELATED	UniProtKB/TrEMBL
	LYSOSOMAL ALPHA-GLUCOSIDASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	P-TYPE DOMAIN-CONTAINING PROTEIN	UniProtKB/TrEMBL
Pfam	Gal_mutarotas_2	UniProtKB/Swiss-Prot
	Glyco_hydro_31	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	NtCtMGAM_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Trefoil	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Gaa	PhenoGen
PROSITE	GLYCOSYL_HYDROL_F31_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GLYCOSYL_HYDROL_F31_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	P_TREFOIL_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	P_TREFOIL_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROKAR_LIPOPROTEIN	UniProtKB/TrEMBL
SMART	SM00018	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	Glycosyl hydrolase domain	UniProtKB/Swiss-Prot
	SSF51445	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF57492	UniProtKB/TrEMBL
	SSF74650	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A2AFL3_MOUSE	UniProtKB/TrEMBL
	A2AFL5_MOUSE	UniProtKB/TrEMBL
	F6R5R5_MOUSE	UniProtKB/TrEMBL
	F6VEG4_MOUSE	UniProtKB/TrEMBL
	LYAG_MOUSE	UniProtKB/Swiss-Prot, ENTREZGENE
	Q3UJB2	ENTREZGENE
	Q8BGI6	ENTREZGENE
	Q91Z45	ENTREZGENE
UniProt Secondary	Q3UJB2	UniProtKB/Swiss-Prot
	Q8BGI6	UniProtKB/Swiss-Prot
	Q91Z45	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)

Mammalian Phenotype

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)

Mammalian Phenotype