Or8s8 (olfactory receptor family 8 subfamily S member 8) - Rat Genome Database

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Pathways
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Gene: Or8s8 (olfactory receptor family 8 subfamily S member 8) Mus musculus
Analyze
No known orthologs.
Symbol: Or8s8
Name: olfactory receptor family 8 subfamily S member 8
RGD ID: 1550597
MGI Page MGI
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in nasal septum epithelium and septal olfactory organ.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: GA_x6K02T2NBG7-5275017-5274082; MOR160; MOR160-5; olfactory receptor 281; olfactory receptor MOR160-5; Olfr281
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391598,354,193 - 98,355,128 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1598,350,469 - 98,358,276 (+)EnsemblGRCm39 Ensembl
GRCm381598,456,312 - 98,457,247 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1598,452,588 - 98,460,395 (+)EnsemblGRCm38mm10GRCm38
MGSCv371598,286,743 - 98,287,678 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361598,284,346 - 98,285,281 (+)NCBIMGSCv36mm8
Celera15100,611,120 - 100,612,055 (+)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1554.46NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11802173   PMID:11875048   PMID:12477932   PMID:14611657   PMID:16602821   PMID:18214836   PMID:21873635   PMID:32295537  


Genomics

Variants

.
Variants in Or8s8
31 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:125
Count of miRNA genes:122
Interacting mature miRNAs:124
Transcripts:ENSMUST00000109163
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402203102896555Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800146102008435Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578416103425899Mouse
26884397Humsd5_mhumerus midshaft diameter 5, 10 week (mouse)154836339698397881Mouse
26884399Humsd1_mhumerus midshaft diameter 1, 5 week (mouse)1548363396101708435Mouse
1302074Bmd4_mbone mineral density 4 (mouse)Not determined1556186708103425899Mouse
1302197Bhr2_mbronchial hyperresponsiveness 2 (mouse)Not determined1564306334103425899Mouse
4141135Cia35_mcollagen induced arthritis 35 (mouse)Not determined156481182698811946Mouse
1301119Drb7_mdopamine receptor binding 7 (mouse)Not determined156533657899341028Mouse
1301171Brm2_mbrachyury modifier 2 (mouse)Not determined156552537699525499Mouse
4141921Pstc3_mperiosteal circumference 3 (mouse)Not determined1567270698101270847Mouse
1300627Sluc26_msusceptibility to lung cancer 26 (mouse)Not determined1570345653104073951Mouse
1300648Dbsty4_mdiabesity 4 (mouse)Not determined1570349271104073951Mouse
1300726Pitm4_mprion incubation time 4 (mouse)Not determined1570349271104073951Mouse
14747011Mancz13_mmandible centroid size 13 (mouse)1572382669104073951Mouse
12791003Aath8_maortic arch atherosclerosis 8 (mouse)1573430144104073951Mouse
1300851Heal4_mwound healing/regeneration 4 (mouse)Not determined1577527592104073951Mouse
4142060W3q6_mweight 3 weeks QTL 6 (mouse)Not determined78601103102901704Mouse
1357894Epfpq3_mepididymal fat percentage QTL 3 (mouse)Not determined1578601103102901704Mouse
14928306Manh79_mmandible shape 79 (mouse)1578847557104073951Mouse
12880411V125Dq11_mvitamin D active form serum level QTL 11 (mouse)1578897881104073951Mouse
10402490Dipa5_mdrug induced psychomotor activation 5 (mouse)Not determined1579163411104073951Mouse
4141897Imrfq2_mimmune response to Factor IX QTL 2 (mouse)Not determined79908940104073951Mouse
1301284Cosz3_mcocaine seizure 3 (mouse)Not determined1580313634104073951Mouse
4141902Cia37_mcollagen induced arthritis 37 (mouse)Not determined1580884933104073951Mouse
1300974Pgia9_mproteoglycan induced arthritis 9 (mouse)Not determined1580884933104073951Mouse
4141511Gdcr1_mglycerolphosphate dehydrogenase regulator 1 (mouse)Not determined82615474104073951Mouse
11530037Sluc34a_msusceptibility to lung cancer 34a (mouse)1585896437104073951Mouse
11530038Sluc34b_msusceptibility to lung cancer 34b (mouse)1585896437104073951Mouse
1357614Bmca_mbile mucin accumulation (mouse)Not determined1585896437104073951Mouse
1301918Skull22_mskull morphology 22 (mouse)Not determined1585901546104073951Mouse
4141581Dshv1_mdorsal hippocampal volume 1 (mouse)Not determined92788640103425899Mouse
14700689Carg5_mCandida albicans resistance gene 5 (mouse)1597697881103008427Mouse
11528547Sluc34_msusceptibility to lung cancer 34 (mouse)1597884933102896555Mouse

Markers in Region
Olfr281  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381598,456,435 - 98,456,953UniSTSGRCm38
MGSCv371598,286,866 - 98,287,384UniSTSGRCm37
Celera15100,611,243 - 100,611,761UniSTS
Cytogenetic Map15F3UniSTS
cM Map15 UniSTS
UniSTS:491600  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381598,456,285 - 98,457,343UniSTSGRCm38
MGSCv371598,286,716 - 98,287,774UniSTSGRCm37
Celera15100,611,093 - 100,612,151UniSTS
Cytogenetic Map15F3UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000109163   ⟹   ENSMUSP00000104791
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1598,354,166 - 98,355,223 (+)Ensembl
GRCm38.p6 Ensembl1598,456,285 - 98,457,342 (+)Ensembl
RefSeq Acc Id: ENSMUST00000217517   ⟹   ENSMUSP00000150530
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1598,350,469 - 98,358,276 (+)Ensembl
GRCm38.p6 Ensembl1598,452,588 - 98,460,395 (+)Ensembl
RefSeq Acc Id: NM_146280   ⟹   NP_666392
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391598,354,193 - 98,355,128 (+)NCBI
GRCm381598,456,312 - 98,457,247 (+)ENTREZGENE
MGSCv371598,286,743 - 98,287,678 (+)RGD
Celera15100,611,120 - 100,612,055 (+)RGD
cM Map15 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_666392   ⟸   NM_146280
- UniProtKB: Q8VET6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000150530   ⟸   ENSMUST00000217517
RefSeq Acc Id: ENSMUSP00000104791   ⟸   ENSMUST00000109163
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VET6-F1-model_v2 AlphaFold Q8VET6 1-311 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3030115 AgrOrtholog
Ensembl Genes ENSMUSG00000032987 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000109163 ENTREZGENE
  ENSMUST00000109163.4 UniProtKB/TrEMBL
  ENSMUST00000217517.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report mmu:258277 UniProtKB/TrEMBL
MGD MGI:3030115 ENTREZGENE
NCBI Gene 258277 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or8s8 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt Q8VET6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-24 Or8s8  olfactory receptor family 8 subfamily S member 8  Olfr281  olfactory receptor 281  Symbol and/or name change 5135510 APPROVED