Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Psd | Mouse | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of PSD mRNA | CTD | PMID:22206623 | Psd | Mouse | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of PSD mRNA | CTD | PMID:22206623 | Psd | Mouse | 17beta-estradiol | increases expression | ISO | Psd (Rattus norvegicus) | 6480464 | Estradiol results in increased expression of PSD mRNA | CTD | PMID:20068009 | Psd | Mouse | 17beta-estradiol | multiple interactions | ISO | PSD (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of PSD mRNA | CTD | PMID:30165855 | Psd | Mouse | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | EXP | | 6480464 | [2 more ... | CTD | PMID:25510870 | Psd | Mouse | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | EXP | | 6480464 | [2 more ... | CTD | PMID:25510870 | Psd | Mouse | 2,2',5,5'-tetrachlorobiphenyl | decreases expression | ISO | PSD (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:36804509 | Psd | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Psd (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PSD mRNA | CTD | PMID:33387578 | Psd | Mouse | 4,4'-sulfonyldiphenol | decreases methylation | EXP | | 6480464 | bisphenol S results in decreased methylation of PSD exon and bisphenol S results in decreased methylation of PSD promoter | CTD | PMID:33297965 | Psd | Mouse | 6-propyl-2-thiouracil | increases expression | ISO | Psd (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of PSD mRNA | CTD | PMID:30047161 | Psd | Mouse | acetylsalicylic acid | increases expression | ISO | PSD (Homo sapiens) | 6480464 | Aspirin results in increased expression of PSD mRNA | CTD | PMID:11906190 | Psd | Mouse | aflatoxin B1 | increases methylation | ISO | PSD (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of PSD intron | CTD | PMID:30157460 | Psd | Mouse | amitrole | decreases expression | ISO | Psd (Rattus norvegicus) | 6480464 | Amitrole results in decreased expression of PSD mRNA | CTD | PMID:38685447 | Psd | Mouse | amitrole | increases expression | ISO | Psd (Rattus norvegicus) | 6480464 | Amitrole results in increased expression of PSD mRNA | CTD | PMID:30047161 | Psd | Mouse | ammonium chloride | affects expression | ISO | Psd (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of PSD mRNA | CTD | PMID:16483693 | Psd | Mouse | benzo[a]pyrene | decreases expression | ISO | Psd (Rattus norvegicus) | 6480464 | Benzo(a)pyrene results in decreased expression of PSD mRNA | CTD | PMID:21839799 | Psd | Mouse | benzo[a]pyrene | decreases expression | ISO | PSD (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of PSD mRNA | CTD | PMID:32234424 | Psd | Mouse | benzo[a]pyrene | increases methylation | ISO | PSD (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of PSD 3' UTR | CTD | PMID:27901495 | Psd | Mouse | benzo[a]pyrene | affects methylation | ISO | PSD (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of PSD 5' UTR and Benzo(a)pyrene affects the methylation of PSD intron | CTD | PMID:27901495 and PMID:30157460 | Psd | Mouse | bisphenol A | affects expression | ISO | Psd (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of PSD mRNA | CTD | PMID:25181051 | Psd | Mouse | bisphenol A | decreases expression | ISO | Psd (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of PSD mRNA | CTD | PMID:30816183 | Psd | Mouse | bisphenol F | decreases expression | EXP | | 6480464 | bisphenol F results in decreased expression of PSD mRNA | CTD | PMID:38685157 | Psd | Mouse | buta-1,3-diene | decreases expression | EXP | | 6480464 | 1 and 3-butadiene results in decreased expression of PSD mRNA | CTD | PMID:29038090 | Psd | Mouse | chlorohydrocarbon | multiple interactions | ISO | Psd (Rattus norvegicus) | 6480464 | [Hydrocarbons and Chlorinated co-treated with Polychlorinated Biphenyls co-treated with methylmercuric chloride] results in decreased expression of PSD mRNA | CTD | PMID:30744511 | Psd | Mouse | copper(II) sulfate | increases expression | ISO | PSD (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of PSD mRNA | CTD | PMID:19549813 | Psd | Mouse | Cuprizon | decreases expression | ISO | Psd (Rattus norvegicus) | 6480464 | Cuprizone results in decreased expression of PSD mRNA | CTD | PMID:26577399 | Psd | Mouse | diazinon | increases methylation | ISO | PSD (Homo sapiens) | 6480464 | Diazinon results in increased methylation of PSD gene | CTD | PMID:22964155 | Psd | Mouse | doxorubicin | increases expression | ISO | PSD (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of PSD mRNA | CTD | PMID:29803840 | Psd | Mouse | ethanol | increases expression | EXP | | 6480464 | Ethanol results in increased expression of PSD mRNA | CTD | PMID:30319688 | Psd | Mouse | ethanol | multiple interactions | EXP | | 6480464 | Ethanol affects the expression of and affects the splicing of PSD mRNA | CTD | PMID:30319688 | Psd | Mouse | folic acid | decreases expression | ISO | PSD (Homo sapiens) | 6480464 | Folic Acid results in decreased expression of PSD mRNA | CTD | PMID:21867686 | Psd | Mouse | folic acid | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of PSD mRNA | CTD | PMID:22206623 | Psd | Mouse | FR900359 | increases phosphorylation | ISO | PSD (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of PSD protein | CTD | PMID:37730182 | Psd | Mouse | gentamycin | increases expression | ISO | Psd (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of PSD mRNA | CTD | PMID:33387578 | Psd | Mouse | lead(0) | affects expression | ISO | PSD (Homo sapiens) | 6480464 | Lead affects the expression of PSD mRNA | CTD | PMID:28903495 | Psd | Mouse | methimazole | decreases expression | ISO | Psd (Rattus norvegicus) | 6480464 | Methimazole results in decreased expression of PSD mRNA | CTD | PMID:38685447 | Psd | Mouse | methimazole | increases expression | ISO | Psd (Rattus norvegicus) | 6480464 | Methimazole results in increased expression of PSD mRNA | CTD | PMID:30047161 | Psd | Mouse | methylmercury chloride | multiple interactions | ISO | Psd (Rattus norvegicus) | 6480464 | [Hydrocarbons and Chlorinated co-treated with Polychlorinated Biphenyls co-treated with methylmercuric chloride] results in decreased expression of PSD mRNA | CTD | PMID:30744511 | Psd | Mouse | N-methyl-4-phenylpyridinium | increases expression | EXP | | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of PSD mRNA | CTD | PMID:22776087 | Psd | Mouse | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of PSD mRNA | CTD | PMID:17562736 | Psd | Mouse | paracetamol | increases expression | ISO | Psd (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of PSD mRNA | CTD | PMID:33387578 | Psd | Mouse | PCB138 | multiple interactions | EXP | | 6480464 | [2 more ... | CTD | PMID:25510870 | Psd | Mouse | resveratrol | multiple interactions | ISO | PSD (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of PSD mRNA | CTD | PMID:23557933 | Psd | Mouse | sodium arsenite | affects methylation | ISO | PSD (Homo sapiens) | 6480464 | sodium arsenite affects the methylation of PSD gene | CTD | PMID:28589171 | Psd | Mouse | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of PSD mRNA | CTD | PMID:37682722 | Psd | Mouse | sulfadimethoxine | increases expression | ISO | Psd (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in increased expression of PSD mRNA | CTD | PMID:30047161 | Psd | Mouse | Tesaglitazar | decreases expression | ISO | Psd (Rattus norvegicus) | 6480464 | tesaglitazar results in decreased expression of PSD mRNA | CTD | PMID:21515302 | Psd | Mouse | thioacetamide | increases expression | ISO | Psd (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of PSD mRNA | CTD | PMID:34492290 | Psd | Mouse | titanium dioxide | increases expression | EXP | | 6480464 | titanium dioxide results in increased expression of PSD mRNA | CTD | PMID:23557971 | Psd | Mouse | titanium dioxide | increases methylation | EXP | | 6480464 | titanium dioxide results in increased methylation of PSD gene | CTD | PMID:35295148 | Psd | Mouse | trichloroethene | increases expression | ISO | Psd (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of PSD mRNA | CTD | PMID:33387578 | Psd | Mouse | triclosan | increases expression | ISO | PSD (Homo sapiens) | 6480464 | Triclosan results in increased expression of PSD mRNA | CTD | PMID:30510588 | Psd | Mouse | triphenyl phosphate | affects expression | ISO | PSD (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of PSD mRNA | CTD | PMID:37042841 | Psd | Mouse | triptonide | increases expression | EXP | | 6480464 | triptonide results in increased expression of PSD mRNA | CTD | PMID:33045310 | Psd | Mouse | troglitazone | decreases expression | EXP | | 6480464 | troglitazone results in decreased expression of PSD mRNA | CTD | PMID:17569031 | Psd | Mouse | troglitazone | decreases expression | ISO | Psd (Rattus norvegicus) | 6480464 | troglitazone results in decreased expression of PSD mRNA | CTD | PMID:21515302 | Psd | Mouse | trovafloxacin | increases expression | EXP | | 6480464 | trovafloxacin results in 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Gene Ontology Annotations Click to see Annotation Detail View
Biological Process
Cellular Component
Molecular Function
Molecular Pathway Annotations Click to see Annotation Detail View
Imported Annotations - KEGG (archival)
Phenotype Annotations Click to see Annotation Detail View
Mammalian Phenotype
Disease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Biological Process
Cellular Component
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Molecular Function
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Phenotype Annotations
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References
References - curated
| # | Reference Title | Reference Citation |
| 1. | Functional annotation of a full-length mouse cDNA collection. | Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90. |
| 2. | MGDs mouse GO annotations | MGD data from the GO Consortium |
| 3. | Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. | Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73. |
| 4. | KEGG Annotation Import Pipeline | Pipeline to import KEGG annotations from KEGG into RGD |
| 5. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 6. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Additional References at PubMed
| PMID:8889548 | PMID:9417912 | PMID:10349636 | PMID:11042159 | PMID:11076861 | PMID:11247667 | PMID:12477932 | PMID:14610273 | PMID:15540117 | PMID:16141072 | PMID:16141073 | PMID:16707115 |
| PMID:17298598 | PMID:18708035 | PMID:19085064 | PMID:19494129 | PMID:21267068 | PMID:21677750 | PMID:24261326 | PMID:24952961 | PMID:24979773 | PMID:26930384 | PMID:30674481 | PMID:31718774 |
| PMID:32059926 | PMID:32325033 | PMID:34321999 | PMID:38355793 | PMID:38725127 | PMID:39126836 |
Genomics
Comparative Map Data
| Psd (Mus musculus - house mouse) |
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| PSD (Homo sapiens - human) |
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| Psd (Rattus norvegicus - Norway rat) |
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| Psd (Chinchilla lanigera - long-tailed chinchilla) |
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| PSD (Pan paniscus - bonobo/pygmy chimpanzee) |
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| PSD (Canis lupus familiaris - dog) |
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| Psd (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| PSD (Sus scrofa - pig) |
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| PSD (Chlorocebus sabaeus - green monkey) |
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| Psd (Heterocephalus glaber - naked mole-rat) |
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Variants
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Variants in Psd
427 total Variants 
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