Wdr48 (WD repeat domain 48) - Rat Genome Database
Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Wdr48 (WD repeat domain 48) Mus musculus
Analyze
Symbol: Wdr48
Name: WD repeat domain 48
RGD ID: 1550376
MGI Page MGI
Description: Predicted to have ubiquitin binding activity. Involved in several processes, including animal organ development; double-strand break repair via homologous recombination; and regulation of protein monoubiquitination. Predicted to localize to nucleus. Is expressed in femur. Orthologous to human WDR48 (WD repeat domain 48); INTERACTS WITH 2,4,6-trinitrobenzenesulfonic acid; 3,4-methylenedioxymethamphetamine; paracetamol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 8430408H12Rik; mKIAA1449; Uaf; Uaf1; USP1-associated factor 1; WD repeat-containing protein 48
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399119,723,943 - 119,755,652 (+)NCBIGRCm39mm39
GRCm389119,894,895 - 119,926,586 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9119,894,878 - 119,926,587 (+)EnsemblGRCm38mm10GRCm38
MGSCv379119,804,013 - 119,835,697 (+)NCBIGRCm37mm9NCBIm37
MGSCv369119,743,593 - 119,775,277 (+)NCBImm8
Celera9120,362,077 - 120,393,799 (+)NCBICelera
Cytogenetic Map9F4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12520002   PMID:12693553   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073  
PMID:16944949   PMID:21267068   PMID:21873635   PMID:21925315   PMID:24001775   PMID:26496610   PMID:29138248   PMID:30196744   PMID:31666509   PMID:32325033   PMID:33247121  


Genomics

Comparative Map Data
Wdr48
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399119,723,943 - 119,755,652 (+)NCBIGRCm39mm39
GRCm389119,894,895 - 119,926,586 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9119,894,878 - 119,926,587 (+)EnsemblGRCm38mm10GRCm38
MGSCv379119,804,013 - 119,835,697 (+)NCBIGRCm37mm9NCBIm37
MGSCv369119,743,593 - 119,775,277 (+)NCBImm8
Celera9120,362,077 - 120,393,799 (+)NCBICelera
Cytogenetic Map9F4NCBI
WDR48
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl339,052,013 - 39,096,671 (+)EnsemblGRCh38hg38GRCh38
GRCh38339,052,002 - 39,096,666 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37339,093,477 - 39,138,155 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36339,068,511 - 39,112,886 (+)NCBINCBI36hg18NCBI36
Build 34339,068,510 - 39,112,883NCBI
Celera339,033,745 - 39,078,385 (+)NCBI
Cytogenetic Map3p22.2NCBI
HuRef339,135,626 - 39,179,803 (+)NCBIHuRef
CHM1_1339,044,543 - 39,089,235 (+)NCBICHM1_1
Wdr48
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08128,577,080 - 128,610,287 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8128,577,080 - 128,610,287 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08127,778,763 - 127,811,970 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48124,850,235 - 124,883,442 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18124,869,881 - 124,902,301 (+)NCBI
Celera8118,769,024 - 118,802,212 (+)NCBICelera
Cytogenetic Map8q32NCBI
Wdr48
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542724,873,616 - 24,917,691 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542724,873,616 - 24,917,691 (-)NCBIChiLan1.0ChiLan1.0
WDR48
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1339,228,920 - 39,273,300 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl339,228,920 - 39,273,300 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0338,948,440 - 38,992,872 (+)NCBIMhudiblu_PPA_v0panPan3
WDR48
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl238,715,700 - 8,764,678 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1238,716,598 - 8,766,242 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Wdr48
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493647328,307,913 - 28,351,727 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WDR48
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1323,735,584 - 23,786,309 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11323,735,566 - 23,786,312 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21325,995,433 - 26,045,850 (+)NCBISscrofa10.2Sscrofa10.2susScr3
WDR48
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.115319,589 - 366,265 (-)NCBI
ChlSab1.1 Ensembl15319,810 - 366,246 (-)Ensembl
Wdr48
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247311,884,660 - 1,934,818 (-)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63332429120362868Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63332429120362868Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963332429120362868Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986230401120230530Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986239845120289624Mouse
11251716Siim2_mstress induced immobility 2 (mouse)986748483120748483Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987800000121800000Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989284925123284925Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989412277123412396Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989563342123563342Mouse
12910770Splic1_mspleen iron content 1 (mouse)991413879124595110Mouse
12910772Lvic6_mliver iron content 6 (mouse)991413879124595110Mouse
12910773Splic3_mspleen iron content 3 (mouse)991413879124595110Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991641084124595110Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991641084124595110Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991641084124595110Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991641084124595110Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991641084124595110Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991641084124595110Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991683173124595110Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991683173124595110Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991683173124595110Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993762590124595110Mouse
1301484Bwq6_mbody weight (mouse)Not determined993762590124595110Mouse
14746992Manh67_mmandible shape 67 (mouse)994036768124595110Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996917590124595110Mouse
1301297Lcho1_mliver cholesterol 1 (mouse)Not determined9101060861124595110Mouse
1357627Tgq2_mtriglyceride QTL 2 (mouse)Not determined9102000187124595110Mouse
1357648Obq18_mobesity QTL 18 (mouse)Not determined9102000187124595110Mouse
1301789Pbwg4_mpostnatal body weight growth 4 (mouse)Not determined9103289445124595110Mouse
10412290Pvacm1l_mplasma vascular cell adhesion molecule 1 levels (mouse)Not determined9103289445124595110Mouse
12879896Berr3_mberghei resistance locus 3 (mouse)9103289445124595110Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:653
Count of miRNA genes:424
Interacting mature miRNAs:504
Transcripts:ENSMUST00000036561
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_026236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006512246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004935524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004935525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC124662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK012599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK018396 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK030041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK031244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK033631 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK035273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK035864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK043970 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK122511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK128953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194852 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC006679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC021348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC040795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC048155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC050106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC062967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000036561   ⟹   ENSMUSP00000042509
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9119,894,878 - 119,926,586 (+)Ensembl
RefSeq Acc Id: ENSMUST00000213230
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9119,912,626 - 119,921,973 (+)Ensembl
RefSeq Acc Id: ENSMUST00000214716
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9119,895,157 - 119,904,368 (+)Ensembl
RefSeq Acc Id: ENSMUST00000215167   ⟹   ENSMUSP00000149793
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9119,907,713 - 119,926,238 (+)Ensembl
RefSeq Acc Id: ENSMUST00000215307   ⟹   ENSMUSP00000149478
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9119,894,906 - 119,926,587 (+)Ensembl
RefSeq Acc Id: ENSMUST00000216349
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9119,918,131 - 119,920,624 (+)Ensembl
RefSeq Acc Id: ENSMUST00000217429
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9119,920,540 - 119,924,026 (+)Ensembl
RefSeq Acc Id: ENSMUST00000217472   ⟹   ENSMUSP00000150321
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9119,894,895 - 119,921,958 (+)Ensembl
RefSeq Acc Id: ENSMUST00000217492
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9119,921,298 - 119,922,679 (+)Ensembl
RefSeq Acc Id: ENSMUST00000217555
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9119,913,638 - 119,917,087 (+)Ensembl
RefSeq Acc Id: NM_026236   ⟹   NP_080512
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399119,723,961 - 119,755,645 (+)NCBI
GRCm389119,894,895 - 119,926,579 (+)NCBI
MGSCv379119,804,013 - 119,835,697 (+)RGD
Celera9120,362,077 - 120,393,799 (+)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006512246   ⟹   XP_006512309
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399119,724,176 - 119,755,652 (+)NCBI
GRCm389119,895,138 - 119,926,586 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004935524
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399119,724,176 - 119,755,652 (+)NCBI
RefSeq Acc Id: XR_004935525
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399119,723,943 - 119,755,652 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_080512   ⟸   NM_026236
- UniProtKB: Q8BH57 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006512309   ⟸   XM_006512246
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000150321   ⟸   ENSMUST00000217472
RefSeq Acc Id: ENSMUSP00000042509   ⟸   ENSMUST00000036561
RefSeq Acc Id: ENSMUSP00000149793   ⟸   ENSMUST00000215167
RefSeq Acc Id: ENSMUSP00000149478   ⟸   ENSMUST00000215307
Protein Domains
WD_REPEATS_REGION

Promoters
RGD ID:6845362
Promoter ID:MM_KWN:59149
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:AK132067_GM2449,   NM_026236,   UC009SBL.1,   UC009SBM.1,   UC009SBO.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv369119,803,631 - 119,804,131 (+)MPROMDB
RGD ID:8671204
Promoter ID:EPDNEW_M13633
Type:multiple initiation site
Name:Wdr48_1
Description:Mus musculus WD repeat domain 48 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm389119,894,895 - 119,894,955EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1914811 AgrOrtholog
Ensembl Genes ENSMUSG00000032512 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000042509 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000149478 UniProtKB/Swiss-Prot
  ENSMUSP00000149793 UniProtKB/TrEMBL
  ENSMUSP00000150321 UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000036561 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000215167 UniProtKB/TrEMBL
  ENSMUST00000215307 UniProtKB/Swiss-Prot
  ENSMUST00000217472 UniProtKB/Swiss-Prot
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro G-protein_beta_WD-40_rep UniProtKB/Swiss-Prot
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/Swiss-Prot
  WD40_repeat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WDR48/Bun107 UniProtKB/Swiss-Prot
KEGG Report mmu:67561 UniProtKB/Swiss-Prot
MGD MGI:1914811 ENTREZGENE
NCBI Gene 67561 ENTREZGENE
Pfam DUF3337 UniProtKB/Swiss-Prot
  WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Wdr48 PhenoGen
PRINTS GPROTEINBRPT UniProtKB/Swiss-Prot
PROSITE WD_REPEATS_1 UniProtKB/Swiss-Prot
  WD_REPEATS_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Mm.104789 ENTREZGENE
  Mm.473239 ENTREZGENE
UniProt A0A1L1SS76_MOUSE UniProtKB/TrEMBL
  Q8BH57 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q80TD4 UniProtKB/Swiss-Prot
  Q80XI0 UniProtKB/Swiss-Prot
  Q8BRM0 UniProtKB/Swiss-Prot
  Q8CBK0 UniProtKB/Swiss-Prot
  Q922Z9 UniProtKB/Swiss-Prot
  Q9CRR1 UniProtKB/Swiss-Prot
  Q9CSL0 UniProtKB/Swiss-Prot