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Gene: H2-DMb2 (histocompatibility 2, class II, locus Mb2) Mus musculus
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Symbol: H2-DMb2
Name: histocompatibility 2, class II, locus Mb2
Description: Predicted to have MHC class II protein complex binding activity. Involved in antigen processing and presentation of exogenous peptide antigen via MHC class II and chaperone cofactor-dependent protein refolding. Localizes to the endosome; integral component of membrane; and lysosomal membrane. Orthologous to human HLA-DMB (major histocompatibility complex, class II, DM beta); PARTICIPATES IN allograft rejection pathway; antigen processing and presentation pathway; asthma pathway; INTERACTS WITH 3,4-methylenedioxymethamphetamine; 3-methylcholanthrene; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: H-2Mb2; H2-M beta2; H2-Mb2; MHC class II antigen Mb2
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381734,143,229 - 34,151,553 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371734,282,361 - 34,288,040 (+)NCBIGRCm37mm9NCBIm37
MGSCv361733,756,075 - 33,761,757 (+)NCBImm8
Celera1736,897,453 - 36,903,129 (+)NCBICelera
Cytogenetic Map17 B1NCBI
cM Map1717.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on H2-DMb2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1550373
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.