Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Aph1a (aph1 homolog A, gamma secretase subunit) Mus musculus
Analyze
Symbol: Aph1a
Name: aph1 homolog A, gamma secretase subunit
Description: Exhibits endopeptidase activity. Involved in Notch receptor processing and metanephros development. Predicted to localize to several cellular components, including cytoplasmic vesicle; gamma-secretase complex; and integral component of presynaptic membrane. Is expressed in several structures, including central nervous system; retina; and urinary system. Orthologous to human APH1A (aph-1 homolog A, gamma-secretase subunit).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 6530402N02Rik; anterior pharynx defective 1a homolog; Aph-1; APH-1a; aph-1alpha; gamma-secretase subunit APH-1A; MGC36389; MGC7221
Orthologs:
Homo sapiens (human) : APH1A (aph-1 homolog A, gamma-secretase subunit)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Aph1a (aph-1 homolog A, gamma secretase subunit)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aph1a (aph-1 homolog A, gamma-secretase subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : APH1A (aph-1 homolog A, gamma-secretase subunit)
Canis lupus familiaris (dog) : APH1A (aph-1 homolog A, gamma-secretase subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aph1a (aph-1 homolog A, gamma-secretase subunit)
Sus scrofa (pig) : APH1A (aph-1 homolog A, gamma-secretase subunit)
Chlorocebus sabaeus (African green monkey) : APH1A (aph-1 homolog A, gamma-secretase subunit)
Heterocephalus glaber (naked mole-rat) : Aph1a (aph-1 homolog A, gamma-secretase subunit)
more info ...
Related Pseudogenes: Gm15429  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl395,893,969 - 95,898,288 (+)EnsemblGRCm38mm10GRCm38
GRCm38395,893,921 - 95,898,592 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37395,697,919 - 95,702,226 (+)NCBIGRCm37mm9NCBIm37
MGSCv36395,979,401 - 95,983,708 (+)NCBImm8
Celera397,327,550 - 97,331,856 (+)NCBICelera
Cytogenetic Map3F2.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Aph1a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1550286
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.