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Gene: Cd2ap (CD2-associated protein) Mus musculus
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Symbol: Cd2ap
Name: CD2-associated protein
Description: Predicted to have several functions, including SH3 domain binding activity; beta-catenin binding activity; and protein C-terminus binding activity. Involved in negative regulation of transforming growth factor beta1 production; positive regulation of protein localization to nucleus; and regulation of actin cytoskeleton reorganization. Localizes to the cell-cell junction; cytoplasm; and plasma membrane. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis. Is expressed in several structures, including alimentary system; blastocyst; early embryo; genitourinary system; and hemolymphoid system gland. Orthologous to human CD2AP (CD2 associated protein).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AL024079; C78928; mesenchyme to epithelium transition protein, SH3 domains; mesenchyme-to-epithelium transition protein with SH3 domains 1; METS-1; Mets1; SH3 domain-containing adapter protein; SH3 domain-containing adaptor protein METS-1
Orthologs:
Homo sapiens (human) : CD2AP (CD2 associated protein)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cd2ap (CD2-associated protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd2ap (CD2 associated protein)
Pan paniscus (bonobo/pygmy chimpanzee) : CD2AP (CD2 associated protein)
Canis lupus familiaris (dog) : CD2AP (CD2 associated protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd2ap (CD2 associated protein)
Sus scrofa (pig) : CD2AP (CD2 associated protein)
more info ...
Related Pseudogenes: Gm6475   Gm7529  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381742,748,887 - 42,876,707 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371742,929,900 - 43,013,373 (-)NCBIGRCm37mm9NCBIm37
MGSCv361742,256,435 - 42,352,155 (-)NCBImm8
Celera1746,201,889 - 46,261,450 (-)NCBICelera
Cytogenetic Map17 B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cd2ap
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1550249
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.