Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Akr1b8 (aldo-keto reductase family 1, member B8) Mus musculus
Symbol: Akr1b8
Name: aldo-keto reductase family 1, member B8
Description: Predicted to have oxidoreductase activity. Predicted to be involved in cellular detoxification of aldehyde; glycoside metabolic process; and terpenoid metabolic process. Predicted to localize to the cytosol and mitochondrion. Is expressed in several structures, including adrenal gland; alimentary system; ear; nervous system; and urinary system. Orthologous to human AKR1B10 (aldo-keto reductase family 1 member B10) and AKR1B15 (aldo-keto reductase family 1 member B15); PARTICIPATES IN fructose and mannose metabolic pathway; galactose metabolic pathway; pentose and glucuronate interconversion pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: aldehyde reductase; aldose reductase-related protein 2; AR; Fgfrp; Fgrp; fibroblast growth factor regulated protein; fibroblast growth factor-regulated protein; FR-1
Related Pseudogenes: Gm18799   Gm18832   Gm18835   Gm5649  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl634,354,119 - 34,368,463 (+)Ensembl
GRCm38634,354,146 - 34,368,461 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37634,304,164 - 34,318,454 (+)NCBIGRCm37mm9NCBIm37
MGSCv36634,284,322 - 34,298,612 (+)NCBImm8
Celera634,351,110 - 34,365,396 (+)NCBICelera
Cytogenetic Map6 B1NCBI
cM Map614.91NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Akr1b8
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1550101
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.