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Gene: Gimap6 (GTPase, IMAP family member 6) Mus musculus

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Symbol:

Gimap6

Name:

GTPase, IMAP family member 6

RGD ID:

1550092

MGI Page

MGI

Description:

Predicted to enable GTP binding activity. Acts upstream of or within several processes, including autophagy; cell redox homeostasis; and defense response to other organism. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and hemolymphoid system. Orthologous to human GIMAP6 (GTPase, IMAP family member 6).

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

4833419H03Rik; FLJ00102; GTPase IMAP family member 6; I; IAN-6; Ian6; immune associated nucleotide 6; immune-associated nucleotide 6; immunity-associated nucleotide 6 protein; mFLJ00102; MGC41522; mIAN6

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GIMAP6 (GTPase, IMAP family member 6)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OrthoDB, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Gimap6 (GTPase, IMAP family member 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gimap6 (GTPase, IMAP family member 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GIMAP6 (GTPase, IMAP family member 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GIMAP6 (GTPase, IMAP family member 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gimap6 (GTPase, IMAP family member 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GIMAP6 (GTPase, IMAP family member 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GIMAP6 (GTPase, IMAP family member 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gimap6 (GTPase, IMAP family member 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Gimap6 (GTPase, IMAP family member 6)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	GIMAP6 (GTPase, IMAP family member 6)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	zgc:113625	Alliance	DIOPT (Ensembl Compara\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	si:dkey-73p2.1	Alliance	DIOPT (Ensembl Compara\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	si:dkey-175d9.2	Alliance	DIOPT (Ensembl Compara\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	zgc:101806	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER)
Danio rerio (zebrafish):	zgc:172091	Alliance	DIOPT (Ensembl Compara\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	si:ch211-254c8.3	Alliance	DIOPT (Ensembl Compara\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	si:dkey-1c7.3	Alliance	DIOPT (Ensembl Compara\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	zgc:172131	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	48,678,517 - 48,685,178 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	48,678,516 - 48,685,159 (-)	Ensembl		GRCm39 Ensembl
GRCm38	6	48,701,583 - 48,708,244 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	48,701,582 - 48,708,225 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	48,651,582 - 48,658,243 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	48,631,169 - 48,637,830 (-)	NCBI		MGSCv36	mm8
Celera	6	49,212,428 - 49,219,095 (-)	NCBI		Celera
Cytogenetic Map	6	B2.3	NCBI
cM Map	6	23.67	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

long QT syndrome (ISO)

primary immunodeficiency disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (EXP)

1-Hydroxypyrene (ISO)

17beta-estradiol (ISO)

17beta-estradiol 3-benzoate (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

4,4'-sulfonyldiphenol (EXP)

4-hydroxyphenyl retinamide (EXP)

acrylamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (ISO)

amphetamine (ISO)

arsenous acid (ISO)

asbestos (ISO)

benzo[a]pyrene (EXP)

benzo[b]fluoranthene (EXP)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

captan (EXP)

chlorpyrifos (EXP)

chromium(6+) (EXP)

cisplatin (ISO)

cobalt dichloride (ISO)

diarsenic trioxide (ISO)

Dibutyl phosphate (ISO)

dimethylarsinic acid (EXP)

diquat (EXP)

doxorubicin (ISO)

fenthion (EXP)

flutamide (ISO)

folic acid (EXP)

folpet (EXP)

gentamycin (ISO)

lipopolysaccharide (ISO)

methidathion (EXP)

methylarsonic acid (EXP)

nickel atom (ISO)

okadaic acid (EXP)

ozone (EXP)

paracetamol (EXP,ISO)

phenobarbital (EXP)

quercitrin (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

silver atom (EXP)

silver(0) (EXP)

sodium arsenate (EXP)

sodium arsenite (EXP)

sodium dichromate (EXP)

testosterone (ISO)

triphenyl phosphate (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

autophagy (IMP)

biological_process (ND)

cell redox homeostasis (IMP)

defense response to bacterium (IMP)

immune response (IMP)

kidney development (IMP)

lipid metabolic process (IMP)

response to type II interferon (IMP)

Cellular Component

cytosol (IBA,ISO,ISS)

Molecular Function

GTP binding (IEA)

molecular_function (ND)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal autophagy (IAGP)

abnormal leukocyte morphology (IAGP)

abnormal mitochondrial morphology (IAGP)

abnormal mitophagy (IAGP)

abnormal sleep behavior (IEA)

abnormal T cell physiology (IAGP)

decreased B cell number (IAGP)

decreased CD4-negative NK T cell number (IEA)

decreased circulating amylase level (IEA)

decreased circulating glucose level (IEA)

decreased circulating iron level (IEA)

decreased lean body mass (IEA)

decreased mean corpuscular hemoglobin (IEA)

decreased mean corpuscular volume (IEA)

decreased memory-marker CD4-negative NK T cell number (IEA)

decreased T cell number (IAGP)

impaired glucose tolerance (IEA)

increased B cell number (IAGP)

increased blood urea nitrogen level (IEA)

increased circulating alkaline phosphatase level (IEA)

increased circulating calcium level (IEA)

increased circulating chloride level (IEA)

increased circulating cholesterol level (IEA)

increased circulating HDL cholesterol level (IEA)

increased circulating sodium level (IEA)

increased fasting circulating glucose level (IEA)

increased heart weight (IEA)

increased memory-marker CD4-negative NK T cell number (IEA)

increased monocyte cell number (IEA)

increased T cell apoptosis (IAGP)

increased total body fat amount (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Functional annotation of a full-length mouse cDNA collection.	Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2.	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:10349636	PMID:10834841	PMID:11042159	PMID:11076861	PMID:12477932	PMID:15474311	PMID:16141072	PMID:16141073	PMID:21677750	PMID:21873635	PMID:24003143	PMID:24194600
PMID:27626380	PMID:29718959	PMID:30973865	PMID:35551368	PMID:38355793

Genomics

Comparative Map Data

Gimap6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	48,678,517 - 48,685,178 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	48,678,516 - 48,685,159 (-)	Ensembl		GRCm39 Ensembl
GRCm38	6	48,701,583 - 48,708,244 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	48,701,582 - 48,708,225 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	48,651,582 - 48,658,243 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	48,631,169 - 48,637,830 (-)	NCBI		MGSCv36	mm8
Celera	6	49,212,428 - 49,219,095 (-)	NCBI		Celera
Cytogenetic Map	6	B2.3	NCBI
cM Map	6	23.67	NCBI

GIMAP6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	150,625,375 - 150,632,385 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	150,625,375 - 150,632,648 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	150,322,463 - 150,329,473 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	149,953,396 - 149,960,374 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	7	144,879,549 - 144,886,767 (-)	NCBI		Celera
Cytogenetic Map	7	q36.1	NCBI
HuRef	7	144,134,104 - 144,141,307 (-)	NCBI		HuRef
CHM1_1	7	150,330,849 - 150,338,123 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	7	151,798,261 - 151,805,271 (-)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	149,651,755 - 149,659,029 (-)	NCBI

Gimap6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	78,984,597 - 78,990,006 (-)	NCBI		GRCr8
mRatBN7.2	4	77,653,703 - 77,659,112 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	77,652,610 - 77,659,116 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	82,861,284 - 82,866,692 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	78,636,779 - 78,642,187 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	77,077,064 - 77,082,472 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	78,337,528 - 78,342,937 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	78,336,423 - 78,342,863 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	143,025,686 - 143,031,095 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	76,794,903 - 76,800,312 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	4	77,069,939 - 77,076,351 (-)	NCBI
Celera	4	72,591,060 - 72,596,469 (-)	NCBI		Celera
Cytogenetic Map	4	q24	NCBI

Gimap6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955491	5,125,041 - 5,130,182 (-)	NCBI	ChiLan1.0	ChiLan1.0

GIMAP6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	187,040,958 - 187,048,104 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	39,051,677 - 39,058,373 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	142,207,877 - 142,215,023 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	154,361,325 - 154,368,602 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	154,361,325 - 154,366,089 (-)	Ensembl	panpan1.1		panPan2

GIMAP6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	14,846,943 - 14,852,772 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	15,454,528 - 15,460,655 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	16,561,491 - 16,567,619 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	16	16,561,499 - 16,567,514 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	16	14,940,890 - 14,947,012 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	16	15,523,134 - 15,528,397 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	15,572,487 - 15,578,655 (-)	NCBI		UU_Cfam_GSD_1.0

Gimap6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	6,756,532 - 6,760,486 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936527	6,142,943 - 6,145,277 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GIMAP6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	18	6,419,033 - 6,420,959 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	18	6,414,771 - 6,420,765 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	18	6,629,965 - 6,635,930 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GIMAP6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	118,804,930 - 118,812,155 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	21	118,804,929 - 118,812,073 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666072	14,777,583 - 14,784,808 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gimap6
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624800	5,932,402 - 5,937,787 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624800	5,932,521 - 5,937,656 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Gimap6
341 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	1389
Count of miRNA genes:	666
Interacting mature miRNAs:	794
Transcripts:	ENSMUST00000053661, ENSMUST00000119315, ENSMUST00000126422, ENSMUST00000132725
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
4142271	Egq8_m	early growth QTL 8 (mouse)			Not determined			4503823	96633110	Mouse
1301266	Lmr4_m	leishmaniasis resistance 4 (mouse)			Not determined		6	42093358	76093500	Mouse
4140989	Spqq2_m	sperm quality QTL 2 (mouse)			Not determined			17711598	51711719	Mouse
12910785	Pwgrq16_m	post-weaning growth rate QTL 16 (mouse)					6	43803747	77788506	Mouse
11252142	Mom12_m	Modifier of Min 12 (mouse)					6	33872261	67872400	Mouse
12910798	Pwgrq5_m	pre-weaning growth rate QTL 5 (mouse)					6	43803747	77788506	Mouse
1300767	Aliq4_m	acute lung injury QTL 4 (mouse)			Not determined		6	36273332	70273435	Mouse
4142259	Tabw2_m	tally ho associated body weight 2 (mouse)			Not determined			46912919	136400690	Mouse
4142126	W3q3_m	weight 3 weeks QTL 3 (mouse)			Not determined			4503823	96633110	Mouse
14746995	Manh60_m	mandible shape 60 (mouse)					6	37202662	71202662	Mouse
12910807	Pwbwq11_m	post-weaning body weight QTL 11 (mouse)					6	43803747	77788506	Mouse
1357442	Dbts1_m	diabetes 1 (mouse)			Not determined		6	18234147	73364675	Mouse
12910802	Pwbwq12_m	post-weaning body weight QTL 12 (mouse)					6	43803747	77788506	Mouse
4141094	Hrtr1_m	heart rate 1 (mouse)			Not determined			36741463	70741463	Mouse
1300618	Pgia19_m	proteoglycan induced arthritis 19 (mouse)			Not determined		6	45290993	87403016	Mouse
4141988	Obrq3_m	obesity resistance QTL 3 (mouse)			Not determined			28290993	62291115	Mouse
12910809	Pwbwq10_m	post-weaning body weight QTL 10 (mouse)					6	43803747	77788506	Mouse
12910820	Ogrq3_m	overall growth rate QTL 3 (mouse)					6	43803747	77788506	Mouse
26884414	Bzwq12_m	bi-zygomatic width QTL 12, 16 week (mouse)					6	3400000	139076998	Mouse
4142361	W10q11_m	weight 10 weeks QTL 11 (mouse)			Not determined			4503823	96633110	Mouse
4142232	W6q4_m	weight 6 weeks QTL 4 (mouse)			Not determined			4503823	96633110	Mouse
12904940	Edlmmq5_m	extensor digitorum longus muscle mass QTL 5 (mouse)					6	19616346	53616346	Mouse
12904943	Tammq4_m	tibialis anterior muscle mass QTL 4 (mouse)					6	19616346	53616346	Mouse
10412213	Sxbq2_m	SGC/Knj cross B6 QTL 2 (mouse)			Not determined		6	19912685	71299759	Mouse
4141454	Obrq4_m	obesity resistance QTL 4 (mouse)			Not determined			31703499	65703611	Mouse
12904952	Gmmq4_m	gastrocnemius muscle mass QTL 4 (mouse)					6	19616346	53616346	Mouse
1357481	Aaj2_m	anxiety in A/J 2 (mouse)			Not determined		6	4503823	48703611	Mouse
13208564	Bmiq7_m	body mass index QTL 7 (mouse)					6	24999999	79976983	Mouse
26884441	Sklq3_m	skull length QTL 3, 5 week (mouse)					6	7600000	80576983	Mouse
1357520	Axtq2_m	anxiety QTL 2 (mouse)			Not determined		6	4503823	48703611	Mouse
1301850	Fglu_m	fasting glucose (mouse)			Not determined		6	17711598	51711719	Mouse
1300959	Lxw2_m	lupus BXSB x NZW 2 (mouse)			Not determined		6	33872261	67872400	Mouse
1301724	Pcd4ts1_m	p-glycoprotein positive CD4 T cell subset 1 (mouse)			Not determined		6	17711598	51711719	Mouse
10412107	Desp4_m	despair 4 (mouse)			Not determined		6	20049830	54049830	Mouse
11353841	Bmiq3_m	body mass index QTL 3 (mouse)					6	4503823	48703611	Mouse
1301326	Trbv4c2_m	T cell receptor beta variable 4 (mouse)			Not determined		6	40868230	71356155	Mouse
1300556	Cia6_m	collagen induced arthritis QTL 6 (mouse)			Not determined		6	4464884	87403016	Mouse
1558984	Cplaq9_m	circadian period of locomotor activity 9 (mouse)			Not determined		6	38646560	92584431	Mouse
10412157	Fl1n_m	fatty liver 1 in NSY (mouse)			Not determined		6	45290993	128811995	Mouse
25440480	Moaq2_m	modifier of alien QTL 2 (mouse)					6	3050001	117476961	Mouse
4141782	Mrdq5_m	modifier of retinal degeneration QTL 5 (mouse)			Not determined			32827585	78215957	Mouse
12880424	V25Dq4_m	vitamin D inactive form serum level QTL 4 (mouse)					6	41576985	75576985	Mouse
12880425	V25Dq5_m	vitamin D inactive form serum level QTL 5 (mouse)					6	32676980	66676980	Mouse
11040600	Lmr4c_m	leishmaniasis resistance 4c (mouse)					6	42093358	76093500	Mouse
11040601	Lmr4a_m	leishmaniasis resistance 4a (mouse)					6	42093358	76093500	Mouse
14700690	Ccs6_m	colon cancer susceptibility 6 (mouse)					6	23776934	57776934	Mouse
11533915	Mts4_m	mammary tumor susceptibility 4 (mouse)					6	42093358	76093500	Mouse
10043885	Cia6c_m	collagen induced arthritis QTL 6c (mouse)			Not determined		6	44442805	71096451	Mouse
1357539	Bsbob3_m	BSB obesity 3 (mouse)			Not determined		6	36448456	70448576	Mouse
27226726	Tibmd7_m	tibia midshaft diameter 7, 16 week (mouse)					6	17699999	53476985	Mouse

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_153175	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC153894	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF503921	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK030902	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK050328	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK087275	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK160244	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK220304	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC028779	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BU699766	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466597	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000053661 ⟹ ENSMUSP00000059371

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	48,678,516 - 48,685,159 (-)	Ensembl
GRCm38.p6 Ensembl	6	48,701,582 - 48,708,225 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000119315 ⟹ ENSMUSP00000113918

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	48,678,517 - 48,685,147 (-)	Ensembl
GRCm38.p6 Ensembl	6	48,701,583 - 48,708,213 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000126422 ⟹ ENSMUSP00000145325

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	48,680,668 - 48,685,130 (-)	Ensembl
GRCm38.p6 Ensembl	6	48,703,734 - 48,708,196 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000132725

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	48,681,356 - 48,683,170 (-)	Ensembl
GRCm38.p6 Ensembl	6	48,704,422 - 48,706,236 (-)	Ensembl

RefSeq Acc Id:

NM_153175 ⟹ NP_694815

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	6	48,678,517 - 48,685,178 (-)	NCBI
GRCm38	6	48,701,583 - 48,708,244 (-)	ENTREZGENE
MGSCv37	6	48,651,582 - 48,658,243 (-)	RGD
Celera	6	49,212,428 - 49,219,095 (-)	RGD
cM Map	6		ENTREZGENE

Sequence:

show sequence

TCATTTCCTGTTTCTCATTGCACAGCGAGCTGCTATTTTGAAGGACAGTTCTTGAGCTCAGATC
ATATTTTGCCGACAAAATATGGATTGAAAGATGGATTGGCTTTACAGAAAAACACTCGGGTCCA
TCGGCTCATGTTCTATAGAAACTTTTCCCTGGCCATTCTATTCATTCTTTCAGAGAATCTACAT
TTCGACCCCACCAGGAAAGCCAGAAAATTCACCAGAGACCAGTGCTACTGAAGTCGGGGAACAG
AGACCTTCTTGCCTGTCAGCCAGCCCAGTGGTGGAAGAGGAAGAGTGTGAGCACAGACCTGAGA
AGAATCCCACAAGGCAGTGGCCCCTGGACTCTGGACAAGGATTGACAAAAGGTCTGAAGGAGAA
AAAACTCACCCCAAAGAGACTGCAGCTCCTTCTGGTGGGGAAAACAGGAAGCGGGAAAAGTGCA
ACAGGGAACAGCATCCTTGGCAGGCAAGCCTTTGAATCCAAAATCAGCGCTCGACCAGTGACCA
CGACATTCCAGAAAGGGACTAGAGAGTTTGAGGGGAAAGAACTTGAGGTGATCGACACCCCAGA
TATTTTTTCACCTCAGAACCAGCCTGAGGCAACAGCTAAGAAGATCTGTGACCTCTTGGCCTCA
CCAGGGCCCCATGCAGTGCTGCTGGTGATACAGGTAGGCCGGTACACTGCCGAGGACCAGGCGG
TAGCCAGGTGCCTCCAGGAGATCTTTGGAAACACGATCCTGGCTTACACTATTCTGGTGTTCAC
CCGGAAGGAAGACCTGGCTGAGGGCTCCTTAGAAGAATATATTCAAGAGAACAACAATAAGAGC
CTGGATGTTCTGGATGTTGCATGTGAGAGGCGCCACTGTGGCTTCAACAACAAGGCACAAGGGG
ATGAGCAGGAGGCCCAGTTGAAGAAACTTATGGAGGAAGTCGAATTGATCTTGTGGGAAAATGA
GGGCCATTGTTACACCATGGAATTTCCAAATGTTCCCAGCAAGACACTGTAACCAAATAGCAAG
GCCCTGAGGAGGCAACCATTAAAGAGTCCTGGCTGAAAAGGCTGTCCCAGATTCAGATGGCCTC
TGAGAAGCCCTGTAGGTACTGAGGCAGAGGGCATCCATGTGAACCAAGCTGGCCATAAGCAGGA
GTGTCTTAGTCAGTGTTCTATTGCTGTGAAGAGACACCATGACTGTGGCAAATCTTATAAAAGA
AAACATTTAATTGGGGCTTAGCCCATTATCTGGACTATTTAATAGATTGTGTTCTATAACCATG
TTCTAACCATTGACTTACTTCTAAGCCCTTGAGAGACTTTGCTGCAATGGCATATGTACAGTGA
CTAATTCTGAACAGTATATGTCTTTCCTGGGGAGGGGCAGGAGTAGTACCATCTTTTGTGAGCT
AAGTAGAGTTGGATGTATAGGAACAGATTACCAAGCACAAGCAAGTCTTACAACAGAGTCAACA
AGTCTTGCAACAGATAGGCAGGACACAGCAGAGATCCTGAGGAGTCAAATATGAGAGAGCCAAC
CCAGAGCCATCCCCTGTGTGCTGTCTCCCCTGTGCTCCACCATAAGTCCCCAATAAAGCCTTCA
TGTCCCATTGGT

hide sequence

Protein Sequences


Protein RefSeqs	NP_694815	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH28779	(Get FASTA)	NCBI Sequence Viewer
	AAN03835	(Get FASTA)	NCBI Sequence Viewer
	BAD90383	(Get FASTA)	NCBI Sequence Viewer
	BAE35709	(Get FASTA)	NCBI Sequence Viewer
	EDK98564	(Get FASTA)	NCBI Sequence Viewer
	EDK98565	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000059371
	ENSMUSP00000059371.5
	ENSMUSP00000113918.2
	ENSMUSP00000145325.2
GenBank Protein	Q8K349	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_694815 ⟸ NM_153175

- UniProtKB:

Q8K434 (UniProtKB/Swiss-Prot), Q8K349 (UniProtKB/Swiss-Prot), Q5DU66 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MDWLYRKTLGSIGSCSIETFPWPFYSFFQRIYISTPPGKPENSPETSATEVGEQRPSCLSASPV
VEEEECEHRPEKNPTRQWPLDSGQGLTKGLKEKKLTPKRLQLLLVGKTGSGKSATGNSILGRQA
FESKISARPVTTTFQKGTREFEGKELEVIDTPDIFSPQNQPEATAKKICDLLASPGPHAVLLVI
QVGRYTAEDQAVARCLQEIFGNTILAYTILVFTRKEDLAEGSLEEYIQENNNKSLDVLDVACER
RHCGFNNKAQGDEQEAQLKKLMEEVELILWENEGHCYTMEFPNVPSKTL

hide sequence

Ensembl Acc Id:

ENSMUSP00000113918 ⟸ ENSMUST00000119315

Ensembl Acc Id:

ENSMUSP00000059371 ⟸ ENSMUST00000053661

Ensembl Acc Id:

ENSMUSP00000145325 ⟸ ENSMUST00000126422

Protein Domains

AIG1-type G

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8K349-F1-model_v2	AlphaFold	Q8K349	1-305	view protein structure

Promoters

RGD ID:

6839349

Promoter ID:

MM_KWN:45923

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Kidney, Lung, Spleen

Transcripts:

OTTMUST00000066548

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	6	48,655,926 - 48,656,426 (-)	MPROMDB

RGD ID:

6839346

Promoter ID:

MM_KWN:45924

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Kidney, Liver, Lung, Spleen

Transcripts:

OTTMUST00000066545, OTTMUST00000066547, UC009BVN.1

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	6	48,657,949 - 48,658,449 (-)	MPROMDB

RGD ID:

6889630

Promoter ID:

EPDNEW_M8266

Type:

initiation region

Name:

Gimap6_1

Description:

Mus musculus GTPase, IMAP family member 6 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	6	48,708,185 - 48,708,245	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1918876	AgrOrtholog
Ensembl Genes	ENSMUSG00000047867	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000053661	ENTREZGENE
	ENSMUST00000053661.7	UniProtKB/Swiss-Prot
	ENSMUST00000119315.2	UniProtKB/TrEMBL
	ENSMUST00000126422.3	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/Swiss-Prot
InterPro	G_AIG1	UniProtKB/Swiss-Prot
	GIMA/IAN/Toc	UniProtKB/Swiss-Prot
	P-loop_NTPase	UniProtKB/Swiss-Prot
KEGG Report	mmu:231931	UniProtKB/Swiss-Prot
MGD	MGI:1918876	ENTREZGENE
NCBI Gene	Gimap6	ENTREZGENE
PANTHER	GTPASE IMAP FAMILY MEMBER 6	UniProtKB/Swiss-Prot
	PTHR10903	UniProtKB/Swiss-Prot
Pfam	AIG1	UniProtKB/Swiss-Prot
PhenoGen	Gimap6	PhenoGen
PROSITE	G_AIG1	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF52540	UniProtKB/Swiss-Prot
UniProt	A0A0N4SW08_MOUSE	UniProtKB/TrEMBL
	D3Z3H3_MOUSE	UniProtKB/TrEMBL
	GIMA6_MOUSE	UniProtKB/Swiss-Prot
	Q5DU66	ENTREZGENE
	Q8K349	ENTREZGENE
	Q8K434	ENTREZGENE
UniProt Secondary	Q5DU66	UniProtKB/Swiss-Prot
	Q8K434	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2024-08-26	Gimap6	GTPase, IMAP family member 6	4833419H03Rik	RIKEN cDNA 4833419H03 gene	Symbol and/or name updated	27372883	PROVISIONAL
2024-08-21	4833419H03Rik	RIKEN cDNA 4833419H03 gene	Gimap6	GTPase, IMAP family member 6	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Mammalian Phenotype