Popdc2 (popeye domain containing 2) - Rat Genome Database

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Gene: Popdc2 (popeye domain containing 2) Mus musculus
Analyze
Symbol: Popdc2
Name: popeye domain containing 2
RGD ID: 1550026
MGI Page MGI
Description: Enables cAMP binding activity. Acts upstream of or within regulation of heart rate; regulation of membrane potential; and sinoatrial node cell development. Located in membrane. Is expressed in several structures, including gut; heart and pericardium; limb; trunk; and urogenital sinus. Orthologous to human POPDC2 (popeye domain containing 2).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AV006127; P; Pop2; popeye 2; popeye domain-containing protein 2; popeye protein 2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391638,182,523 - 38,198,578 (+)NCBIGRCm39mm39
GRCm39 Ensembl1638,182,571 - 38,198,578 (+)Ensembl
GRCm381638,362,161 - 38,378,216 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1638,362,209 - 38,378,216 (+)EnsemblGRCm38mm10GRCm38
MGSCv371638,362,259 - 38,378,302 (+)NCBIGRCm37mm9NCBIm37
MGSCv361638,281,484 - 38,297,455 (+)NCBImm8
Celera1638,772,441 - 38,788,493 (+)NCBICelera
Cytogenetic Map16B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

Additional References at PubMed
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12477932   PMID:14610273   PMID:16141072   PMID:16141073   PMID:18189275   PMID:19075228   PMID:21267068  
PMID:21873635   PMID:22354168   PMID:24646234   PMID:26411676   PMID:27217161   PMID:32535041  


Genomics

Comparative Map Data
Popdc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391638,182,523 - 38,198,578 (+)NCBIGRCm39mm39
GRCm39 Ensembl1638,182,571 - 38,198,578 (+)Ensembl
GRCm381638,362,161 - 38,378,216 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1638,362,209 - 38,378,216 (+)EnsemblGRCm38mm10GRCm38
MGSCv371638,362,259 - 38,378,302 (+)NCBIGRCm37mm9NCBIm37
MGSCv361638,281,484 - 38,297,455 (+)NCBImm8
Celera1638,772,441 - 38,788,493 (+)NCBICelera
Cytogenetic Map16B3NCBI
POPDC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3119,636,457 - 119,665,324 (-)EnsemblGRCh38hg38GRCh38
GRCh383119,642,056 - 119,660,589 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373119,360,903 - 119,379,436 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363120,843,596 - 120,862,094 (-)NCBINCBI36hg18NCBI36
Build 343120,843,597 - 120,862,094NCBI
Celera3117,769,457 - 117,787,954 (-)NCBI
Cytogenetic Map3q13.33NCBI
HuRef3116,736,572 - 116,755,066 (-)NCBIHuRef
CHM1_13119,324,408 - 119,342,901 (-)NCBICHM1_1
Popdc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21162,351,843 - 62,398,688 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1162,374,759 - 62,390,756 (-)Ensembl
Rnor_6.01164,915,041 - 64,954,704 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1164,936,692 - 64,952,687 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01167,129,306 - 67,151,642 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41164,154,286 - 64,170,282 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11164,211,875 - 64,227,871 (-)NCBI
Celera1161,876,220 - 61,892,242 (-)NCBICelera
Cytogenetic Map11q21NCBI
Popdc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542719,345,226 - 19,367,759 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542719,347,880 - 19,367,759 (-)NCBIChiLan1.0ChiLan1.0
POPDC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13123,673,815 - 123,692,684 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3123,673,815 - 123,692,684 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03116,761,474 - 116,780,369 (-)NCBIMhudiblu_PPA_v0panPan3
POPDC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13323,275,666 - 23,295,413 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3323,276,455 - 23,295,088 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3323,306,245 - 23,325,293 (-)NCBI
ROS_Cfam_1.03323,513,597 - 23,533,028 (-)NCBI
UMICH_Zoey_3.13323,316,273 - 23,335,538 (-)NCBI
UNSW_CanFamBas_1.03323,352,389 - 23,370,898 (-)NCBI
UU_Cfam_GSD_1.03323,921,853 - 23,941,107 (-)NCBI
Popdc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602130,939,491 - 130,958,507 (+)NCBI
SpeTri2.0NW_0049365366,562,583 - 6,582,407 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
POPDC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13140,601,515 - 140,620,789 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113140,601,522 - 140,621,928 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213149,932,130 - 149,951,356 (+)NCBISscrofa10.2Sscrofa10.2susScr3
POPDC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12261,160,174 - 61,178,838 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2261,160,413 - 61,178,414 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666041105,133,456 - 105,151,992 (-)NCBIVero_WHO_p1.0
Popdc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473128,490,489 - 28,521,611 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
Pop2-pending  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381638,373,960 - 38,374,075UniSTSGRCm38
MGSCv371638,374,046 - 38,374,161UniSTSGRCm37
Celera1638,784,229 - 38,784,344UniSTS
Cytogenetic Map16B3UniSTS
cM Map16 UniSTS
AV006127  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381638,377,894 - 38,378,020UniSTSGRCm38
MGSCv371638,377,980 - 38,378,106UniSTSGRCm37
Celera1638,788,171 - 38,788,297UniSTS
Cytogenetic Map16B3UniSTS
Whitehead/MRC_RH16373.37UniSTS
Popdc2   No map positions available.
Popdc2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16B3UniSTS
Popdc2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16B3UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27095908Scvln7_msacral vertebrae length 2, 5 week (mouse)16350000040000000Mouse
27226768Tibl9_mtibia length 9, 5 week (mouse)16350000051600000Mouse
27226785Feml12_mfemur length 12, 5 week (mouse)16350000064800000Mouse
26884432Zlq7_mzygomatic length QTL 7, 10 week (mouse)16400000064800000Mouse
38501069Tip4_mtuberculosis immunophenotype 4, IFN-g level (mouse)16450000044700000Mouse
1301443Mopkd2_mmodifier of polycystic kidney disease progression 2 (mouse)Not determined16482756438827664Mouse
1300656Bgeq15_mbody growth early QTL 15 (mouse)Not determined16595650239956690Mouse
1301945Skl7_mskeletal size (tail length) 7 (mouse)Not determined16595650239956690Mouse
1300987Skull23_mskull morphology 23 (mouse)Not determined16595650239956690Mouse
1300943Skts9_mskin tumor susceptibility 9 (mouse)Not determined16595650239956690Mouse
1357763Lp1_mlymphocyte proliferation 1 (mouse)Not determined16672511565669666Mouse
11251724Ewc6_methanol withdrawal and consumption 6 (mouse)16840730242407302Mouse
26884376Skwq4_mskull length QTL 4, 5 week (mouse)16860000091100000Mouse
10043978Obq35_mobesity QTL 35 (mouse)Not determined161006288144062881Mouse
1301086Lprm5_mlymphoproliferation modifier 5 (mouse)Not determined161203007246030171Mouse
1301841Lrnx9_mlearning-contextual 9 (mouse)Not determined161240654246406653Mouse
10045614Rapop6_mradiation-induced apoptosis 6 (mouse)Not determined161498410348984214Mouse
4142236Pstc4_mperiosteal circumference 4 (mouse)Not determined161570409149704294Mouse
1357517Bwtn1_mbody weight at necropsy 1 (mouse)Not determined162020057985803938Mouse
1300534Bmd15_mbone mineral density 15 (mouse)Not determined162211802156118212Mouse
4141179Ipng3_mimprinted postnatal growth 3 (mouse)Not determined2295650257773713Mouse
1300915Lmr12_mleishmaniasis resistance 12 (mouse)Not determined162897245062972589Mouse
11059559Lmr12a_mleishmaniasis resistance 12a (mouse)162897245062972589Mouse
11059560Lmr12b_mleishmaniasis resistance 12b (mouse)162897245062972589Mouse
11049571Lmr12c_mleishmaniasis resistance 12c (mouse)162897245062972589Mouse
1301070Cypr1_mcytokine production 1 (mouse)Not determined163249243266492570Mouse
4142187Arrd3_mage-related retinal degeneration 3 (mouse)Not determined3270409165669666Mouse
1302096Aod1a_mautoimmune ovarian dysgenesis 1a (mouse)Not determined163562627392776120Mouse
10412263Gvhd6_mgraft-versus host disease 6 (mouse)Not determined163624048745690785Mouse
26884416Bzwq5_mbi-zygomatic width QTL 5, 5 week (mouse)163750000084900000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:945
Count of miRNA genes:423
Interacting mature miRNAs:482
Transcripts:ENSMUST00000023494, ENSMUST00000114739, ENSMUST00000127892, ENSMUST00000141189, ENSMUST00000146342
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000023494   ⟹   ENSMUSP00000023494
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1638,182,571 - 38,198,578 (+)Ensembl
GRCm38.p6 Ensembl1638,362,209 - 38,378,216 (+)Ensembl
RefSeq Acc Id: ENSMUST00000114739   ⟹   ENSMUSP00000110387
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1638,182,607 - 38,198,578 (+)Ensembl
GRCm38.p6 Ensembl1638,362,245 - 38,378,216 (+)Ensembl
RefSeq Acc Id: ENSMUST00000127892
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1638,189,788 - 38,198,125 (+)Ensembl
GRCm38.p6 Ensembl1638,369,426 - 38,377,763 (+)Ensembl
RefSeq Acc Id: ENSMUST00000141189
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1638,189,172 - 38,194,556 (+)Ensembl
GRCm38.p6 Ensembl1638,368,810 - 38,374,194 (+)Ensembl
RefSeq Acc Id: ENSMUST00000146342
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1638,192,360 - 38,194,499 (+)Ensembl
GRCm38.p6 Ensembl1638,371,998 - 38,374,137 (+)Ensembl
RefSeq Acc Id: NM_001081984   ⟹   NP_001075453
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391638,182,552 - 38,198,578 (+)NCBI
GRCm381638,362,190 - 38,378,216 (+)NCBI
MGSCv371638,362,259 - 38,378,302 (+)RGD
Celera1638,772,441 - 38,788,493 (+)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_022318   ⟹   NP_071713
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391638,182,552 - 38,198,578 (+)NCBI
GRCm381638,362,190 - 38,378,216 (+)NCBI
MGSCv371638,362,259 - 38,378,302 (+)RGD
Celera1638,772,441 - 38,788,493 (+)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006522438   ⟹   XP_006522501
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391638,182,524 - 38,198,578 (+)NCBI
GRCm381638,362,162 - 38,378,216 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006522439   ⟹   XP_006522502
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391638,182,523 - 38,198,578 (+)NCBI
GRCm381638,362,161 - 38,378,216 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030249226   ⟹   XP_030105086
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391638,182,524 - 38,198,578 (+)NCBI
GRCm381638,362,162 - 38,378,216 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001075453   ⟸   NM_001081984
- Peptide Label: isoform 1
- UniProtKB: Q6P3F7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_071713   ⟸   NM_022318
- Peptide Label: isoform 2
- UniProtKB: Q9ES82 (UniProtKB/Swiss-Prot),   Q6P3F7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006522502   ⟸   XM_006522439
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006522501   ⟸   XM_006522438
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_030105086   ⟸   XM_030249226
- Peptide Label: isoform X3
RefSeq Acc Id: ENSMUSP00000110387   ⟸   ENSMUST00000114739
RefSeq Acc Id: ENSMUSP00000023494   ⟸   ENSMUST00000023494

Promoters
RGD ID:6827365
Promoter ID:MM_KWN:20975
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:OTTMUST00000061198,   UC007ZEU.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361638,362,016 - 38,362,516 (+)MPROMDB
RGD ID:8686186
Promoter ID:EPDNEW_M21123
Type:initiation region
Name:Popdc2_1
Description:Mus musculus popeye domain containing 2 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381638,362,215 - 38,362,275EPDNEW
RGD ID:6848669
Promoter ID:MM_TRO:3884
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain
Transcripts:MTR008393.16.854.5
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361638,376,566 - 38,377,066 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1930150 AgrOrtholog
Ensembl Genes ENSMUSG00000022803 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000023494 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000110387 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000023494 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000114739 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.120.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro cNMP-bd-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Popeye_prot UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RmlC-like_jellyroll UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:64082 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1930150 ENTREZGENE
NCBI Gene 64082 ENTREZGENE
PANTHER PTHR12101 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Popeye UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Popdc2 PhenoGen
Superfamily-SCOP SSF51206 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt POPD2_MOUSE UniProtKB/Swiss-Prot
  Q6P3F7 ENTREZGENE, UniProtKB/TrEMBL
  Q9ES82 ENTREZGENE