Gkn1 (gastrokine 1) - Rat Genome Database
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Gene: Gkn1 (gastrokine 1) Mus musculus
Analyze
Symbol: Gkn1
Name: gastrokine 1
RGD ID: 1549983
MGI Page MGI
Description: Orthologous to human GKN1 (gastrokine 1); INTERACTS WITH benzo[a]pyrene; folic acid; pirinixic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 18 kDa antrum mucosa protein; 2200002K21Rik; AMP-; AMP-18; BRIC; BRICD1; Fov; foveolin; gastrokine-1; protein CA11 homolog
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39687,322,635 - 87,327,897 (-)NCBIGRCm39mm39
GRCm39 Ensembl687,322,632 - 87,327,924 (-)Ensembl
GRCm38687,345,653 - 87,350,915 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl687,345,650 - 87,350,942 (-)EnsemblGRCm38mm10GRCm38
MGSCv37687,295,647 - 87,300,909 (-)NCBIGRCm37mm9NCBIm37
MGSCv36687,311,287 - 87,316,549 (-)NCBImm8
Celera689,284,666 - 89,289,929 (-)NCBICelera
Cytogenetic Map6D1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:16141072   PMID:16141073   PMID:17277741   PMID:18558092   PMID:21873635   PMID:25919700   PMID:27626380  


Genomics

Comparative Map Data
Gkn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39687,322,635 - 87,327,897 (-)NCBIGRCm39mm39
GRCm39 Ensembl687,322,632 - 87,327,924 (-)Ensembl
GRCm38687,345,653 - 87,350,915 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl687,345,650 - 87,350,942 (-)EnsemblGRCm38mm10GRCm38
MGSCv37687,295,647 - 87,300,909 (-)NCBIGRCm37mm9NCBIm37
MGSCv36687,311,287 - 87,316,549 (-)NCBImm8
Celera689,284,666 - 89,289,929 (-)NCBICelera
Cytogenetic Map6D1NCBI
GKN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl268,974,573 - 68,980,974 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl268,974,573 - 68,980,980 (+)EnsemblGRCh38hg38GRCh38
GRCh38268,974,636 - 68,980,976 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37269,201,768 - 69,208,108 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36269,055,209 - 69,061,616 (+)NCBINCBI36hg18NCBI36
Build 34269,113,417 - 69,119,763NCBI
Celera269,052,436 - 69,058,843 (+)NCBI
Cytogenetic Map2p13.3NCBI
HuRef268,937,927 - 68,944,334 (+)NCBIHuRef
CHM1_1269,131,023 - 69,137,429 (+)NCBICHM1_1
Gkn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24119,790,101 - 119,795,389 (-)NCBI
Rnor_6.0 Ensembl4119,143,070 - 119,148,358 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04119,143,070 - 119,148,358 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04183,711,680 - 183,717,243 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44121,496,151 - 121,501,439 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14121,740,631 - 121,745,920 (-)NCBI
Celera4108,760,377 - 108,765,665 (-)NCBICelera
Cytogenetic Map4q34NCBI
Gkn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542416,046,662 - 16,049,687 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542416,046,662 - 16,051,235 (-)NCBIChiLan1.0ChiLan1.0
LOC100993461
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A70,137,447 - 70,143,918 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A70,137,447 - 70,144,040 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A69,015,692 - 69,022,155 (+)NCBIMhudiblu_PPA_v0panPan3
GKN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1067,788,110 - 67,793,589 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11067,788,329 - 67,793,445 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Gkn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493649113,259,073 - 13,264,213 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GKN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl373,420,396 - 73,426,476 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1373,420,359 - 73,426,472 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2376,861,574 - 76,867,686 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GKN1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11438,145,076 - 38,291,187 (-)NCBI
ChlSab1.1 Ensembl1438,145,559 - 38,152,126 (-)Ensembl


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487426034Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396656149Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396656149Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396656149Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396656149Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63866962592607450Mouse
1300618Pgia19_mproteoglycan induced arthritis 19 (mouse)Not determined64531405987426034Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645314059128835032Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46935985136423692Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648720000125360000Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648720000148450000Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648726556125356785Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652161713116155267Mouse
4141028Mclr_mmethylcholanthrene lymphoma resistance (mouse)Not determined5437342788379171Mouse
15039373Adip28_madiposity 28 (mouse)65630821190308211Mouse
15039375Bw41_mbody weight QTL 41 (mouse)65630821190308211Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65844758392447710Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65854043392540433Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66005768094057799Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66348473897484905Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666713869100714031Mouse
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670425898104426034Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670425898104426034Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670425898104426034Mouse
1302020Bbaa20_mB.burgdorferi-associated arthritis 20 (mouse)Not determined67132262193464093Mouse
1300869Stheal5_msoft tissue heal 5 (mouse)Not determined671575060105575178Mouse
1300954Fcsa1_mfemoral cross-sectional area 1 (mouse)Not determined671981024105981170Mouse
1301521Pas1c_mpulmonary adenoma susceptibility 1c (mouse)Not determined671981024105981170Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673500000134700000Mouse
1301320Ots1_movarian teratoma susceptibility 1 (mouse)Not determined675447583104503555Mouse
1301571Arrd1_mage-related retinal degeneration 1 (mouse)Not determined67554435692607450Mouse
1300674Nidd3n_mnon-insulin-dependent diabetes mellitus 3 in NSY (mouse)Not determined67554435694225955Mouse
10412195Efw_mepididymal fat weight (mouse)Not determined67554435694225955Mouse
10043901Pfat5_mpredicted fat percentage 5 (mouse)Not determined675607306109607450Mouse
10412208Cypr4_mcytokine production 4 (mouse)Not determined675716503109716697Mouse
1357875Pfat2_mpredicted fat percentage 2 (mouse)Not determined676463949110464093Mouse
14697704Stsl4_mSalmonella typhimurium susceptibility locus 4 (mouse)67710000090000000Mouse
13824985Alh1_mamplitude of lateral head displacement 1 (mouse)67800000097000000Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678629504121115387Mouse
14696731Pairq1_mP. aeruginosa infection resistance QTL 1 (mouse)681500000102200000Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683713869147052561Mouse
11251720Ewc4_methanol withdrawal and consumption 4 (mouse)684122513118122513Mouse
1301687Mnic2_mmacronutrient intake (mouse)Not determined686806805113544602Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:204
Count of miRNA genes:165
Interacting mature miRNAs:183
Transcripts:ENSMUST00000032129
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_025466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC153853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008640 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK009145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK019050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK028136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY139183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY456960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC099446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC132540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC132542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000032129   ⟹   ENSMUSP00000032129
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl687,345,650 - 87,350,942 (-)Ensembl
RefSeq Acc Id: NM_025466   ⟹   NP_079742
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39687,322,635 - 87,327,897 (-)NCBI
GRCm38687,345,653 - 87,350,915 (-)ENTREZGENE
MGSCv37687,295,647 - 87,300,909 (-)RGD
Celera689,284,666 - 89,289,929 (-)RGD
cM Map6 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_079742   ⟸   NM_025466
- Peptide Label: precursor
- UniProtKB: Q9CR36 (UniProtKB/Swiss-Prot),   Q53YU8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000032129   ⟸   ENSMUST00000032129
Protein Domains
BRICHOS

Promoters
RGD ID:6890322
Promoter ID:EPDNEW_M8612
Type:multiple initiation site
Name:Gkn1_1
Description:Mus musculus gastrokine 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38687,350,911 - 87,350,971EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1913533 AgrOrtholog
Ensembl Genes ENSMUSG00000030050 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000032129 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000032129 ENTREZGENE, UniProtKB/TrEMBL
InterPro BRICHOS_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:66283 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1913533 ENTREZGENE
NCBI Gene 66283 ENTREZGENE
Pfam BRICHOS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gkn1 PhenoGen
PROSITE BRICHOS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART BRICHOS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt GKN1_MOUSE UniProtKB/Swiss-Prot
  Q53YU8 ENTREZGENE, UniProtKB/TrEMBL
  Q9CR36 ENTREZGENE
UniProt Secondary Q9CTZ5 UniProtKB/Swiss-Prot
  Q9D7K7 UniProtKB/Swiss-Prot