Capza2 (capping actin protein of muscle Z-line subunit alpha 2) - Rat Genome Database

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Gene: Capza2 (capping actin protein of muscle Z-line subunit alpha 2) Rattus norvegicus
Analyze
Symbol: Capza2
Name: capping actin protein of muscle Z-line subunit alpha 2
RGD ID: 1549770
Description: Predicted to enable actin filament binding activity. Predicted to be involved in actin cytoskeleton organization and barbed-end actin filament capping. Predicted to be located in brush border; cortical cytoskeleton; and membrane. Predicted to be part of F-actin capping protein complex. Orthologous to human CAPZA2 (capping actin protein of muscle Z-line subunit alpha 2); INTERACTS WITH 2,6-dinitrotoluene; 3H-1,2-dithiole-3-thione; 7,12-dimethyltetraphene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: capping actin protein of muscle Z-line alpha subunit 2; capping protein (actin filament) muscle Z-line, alpha 2; capZ alpha-2; F-actin-capping protein subunit alpha-2; MGC124519
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2445,978,142 - 46,014,032 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl445,977,807 - 46,013,864 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx450,970,338 - 51,006,220 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0446,891,344 - 46,927,228 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0445,307,193 - 45,343,027 (+)NCBIRnor_WKY
Rnor_6.0444,936,290 - 44,972,270 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl444,936,290 - 44,972,267 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0445,541,352 - 45,577,242 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4443,293,339 - 43,329,229 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera441,250,212 - 41,286,106 (+)NCBICelera
Cytogenetic Map4q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:18723693   PMID:19056867   PMID:19806181   PMID:20458337   PMID:22114352   PMID:23106098   PMID:23376485   PMID:23533145   PMID:24625528   PMID:29476059   PMID:30053369  


Genomics

Comparative Map Data
Capza2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2445,978,142 - 46,014,032 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl445,977,807 - 46,013,864 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx450,970,338 - 51,006,220 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0446,891,344 - 46,927,228 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0445,307,193 - 45,343,027 (+)NCBIRnor_WKY
Rnor_6.0444,936,290 - 44,972,270 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl444,936,290 - 44,972,267 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0445,541,352 - 45,577,242 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4443,293,339 - 43,329,229 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera441,250,212 - 41,286,106 (+)NCBICelera
Cytogenetic Map4q21NCBI
CAPZA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387116,862,587 - 116,922,049 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl7116,811,070 - 116,922,049 (+)EnsemblGRCh38hg38GRCh38
GRCh377116,502,641 - 116,562,103 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367116,289,799 - 116,346,549 (+)NCBINCBI36Build 36hg18NCBI36
Build 347116,096,513 - 116,153,263NCBI
Celera7111,310,094 - 111,366,812 (+)NCBICelera
Cytogenetic Map7q31.2NCBI
HuRef7110,868,260 - 110,924,832 (+)NCBIHuRef
CHM1_17116,436,160 - 116,492,983 (+)NCBICHM1_1
T2T-CHM13v2.07118,177,775 - 118,237,215 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27115,898,010 - 115,954,766 (+)NCBI
Capza2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39617,637,009 - 17,666,971 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl617,636,233 - 17,666,971 (+)EnsemblGRCm39 Ensembl
GRCm38617,637,010 - 17,666,972 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl617,636,234 - 17,666,972 (+)EnsemblGRCm38mm10GRCm38
MGSCv37617,587,098 - 17,616,534 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36617,587,098 - 17,616,534 (+)NCBIMGSCv36mm8
Celera617,711,860 - 17,741,278 (+)NCBICelera
Cytogenetic Map6A2NCBI
cM Map67.96NCBI
Capza2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543222,597,650 - 22,625,363 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543222,595,169 - 22,625,363 (+)NCBIChiLan1.0ChiLan1.0
CAPZA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.17121,553,544 - 121,584,566 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7121,551,401 - 121,584,566 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v07108,835,083 - 108,889,112 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
CAPZA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11455,763,586 - 55,824,629 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1455,763,249 - 55,824,629 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1455,158,956 - 55,219,790 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01455,804,051 - 55,865,221 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1455,803,837 - 55,867,161 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11455,833,570 - 55,894,697 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01455,521,744 - 55,582,875 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01455,892,878 - 55,954,033 (+)NCBIUU_Cfam_GSD_1.0
Capza2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511844,455,305 - 44,495,534 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365892,194,332 - 2,234,547 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CAPZA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1829,310,759 - 29,365,143 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11829,316,384 - 29,365,062 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21831,363,726 - 31,412,413 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CAPZA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12185,543,297 - 85,598,346 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2185,543,271 - 85,601,370 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604218,135,221 - 18,190,773 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Capza2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248272,477,645 - 2,529,055 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248272,476,987 - 2,529,067 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
BF407498  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2445,977,011 - 45,977,127 (+)MAPPERmRatBN7.2
Rnor_6.0444,935,160 - 44,935,275NCBIRnor6.0
Rnor_5.0445,540,222 - 45,540,337UniSTSRnor5.0
RGSC_v3.4443,292,209 - 43,292,324UniSTSRGSC3.4
Celera441,249,082 - 41,249,197UniSTS
RH 3.4 Map4282.8UniSTS
Cytogenetic Map4q21UniSTS
AA924038  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2446,013,643 - 46,013,849 (+)MAPPERmRatBN7.2
Rnor_6.0444,971,882 - 44,972,087NCBIRnor6.0
Rnor_5.0445,576,854 - 45,577,059UniSTSRnor5.0
RGSC_v3.4443,328,841 - 43,329,046UniSTSRGSC3.4
Celera441,285,718 - 41,285,923UniSTS
RH 3.4 Map4284.8UniSTS
Cytogenetic Map4q21UniSTS
ECD20142  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2445,978,180 - 45,978,414 (+)MAPPERmRatBN7.2
Rnor_6.0444,936,329 - 44,936,562NCBIRnor6.0
Rnor_5.0445,541,391 - 45,541,624UniSTSRnor5.0
RGSC_v3.4443,293,378 - 43,293,611UniSTSRGSC3.4
Celera441,250,251 - 41,250,484UniSTS
Cytogenetic Map4q21UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4521460278882945Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
2302371Stl22Serum triglyceride level QTL 225.15blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829457114705Rat
1358203Stl19Serum triglyceride level QTL 192.80.002blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829465958103Rat
631642Stl2Serum triglyceride level QTL 23.3blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521917856647776Rat
6478724Anxrr35Anxiety related response QTL 350.00449defecation behavior trait (VT:0010462)defecation measurement (CMO:0000997)41008408955084089Rat
6478766Anxrr47Anxiety related response QTL 470.09637locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)41008408955084089Rat
6478769Anxrr48Anxiety related response QTL 480.02514locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)41008408955084089Rat
8694374Bw155Body weight QTL 1553.390.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)41008408955084089Rat
9590304Scort17Serum corticosterone level QTL 174.960.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)41008408955084089Rat
8552906Pigfal3Plasma insulin-like growth factor 1 level QTL 3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)41008408955084089Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41081417091360527Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
2303585Bw86Body weight QTL 864body mass (VT:0001259)body weight (CMO:0000012)41467806559678065Rat
2313401Anxrr27Anxiety related response QTL 27aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)41793350862933508Rat
61412Pia2Pristane induced arthritis QTL 23.9joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)42133334362278020Rat
6909122Insul22Insulin level QTL 224.63blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)42690728575585128Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)42690728575585128Rat
8655906Rf60Renal function QTL 603.8blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)42949419581006281Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)432583980114627242Rat
11530004Niddm71Non-insulin dependent diabetes mellitus QTL 710.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)43258419952754138Rat
8552782Vie1Viral induced encephalitis QTL 126.4brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43443048482490359Rat
8552801Bw143Body weight QTL 1437.3body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)43443048482490359Rat
8552809Vie5Viral induced encephalitis QTL 525.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43443048482490359Rat
8655961Kidm43Kidney mass QTL 4318kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)436303261103194984Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
61475Aia2Adjuvant induced arthritis QTL 25.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)43950527573892441Rat
1331807Rf31Renal function QTL 312.988urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)43952426474726312Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)439524264116179656Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)44043338885433388Rat
8694439Bw168Body weight QTL 1689.570.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)44043341485433414Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44345797688457976Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)444463908148090542Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)444463908148090542Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)445456990146803430Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:133
Count of miRNA genes:103
Interacting mature miRNAs:109
Transcripts:ENSRNOT00000039017
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000090451   ⟹   ENSRNOP00000072041
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl445,978,190 - 46,013,646 (+)Ensembl
Rnor_6.0 Ensembl444,936,290 - 44,972,267 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000106630   ⟹   ENSRNOP00000097945
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl445,978,106 - 46,013,593 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000117690   ⟹   ENSRNOP00000086194
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl445,977,807 - 46,013,864 (+)Ensembl
RefSeq Acc Id: NM_001009180   ⟹   NP_001009180
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2445,978,142 - 46,014,032 (+)NCBI
Rnor_6.0444,936,290 - 44,972,270 (+)NCBI
Rnor_5.0445,541,352 - 45,577,242 (+)NCBI
RGSC_v3.4443,293,339 - 43,329,229 (+)RGD
Celera441,250,212 - 41,286,106 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001009180 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI01868 (Get FASTA)   NCBI Sequence Viewer  
  AAR16310 (Get FASTA)   NCBI Sequence Viewer  
  EDM15117 (Get FASTA)   NCBI Sequence Viewer  
  EDM15118 (Get FASTA)   NCBI Sequence Viewer  
  Q3T1K5 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001009180   ⟸   NM_001009180
- UniProtKB: Q3T1K5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000072041   ⟸   ENSRNOT00000090451
RefSeq Acc Id: ENSRNOP00000097945   ⟸   ENSRNOT00000106630
RefSeq Acc Id: ENSRNOP00000086194   ⟸   ENSRNOT00000117690

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3T1K5-F1-model_v2 AlphaFold Q3T1K5 1-286 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692893
Promoter ID:EPDNEW_R3417
Type:initiation region
Name:Capza2_1
Description:capping actin protein of muscle Z-line alpha subunit 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0444,936,322 - 44,936,382EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1549770 AgrOrtholog
BioCyc Gene G2FUF-45546 BioCyc
Ensembl Genes ENSRNOG00000056207 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000072041 ENTREZGENE
  ENSRNOP00000072041.2 UniProtKB/TrEMBL
  ENSRNOP00000086194.1 UniProtKB/TrEMBL
  ENSRNOP00000097945.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000090451 ENTREZGENE
  ENSRNOT00000090451.2 UniProtKB/TrEMBL
  ENSRNOT00000106630.1 UniProtKB/TrEMBL
  ENSRNOT00000117690.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1140.60 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.90.1150.210 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7938377 IMAGE-MGC_LOAD
InterPro CapZ_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CapZ_alpha/beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CapZ_alpha/beta_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CapZ_alpha_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  F-actin_cap_asu_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:493810 UniProtKB/Swiss-Prot
MGC_CLONE MGC:124519 IMAGE-MGC_LOAD
NCBI Gene 493810 ENTREZGENE
PANTHER PTHR10653 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam F-actin_cap_A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Capza2 PhenoGen
PRINTS FACTINCAPA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE F_ACTIN_CAPPING_A_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  F_ACTIN_CAPPING_A_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF90096 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6A4U7_RAT UniProtKB/TrEMBL
  A0A8I6ATN5_RAT UniProtKB/TrEMBL
  A0A8L2R4Z5_RAT UniProtKB/TrEMBL
  CAZA2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-03 Capza2  capping actin protein of muscle Z-line subunit alpha 2  Capza2  capping actin protein of muscle Z-line alpha subunit 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-02-11 Capza2  capping actin protein of muscle Z-line alpha subunit 2  Capza2  capping protein (actin filament) muscle Z-line, alpha 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-09-15 Capza2  capping protein (actin filament) muscle Z-line, alpha 2      Symbol and Name status set to provisional 70820 PROVISIONAL