Ighm<sup>em2Ang</sup> (immunoglobulin heavy constant mu; ZFN induced mutant2, Ang) - Rat Genome Database

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Gene: Ighmem2Ang (immunoglobulin heavy constant mu; ZFN induced mutant2, Ang) Rattus norvegicus
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Symbol: Ighmem2Ang
Name: immunoglobulin heavy constant mu; ZFN induced mutant2, Ang
RGD ID: 150523758
Description: Microinjection of Sprague-Dawley rat zygotes with ZFN mRNA specific for the JH locus resulted in the generation of a mutant animal with a 2465 bp DNA deletion, spanning the entire locus
ASSOCIATED WITH decreased B cell number; decreased IgA level; decreased IgE level; ASSOCIATED WITH B cell deficiency
Type: allele  of Ighm  
Previously known as: Ighm^[em2Ang]
Is Marker For: Strains:   SD-Ighmem2Ang  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Characterization of immunoglobulin heavy chain knockout rats. Ménoret S, etal., Eur J Immunol. 2010 Oct;40(10):2932-41. doi: 10.1002/eji.201040939.

Genomics


Related Rat Strains
The following Strains have been annotated to Ighmem2Ang


Expression


Sequence

Nucleotide Sequences


Additional Information