Tbc1d1<sup>Tn(sb)1Fkh</sup> (TBC1 domain family member 1; Sleeping Beauty induced mutant 1, Fkh) - Rat Genome Database

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Gene: Tbc1d1Tn(sb)1Fkh (TBC1 domain family member 1; Sleeping Beauty induced mutant 1, Fkh) Rattus norvegicus
Symbol: Tbc1d1Tn(sb)1Fkh
Name: TBC1 domain family member 1; Sleeping Beauty induced mutant 1, Fkh
RGD ID: 150521709
Description: The Sleeping Beauty transposon-mediated mutagenesis was used to knock out the rat Tbc1d1 gene in in rat spermatogonial stem cells from Sprague Dawley.
ASSOCIATED WITH abnormal carbohydrate metabolism; abnormal endocrine pancreas physiology; abnormal respiratory function
Type: allele  of Tbc1d1  
Previously known as: Tbc1d1^[Tn(sb)1Fkh]
Is Marker For: Strains:   SD-Tbc1d1Tn(sb)1Fkh  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


References - curated
# Reference Title Reference Citation
1. The Rab-GTPase activating protein, TBC1D1, is critical for maintaining normal glucose homeostasis and β-cell mass. Paglialunga S, etal., Appl Physiol Nutr Metab. 2017 Jun;42(6):647-655. doi: 10.1139/apnm-2016-0585. Epub 2017 Jan 31.
2. Ablating the protein TBC1D1 impairs contraction-induced sarcolemmal glucose transporter 4 redistribution but not insulin-mediated responses in rats. Whitfield J, etal., J Biol Chem. 2017 Oct 6;292(40):16653-16664. doi: 10.1074/jbc.M117.806786. Epub 2017 Aug 14.


Related Rat Strains
The following Strains have been annotated to Tbc1d1Tn(sb)1Fkh



Nucleotide Sequences

Additional Information