Ccdc39<sup>em1Jgn</sup> (coiled-coil domain containing 39; CRISPR/Cas9 induced mutant 1, Jgn) - Rat Genome Database

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Gene: Ccdc39em1Jgn (coiled-coil domain containing 39; CRISPR/Cas9 induced mutant 1, Jgn) Rattus norvegicus
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Symbol: Ccdc39em1Jgn
Name: coiled-coil domain containing 39; CRISPR/Cas9 induced mutant 1, Jgn
RGD ID: 150521525
Description: The CRISPR/Case9 system was desgined to create the progressive hydrocephalus (prh) mutation in Sprague Dawley rats. The homozygous rat carries chr2:g.120305679A>T change that creates a splice site (Ccdc39c.916+2T ) mutation in the rat Ccdc39 gene.
ASSOCIATED WITH abnormal cerebrospinal fluid flow; abnormal glymphatic system physiology; dilated lateral ventricle; ASSOCIATED WITH hydrocephalus; Ventriculomegaly
Type: allele  of Ccdc39  
Previously known as: Ccdc39^[em1Jgn]
Is Marker For: Strains:   SD-Ccdc39em1Jgn  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position: No map positions available.


Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Impaired neural differentiation and glymphatic CSF flow in the Ccdc39 rat model of neonatal hydrocephalus: genetic interaction with L1cam. Emmert AS, etal., Dis Model Mech. 2019 Nov 21;12(11). pii: 12/11/dmm040972. doi: 10.1242/dmm.040972.

Genomics


Related Rat Strains
The following Strains have been annotated to Ccdc39em1Jgn
SD-Ccdc39em1Jgn    


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences


Additional Information