Htr7<sup>em1Msu</sup> (5-hydroxytryptamine receptor 7; CRISPR/Cas9 induced mutant 1, Msu) - Rat Genome Database

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Gene: Htr7em1Msu (5-hydroxytryptamine receptor 7; CRISPR/Cas9 induced mutant 1, Msu) Rattus norvegicus
Symbol: Htr7em1Msu
Name: 5-hydroxytryptamine receptor 7; CRISPR/Cas9 induced mutant 1, Msu
RGD ID: 14696716
Description: CRISPR/Cas9 system was used to generate this mutant; this induced an 11 bp deletion in exon 1 and a 4 bp deletion in exon 2 of the Htr7 gene.
ASSOCIATED WITH decreased circulating alkaline phosphatase level; decreased circulating cholesterol level; decreased circulating triglyceride level
Type: allele  of Htr7  
Previously known as: Htr7^[em1Msu]
Is Marker For: Strains:   SD-Htr7em1Msu  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.

Phenotype Annotations     Click to see Annotation Detail View

References - curated
# Reference Title Reference Citation
1. Creation of the 5-hydroxytryptamine receptor 7 knockout rat as a tool for cardiovascular research. Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.
2. 5-HT does not lower blood pressure in the 5-HT7 knockout rat. Seitz BM, etal., Physiol Genomics. 2019 Jul 1;51(7):302-310. doi: 10.1152/physiolgenomics.00031.2019. Epub 2019 May 24.


Related Rat Strains
The following Strains have been annotated to Htr7em1Msu



Nucleotide Sequences

Additional Information