Edaradd<sup><i>swhKyo</i></sup> (EDAR-associated death domain;swh Kyo mutant) - Rat Genome Database

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Gene: EdaraddswhKyo (EDAR-associated death domain;swh Kyo mutant) Rattus norvegicus
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Symbol: EdaraddswhKyo
Name: EDAR-associated death domain;swh Kyo mutant
RGD ID: 14398765
Description: A spontaneous sparse-and-wavy (swh) mutation was identified in WTC-swh/Kyo rats. A missense mutation (C to T) in exon 6 of the swh/swh Edaradd gene was identified in the mutant rat.
ASSOCIATED WITH abnormal awl hair morphology; abnormal hair texture; abnormal mammary gland alveolus morphology; ASSOCIATED WITH hypohidrotic ectodermal dysplasia
Type: allele  of Edaradd  
Previously known as: Edaradd^[swhKyo]
Is Marker For: Strains:   WTC-swh/Kyo  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


References

References - curated
# Reference Title Reference Citation
1. Role of ectodysplasin signalling in middle ear and nasal pathology in rat and mouse models of hypohidrotic ectodermal dysplasia. Del-Pozo J, etal., Dis Model Mech. 2019 Apr 25;12(4). pii: 12/4/dmm037804. doi: 10.1242/dmm.037804.
2. A rat model of hypohidrotic ectodermal dysplasia carries a missense mutation in the Edaradd gene. Kuramoto T, etal., BMC Genet. 2011 Oct 21;12:91. doi: 10.1186/1471-2156-12-91.
3. Sparse and wavy hair: a new model for hypoplasia of hair follicle and mammary glands on rat chromosome 17. Kuramoto T, etal., J Hered. 2005 Jul-Aug;96(4):339-45. Epub 2005 Apr 13.

Genomics


Related Rat Strains
The following Strains have been annotated to EdaraddswhKyo
WTC-swh/Kyo    


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences


Additional Information