SLC5A1 (solute carrier family 5 member 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: SLC5A1 (solute carrier family 5 member 1) Sus scrofa
Analyze
Symbol: SLC5A1
Name: solute carrier family 5 member 1
RGD ID: 14295883
Description: ENCODES a protein that exhibits galactose:sodium symporter activity (ortholog); glucose:sodium symporter activity (ortholog); water transmembrane transporter activity (ortholog); INVOLVED IN chloride transmembrane transport (ortholog); glucose transmembrane transport (ortholog); intestinal absorption (ortholog); PARTICIPATES IN lactose degradation pathway; sodium-glucose cotransporter mediated glucose transport pathway; trehalose degradation pathway; ASSOCIATED WITH genetic disease (ortholog); Glucose-Galactose Malabsorption (ortholog); Malabsorption Syndromes (ortholog); FOUND IN apical plasma membrane (ortholog); brush border (ortholog); brush border membrane (ortholog); INTERACTS WITH bis(2-chloroethyl) sulfide; bisphenol A; choline
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: high affinity sodium-glucose cotransporter; Na(+)/glucose cotransporter 1; Na+/glucose cotransporter; SGLT1; sodium/glucose cotransporter 1; solute carrier family 5 (sodium/glucose cotransporter), member 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1448,628,224 - 48,705,841 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11448,566,400 - 48,704,145 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21452,053,314 - 52,149,508 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.21451,945,530 - 52,000,682 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:2247068   PMID:14681463   PMID:26924216  


Genomics

Comparative Map Data
SLC5A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1448,628,224 - 48,705,841 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11448,566,400 - 48,704,145 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21452,053,314 - 52,149,508 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.21451,945,530 - 52,000,682 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC5A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382232,043,261 - 32,113,029 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2232,043,261 - 32,113,029 (+)EnsemblGRCh38hg38GRCh38
GRCh372232,439,248 - 32,509,016 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362230,769,259 - 30,836,645 (+)NCBINCBI36Build 36hg18NCBI36
Build 342230,763,812 - 30,831,199NCBI
Celera2216,239,500 - 16,309,474 (+)NCBICelera
Cytogenetic Map22q12.3ENTREZGENE
HuRef2215,394,743 - 15,464,755 (+)NCBIHuRef
CHM1_12232,398,482 - 32,468,466 (+)NCBICHM1_1
T2T-CHM13v2.02232,507,411 - 32,577,165 (+)NCBIT2T-CHM13v2.0
Slc5a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39533,261,563 - 33,320,043 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl533,261,563 - 33,320,214 (+)EnsemblGRCm39 Ensembl
GRCm38533,104,219 - 33,162,699 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl533,104,219 - 33,162,870 (+)EnsemblGRCm38mm10GRCm38
MGSCv37533,446,868 - 33,505,348 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36533,421,091 - 33,479,554 (+)NCBIMGSCv36mm8
Celera530,580,692 - 30,638,639 (+)NCBICelera
Cytogenetic Map5B1NCBI
Slc5a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21477,553,990 - 77,618,589 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1477,553,843 - 77,618,547 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1481,996,099 - 82,060,059 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01483,236,643 - 83,300,604 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01479,681,950 - 79,745,920 (-)NCBIRnor_WKY
Rnor_6.01482,910,448 - 82,975,303 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1482,909,981 - 82,975,263 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01483,595,212 - 83,660,531 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41483,311,232 - 83,370,657 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11483,313,626 - 83,376,968 (-)NCBI
Celera1476,469,843 - 76,534,501 (-)NCBICelera
Cytogenetic Map14q21NCBI
Slc5a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554556,158,959 - 6,236,189 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554556,158,773 - 6,236,950 (+)NCBIChiLan1.0ChiLan1.0
SLC5A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12230,924,169 - 30,992,046 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2230,924,169 - 30,992,046 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02213,070,853 - 13,140,948 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
SLC5A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12624,884,853 - 24,956,190 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2624,884,129 - 24,958,122 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2624,753,966 - 24,825,294 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02625,271,492 - 25,342,861 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2625,271,492 - 25,344,793 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12624,970,435 - 25,041,763 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02625,233,313 - 25,304,655 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02625,294,732 - 25,366,070 (+)NCBIUU_Cfam_GSD_1.0
SLC5A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11914,924,954 - 14,999,369 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1914,928,160 - 15,002,498 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045111,104,887 - 111,182,726 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc5a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247478,452,616 - 8,540,421 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247478,368,446 - 8,542,573 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 5 1
Low 5 3 2 18 2 2 1
Below cutoff 3 3 2 5 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000010993   ⟹   ENSSSCP00000010706
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1448,628,224 - 48,705,841 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000052141   ⟹   ENSSSCP00000033188
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1448,566,343 - 48,705,841 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000062401   ⟹   ENSSSCP00000034128
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1448,629,684 - 48,702,296 (+)Ensembl
RefSeq Acc Id: NM_001164021   ⟹   NP_001157493
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11448,628,225 - 48,704,145 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021072101   ⟹   XP_020927760
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11448,566,400 - 48,704,144 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001157493 (Get FASTA)   NCBI Sequence Viewer  
  XP_020927760 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA31122 (Get FASTA)   NCBI Sequence Viewer  
  AMN88558 (Get FASTA)   NCBI Sequence Viewer  
  P26429 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_020927760   ⟸   XM_021072101
- Peptide Label: isoform X1
- UniProtKB: A0A4X1V5W6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001157493   ⟸   NM_001164021
- UniProtKB: A0A286ZRN2 (UniProtKB/TrEMBL),   A0A4X1V5B9 (UniProtKB/TrEMBL),   A0A140H1A0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000010706   ⟸   ENSSSCT00000010993
RefSeq Acc Id: ENSSSCP00000033188   ⟸   ENSSSCT00000052141
RefSeq Acc Id: ENSSSCP00000034128   ⟸   ENSSSCT00000062401


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000010036 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005040144 UniProtKB/TrEMBL
  ENSSSCG00015060457 UniProtKB/TrEMBL
  ENSSSCG00025035995 UniProtKB/TrEMBL
  ENSSSCG00030020249 UniProtKB/TrEMBL
  ENSSSCG00035020784 UniProtKB/TrEMBL
  ENSSSCG00040006018 UniProtKB/TrEMBL
  ENSSSCG00045001570 UniProtKB/TrEMBL
  ENSSSCG00050073304 UniProtKB/TrEMBL
  ENSSSCG00055010749 UniProtKB/TrEMBL
  ENSSSCG00060075649 UniProtKB/TrEMBL
  ENSSSCG00065059797 UniProtKB/TrEMBL
  ENSSSCG00070021818 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000010706 ENTREZGENE
  ENSSSCP00000010706.4 UniProtKB/TrEMBL
  ENSSSCP00000033188.2 UniProtKB/TrEMBL
  ENSSSCP00000034128 ENTREZGENE
  ENSSSCP00000034128.3 UniProtKB/TrEMBL
  ENSSSCP00005040105.1 UniProtKB/TrEMBL
  ENSSSCP00015032689.1 UniProtKB/TrEMBL
  ENSSSCP00015032848.1 UniProtKB/TrEMBL
  ENSSSCP00015032933.1 UniProtKB/TrEMBL
  ENSSSCP00025020993.1 UniProtKB/TrEMBL
  ENSSSCP00025021007.1 UniProtKB/TrEMBL
  ENSSSCP00030012544.1 UniProtKB/TrEMBL
  ENSSSCP00030012561.1 UniProtKB/TrEMBL
  ENSSSCP00030012565.1 UniProtKB/TrEMBL
  ENSSSCP00035010338.1 UniProtKB/TrEMBL
  ENSSSCP00035010345.1 UniProtKB/TrEMBL
  ENSSSCP00035010348.1 UniProtKB/TrEMBL
  ENSSSCP00035010352.1 UniProtKB/TrEMBL
  ENSSSCP00040003135.1 UniProtKB/TrEMBL
  ENSSSCP00040003139.1 UniProtKB/TrEMBL
  ENSSSCP00045001615.1 UniProtKB/TrEMBL
  ENSSSCP00045001628.1 UniProtKB/TrEMBL
  ENSSSCP00050043416.1 UniProtKB/TrEMBL
  ENSSSCP00050043426.1 UniProtKB/TrEMBL
  ENSSSCP00050043448.1 UniProtKB/TrEMBL
  ENSSSCP00050043455.1 UniProtKB/TrEMBL
  ENSSSCP00055016756.1 UniProtKB/TrEMBL
  ENSSSCP00055016846.1 UniProtKB/TrEMBL
  ENSSSCP00060045300.1 UniProtKB/TrEMBL
  ENSSSCP00060045357.1 UniProtKB/TrEMBL
  ENSSSCP00060045424.1 UniProtKB/TrEMBL
  ENSSSCP00060045453.1 UniProtKB/TrEMBL
  ENSSSCP00065035670.1 UniProtKB/TrEMBL
  ENSSSCP00065035673.1 UniProtKB/TrEMBL
  ENSSSCP00070036548.1 UniProtKB/TrEMBL
  ENSSSCP00070036560.1 UniProtKB/TrEMBL
  ENSSSCP00070036571.1 UniProtKB/TrEMBL
  ENSSSCP00070036586.1 UniProtKB/TrEMBL
  ENSSSCP00070036602.1 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000010993 ENTREZGENE
  ENSSSCT00000010993.5 UniProtKB/TrEMBL
  ENSSSCT00000052141.2 UniProtKB/TrEMBL
  ENSSSCT00000062401 ENTREZGENE
  ENSSSCT00000062401.3 UniProtKB/TrEMBL
  ENSSSCT00005064908.1 UniProtKB/TrEMBL
  ENSSSCT00015080830.1 UniProtKB/TrEMBL
  ENSSSCT00015081198.1 UniProtKB/TrEMBL
  ENSSSCT00015081392.1 UniProtKB/TrEMBL
  ENSSSCT00025049074.1 UniProtKB/TrEMBL
  ENSSSCT00025049114.1 UniProtKB/TrEMBL
  ENSSSCT00030028027.1 UniProtKB/TrEMBL
  ENSSSCT00030028063.1 UniProtKB/TrEMBL
  ENSSSCT00030028072.1 UniProtKB/TrEMBL
  ENSSSCT00035027052.1 UniProtKB/TrEMBL
  ENSSSCT00035027070.1 UniProtKB/TrEMBL
  ENSSSCT00035027078.1 UniProtKB/TrEMBL
  ENSSSCT00035027086.1 UniProtKB/TrEMBL
  ENSSSCT00040007946.1 UniProtKB/TrEMBL
  ENSSSCT00040007964.1 UniProtKB/TrEMBL
  ENSSSCT00045002529.1 UniProtKB/TrEMBL
  ENSSSCT00045002558.1 UniProtKB/TrEMBL
  ENSSSCT00050100168.1 UniProtKB/TrEMBL
  ENSSSCT00050100184.1 UniProtKB/TrEMBL
  ENSSSCT00050100210.1 UniProtKB/TrEMBL
  ENSSSCT00050100219.1 UniProtKB/TrEMBL
  ENSSSCT00055021175.1 UniProtKB/TrEMBL
  ENSSSCT00055021273.1 UniProtKB/TrEMBL
  ENSSSCT00060103623.1 UniProtKB/TrEMBL
  ENSSSCT00060103716.1 UniProtKB/TrEMBL
  ENSSSCT00060103862.1 UniProtKB/TrEMBL
  ENSSSCT00060103926.1 UniProtKB/TrEMBL
  ENSSSCT00065081899.1 UniProtKB/TrEMBL
  ENSSSCT00065081904.1 UniProtKB/TrEMBL
  ENSSSCT00070043427.1 UniProtKB/TrEMBL
  ENSSSCT00070043441.1 UniProtKB/TrEMBL
  ENSSSCT00070043453.1 UniProtKB/TrEMBL
  ENSSSCT00070043469.1 UniProtKB/TrEMBL
  ENSSSCT00070043485.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1730.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Na/Glc_symporter_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Na/solute_symporter UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Na/solute_symporter_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:397113 UniProtKB/TrEMBL
NCBI Gene SLC5A1 ENTREZGENE
Pfam SSF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE NA_SOLUT_SYMP_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NA_SOLUT_SYMP_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NA_SOLUT_SYMP_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs sss UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A140H1A0 ENTREZGENE
  A0A286ZNZ2_PIG UniProtKB/TrEMBL
  A0A286ZRN2 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1V4S5_PIG UniProtKB/TrEMBL
  A0A4X1V4U2_PIG UniProtKB/TrEMBL
  A0A4X1V5B9 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1V5W6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0PEX8_PIG UniProtKB/TrEMBL
  A0A8D0Z617_PIG UniProtKB/TrEMBL
  A0A8D1WX41_PIG UniProtKB/TrEMBL
  F1RLV1_PIG UniProtKB/TrEMBL
  P26429 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary A0A140H1A0 UniProtKB/TrEMBL
VGNC ID VGNC:93140 ENTREZGENE