POR (P450 (cytochrome) oxidoreductase) - Rat Genome Database

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Gene: POR (P450 (cytochrome) oxidoreductase) Sus scrofa
Analyze
Symbol: POR
Name: P450 (cytochrome) oxidoreductase
RGD ID: 14295521
Description: ENCODES a protein that exhibits cytochrome-b5 reductase activity, acting on NAD(P)H (ortholog); electron transfer activity (ortholog); enzyme binding (ortholog); INVOLVED IN carnitine metabolic process (ortholog); cellular response to follicle-stimulating hormone stimulus (ortholog); cellular response to gonadotropin stimulus (ortholog); PARTICIPATES IN aldosterone biosynthetic pathway; cortisol biosynthetic pathway; doxorubicin pharmacokinetics pathway; ASSOCIATED WITH amenorrhea (ortholog); Antley-Bixler syndrome (ortholog); Antley-Bixler Syndrome with Genital Anomalies and Disordered Steroidogenesis (ortholog); FOUND IN intracellular membrane-bounded organelle (ortholog); membrane (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CPR; NADPH--cytochrome P450 reductase; NADPH-cytochrome P-450 oxidoreductase; P450R
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl310,212,735 - 10,281,833 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1310,212,734 - 10,272,184 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:3098240   PMID:3099837   PMID:14681463  


Genomics

Comparative Map Data
POR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl310,212,735 - 10,281,833 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1310,212,734 - 10,272,184 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
POR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl775,899,200 - 75,986,855 (+)EnsemblGRCh38hg38GRCh38
GRCh38775,915,155 - 75,986,855 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37775,544,473 - 75,616,173 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36775,382,356 - 75,454,109 (+)NCBINCBI36hg18NCBI36
Build 34775,227,957 - 75,260,823NCBI
Celera770,412,991 - 70,484,717 (+)NCBI
Cytogenetic Map7q11.23NCBI
HuRef770,631,215 - 70,702,985 (+)NCBIHuRef
CHM1_1775,474,511 - 75,546,243 (+)NCBICHM1_1
CRA_TCAGchr7v2774,877,484 - 74,949,237 (+)NCBI
Por
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395135,698,894 - 135,764,180 (+)NCBIGRCm39mm39
GRCm39 Ensembl5135,698,887 - 135,764,180 (+)Ensembl
GRCm385135,670,040 - 135,735,326 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5135,670,033 - 135,735,326 (+)EnsemblGRCm38mm10GRCm38
MGSCv375136,165,084 - 136,211,195 (+)NCBIGRCm37mm9NCBIm37
MGSCv365135,973,841 - 136,019,952 (+)NCBImm8
Celera5132,696,393 - 132,742,504 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map575.34NCBI
Por
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21220,951,058 - 20,999,198 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1220,951,058 - 20,999,245 (-)Ensembl
Rnor_6.01223,998,411 - 24,017,063 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1223,998,411 - 24,046,814 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01225,995,663 - 26,014,366 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41222,078,629 - 22,097,301 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11222,065,892 - 22,141,603 (-)NCBI
Celera1222,713,689 - 22,732,174 (-)NCBICelera
Cytogenetic Map12q12NCBI
Por
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545614,698,589 - 14,748,520 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545614,698,589 - 14,748,520 (+)NCBIChiLan1.0ChiLan1.0
LOC100990437
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1782,364,311 - 82,437,530 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl782,364,418 - 82,437,530 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0768,035,021 - 68,105,934 (-)NCBIMhudiblu_PPA_v0panPan3
POR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.167,247,780 - 7,316,282 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl67,263,574 - 7,316,297 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha68,984,488 - 9,012,689 (+)NCBI
ROS_Cfam_1.067,068,561 - 7,137,106 (+)NCBI
UMICH_Zoey_3.167,077,907 - 7,106,119 (+)NCBI
UNSW_CanFamBas_1.067,041,376 - 7,069,585 (+)NCBI
UU_Cfam_GSD_1.067,204,608 - 7,232,825 (+)NCBI
LOC101965545
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344131,708,573 - 131,760,586 (+)NCBI
SpeTri2.0NW_0049365432,275,981 - 2,327,931 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC103246654
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12810,145,070 - 10,230,836 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2810,197,503 - 10,230,468 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660706,191,559 - 6,265,374 (-)NCBIVero_WHO_p1.0
LOC101712555
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474014,739,458 - 14,790,736 (+)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 2 2
Low 8 4 3 5 2 23 2 3 1
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001129959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021085552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021085553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021085554 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021085555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021085556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021085557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AEMK02000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK235544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK235667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK235821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK350886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK389491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK397492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK399337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK400743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GFLN01054804 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L33893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSSCT00000053539   ⟹   ENSSSCP00000036096
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl310,212,735 - 10,281,833 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000060878   ⟹   ENSSSCP00000058964
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl310,212,736 - 10,271,255 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000062325   ⟹   ENSSSCP00000047375
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl310,212,736 - 10,270,907 (-)Ensembl
RefSeq Acc Id: NM_001129959   ⟹   NP_001123431
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1310,212,736 - 10,270,858 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021085552   ⟹   XP_020941211
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1310,212,734 - 10,255,564 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021085553   ⟹   XP_020941212
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1310,212,734 - 10,270,907 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021085554   ⟹   XP_020941213
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1310,212,734 - 10,270,761 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021085555   ⟹   XP_020941214
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1310,212,734 - 10,246,633 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021085556   ⟹   XP_020941215
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1310,212,734 - 10,272,184 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021085557   ⟹   XP_020941216
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1310,212,734 - 10,259,418 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_020941215   ⟸   XM_021085556
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_020941212   ⟸   XM_021085553
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_020941213   ⟸   XM_021085554
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_020941216   ⟸   XM_021085557
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_020941211   ⟸   XM_021085552
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020941214   ⟸   XM_021085555
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: NP_001123431   ⟸   NM_001129959
- UniProtKB: P04175 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSSSCP00000058964   ⟸   ENSSSCT00000060878
RefSeq Acc Id: ENSSSCP00000047375   ⟸   ENSSSCT00000062325
RefSeq Acc Id: ENSSSCP00000036096   ⟸   ENSSSCT00000053539

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000038320 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000036096 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000047375 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000058964 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000053539 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000060878 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000062325 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 1.20.990.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.360 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.80 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro CysJ-like_FAD-binding UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FAD-bd_FR_type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Flavdoxin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Flavodoxin/NO_synth UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Flavoprot_Pyr_Nucl_cyt_Rdtase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Flavoprotein-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FNR_nucleotide-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NADPH_Cyt_P450_Rdtase_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  OxRdtase_FAD/NAD-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P450R UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Riboflavin_synthase-like_b-brl UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:100170114 UniProtKB/Swiss-Prot
NCBI Gene POR ENTREZGENE
Pfam FAD_binding_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Flavodoxin_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD_binding_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PIRSF P450R UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS FLAVODOXIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FPNCR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE FAD_FR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FLAVODOXIN_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52218 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52343 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF63380 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A286ZXA3_PIG UniProtKB/TrEMBL
  A0A287AU33_PIG UniProtKB/TrEMBL
  A0A287BS12_PIG UniProtKB/TrEMBL
  A0A480F3I9_PIG UniProtKB/TrEMBL
  A0A480ITB0_PIG UniProtKB/TrEMBL
  A0A480XE60_PIG UniProtKB/TrEMBL
  NCPR_PIG UniProtKB/Swiss-Prot, ENTREZGENE