ENO4 (enolase 4) - Rat Genome Database

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Gene: ENO4 (enolase 4) Sus scrofa
Analyze
Symbol: ENO4
Name: enolase 4
RGD ID: 14295317
Description: ENCODES a protein that exhibits lyase activity (inferred); magnesium ion binding (inferred); phosphopyruvate hydratase activity (inferred); INVOLVED IN cilium organization (ortholog); flagellated sperm motility (ortholog); glycolytic process (ortholog); ASSOCIATED WITH genetic disease (ortholog); male infertility (ortholog); FOUND IN sperm principal piece (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: enolase family member 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14127,036,991 - 127,066,048 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114127,032,217 - 127,063,660 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214138,346,087 - 138,372,823 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
ENO4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14127,036,991 - 127,066,048 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114127,032,217 - 127,063,660 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214138,346,087 - 138,372,823 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ENO4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810116,849,499 - 116,912,375 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10116,849,499 - 116,911,788 (+)EnsemblGRCh38hg38GRCh38
GRCh3710118,609,010 - 118,642,112 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610118,598,662 - 118,632,102 (+)NCBINCBI36Build 36hg18NCBI36
Celera10112,338,464 - 112,371,477 (+)NCBICelera
Cytogenetic Map10q25.3NCBI
HuRef10112,237,174 - 112,270,284 (+)NCBIHuRef
CHM1_110118,892,138 - 118,925,231 (+)NCBICHM1_1
T2T-CHM13v2.010117,743,799 - 117,806,708 (+)NCBIT2T-CHM13v2.0
Eno4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391958,922,490 - 58,959,853 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1958,931,857 - 58,959,853 (+)EnsemblGRCm39 Ensembl
GRCm381958,934,058 - 58,971,421 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1958,943,425 - 58,971,421 (+)EnsemblGRCm38mm10GRCm38
MGSCv371959,017,915 - 59,045,911 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361958,996,676 - 59,024,664 (+)NCBIMGSCv36mm8
Celera1961,140,864 - 61,167,609 (+)NCBICelera
Cytogenetic Map19D2NCBI
cM Map1954.55NCBI
Eno4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81268,073,318 - 268,113,494 (+)NCBIGRCr8
mRatBN7.21258,096,406 - 258,119,811 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1258,096,432 - 258,128,984 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1266,303,205 - 266,326,608 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01273,009,212 - 273,032,615 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01265,651,004 - 265,674,419 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01280,097,061 - 280,129,750 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1280,103,695 - 280,127,073 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01287,466,573 - 287,492,842 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41265,466,484 - 265,489,862 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11265,677,560 - 265,700,473 (+)NCBI
Celera1253,754,579 - 253,777,963 (+)NCBICelera
Cytogenetic Map1q55NCBI
Eno4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543121,625,808 - 21,650,282 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543121,625,808 - 21,650,282 (+)NCBIChiLan1.0ChiLan1.0
ENO4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28128,719,042 - 128,754,918 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110128,724,381 - 128,759,764 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010113,435,222 - 113,466,275 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110116,861,381 - 116,893,792 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10116,861,395 - 116,922,607 (+)Ensemblpanpan1.1panPan2
ENO4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12827,392,650 - 27,418,725 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2827,392,741 - 27,418,711 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2827,542,627 - 27,568,674 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02827,929,019 - 27,955,083 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2827,929,053 - 27,955,074 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12827,483,678 - 27,509,755 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02827,503,755 - 27,529,804 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02827,691,764 - 27,717,825 (+)NCBIUU_Cfam_GSD_1.0
Eno4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721318,777,898 - 18,800,978 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364866,760,400 - 6,783,066 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364866,760,400 - 6,785,098 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ENO4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19109,658,378 - 109,695,425 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9109,660,889 - 109,692,999 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604870,915,781 - 70,948,872 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eno4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473729,655,579 - 29,758,186 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473729,655,799 - 29,758,109 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ENO4
1075 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system endocrine system hemolymphoid system nervous system renal system reproductive system respiratory system
High
Medium
Low 3 23 2 2
Below cutoff 3 2 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000011664   ⟹   ENSSSCP00000011362
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl14127,037,001 - 127,063,661 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000022490   ⟹   ENSSSCP00000025529
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl14127,036,991 - 127,066,048 (+)Ensembl
RefSeq Acc Id: XM_003483559   ⟹   XP_003483607
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.114127,032,217 - 127,063,660 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005671483   ⟹   XP_005671540
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.114127,037,033 - 127,063,660 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005671484   ⟹   XP_005671541
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.114127,032,217 - 127,063,660 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013983788   ⟹   XP_013839242
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.114127,032,217 - 127,063,660 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021073403   ⟹   XP_020929062
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.114127,032,228 - 127,063,660 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021073404   ⟹   XP_020929063
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.114127,032,217 - 127,063,660 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_003483607   ⟸   XM_003483559
- Peptide Label: isoform X1
- UniProtKB: A0A4X1SZI5 (UniProtKB/TrEMBL),   F1S4S3 (UniProtKB/TrEMBL),   A0A8D0X5R2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005671541   ⟸   XM_005671484
- Peptide Label: isoform X6
- UniProtKB: A0A8D0X5R2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020929063   ⟸   XM_021073404
- Peptide Label: isoform X3
- UniProtKB: A0A4X1SXS2 (UniProtKB/TrEMBL),   I3LN57 (UniProtKB/TrEMBL),   A0A8D0NFJ6 (UniProtKB/TrEMBL),   A0A8D0X2G6 (UniProtKB/TrEMBL),   A0A8D1GGF6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013839242   ⟸   XM_013983788
- Peptide Label: isoform X5
- UniProtKB: A0A481BB88 (UniProtKB/TrEMBL),   A0A8D0NFJ6 (UniProtKB/TrEMBL),   A0A8D0X2G6 (UniProtKB/TrEMBL),   A0A8D1GGF6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020929062   ⟸   XM_021073403
- Peptide Label: isoform X2
- UniProtKB: A0A8D0X5R2 (UniProtKB/TrEMBL),   A0A8D1EXB5 (UniProtKB/TrEMBL),   A0A8D1UFK7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005671540   ⟸   XM_005671483
- Peptide Label: isoform X4
- UniProtKB: A0A4X1SXR4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000011362   ⟸   ENSSSCT00000011664
RefSeq Acc Id: ENSSSCP00000025529   ⟸   ENSSSCT00000022490
Protein Domains
Enolase C-terminal TIM barrel   Enolase N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000010664 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015034313 UniProtKB/TrEMBL
  ENSSSCG00025058877 UniProtKB/TrEMBL
  ENSSSCG00030046538 UniProtKB/TrEMBL
  ENSSSCG00035016509 UniProtKB/TrEMBL
  ENSSSCG00040048707 UniProtKB/TrEMBL
  ENSSSCG00045002927 UniProtKB/TrEMBL
  ENSSSCG00055020178 UniProtKB/TrEMBL
  ENSSSCG00060001563 UniProtKB/TrEMBL
  ENSSSCG00065059942 UniProtKB/TrEMBL
  ENSSSCG00070005112 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000011664 ENTREZGENE
  ENSSSCT00000011664.5 UniProtKB/TrEMBL
  ENSSSCT00000022490 ENTREZGENE
  ENSSSCT00000022490.3 UniProtKB/TrEMBL
  ENSSSCT00015045684.1 UniProtKB/TrEMBL
  ENSSSCT00025080610.1 UniProtKB/TrEMBL
  ENSSSCT00025080922.1 UniProtKB/TrEMBL
  ENSSSCT00030064912.1 UniProtKB/TrEMBL
  ENSSSCT00030064943.1 UniProtKB/TrEMBL
  ENSSSCT00035021105.1 UniProtKB/TrEMBL
  ENSSSCT00035021108.1 UniProtKB/TrEMBL
  ENSSSCT00040065638.1 UniProtKB/TrEMBL
  ENSSSCT00045004686.1 UniProtKB/TrEMBL
  ENSSSCT00045004697.1 UniProtKB/TrEMBL
  ENSSSCT00055039563.1 UniProtKB/TrEMBL
  ENSSSCT00055039665.1 UniProtKB/TrEMBL
  ENSSSCT00060001908.1 UniProtKB/TrEMBL
  ENSSSCT00065082093.1 UniProtKB/TrEMBL
  ENSSSCT00065082100.1 UniProtKB/TrEMBL
  ENSSSCT00070009715.1 UniProtKB/TrEMBL
  ENSSSCT00070009727.1 UniProtKB/TrEMBL
  ENSSSCT00070009744.1 UniProtKB/TrEMBL
  ENSSSCT00070009757.1 UniProtKB/TrEMBL
Gene3D-CATH 3.20.20.120 UniProtKB/TrEMBL
  3.30.390.10 UniProtKB/TrEMBL
InterPro DD_ENO4 UniProtKB/TrEMBL
  Enolase UniProtKB/TrEMBL
  Enolase-like_C_sf UniProtKB/TrEMBL
  Enolase-like_N UniProtKB/TrEMBL
  Enolase_C UniProtKB/TrEMBL
  Enolase_N UniProtKB/TrEMBL
KEGG Report ssc:100158218 UniProtKB/TrEMBL
NCBI Gene ENO4 ENTREZGENE
PANTHER ENOLASE 4 UniProtKB/TrEMBL
  PTHR11902 UniProtKB/TrEMBL
Pfam Enolase_C UniProtKB/TrEMBL
SMART Enolase_C UniProtKB/TrEMBL
  Enolase_N UniProtKB/TrEMBL
Superfamily-SCOP SSF51604 UniProtKB/TrEMBL
  SSF54826 UniProtKB/TrEMBL
UniProt A0A481BB88 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1SXP0_PIG UniProtKB/TrEMBL
  A0A4X1SXR4 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1SXS2 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1SZI5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0NFJ6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0X2G6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0X5R2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1EXB5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1GGF6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1UFK7 ENTREZGENE, UniProtKB/TrEMBL
  F1S4S3 ENTREZGENE, UniProtKB/TrEMBL
  I3LN57 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:87704 ENTREZGENE