ASB10 (ankyrin repeat and SOCS box containing 10) - Rat Genome Database

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Gene: ASB10 (ankyrin repeat and SOCS box containing 10) Sus scrofa
Analyze
Symbol: ASB10
Name: ankyrin repeat and SOCS box containing 10
RGD ID: 14293410
Description: INVOLVED IN intracellular signal transduction (inferred); protein ubiquitination (inferred); regulation of barbed-end actin filament capping (inferred); ASSOCIATED WITH genetic disease (ortholog); Glaucoma 1, Open Angle, F (ortholog); lethal congenital glycogen storage disease of heart (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ankyrin repeat and SOCS box protein 10
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl186,039,507 - 6,049,861 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1186,039,253 - 6,050,335 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2186,403,355 - 6,414,192 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
ASB10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl186,039,507 - 6,049,861 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1186,039,253 - 6,050,335 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2186,403,355 - 6,414,192 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ASB10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387151,175,698 - 151,187,792 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7151,175,698 - 151,187,832 (-)EnsemblGRCh38hg38GRCh38
GRCh377150,872,785 - 150,884,879 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367150,503,718 - 150,515,411 (-)NCBINCBI36Build 36hg18NCBI36
Build 347150,310,432 - 150,322,126NCBI
Celera7145,430,126 - 145,442,260 (-)NCBICelera
Cytogenetic Map7q36.1NCBI
HuRef7144,683,659 - 144,695,741 (-)NCBIHuRef
CHM1_17150,881,185 - 150,893,318 (-)NCBICHM1_1
T2T-CHM13v2.07152,348,791 - 152,360,884 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27150,202,306 - 150,214,439 (-)NCBI
Asb10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39524,737,695 - 24,745,976 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl524,737,695 - 24,745,976 (-)EnsemblGRCm39 Ensembl
GRCm38524,532,697 - 24,540,978 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl524,532,697 - 24,540,978 (-)EnsemblGRCm38mm10GRCm38
MGSCv37524,038,515 - 24,046,266 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36524,042,762 - 24,050,513 (-)NCBIMGSCv36mm8
Celera521,482,815 - 21,490,533 (-)NCBICelera
Cytogenetic Map5A3NCBI
cM Map511.93NCBI
Asb10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8411,522,531 - 11,531,946 (+)NCBIGRCr8
mRatBN7.2410,630,318 - 10,644,270 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl410,630,448 - 10,639,060 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx415,777,065 - 15,785,594 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0411,597,256 - 11,605,785 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.049,949,036 - 9,957,565 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.047,158,293 - 7,167,505 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl47,158,448 - 7,167,509 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.047,170,905 - 7,180,029 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.446,010,913 - 6,019,444 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera46,246,912 - 6,255,443 (+)NCBICelera
Cytogenetic Map4q11NCBI
Asb10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554915,597,485 - 5,609,086 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554915,597,623 - 5,609,086 (-)NCBIChiLan1.0ChiLan1.0
ASB10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26187,597,655 - 187,609,829 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1739,607,921 - 39,620,095 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07142,762,583 - 142,774,796 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17154,914,516 - 154,926,719 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7154,914,930 - 154,926,719 (-)Ensemblpanpan1.1panPan2
ASB10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11615,220,042 - 15,230,702 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1615,220,507 - 15,230,134 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1615,828,053 - 15,839,835 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01616,942,250 - 16,954,034 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1616,942,716 - 16,952,054 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11615,314,422 - 15,326,202 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01615,896,020 - 15,906,663 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01615,946,697 - 15,958,460 (-)NCBIUU_Cfam_GSD_1.0
Asb10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244051186,304,226 - 6,314,358 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365276,589,021 - 6,598,591 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365276,589,105 - 6,598,591 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ASB10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121119,360,034 - 119,372,779 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21119,360,450 - 119,371,197 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607215,330,670 - 15,342,699 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Asb10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248005,450,660 - 5,459,524 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248005,450,695 - 5,459,221 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ASB10
433 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system hemolymphoid system musculoskeletal system renal system
High
Medium 2
Low 1 2
Below cutoff 1 2 1

Sequence


RefSeq Acc Id: ENSSSCT00000025747   ⟹   ENSSSCP00000019604
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl186,039,507 - 6,049,861 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000049465   ⟹   ENSSSCP00000054310
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl186,039,507 - 6,049,858 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000053361   ⟹   ENSSSCP00000047676
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl186,039,498 - 6,049,858 (+)Ensembl
RefSeq Acc Id: XM_005657692   ⟹   XP_005657749
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1186,039,972 - 6,050,335 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013990752   ⟹   XP_013846206
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1186,039,450 - 6,050,335 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021078792   ⟹   XP_020934451
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1186,039,983 - 6,050,335 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002340291
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1186,039,428 - 6,050,335 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002340292
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1186,039,419 - 6,050,335 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002340293
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1186,039,411 - 6,050,335 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002340294
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1186,039,253 - 6,050,335 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002340295
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1186,048,127 - 6,050,335 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002340296
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1186,044,933 - 6,050,335 (+)NCBI
Sequence:
RefSeq Acc Id: XP_013846206   ⟸   XM_013990752
- Peptide Label: isoform X2
- UniProtKB: A0A4X1UL48 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005657749   ⟸   XM_005657692
- Peptide Label: isoform X3
- UniProtKB: I3L6F3 (UniProtKB/TrEMBL),   A0A8D1QTQ0 (UniProtKB/TrEMBL),   A0A8D0MVB4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020934451   ⟸   XM_021078792
- Peptide Label: isoform X1
- UniProtKB: A0A8D0MVB4 (UniProtKB/TrEMBL),   A0A8D1H6B6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000054310   ⟸   ENSSSCT00000049465
RefSeq Acc Id: ENSSSCP00000019604   ⟸   ENSSSCT00000025747
RefSeq Acc Id: ENSSSCP00000047676   ⟸   ENSSSCT00000053361
Protein Domains
SOCS box


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000029241 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015016084 UniProtKB/TrEMBL
  ENSSSCG00030008353 UniProtKB/TrEMBL
  ENSSSCG00035028042 UniProtKB/TrEMBL
  ENSSSCG00040075899 UniProtKB/TrEMBL
  ENSSSCG00045011032 UniProtKB/TrEMBL
  ENSSSCG00050039372 UniProtKB/TrEMBL
  ENSSSCG00055015535 UniProtKB/TrEMBL
  ENSSSCG00060055433 UniProtKB/TrEMBL
  ENSSSCG00065028528 UniProtKB/TrEMBL
  ENSSSCG00070018676 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000025747 ENTREZGENE
  ENSSSCT00000025747.4 UniProtKB/TrEMBL
  ENSSSCT00000049465.2 UniProtKB/TrEMBL
  ENSSSCT00015021377.1 UniProtKB/TrEMBL
  ENSSSCT00030011389.1 UniProtKB/TrEMBL
  ENSSSCT00035037113.1 UniProtKB/TrEMBL
  ENSSSCT00040105516.1 UniProtKB/TrEMBL
  ENSSSCT00045018766.1 UniProtKB/TrEMBL
  ENSSSCT00050053108.1 UniProtKB/TrEMBL
  ENSSSCT00055030629.1 UniProtKB/TrEMBL
  ENSSSCT00060075505.1 UniProtKB/TrEMBL
  ENSSSCT00065038477.1 UniProtKB/TrEMBL
  ENSSSCT00070036826.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  SOCS_box UniProtKB/TrEMBL
  SOCS_box-like_dom_sf UniProtKB/TrEMBL
KEGG Report ssc:100626709 UniProtKB/TrEMBL
NCBI Gene ASB10 ENTREZGENE
PANTHER ANKYRIN DOMAIN-CONTAINING UniProtKB/TrEMBL
  ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED UniProtKB/TrEMBL
  MYOTROPHIN UniProtKB/TrEMBL
  MYOTROPHIN-RELATED UniProtKB/TrEMBL
  SOCS BOX DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam Ank UniProtKB/TrEMBL
  Ank_2 UniProtKB/TrEMBL
  SOCS_box UniProtKB/TrEMBL
PRINTS ANKYRIN UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
  SOCS UniProtKB/TrEMBL
SMART ANK UniProtKB/TrEMBL
  SOCS_box UniProtKB/TrEMBL
Superfamily-SCOP SSF158235 UniProtKB/TrEMBL
  SSF48403 UniProtKB/TrEMBL
UniProt A0A287BCQ7_PIG UniProtKB/TrEMBL
  A0A4X1UL48 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0MVB4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1H6B6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1QTQ0 ENTREZGENE, UniProtKB/TrEMBL
  I3L6F3 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:97889 ENTREZGENE