MARVELD3 (MARVEL domain containing 3) - Rat Genome Database

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Gene: MARVELD3 (MARVEL domain containing 3) Sus scrofa
Analyze
Symbol: MARVELD3
Name: MARVEL domain containing 3
RGD ID: 14291166
Description: ENCODES a protein that exhibits mitogen-activated protein kinase kinase kinase binding (inferred); INVOLVED IN cell-cell junction organization (ortholog); negative regulation of epithelial cell migration (ortholog); negative regulation of epithelial cell proliferation (ortholog); ASSOCIATED WITH autosomal dominant dyskeratosis congenita 6 (ortholog); genetic disease (ortholog); FOUND IN bicellular tight junction (inferred); cytoplasmic vesicle (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: MARVEL domain-containing protein 3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl614,616,481 - 14,625,983 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1614,616,508 - 14,630,798 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2614,109,585 - 14,123,646 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17407547   PMID:22301074  


Genomics

Comparative Map Data
MARVELD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl614,616,481 - 14,625,983 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1614,616,508 - 14,630,798 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2614,109,585 - 14,123,646 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MARVELD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381671,626,184 - 71,641,965 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1671,626,161 - 71,642,114 (+)EnsemblGRCh38hg38GRCh38
GRCh371671,660,087 - 71,675,868 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361670,217,571 - 70,233,369 (+)NCBINCBI36Build 36hg18NCBI36
Build 341670,217,589 - 70,226,732NCBI
Celera1655,976,129 - 55,991,929 (+)NCBICelera
Cytogenetic Map16q22.2NCBI
HuRef1657,428,132 - 57,443,707 (+)NCBIHuRef
CHM1_11673,072,839 - 73,088,630 (+)NCBICHM1_1
T2T-CHM13v2.01677,443,349 - 77,459,129 (+)NCBIT2T-CHM13v2.0
Marveld3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398110,674,541 - 110,688,837 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8110,674,546 - 110,688,835 (-)EnsemblGRCm39 Ensembl
GRCm388109,947,909 - 109,962,205 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8109,947,914 - 109,962,203 (-)EnsemblGRCm38mm10GRCm38
MGSCv378112,471,809 - 112,486,105 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368112,837,043 - 112,851,301 (-)NCBIMGSCv36mm8
Celera8114,169,861 - 114,184,142 (-)NCBICelera
Cytogenetic Map8D3NCBI
cM Map857.38NCBI
Marveld3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81954,818,180 - 54,832,871 (-)NCBIGRCr8
mRatBN7.21937,908,727 - 37,923,420 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1937,905,638 - 37,923,420 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1944,721,040 - 44,735,720 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01945,374,382 - 45,389,062 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01947,683,994 - 47,698,676 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01941,710,076 - 41,724,923 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1941,710,102 - 41,724,923 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01952,533,493 - 52,548,323 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41939,815,223 - 39,829,914 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1937,312,319 - 37,327,013 (-)NCBICelera
Cytogenetic Map19q12NCBI
MARVELD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21882,517,624 - 82,533,582 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11688,448,452 - 88,464,397 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01653,369,080 - 53,385,031 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11671,463,722 - 71,477,951 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1671,463,824 - 71,477,631 (+)Ensemblpanpan1.1panPan2
MARVELD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1577,412,353 - 77,421,032 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl577,412,101 - 77,425,578 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha577,373,388 - 77,388,132 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0577,850,906 - 77,865,672 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1577,670,919 - 77,685,750 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0577,494,107 - 77,508,903 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0577,993,065 - 78,007,828 (+)NCBIUU_Cfam_GSD_1.0
Marveld3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934937,432,404 - 37,450,390 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647522,146,100 - 22,156,702 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647522,141,276 - 22,156,649 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MARVELD3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1554,748,029 - 54,765,007 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl554,748,061 - 54,765,252 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604717,551,303 - 17,567,015 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Marveld3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474613,898,857 - 13,914,032 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MARVELD3
459 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system nervous system renal system reproductive system respiratory system
High
Medium 1 1
Low 7 3 1 3 1 3 1
Below cutoff 2 2 2 11

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000003029   ⟹   ENSSSCP00000002950
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl614,616,481 - 14,630,794 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000003030   ⟹   ENSSSCP00000002951
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl614,616,482 - 14,625,983 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000073797   ⟹   ENSSSCP00000067118
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl614,616,481 - 14,619,533 (+)Ensembl
RefSeq Acc Id: NM_001243841   ⟹   NP_001230770
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1614,616,508 - 14,630,798 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001243842   ⟹   NP_001230771
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1614,616,508 - 14,625,985 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001230770   ⟸   NM_001243841
- Peptide Label: isoform 1
- UniProtKB: A0A8D1YJQ9 (UniProtKB/TrEMBL),   A0A4X1SMG1 (UniProtKB/TrEMBL),   A0A8D1EV24 (UniProtKB/TrEMBL),   A0A8D1LI64 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001230771   ⟸   NM_001243842
- Peptide Label: isoform 2
- UniProtKB: A0A8D1LIC4 (UniProtKB/TrEMBL),   A0A4X1SM37 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000067118   ⟸   ENSSSCT00000073797
RefSeq Acc Id: ENSSSCP00000002950   ⟸   ENSSSCT00000003029
RefSeq Acc Id: ENSSSCP00000002951   ⟸   ENSSSCT00000003030
Protein Domains
MARVEL


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000002734 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005024421 UniProtKB/TrEMBL
  ENSSSCG00015077319 UniProtKB/TrEMBL
  ENSSSCG00025069138 UniProtKB/TrEMBL
  ENSSSCG00030070749 UniProtKB/TrEMBL
  ENSSSCG00035069851 UniProtKB/TrEMBL
  ENSSSCG00040048468 UniProtKB/TrEMBL
  ENSSSCG00045024241 UniProtKB/TrEMBL
  ENSSSCG00050015341 UniProtKB/TrEMBL
  ENSSSCG00055019557 UniProtKB/TrEMBL
  ENSSSCG00060041943 UniProtKB/TrEMBL
  ENSSSCG00065036201 UniProtKB/TrEMBL
  ENSSSCG00070002333 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000003030 ENTREZGENE
  ENSSSCT00000003030.4 UniProtKB/TrEMBL
  ENSSSCT00000073797.1 UniProtKB/TrEMBL
  ENSSSCT00005038777.1 UniProtKB/TrEMBL
  ENSSSCT00005038841.1 UniProtKB/TrEMBL
  ENSSSCT00005038849.1 UniProtKB/TrEMBL
  ENSSSCT00015104445.1 UniProtKB/TrEMBL
  ENSSSCT00015104472.1 UniProtKB/TrEMBL
  ENSSSCT00015104541.1 UniProtKB/TrEMBL
  ENSSSCT00025095014.1 UniProtKB/TrEMBL
  ENSSSCT00025095098.1 UniProtKB/TrEMBL
  ENSSSCT00025095144.1 UniProtKB/TrEMBL
  ENSSSCT00030098960.1 UniProtKB/TrEMBL
  ENSSSCT00030098989.1 UniProtKB/TrEMBL
  ENSSSCT00030099001.1 UniProtKB/TrEMBL
  ENSSSCT00035094378.1 UniProtKB/TrEMBL
  ENSSSCT00035094390.1 UniProtKB/TrEMBL
  ENSSSCT00035094397.1 UniProtKB/TrEMBL
  ENSSSCT00040065337.1 UniProtKB/TrEMBL
  ENSSSCT00040065434.1 UniProtKB/TrEMBL
  ENSSSCT00040065479.1 UniProtKB/TrEMBL
  ENSSSCT00045041391.1 UniProtKB/TrEMBL
  ENSSSCT00045041438.1 UniProtKB/TrEMBL
  ENSSSCT00050020800.1 UniProtKB/TrEMBL
  ENSSSCT00050020812.1 UniProtKB/TrEMBL
  ENSSSCT00055038286.1 UniProtKB/TrEMBL
  ENSSSCT00055038327.1 UniProtKB/TrEMBL
  ENSSSCT00055038416.1 UniProtKB/TrEMBL
  ENSSSCT00060056885.1 UniProtKB/TrEMBL
  ENSSSCT00060056892.1 UniProtKB/TrEMBL
  ENSSSCT00065049347.1 UniProtKB/TrEMBL
  ENSSSCT00065049353.1 UniProtKB/TrEMBL
  ENSSSCT00065049358.1 UniProtKB/TrEMBL
  ENSSSCT00070004347.1 UniProtKB/TrEMBL
  ENSSSCT00070004351.1 UniProtKB/TrEMBL
InterPro Marvel UniProtKB/TrEMBL
KEGG Report ssc:100511453 UniProtKB/TrEMBL
NCBI Gene MARVELD3 ENTREZGENE
PANTHER GEO08273P1-RELATED UniProtKB/TrEMBL
  GEO08273P1-RELATED UniProtKB/TrEMBL
  MARVEL DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN UniProtKB/TrEMBL
PROSITE MARVEL UniProtKB/TrEMBL
UniProt A0A4X1SM37 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1SMG1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0Q4S4_PIG UniProtKB/TrEMBL
  A0A8D0Q4X5_PIG UniProtKB/TrEMBL
  A0A8D0Y662_PIG UniProtKB/TrEMBL
  A0A8D1EV24 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1I834_PIG UniProtKB/TrEMBL
  A0A8D1LI64 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1LIC4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1RBP3_PIG UniProtKB/TrEMBL
  A0A8D1VH66_PIG UniProtKB/TrEMBL
  A0A8D1VHI1_PIG UniProtKB/TrEMBL
  A0A8D1YJA1_PIG UniProtKB/TrEMBL
  A0A8D1YJQ9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1YKB3_PIG UniProtKB/TrEMBL
  F1S3D3_PIG UniProtKB/TrEMBL
UniProt Secondary A0A5G2QYV2 UniProtKB/TrEMBL
  A0A8D1IAD1 UniProtKB/TrEMBL
VGNC ID VGNC:90030 ENTREZGENE