FZR1 (fizzy and cell division cycle 20 related 1) - Rat Genome Database

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Gene: FZR1 (fizzy and cell division cycle 20 related 1) Sus scrofa
Analyze
Symbol: FZR1
Name: fizzy and cell division cycle 20 related 1
RGD ID: 14289700
Description: ENCODES a protein that exhibits anaphase-promoting complex binding (inferred); ubiquitin-protein transferase activator activity (inferred); INVOLVED IN anaphase-promoting complex-dependent catabolic process; negative regulation of meiotic cell cycle process involved in oocyte maturation; lens fiber cell differentiation (ortholog); ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); Polyploidy (ortholog); FOUND IN anaphase-promoting complex (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CDH1; fizzy-related protein FZR; fizzy-related protein homolog; fizzy/cell division cycle 20 related 1; FYR; FZR
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl275,118,832 - 75,146,837 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1275,122,599 - 75,164,134 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2275,783,163 - 75,789,212 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:14681463   PMID:18753608  


Genomics

Comparative Map Data
FZR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl275,118,832 - 75,146,837 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1275,122,599 - 75,164,134 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2275,783,163 - 75,789,212 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FZR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl193,506,311 - 3,538,334 (+)EnsemblGRCh38hg38GRCh38
GRCh38193,506,263 - 3,538,334 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37193,506,309 - 3,538,332 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36193,473,954 - 3,489,325 (+)NCBINCBI36hg18NCBI36
Build 34193,473,953 - 3,489,325NCBI
Celera193,443,104 - 3,473,565 (+)NCBI
Cytogenetic Map19p13.3NCBI
HuRef193,272,276 - 3,302,307 (+)NCBIHuRef
CHM1_1193,505,941 - 3,536,425 (+)NCBICHM1_1
Fzr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391081,202,713 - 81,214,204 (-)NCBIGRCm39mm39
GRCm39 Ensembl1081,202,056 - 81,214,350 (-)Ensembl
GRCm381081,366,879 - 81,378,370 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1081,366,222 - 81,378,516 (-)EnsemblGRCm38mm10GRCm38
MGSCv371080,829,624 - 80,841,115 (-)NCBIGRCm37mm9NCBIm37
MGSCv361080,770,008 - 80,781,499 (-)NCBImm8
Celera1082,387,912 - 82,399,403 (-)NCBICelera
Cytogenetic Map10C1NCBI
Fzr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.278,332,029 - 8,343,953 (+)NCBI
Rnor_6.0 Ensembl711,201,690 - 11,213,613 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0711,201,690 - 11,213,614 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0711,368,581 - 11,380,505 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.479,816,491 - 9,829,006 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.179,816,497 - 9,829,003 (+)NCBI
Celera76,521,094 - 6,533,016 (+)NCBICelera
Cytogenetic Map7q11NCBI
Fzr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554955,481,916 - 5,505,521 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554955,481,914 - 5,503,690 (+)NCBIChiLan1.0ChiLan1.0
FZR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1193,483,601 - 3,512,798 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl193,500,117 - 3,510,867 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0192,533,172 - 2,564,301 (+)NCBIMhudiblu_PPA_v0panPan3
FZR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12055,866,893 - 55,877,077 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2055,869,693 - 55,876,936 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2055,591,521 - 55,613,508 (-)NCBI
ROS_Cfam_1.02056,526,317 - 56,548,298 (-)NCBI
UMICH_Zoey_3.12055,581,995 - 55,603,964 (-)NCBI
UNSW_CanFamBas_1.02056,065,400 - 56,087,328 (-)NCBI
UU_Cfam_GSD_1.02056,264,144 - 56,286,128 (-)NCBI
Fzr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118215,827,214 - 215,833,762 (-)NCBI
SpeTri2.0NW_0049365882,000,872 - 2,007,569 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FZR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.163,272,247 - 3,300,370 (+)NCBI
ChlSab1.1 Ensembl63,288,407 - 3,298,464 (+)Ensembl
Vero_WHO_p1.0NW_0236660815,191,962 - 5,219,993 (-)NCBI
Fzr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248286,236,861 - 6,254,763 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 11
Low 10 4 3 4 2 12 2 3 3
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001012296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021081963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021081964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021081965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021081969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021081978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB192874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AEMK02000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF348673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK233094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK392452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP163094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX919710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU915719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FP016022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GFLN01116756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSSCT00000014727   ⟹   ENSSSCP00000014329
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl275,124,060 - 75,146,800 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000014728   ⟹   ENSSSCP00000014330
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl275,118,832 - 75,146,835 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000042562   ⟹   ENSSSCP00000050998
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl275,118,832 - 75,146,835 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000066430   ⟹   ENSSSCP00000038011
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl275,124,060 - 75,146,837 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000079343   ⟹   ENSSSCP00000067293
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl275,118,832 - 75,146,835 (-)Ensembl
RefSeq Acc Id: NM_001012296   ⟹   NP_001012296
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1275,125,486 - 75,131,657 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021081963   ⟹   XP_020937622
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1275,122,599 - 75,146,858 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021081964   ⟹   XP_020937623
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1275,122,599 - 75,146,855 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021081965   ⟹   XP_020937624
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1275,122,599 - 75,164,134 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021081969   ⟹   XP_020937628
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1275,122,599 - 75,146,895 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021081978   ⟹   XP_020937637
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1275,122,599 - 75,146,855 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_020937624   ⟸   XM_021081965
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020937628   ⟸   XM_021081969
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_020937622   ⟸   XM_021081963
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020937637   ⟸   XM_021081978
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_020937623   ⟸   XM_021081964
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001012296   ⟸   NM_001012296
- UniProtKB: Q5H7B9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000067293   ⟸   ENSSSCT00000079343
RefSeq Acc Id: ENSSSCP00000038011   ⟸   ENSSSCT00000066430
RefSeq Acc Id: ENSSSCP00000050998   ⟸   ENSSSCT00000042562
RefSeq Acc Id: ENSSSCP00000014330   ⟸   ENSSSCT00000014728
RefSeq Acc Id: ENSSSCP00000014329   ⟸   ENSSSCT00000014727
Protein Domains
WD_REPEATS_REGION


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000013481 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070026414 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000014329 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000014330 UniProtKB/TrEMBL
  ENSSSCP00000038011 UniProtKB/TrEMBL
  ENSSSCP00000050998 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000067293 UniProtKB/TrEMBL
  ENSSSCP00070044838 UniProtKB/TrEMBL
  ENSSSCP00070044839 UniProtKB/TrEMBL
  ENSSSCP00070044840 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000014727 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000014728 UniProtKB/TrEMBL
  ENSSSCT00000042562 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000066430 UniProtKB/TrEMBL
  ENSSSCT00000079343 UniProtKB/TrEMBL
  ENSSSCT00070052934 UniProtKB/TrEMBL
  ENSSSCT00070052935 UniProtKB/TrEMBL
  ENSSSCT00070052936 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro Apc4_WD40_dom UniProtKB/TrEMBL
  Cdc20/Fizzy UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report ssc:497234 UniProtKB/TrEMBL
NCBI Gene FZR1 ENTREZGENE
PANTHER PTHR19918 UniProtKB/TrEMBL
Pfam ANAPC4_WD40 UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
PROSITE WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt A0A287A264_PIG UniProtKB/TrEMBL
  A0A4X1VSL5_PIG UniProtKB/TrEMBL
  A0A4X1VT82_PIG UniProtKB/TrEMBL
  A0A4X1VUG0_PIG UniProtKB/TrEMBL
  A0A5G2QZB8_PIG UniProtKB/TrEMBL
  A0A5K1V8L0_PIG UniProtKB/TrEMBL
  F1S7R5_PIG UniProtKB/TrEMBL
  Q5H7B9 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A287B3F2 UniProtKB/TrEMBL
  F1S8E3 UniProtKB/TrEMBL
VGNC ID VGNC:88285 ENTREZGENE