FDPS (farnesyl diphosphate synthase) - Rat Genome Database

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Gene: FDPS (farnesyl diphosphate synthase) Sus scrofa
Analyze
Symbol: FDPS
Name: farnesyl diphosphate synthase
RGD ID: 14288419
Description: ENCODES a protein that exhibits geranyltranstransferase activity (ortholog); INVOLVED IN cellular response to fatty acid (ortholog); farnesyl diphosphate biosynthetic process (ortholog); male gonad development (ortholog); PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); parathyroid carcinoma (ortholog); Porokeratosis 9, Multiple Types (ortholog); FOUND IN mitochondrial matrix (ortholog); peroxisome (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase); farnesyl pyrophosphate synthase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl494,489,215 - 94,518,408 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1494,500,140 - 94,514,820 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24103,291,797 - 103,304,940 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:14681463   PMID:15679890   PMID:17145712  


Genomics

Comparative Map Data
FDPS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl494,489,215 - 94,518,408 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1494,500,140 - 94,514,820 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24103,291,797 - 103,304,940 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FDPS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1155,308,748 - 155,320,666 (+)EnsemblGRCh38hg38GRCh38
GRCh381155,308,801 - 155,320,665 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371155,278,657 - 155,290,456 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361153,545,374 - 153,557,080 (+)NCBINCBI36hg18NCBI36
Build 341152,092,649 - 152,103,529NCBI
Celera1128,351,680 - 128,363,599 (+)NCBI
Cytogenetic Map1q22NCBI
HuRef1126,640,838 - 126,652,759 (+)NCBIHuRef
CHM1_11156,673,976 - 156,685,898 (+)NCBICHM1_1
Fdps
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39389,000,895 - 89,009,274 (-)NCBIGRCm39mm39
GRCm39 Ensembl389,000,895 - 89,009,266 (-)Ensembl
GRCm38389,093,588 - 89,101,967 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl389,093,588 - 89,101,959 (-)EnsemblGRCm38mm10GRCm38
MGSCv37388,897,510 - 88,905,867 (-)NCBIGRCm37mm9NCBIm37
MGSCv36389,179,515 - 89,187,872 (-)NCBImm8
Celera389,132,279 - 89,140,636 (-)NCBICelera
Cytogenetic Map3F1NCBI
cM Map339.01NCBI
Fdps
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22174,497,402 - 174,507,031 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl2174,486,665 - 174,507,776 (-)Ensembl
Rnor_6.02188,403,595 - 188,413,219 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2188,392,858 - 188,413,219 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02207,816,332 - 207,826,348 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42181,138,474 - 181,177,903 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12181,119,007 - 181,128,009 (-)NCBI
Celera2168,441,483 - 168,451,110 (-)NCBICelera
Cytogenetic Map2q34NCBI
Fdps
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555451,757,418 - 1,765,028 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555451,757,090 - 1,765,028 (+)NCBIChiLan1.0ChiLan1.0
FDPS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11134,258,881 - 134,270,237 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1134,258,968 - 134,270,237 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01130,653,316 - 130,665,196 (+)NCBIMhudiblu_PPA_v0panPan3
FDPS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1742,241,086 - 42,250,373 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl742,241,107 - 42,250,225 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha741,731,911 - 41,741,200 (-)NCBI
ROS_Cfam_1.0742,110,187 - 42,119,478 (-)NCBI
UMICH_Zoey_3.1741,890,063 - 41,899,349 (-)NCBI
UNSW_CanFamBas_1.0741,943,839 - 41,953,128 (-)NCBI
UU_Cfam_GSD_1.0742,227,832 - 42,237,121 (-)NCBI
Fdps
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505825,768,903 - 25,778,024 (+)NCBI
SpeTri2.0NW_0049365804,799,354 - 4,808,406 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FDPS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1208,514,311 - 8,526,363 (-)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660387,851,669 - 7,864,161 (-)NCBIVero_WHO_p1.0
Fdps
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624885942,998 - 949,529 (+)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 7 2 4 11 2 1
Below cutoff 3 1 3 1 2 12 2 1 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000007132   ⟹   ENSSSCP00000006940
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl494,489,215 - 94,513,842 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000090341   ⟹   ENSSSCP00000067990
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl494,500,141 - 94,518,408 (-)Ensembl
RefSeq Acc Id: NM_001185131   ⟹   NP_001172060
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1494,500,195 - 94,513,694 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005663310   ⟹   XP_005663367
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1494,500,140 - 94,514,820 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021088556   ⟹   XP_020944215
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1494,500,140 - 94,514,736 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021088557   ⟹   XP_020944216
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1494,500,140 - 94,514,742 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021088559   ⟹   XP_020944218
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1494,500,141 - 94,514,820 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_005663367   ⟸   XM_005663310
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_020944216   ⟸   XM_021088557
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_020944215   ⟸   XM_021088556
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020944218   ⟸   XM_021088559
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: NP_001172060   ⟸   NM_001185131
- Peptide Label: precursor
- UniProtKB: D0G6X4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000067990   ⟸   ENSSSCT00000090341
RefSeq Acc Id: ENSSSCP00000006940   ⟸   ENSSSCT00000007132


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000006512 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070027853 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000006940 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000067990 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00070047472 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000007132 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000090341 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00070055881 UniProtKB/TrEMBL
Gene3D-CATH 1.10.600.10 UniProtKB/TrEMBL
InterPro Isoprenoid_synthase_dom_sf UniProtKB/TrEMBL
  Polyprenyl_synt UniProtKB/TrEMBL
  Polyprenyl_synt_CS UniProtKB/TrEMBL
KEGG Report ssc:100153932 UniProtKB/TrEMBL
NCBI Gene FDPS ENTREZGENE
Pfam polyprenyl_synt UniProtKB/TrEMBL
PROSITE POLYPRENYL_SYNTHASE_1 UniProtKB/TrEMBL
  POLYPRENYL_SYNTHASE_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF48576 UniProtKB/TrEMBL
UniProt A0A4X1VZX0_PIG UniProtKB/TrEMBL
  A0A5G2QST4_PIG UniProtKB/TrEMBL
  D0G6X4 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:88077 ENTREZGENE