CAPN7 (calpain 7) - Rat Genome Database

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Gene: CAPN7 (calpain 7) Sus scrofa
Analyze
Symbol: CAPN7
Name: calpain 7
RGD ID: 14288126
Description: ENCODES a protein that exhibits calcium-dependent cysteine-type endopeptidase activity (inferred); cysteine-type endopeptidase activity (inferred); cysteine-type peptidase activity (inferred); INVOLVED IN positive regulation of epithelial cell migration (inferred); proteolysis (inferred); self proteolysis (inferred); ASSOCIATED WITH 3p deletion syndrome (ortholog); genetic disease (ortholog); FOUND IN centrosome (inferred); cytosol (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: calpain-7
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl132,452,215 - 2,504,581 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1132,452,385 - 2,503,575 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2132,379,271 - 2,430,518 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
centrosome  (IEA)
cytosol  (IEA)
nucleus  (IEA)

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
CAPN7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl132,452,215 - 2,504,581 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1132,452,385 - 2,503,575 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2132,379,271 - 2,430,518 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CAPN7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38315,206,246 - 15,252,916 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl315,206,152 - 15,252,916 (+)EnsemblGRCh38hg38GRCh38
GRCh37315,247,753 - 15,294,423 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36315,222,737 - 15,269,427 (+)NCBINCBI36Build 36hg18NCBI36
Build 34315,222,736 - 15,269,426NCBI
Celera315,185,995 - 15,232,682 (+)NCBICelera
Cytogenetic Map3p25.1NCBI
HuRef315,183,168 - 15,229,881 (+)NCBIHuRef
CHM1_1315,198,625 - 15,245,309 (+)NCBICHM1_1
T2T-CHM13v2.0315,208,655 - 15,255,322 (+)NCBIT2T-CHM13v2.0
Capn7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391431,058,582 - 31,093,944 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1431,058,595 - 31,093,943 (+)EnsemblGRCm39 Ensembl
GRCm381431,336,622 - 31,371,987 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1431,336,638 - 31,371,986 (+)EnsemblGRCm38mm10GRCm38
MGSCv371432,149,910 - 32,185,170 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361430,165,733 - 30,200,993 (+)NCBIMGSCv36mm8
Celera1427,595,408 - 27,630,668 (+)NCBICelera
Cytogenetic Map14BNCBI
cM Map1419.1NCBI
Capn7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8166,552,048 - 6,588,317 (+)NCBIGRCr8
mRatBN7.2166,545,630 - 6,581,908 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl166,545,731 - 6,581,905 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx166,557,942 - 6,594,211 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0167,702,838 - 7,739,107 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0166,564,944 - 6,601,116 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0167,435,541 - 7,472,483 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl167,435,634 - 7,471,807 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0167,371,439 - 7,407,437 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4166,784,270 - 6,820,953 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1166,784,261 - 6,820,261 (+)NCBI
Celera168,607,596 - 8,643,420 (-)NCBICelera
Cytogenetic Map16p16NCBI
Capn7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554302,269,274 - 2,308,713 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554302,269,274 - 2,307,801 (-)NCBIChiLan1.0ChiLan1.0
CAPN7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2215,190,903 - 15,236,985 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1315,195,685 - 15,241,747 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0315,131,774 - 15,177,836 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1315,468,890 - 15,515,528 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl315,468,890 - 15,515,528 (+)Ensemblpanpan1.1panPan2
CAPN7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12327,336,079 - 27,377,584 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2327,336,843 - 27,378,606 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2327,310,053 - 27,351,668 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02327,847,982 - 27,889,616 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12327,537,384 - 27,578,829 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02327,599,118 - 27,640,471 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02327,848,446 - 27,890,014 (-)NCBIUU_Cfam_GSD_1.0
Capn7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118169,974,375 - 170,011,926 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364733,112,951 - 3,150,640 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364733,112,951 - 3,152,963 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CAPN7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11560,050,488 - 60,096,369 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1560,050,606 - 60,095,330 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604133,080,043 - 33,126,578 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Capn7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248224,896,055 - 4,947,514 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CAPN7
2613 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 2 2 3 4 12 2 2 1
Low 8 2 1 2 11 1 2
Below cutoff

Sequence


RefSeq Acc Id: ENSSSCT00000022738   ⟹   ENSSSCP00000021370
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl132,452,215 - 2,504,581 (+)Ensembl
RefSeq Acc Id: NM_001097443   ⟹   NP_001090912
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1132,452,385 - 2,503,575 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001090912   ⟸   NM_001097443
- UniProtKB: A0FKG7 (UniProtKB/Swiss-Prot),   A0A480YTS2 (UniProtKB/TrEMBL),   A0A481AWU0 (UniProtKB/TrEMBL),   I3LBF0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000021370   ⟸   ENSSSCT00000022738
Protein Domains
Calpain catalytic


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000030697 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005035221 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000022738 ENTREZGENE
  ENSSSCT00000022738.4 UniProtKB/TrEMBL
  ENSSSCT00005057031.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.380 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cysteine proteinases UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Phosphotransferase system, lactose/cellobiose-type IIA subunit UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Calpain_cysteine_protease UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Calpain_domain_III UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Calpain_III UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Calpain_III_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIT_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Papain-like_cys_pep_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_C2_calpain_cat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:100037936 UniProtKB/Swiss-Prot
NCBI Gene CAPN7 ENTREZGENE
PANTHER CALPAIN-7 UniProtKB/Swiss-Prot
  CALPAIN-7 UniProtKB/Swiss-Prot
  CALPAIN-7 UniProtKB/TrEMBL
  CALPAIN-7 UniProtKB/TrEMBL
Pfam Calpain_III UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_C2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS CALPAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE CALPAIN_CAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART calpain_III UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CysPc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF116846 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49758 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54001 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A480YTS2 ENTREZGENE
  A0A481AWU0 ENTREZGENE
  A0A8D0K1Y8_PIG UniProtKB/TrEMBL
  A0FKG7 ENTREZGENE
  A0MWE8_PIG UniProtKB/TrEMBL
  A0MWE9_PIG UniProtKB/TrEMBL
  A0MWF0_PIG UniProtKB/TrEMBL
  C0LR98_PIG UniProtKB/TrEMBL
  CAN7_PIG UniProtKB/Swiss-Prot
  I3LBF0 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A480YTS2 UniProtKB/TrEMBL
  A0A481AWU0 UniProtKB/TrEMBL
VGNC ID VGNC:111186 ENTREZGENE