PIGL (phosphatidylinositol glycan anchor biosynthesis class L) - Rat Genome Database

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Gene: PIGL (phosphatidylinositol glycan anchor biosynthesis class L) Sus scrofa
Analyze
Symbol: PIGL
Name: phosphatidylinositol glycan anchor biosynthesis class L
RGD ID: 14284151
Description: ENCODES a protein that exhibits N-acetylglucosaminylphosphatidylinositol deacetylase activity (inferred); INVOLVED IN GPI anchor biosynthetic process (ortholog); ASSOCIATED WITH CHIME syndrome (ortholog); genetic disease (ortholog); hyperphosphatasia with impaired intellectual development syndrome (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1259,201,556 - 59,256,829 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11259,217,267 - 59,256,896 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21262,342,368 - 62,382,439 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:30032202  


Genomics

Comparative Map Data
PIGL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1259,201,556 - 59,256,829 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11259,217,267 - 59,256,896 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21262,342,368 - 62,382,439 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PIGL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381716,217,210 - 16,326,411 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1716,217,191 - 16,351,797 (+)EnsemblGRCh38hg38GRCh38
GRCh371716,120,524 - 16,229,725 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361716,061,234 - 16,170,298 (+)NCBINCBI36Build 36hg18NCBI36
Build 341716,061,260 - 16,170,296NCBI
Celera1716,023,433 - 16,132,500 (+)NCBICelera
Cytogenetic Map17p11.2NCBI
HuRef1715,987,546 - 16,096,166 (+)NCBIHuRef
CHM1_11716,130,315 - 16,239,332 (+)NCBICHM1_1
T2T-CHM13v2.01716,119,521 - 16,254,125 (+)NCBIT2T-CHM13v2.0
Pigl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391162,349,267 - 62,406,863 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1162,349,286 - 62,405,243 (+)EnsemblGRCm39 Ensembl
GRCm381162,458,441 - 62,516,037 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1162,458,460 - 62,514,417 (+)EnsemblGRCm38mm10GRCm38
MGSCv371162,271,962 - 62,327,402 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361162,274,655 - 62,330,095 (+)NCBIMGSCv36mm8
Celera1169,377,657 - 69,433,527 (+)NCBICelera
Cytogenetic Map11B2NCBI
cM Map1138.34NCBI
Pigl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81047,641,478 - 47,699,200 (+)NCBIGRCr8
mRatBN7.21047,142,160 - 47,199,892 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1047,141,780 - 47,200,145 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1051,845,763 - 51,903,705 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01051,336,320 - 51,394,255 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01046,839,726 - 46,897,666 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01048,774,018 - 48,831,848 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1048,773,828 - 48,831,855 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01048,560,437 - 48,618,267 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41048,629,666 - 48,689,128 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11048,642,908 - 48,703,004 (+)NCBI
Celera1046,389,721 - 46,447,273 (+)NCBICelera
Cytogenetic Map10q23NCBI
Pigl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554671,566,494 - 1,645,158 (+)NCBIChiLan1.0ChiLan1.0
PIGL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21956,283,682 - 56,417,860 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11761,097,246 - 61,229,497 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01735,122,347 - 35,252,800 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A110,417,772 - 110,523,985 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A110,417,770 - 110,546,387 (+)Ensemblpanpan1.1panPan2
PIGL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1539,601,288 - 39,687,125 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl539,601,291 - 39,686,908 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha539,747,720 - 39,833,502 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0539,711,630 - 39,797,577 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl539,711,924 - 39,797,068 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1539,683,300 - 39,769,219 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0539,628,568 - 39,714,511 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0539,820,769 - 39,906,365 (-)NCBIUU_Cfam_GSD_1.0
Pigl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560259,431,040 - 59,523,768 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936821288,026 - 381,172 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936821290,240 - 381,126 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PIGL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11615,340,548 - 15,351,677 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660595,518,598 - 5,629,387 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pigl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248774,117,075 - 4,202,616 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248774,078,752 - 4,202,024 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PIGL
1769 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 9 4 3 5 2 23 2 3 3
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000059179   ⟹   ENSSSCP00000038291
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1259,217,922 - 59,256,829 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000083555   ⟹   ENSSSCP00000063676
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1259,201,556 - 59,256,818 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000086694   ⟹   ENSSSCP00000061709
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1259,218,251 - 59,256,829 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000089230   ⟹   ENSSSCP00000073161
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1259,215,551 - 59,256,820 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000104908   ⟹   ENSSSCP00000076604
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1259,215,551 - 59,256,820 (-)Ensembl
RefSeq Acc Id: XM_003132024   ⟹   XP_003132072
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11259,217,267 - 59,256,883 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013980387   ⟹   XP_013835841
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11259,242,730 - 59,256,896 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013980388   ⟹   XP_013835842
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11259,217,267 - 59,248,852 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_003132072   ⟸   XM_003132024
- Peptide Label: isoform X1
- UniProtKB: A0A4X1SRG8 (UniProtKB/TrEMBL),   A0A5G2RER5 (UniProtKB/TrEMBL),   A0A8D1AQP2 (UniProtKB/TrEMBL),   A0A8D1NX69 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013835842   ⟸   XM_013980388
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_013835841   ⟸   XM_013980387
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSSSCP00000063676   ⟸   ENSSSCT00000083555
RefSeq Acc Id: ENSSSCP00000073161   ⟸   ENSSSCT00000089230
RefSeq Acc Id: ENSSSCP00000038291   ⟸   ENSSSCT00000059179
RefSeq Acc Id: ENSSSCP00000061709   ⟸   ENSSSCT00000086694
RefSeq Acc Id: ENSSSCP00000076604   ⟸   ENSSSCT00000104908


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000035103 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00035065163 UniProtKB/TrEMBL
  ENSSSCG00045028485 UniProtKB/TrEMBL
  ENSSSCG00050077265 UniProtKB/TrEMBL
  ENSSSCG00070003228 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000059179.3 UniProtKB/TrEMBL
  ENSSSCT00000083555.2 UniProtKB/TrEMBL
  ENSSSCT00000086694.2 UniProtKB/TrEMBL
  ENSSSCT00000089230 ENTREZGENE
  ENSSSCT00000089230.2 UniProtKB/TrEMBL
  ENSSSCT00000104908.1 UniProtKB/TrEMBL
  ENSSSCT00035087757.1 UniProtKB/TrEMBL
  ENSSSCT00045048732.1 UniProtKB/TrEMBL
  ENSSSCT00050106395.1 UniProtKB/TrEMBL
  ENSSSCT00070006096.1 UniProtKB/TrEMBL
  ENSSSCT00070006105.1 UniProtKB/TrEMBL
  ENSSSCT00070006111.1 UniProtKB/TrEMBL
  ENSSSCT00070006117.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.10320 UniProtKB/TrEMBL
InterPro GlcNAc_PI_deacetylase-related UniProtKB/TrEMBL
  LmbE-like_dom_sf UniProtKB/TrEMBL
KEGG Report ssc:100523821 UniProtKB/TrEMBL
NCBI Gene PIGL ENTREZGENE
PANTHER PTHR12993 UniProtKB/TrEMBL
  PTHR12993:SF11 UniProtKB/TrEMBL
Pfam PIG-L UniProtKB/TrEMBL
Superfamily-SCOP SSF102588 UniProtKB/TrEMBL
UniProt A0A287A2Y9_PIG UniProtKB/TrEMBL
  A0A4X1SQJ5_PIG UniProtKB/TrEMBL
  A0A4X1SQK8_PIG UniProtKB/TrEMBL
  A0A4X1SRG8 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1SS30_PIG UniProtKB/TrEMBL
  A0A5G2QC94_PIG UniProtKB/TrEMBL
  A0A5G2QIF0_PIG UniProtKB/TrEMBL
  A0A5G2RER5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1AQP2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1NX69 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FBA6_PIG UniProtKB/TrEMBL
VGNC ID VGNC:91424 ENTREZGENE