EOGT (EGF domain specific O-linked N-acetylglucosamine transferase) - Rat Genome Database

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Gene: EOGT (EGF domain specific O-linked N-acetylglucosamine transferase) Sus scrofa
Analyze
Symbol: EOGT
Name: EGF domain specific O-linked N-acetylglucosamine transferase
RGD ID: 14281166
Description: ENCODES a protein that exhibits glycosyltransferase activity (inferred); protein O-acetylglucosaminyltransferase activity (inferred); INVOLVED IN protein O-GlcNAcylation via threonine (inferred); protein O-linked glycosylation (inferred); ASSOCIATED WITH Adams-Oliver syndrome (ortholog); Adams-Oliver Syndrome 4 (ortholog); genetic disease (ortholog); FOUND IN endoplasmic reticulum lumen (inferred)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: EGF domain-specific O-linked N-acetylglucosamine transferase; OGT; secreted O-linked N-acetylglucosamine transferase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1350,396,629 - 50,436,199 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11350,396,625 - 50,436,218 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21355,478,584 - 55,518,845 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:25538681   PMID:30032202  


Genomics

Comparative Map Data
EOGT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1350,396,629 - 50,436,199 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11350,396,625 - 50,436,218 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21355,478,584 - 55,518,845 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EOGT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38368,975,225 - 69,013,684 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl368,975,217 - 69,013,684 (-)EnsemblGRCh38hg38GRCh38
GRCh37369,024,376 - 69,062,835 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36369,107,058 - 69,145,464 (-)NCBINCBI36Build 36hg18NCBI36
Celera368,952,460 - 68,990,886 (-)NCBICelera
Cytogenetic Map3p14.1NCBI
HuRef369,025,405 - 69,064,100 (-)NCBIHuRef
CHM1_1368,967,096 - 69,014,262 (-)NCBICHM1_1
T2T-CHM13v2.0369,011,970 - 69,050,451 (-)NCBIT2T-CHM13v2.0
Eogt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39697,086,977 - 97,128,445 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl697,086,985 - 97,126,143 (-)EnsemblGRCm39 Ensembl
GRCm38697,110,016 - 97,151,484 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl697,110,024 - 97,149,182 (-)EnsemblGRCm38mm10GRCm38
MGSCv37697,060,938 - 97,098,877 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36697,076,407 - 97,114,346 (-)NCBIMGSCv36mm8
Celera698,971,682 - 99,007,964 (-)NCBICelera
Cytogenetic Map6D3NCBI
cM Map644.88NCBI
Eogt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84131,275,587 - 131,313,243 (-)NCBIGRCr8
mRatBN7.24129,718,897 - 129,756,558 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4129,718,901 - 129,756,445 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4135,145,672 - 135,181,170 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04130,926,712 - 130,962,211 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04129,544,671 - 129,580,156 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04129,477,779 - 129,515,435 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4129,477,807 - 129,515,435 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04193,981,263 - 194,019,171 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44131,833,304 - 131,869,461 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14132,078,144 - 132,114,302 (-)NCBI
Celera4118,596,974 - 118,632,628 (-)NCBICelera
Cytogenetic Map4q34NCBI
Eogt
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542118,846,420 - 18,879,985 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542118,845,626 - 18,879,008 (+)NCBIChiLan1.0ChiLan1.0
EOGT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2268,929,882 - 68,969,526 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1368,935,557 - 68,975,490 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0368,910,100 - 68,950,816 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1370,277,052 - 70,317,471 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl370,277,450 - 70,317,465 (-)Ensemblpanpan1.1panPan2
EOGT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12022,722,142 - 22,757,188 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2022,722,919 - 22,757,136 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2022,700,472 - 22,730,866 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02022,748,283 - 22,784,106 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2022,748,323 - 22,784,097 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12022,445,490 - 22,476,039 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02022,788,996 - 22,819,398 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02022,859,033 - 22,889,647 (+)NCBIUU_Cfam_GSD_1.0
Eogt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049421,608,350 - 1,637,435 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366031,612,510 - 1,636,291 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366031,608,173 - 1,638,052 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EOGT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12230,002,069 - 30,040,851 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2229,999,914 - 30,035,877 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041136,752,774 - 136,790,465 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eogt
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247733,534,833 - 3,582,752 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247733,536,059 - 3,582,847 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in EOGT
1424 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 3 2 1 5 1 2 2 3
Low 7 2 2 2 22 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000012589   ⟹   ENSSSCP00000012260
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1350,396,629 - 50,436,199 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000076062   ⟹   ENSSSCP00000064724
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1350,396,629 - 50,436,199 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000077875   ⟹   ENSSSCP00000067430
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1350,396,629 - 50,436,199 (-)Ensembl
RefSeq Acc Id: NM_001315674   ⟹   NP_001302603
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11350,398,853 - 50,432,555 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021068244   ⟹   XP_020923903
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11350,396,625 - 50,436,218 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020923903   ⟸   XM_021068244
- Peptide Label: isoform X1
- UniProtKB: F1SFQ3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001302603   ⟸   NM_001315674
- Peptide Label: precursor
- UniProtKB: K9MA89 (UniProtKB/TrEMBL),   A0A481A6F2 (UniProtKB/TrEMBL),   A0A4X1V838 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000064724   ⟸   ENSSSCT00000076062
RefSeq Acc Id: ENSSSCP00000012260   ⟸   ENSSSCT00000012589
RefSeq Acc Id: ENSSSCP00000067430   ⟸   ENSSSCT00000077875
Protein Domains
Glycosyltransferase 61 catalytic


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000011504 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00030039342 UniProtKB/TrEMBL
  ENSSSCG00040004078 UniProtKB/TrEMBL
  ENSSSCG00045017724 UniProtKB/TrEMBL
  ENSSSCG00050022608 UniProtKB/TrEMBL
  ENSSSCG00060027497 UniProtKB/TrEMBL
  ENSSSCG00065077755 UniProtKB/TrEMBL
  ENSSSCG00070023197 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000012589 ENTREZGENE
  ENSSSCT00000012589.5 UniProtKB/TrEMBL
  ENSSSCT00000076062.1 UniProtKB/TrEMBL
  ENSSSCT00000077875.2 UniProtKB/TrEMBL
  ENSSSCT00030054831.1 UniProtKB/TrEMBL
  ENSSSCT00040005235.1 UniProtKB/TrEMBL
  ENSSSCT00045030213.1 UniProtKB/TrEMBL
  ENSSSCT00050030546.1 UniProtKB/TrEMBL
  ENSSSCT00060037245.1 UniProtKB/TrEMBL
  ENSSSCT00065107660.1 UniProtKB/TrEMBL
  ENSSSCT00070046251.1 UniProtKB/TrEMBL
  ENSSSCT00070046254.1 UniProtKB/TrEMBL
  ENSSSCT00070046257.1 UniProtKB/TrEMBL
  ENSSSCT00070046262.1 UniProtKB/TrEMBL
InterPro Glyco_transf_61_cat UniProtKB/TrEMBL
  Glycosyltransferase_61 UniProtKB/TrEMBL
KEGG Report ssc:100155485 UniProtKB/TrEMBL
NCBI Gene EOGT ENTREZGENE
PANTHER EGF DOMAIN-SPECIFIC O-LINKED N-ACETYLGLUCOSAMINE TRANSFERASE UniProtKB/TrEMBL
  PTHR20961 UniProtKB/TrEMBL
Pfam DUF563 UniProtKB/TrEMBL
UniProt A0A481A6F2 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1V838 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2R2G1_PIG UniProtKB/TrEMBL
  A0A5G2R9Z5_PIG UniProtKB/TrEMBL
  F1SFQ3 ENTREZGENE, UniProtKB/TrEMBL
  K9MA89 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:87718 ENTREZGENE