LOC100522421 (aldehyde dehydrogenase family 3 member B2-like) - Rat Genome Database

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Gene: LOC100522421 (aldehyde dehydrogenase family 3 member B2-like) Sus scrofa
Analyze
Symbol: LOC100522421 (Ensembl: ALDH3B2)
Name: aldehyde dehydrogenase family 3 member B2-like (Ensembl:aldehyde dehydrogenase 3 family member B2)
RGD ID: 14279702
Description: ENCODES a protein that exhibits aldehyde dehydrogenase [NAD(P)+] activity (ortholog); INVOLVED IN cellular aldehyde metabolic process (inferred); ASSOCIATED WITH Aicardi-Goutieres Syndrome 3 (ortholog); autism spectrum disorder (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl24,920,068 - 4,928,554 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.124,910,123 - 4,928,559 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.223,561,218 - 3,568,995 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LOC100522421
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl24,920,068 - 4,928,554 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.124,910,123 - 4,928,559 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.223,561,218 - 3,568,995 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ALDH3B2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381167,662,155 - 67,681,252 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1167,662,155 - 67,681,224 (-)EnsemblGRCh38hg38GRCh38
GRCh371167,429,626 - 67,448,723 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361167,186,209 - 67,205,261 (-)NCBINCBI36Build 36hg18NCBI36
Build 341167,186,212 - 67,198,641NCBI
Celera1164,764,391 - 64,781,968 (-)NCBICelera
Cytogenetic Map11q13.2NCBI
HuRef1163,759,207 - 63,777,253 (-)NCBIHuRef
CHM1_11167,312,897 - 67,331,790 (-)NCBICHM1_1
T2T-CHM13v2.01167,657,144 - 67,676,182 (-)NCBIT2T-CHM13v2.0
Aldh3b2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39194,022,328 - 4,031,665 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl194,022,328 - 4,031,646 (+)EnsemblGRCm39 Ensembl
GRCm38193,972,328 - 3,981,665 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl193,972,328 - 3,981,646 (+)EnsemblGRCm38mm10GRCm38
MGSCv37193,972,328 - 3,981,665 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36193,972,328 - 3,981,665 (+)NCBIMGSCv36mm8
Celera193,847,868 - 3,852,718 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map193.69NCBI
Aldh3b2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81210,679,749 - 210,694,187 (+)NCBIGRCr8
mRatBN7.21201,250,260 - 201,264,699 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1201,253,157 - 201,264,705 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01219,215,023 - 219,218,488 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01226,085,121 - 226,089,139 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41206,549,529 - 206,553,424 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1198,805,403 - 198,809,760 (+)NCBICelera
Cytogenetic Map1q43NCBI
ALDH3B2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2968,890,840 - 68,904,996 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11169,933,531 - 69,948,233 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01163,022,475 - 63,042,873 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11166,334,197 - 66,351,931 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1166,334,197 - 66,345,987 (-)Ensemblpanpan1.1panPan2
LOC611806
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11849,856,341 - 49,860,263 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1849,853,737 - 49,859,927 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1848,466,297 - 48,469,251 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01850,778,067 - 50,780,832 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1850,778,093 - 50,781,041 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11849,991,474 - 49,994,487 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01849,566,517 - 49,569,262 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01850,359,886 - 50,362,899 (+)NCBIUU_Cfam_GSD_1.0
ALDH3B2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.116,594,240 - 6,607,230 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666038103,872,979 - 103,886,365 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aldh3b2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476718,901,372 - 18,904,686 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476718,901,351 - 18,906,618 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in LOC100522421
870 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system hemolymphoid system nervous system reproductive system respiratory system
High
Medium
Low 1 2 3
Below cutoff 4 5

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000014101   ⟹   ENSSSCP00000013715
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl24,920,068 - 4,928,554 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000093399   ⟹   ENSSSCP00000075160
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl24,923,345 - 4,928,554 (+)Ensembl
RefSeq Acc Id: XM_013994017   ⟹   XP_013849471
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.124,920,613 - 4,928,559 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021082735   ⟹   XP_020938394
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.124,919,952 - 4,928,559 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021082736   ⟹   XP_020938395
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.124,910,123 - 4,928,559 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021082737   ⟹   XP_020938396
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.124,912,539 - 4,928,559 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021082738   ⟹   XP_020938397
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.124,921,393 - 4,928,559 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020938395   ⟸   XM_021082736
- Peptide Label: isoform X2
- UniProtKB: A0A8W4F8L5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020938396   ⟸   XM_021082737
- Peptide Label: isoform X2
- UniProtKB: A0A8W4F8L5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020938394   ⟸   XM_021082735
- Peptide Label: isoform X2
- UniProtKB: A0A8W4F8L5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013849471   ⟸   XM_013994017
- Peptide Label: isoform X1
- UniProtKB: V9GZ89 (UniProtKB/TrEMBL),   A0A8D1ASQ4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020938397   ⟸   XM_021082738
- Peptide Label: isoform X2
- UniProtKB: A0A8W4F8L5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000013715   ⟸   ENSSSCT00000014101
RefSeq Acc Id: ENSSSCP00000075160   ⟸   ENSSSCT00000093399
Protein Domains
Aldehyde dehydrogenase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000026349 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00030004459 UniProtKB/TrEMBL
  ENSSSCG00035061451 UniProtKB/TrEMBL
  ENSSSCG00040065036 UniProtKB/TrEMBL
  ENSSSCG00045002284 UniProtKB/TrEMBL
  ENSSSCG00050078752 UniProtKB/TrEMBL
  ENSSSCG00055028554 UniProtKB/TrEMBL
  ENSSSCG00060055994 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000014101 ENTREZGENE
  ENSSSCT00000014101.5 UniProtKB/TrEMBL
  ENSSSCT00000093399 ENTREZGENE
  ENSSSCT00000093399.1 UniProtKB/TrEMBL
  ENSSSCT00030005964.1 UniProtKB/TrEMBL
  ENSSSCT00030005970.1 UniProtKB/TrEMBL
  ENSSSCT00035082587.1 UniProtKB/TrEMBL
  ENSSSCT00035082595.1 UniProtKB/TrEMBL
  ENSSSCT00040089106.1 UniProtKB/TrEMBL
  ENSSSCT00040089225.1 UniProtKB/TrEMBL
  ENSSSCT00045003616.1 UniProtKB/TrEMBL
  ENSSSCT00045003634.1 UniProtKB/TrEMBL
  ENSSSCT00050108655.1 UniProtKB/TrEMBL
  ENSSSCT00050108664.1 UniProtKB/TrEMBL
  ENSSSCT00055056689.1 UniProtKB/TrEMBL
  ENSSSCT00055056751.1 UniProtKB/TrEMBL
  ENSSSCT00060076302.1 UniProtKB/TrEMBL
  ENSSSCT00060076318.1 UniProtKB/TrEMBL
InterPro Ald_DH/histidinol_DH UniProtKB/TrEMBL
  Ald_DH_C UniProtKB/TrEMBL
  Ald_DH_CS_CYS UniProtKB/TrEMBL
  Ald_DH_CS_GLU UniProtKB/TrEMBL
  Ald_DH_N UniProtKB/TrEMBL
  Aldehyde_DH_dom UniProtKB/TrEMBL
  Aldehyde_DH_NAD(P) UniProtKB/TrEMBL
NCBI Gene LOC100522421 ENTREZGENE
PANTHER ALDEHYDE DEHYDROGENASE FAMILY 3 MEMBER B1 UniProtKB/TrEMBL
  PTHR43570 UniProtKB/TrEMBL
Pfam Aldedh UniProtKB/TrEMBL
PIRSF ALDH UniProtKB/TrEMBL
PROSITE ALDEHYDE_DEHYDR_CYS UniProtKB/TrEMBL
  ALDEHYDE_DEHYDR_GLU UniProtKB/TrEMBL
Superfamily-SCOP SSF53720 UniProtKB/TrEMBL
UniProt A0A8D0V972_PIG UniProtKB/TrEMBL
  A0A8D0V9F0_PIG UniProtKB/TrEMBL
  A0A8D1ASQ4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1FK12_PIG UniProtKB/TrEMBL
  A0A8D1GJ13_PIG UniProtKB/TrEMBL
  A0A8D1GL66_PIG UniProtKB/TrEMBL
  A0A8D1KJ25_PIG UniProtKB/TrEMBL
  A0A8D1W3K7_PIG UniProtKB/TrEMBL
  A0A8W4F8L5 ENTREZGENE, UniProtKB/TrEMBL
  V9GZ89 ENTREZGENE, UniProtKB/TrEMBL