SLC26A8 (solute carrier family 26 member 8) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: SLC26A8 (solute carrier family 26 member 8) Sus scrofa
Analyze
Symbol: SLC26A8
Name: solute carrier family 26 member 8
RGD ID: 14279110
Description: ENCODES a protein that exhibits bicarbonate transmembrane transporter activity (inferred); chloride channel activity (inferred); chloride transmembrane transporter activity (inferred); INVOLVED IN bicarbonate transport (inferred); cell differentiation (inferred); chloride transmembrane transport (inferred); ASSOCIATED WITH genetic disease (ortholog); proteasome-associated autoinflammatory syndrome 1 (ortholog); schizophrenia (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); sperm annulus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: testis anion transporter 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl731,722,103 - 31,791,802 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1731,722,409 - 31,791,620 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2736,660,015 - 36,725,721 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SLC26A8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl731,722,103 - 31,791,802 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1731,722,409 - 31,791,620 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2736,660,015 - 36,725,721 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC26A8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38635,943,516 - 36,024,641 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl635,943,516 - 36,024,868 (-)EnsemblGRCh38hg38GRCh38
GRCh37635,911,293 - 35,992,418 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36636,019,271 - 36,100,355 (-)NCBINCBI36Build 36hg18NCBI36
Build 34636,019,275 - 36,100,248NCBI
Celera637,465,857 - 37,546,973 (-)NCBICelera
Cytogenetic Map6p21.31NCBI
HuRef635,631,132 - 35,712,425 (-)NCBIHuRef
CHM1_1635,913,031 - 35,994,194 (-)NCBICHM1_1
T2T-CHM13v2.0635,763,833 - 35,844,951 (-)NCBIT2T-CHM13v2.0
Slc26a8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391728,856,757 - 28,910,242 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1728,856,757 - 28,909,207 (-)EnsemblGRCm39 Ensembl
GRCm381728,637,779 - 28,691,273 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1728,637,783 - 28,690,233 (-)EnsemblGRCm38mm10GRCm38
MGSCv371728,773,937 - 28,826,932 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361728,377,246 - 28,417,576 (-)NCBIMGSCv36mm8
Celera1729,192,614 - 29,244,985 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1714.82NCBI
Slc26a8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8206,687,207 - 6,751,184 (-)NCBIGRCr8
mRatBN7.2206,686,206 - 6,749,478 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl206,697,723 - 6,749,478 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx207,410,384 - 7,462,124 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0206,772,225 - 6,823,971 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0207,253,123 - 7,305,327 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0205,870,714 - 5,933,151 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,881,462 - 5,931,648 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0207,916,755 - 7,967,148 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4206,898,665 - 6,937,594 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1206,886,712 - 6,939,187 (-)NCBI
Celera208,242,917 - 8,305,701 (-)NCBICelera
Cytogenetic Map20p12NCBI
Slc26a8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554373,741,284 - 3,811,819 (-)NCBIChiLan1.0ChiLan1.0
SLC26A8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2550,408,385 - 50,490,393 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1646,277,982 - 46,359,951 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0635,502,875 - 35,584,146 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1636,705,860 - 36,785,610 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl636,705,860 - 36,785,610 (-)Ensemblpanpan1.1panPan2
SLC26A8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1125,059,267 - 5,145,387 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl125,060,306 - 5,135,677 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha125,080,039 - 5,165,345 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0125,408,442 - 5,493,141 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl125,408,211 - 5,483,212 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1125,062,493 - 5,147,808 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0125,142,535 - 5,227,099 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0125,243,004 - 5,327,100 (-)NCBIUU_Cfam_GSD_1.0
Slc26a8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494640,580,630 - 40,648,654 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647623,315,902 - 23,379,260 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647623,311,740 - 23,380,119 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC26A8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11736,097,458 - 36,175,638 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1736,103,139 - 36,175,459 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604435,892,285 - 35,967,132 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc26a8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475421,608,000 - 21,667,083 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475421,607,197 - 21,667,484 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SLC26A8
1849 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system nervous system renal system reproductive system respiratory system
High
Medium
Low 1
Below cutoff 2 2 1 4 10 1 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000001733   ⟹   ENSSSCP00000001689
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl731,722,452 - 31,791,802 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000050404   ⟹   ENSSSCP00000044726
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl731,722,103 - 31,791,802 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000070620   ⟹   ENSSSCP00000071896
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl731,722,103 - 31,791,802 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000085099   ⟹   ENSSSCP00000067977
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl731,729,007 - 31,791,802 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000098464   ⟹   ENSSSCP00000077542
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl731,724,706 - 31,780,546 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000104919   ⟹   ENSSSCP00000075800
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl731,724,306 - 31,780,546 (-)Ensembl
RefSeq Acc Id: XM_003356617   ⟹   XP_003356665
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1731,722,409 - 31,791,620 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_003356665   ⟸   XM_003356617
- UniProtKB: A0A287AL46 (UniProtKB/TrEMBL),   A0A8D0QMH9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000044726   ⟸   ENSSSCT00000050404
RefSeq Acc Id: ENSSSCP00000001689   ⟸   ENSSSCT00000001733
RefSeq Acc Id: ENSSSCP00000067977   ⟸   ENSSSCT00000085099
RefSeq Acc Id: ENSSSCP00000071896   ⟸   ENSSSCT00000070620
RefSeq Acc Id: ENSSSCP00000075800   ⟸   ENSSSCT00000104919
RefSeq Acc Id: ENSSSCP00000077542   ⟸   ENSSSCT00000098464
Protein Domains
SLC26A/SulP transporter   STAS


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000001555 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025006614 UniProtKB/TrEMBL
  ENSSSCG00070004499 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000001733.5 UniProtKB/TrEMBL
  ENSSSCT00000050404 ENTREZGENE
  ENSSSCT00000050404.3 UniProtKB/TrEMBL
  ENSSSCT00000070620.2 UniProtKB/TrEMBL
  ENSSSCT00000085099.2 UniProtKB/TrEMBL
  ENSSSCT00000098464.1 UniProtKB/TrEMBL
  ENSSSCT00000104919.1 UniProtKB/TrEMBL
  ENSSSCT00025008741.1 UniProtKB/TrEMBL
  ENSSSCT00070008489.1 UniProtKB/TrEMBL
  ENSSSCT00070008495.1 UniProtKB/TrEMBL
  ENSSSCT00070008521.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.750.24 UniProtKB/TrEMBL
InterPro SLC26A/SulP_dom UniProtKB/TrEMBL
  SLC26A/SulP_fam UniProtKB/TrEMBL
  STAS_dom UniProtKB/TrEMBL
  STAS_dom_sf UniProtKB/TrEMBL
NCBI Gene SLC26A8 ENTREZGENE
PANTHER PTHR11814 UniProtKB/TrEMBL
  PTHR11814:SF11 UniProtKB/TrEMBL
Pfam STAS UniProtKB/TrEMBL
  Sulfate_transp UniProtKB/TrEMBL
PROSITE STAS UniProtKB/TrEMBL
Superfamily-SCOP SSF52091 UniProtKB/TrEMBL
UniProt A0A287AL46 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1SVB4_PIG UniProtKB/TrEMBL
  A0A4X1SVT3_PIG UniProtKB/TrEMBL
  A0A5G2QT17_PIG UniProtKB/TrEMBL
  A0A5G2R483_PIG UniProtKB/TrEMBL
  A0A8D0QMH9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FAD7_PIG UniProtKB/TrEMBL
  A0A8W4FE56_PIG UniProtKB/TrEMBL
  F1RYX6_PIG UniProtKB/TrEMBL
VGNC ID VGNC:93033 ENTREZGENE