DACT3 (dishevelled binding antagonist of beta catenin 3) - Rat Genome Database
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Gene: DACT3 (dishevelled binding antagonist of beta catenin 3) Sus scrofa
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Symbol: DACT3
Name: dishevelled binding antagonist of beta catenin 3
RGD ID: 14274913
Description: ENCODES a protein that exhibits delta-catenin binding (ortholog); identical protein binding (ortholog); protein kinase A binding (ortholog); INVOLVED IN negative regulation of canonical Wnt signaling pathway (ortholog); negative regulation of epithelial to mesenchymal transition (ortholog); negative regulation of Wnt signaling pathway (ortholog); ASSOCIATED WITH intellectual disability (ortholog); polycystic ovary syndrome (ortholog); Walker-Warburg syndrome (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: dapper homolog 3; dapper, antagonist of beta-catenin, homolog 3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl652,543,161 - 52,554,082 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1652,543,737 - 52,554,258 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2647,864,372 - 47,874,835 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA,ISO)

Molecular Function

References

Genomics

Comparative Map Data
DACT3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl652,543,161 - 52,554,082 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1652,543,737 - 52,554,258 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2647,864,372 - 47,874,835 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DACT3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1946,647,551 - 46,661,182 (-)EnsemblGRCh38hg38GRCh38
GRCh381946,647,551 - 46,661,182 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371947,150,869 - 47,164,395 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh371947,150,808 - 47,164,439 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361951,842,709 - 51,849,754 (-)NCBINCBI36hg18NCBI36
Celera1943,954,390 - 43,967,921 (-)NCBI
Cytogenetic Map19q13.32NCBI
HuRef1943,575,796 - 43,589,524 (-)NCBIHuRef
CHM1_11947,152,671 - 47,166,253 (-)NCBICHM1_1
Dact3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39716,609,242 - 16,621,226 (+)NCBIGRCm39mm39
GRCm38716,875,317 - 16,887,301 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl716,875,317 - 16,887,462 (+)EnsemblGRCm38mm10GRCm38
MGSCv37717,460,666 - 17,472,650 (+)NCBIGRCm37mm9NCBIm37
MGSCv36717,460,666 - 17,472,650 (+)NCBImm8
Celera714,081,734 - 14,093,719 (+)NCBICelera
Cytogenetic Map7A2NCBI
Dact3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2177,546,900 - 77,558,631 (+)NCBI
Rnor_6.0 Ensembl178,800,754 - 78,812,483 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0178,800,754 - 78,812,483 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0180,048,066 - 80,059,888 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4177,201,808 - 77,213,537 (+)NCBIRGSC3.4rn4RGSC3.4
Celera172,031,999 - 72,043,732 (+)NCBICelera
Cytogenetic Map1q21NCBI
DACT3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11952,168,739 - 52,182,015 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01943,639,921 - 43,653,473 (-)NCBIMhudiblu_PPA_v0panPan3
DACT3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1109,248,556 - 109,255,975 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11109,247,743 - 109,264,655 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dact3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936664505,356 - 514,313 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DACT3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1640,003,475 - 40,016,690 (-)NCBI
ChlSab1.1 Ensembl640,004,348 - 40,016,621 (-)Ensembl
Dact3
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248326,920,984 - 6,930,391 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 2
Low 6 2 3 4 1 21 3
Below cutoff 4 2 1 1 2 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000023724   ⟹   ENSSSCP00000024577
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl652,543,161 - 52,554,082 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000072608   ⟹   ENSSSCP00000073744
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl652,543,161 - 52,554,082 (-)Ensembl
RefSeq Acc Id: XM_003355955   ⟹   XP_003356003
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1652,543,737 - 52,554,258 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003356003 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003356003   ⟸   XM_003355955
- UniProtKB: I3LKG3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000073744   ⟸   ENSSSCT00000072608
RefSeq Acc Id: ENSSSCP00000024577   ⟸   ENSSSCT00000023724


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000022280 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000024577 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000073744 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000023724 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000072608 UniProtKB/TrEMBL
InterPro Dact3 UniProtKB/TrEMBL
  Dapper UniProtKB/TrEMBL
KEGG Report ssc:100622612 UniProtKB/TrEMBL
NCBI Gene DACT3 ENTREZGENE
PANTHER PTHR15919 UniProtKB/TrEMBL
  PTHR15919:SF1 UniProtKB/TrEMBL
Pfam Dapper UniProtKB/TrEMBL
UniProt A0A5G2RME6_PIG UniProtKB/TrEMBL
  I3LKG3 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:87149 ENTREZGENE