CERK (ceramide kinase) - Rat Genome Database

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Gene: CERK (ceramide kinase) Sus scrofa
Analyze
Symbol: CERK
Name: ceramide kinase
RGD ID: 14274847
Description: ENCODES a protein that exhibits ATP binding (inferred); ceramide kinase activity (inferred); kinase activity (inferred); INVOLVED IN ceramide metabolic process (inferred); lipid metabolic process (inferred); PARTICIPATES IN Fabry disease pathway; Gaucher's disease pathway; Krabbe disease pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN cytoplasm (inferred); membrane (inferred); plasma membrane (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl52,818,784 - 2,870,195 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.152,818,738 - 2,870,200 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074  


Genomics

Comparative Map Data
CERK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl52,818,784 - 2,870,195 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.152,818,738 - 2,870,200 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CERK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382246,684,410 - 46,738,252 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2246,684,410 - 46,738,267 (-)Ensemblhg38GRCh38
GRCh372247,080,307 - 47,134,149 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362245,458,971 - 45,512,816 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342245,400,826 - 45,406,632NCBI
Celera2230,995,999 - 31,049,854 (-)NCBICelera
Cytogenetic Map22q13.31NCBI
HuRef2230,025,258 - 30,079,178 (-)NCBIHuRef
CHM1_12247,039,226 - 47,093,493 (-)NCBICHM1_1
T2T-CHM13v2.02247,172,367 - 47,226,215 (-)NCBIT2T-CHM13v2.0
Cerk
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391586,023,302 - 86,070,537 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1586,023,329 - 86,070,342 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381586,139,101 - 86,186,259 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1586,139,128 - 86,186,141 (-)Ensemblmm10GRCm38
MGSCv371585,969,531 - 86,016,571 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361585,966,895 - 86,013,907 (-)NCBIMGSCv36mm8
MGSCv361586,937,923 - 86,985,654 (-)NCBIMGSCv36mm8
Celera1588,281,909 - 88,328,692 (-)NCBICelera
Cytogenetic Map15E2NCBI
cM Map1540.52NCBI
Cerk
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87119,105,674 - 119,149,885 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7119,105,674 - 119,148,570 (-)EnsemblGRCr8
mRatBN7.27117,225,855 - 117,269,436 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7117,225,855 - 117,268,759 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7118,977,337 - 119,020,251 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07121,202,971 - 121,245,883 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07121,172,546 - 121,215,466 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07127,015,162 - 127,058,056 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7127,015,162 - 127,058,056 (-)Ensemblrn6Rnor6.0
Rnor_5.07126,726,021 - 126,768,650 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47124,139,137 - 124,182,070 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7113,516,253 - 113,558,934 (-)NCBICelera
RGSC_v3.17124,173,366 - 124,216,042 (-)NCBI
Cytogenetic Map7q34NCBI
Cerk
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541330,660,593 - 30,679,674 (-)Ensembl
ChiLan1.0NW_00495541330,658,472 - 30,693,948 (-)NCBIChiLan1.0ChiLan1.0
CERK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22356,524,324 - 56,580,132 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12259,215,963 - 59,271,769 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02226,849,865 - 26,905,545 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12245,749,887 - 45,786,570 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2245,749,887 - 45,786,570 (-)EnsemblpanPan2panpan1.1
CERK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11019,560,125 - 19,601,223 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1019,556,087 - 19,598,954 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1019,480,876 - 19,522,720 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01020,294,959 - 20,336,847 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1020,294,760 - 20,336,829 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11020,013,088 - 20,054,908 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01020,325,241 - 20,367,020 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01020,507,050 - 20,548,676 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cerk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049453,304,236 - 3,346,264 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366293,304,236 - 3,344,136 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366293,304,236 - 3,346,264 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CERK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11929,183,324 - 29,236,857 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604596,276,619 - 96,355,869 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cerk
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247523,285,637 - 3,326,738 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247523,285,649 - 3,328,131 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Cerk
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11255,482,761 - 255,525,447 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in CERK
2074 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000036935   ⟹   ENSSSCP00000056718
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl52,818,784 - 2,870,195 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000061800   ⟹   ENSSSCP00000039683
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl52,818,903 - 2,870,196 (+)Ensembl
RefSeq Acc Id: XM_021093094   ⟹   XP_020948753
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.152,818,738 - 2,870,200 (+)NCBI
Sequence:
RefSeq Acc Id: XP_020948753   ⟸   XM_021093094
- UniProtKB: A0A287BKW7 (UniProtKB/TrEMBL),   A0A4X1W612 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000039683   ⟸   ENSSSCT00000061800
Ensembl Acc Id: ENSSSCP00000056718   ⟸   ENSSSCT00000036935
Protein Domains
DAGKc


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000038763 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015015312 UniProtKB/TrEMBL
  ENSSSCG00025041082 UniProtKB/TrEMBL
  ENSSSCG00035042721 UniProtKB/TrEMBL
  ENSSSCG00040011314 UniProtKB/TrEMBL
  ENSSSCG00045019669 UniProtKB/TrEMBL
  ENSSSCG00050039711 UniProtKB/TrEMBL
  ENSSSCG00055021149 UniProtKB/TrEMBL
  ENSSSCG00060015363 UniProtKB/TrEMBL
  ENSSSCG00065063838 UniProtKB/TrEMBL
  ENSSSCG00070029000 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000036935 ENTREZGENE
  ENSSSCT00000036935.3 UniProtKB/TrEMBL
  ENSSSCT00015020314.1 UniProtKB/TrEMBL
  ENSSSCT00015020387.1 UniProtKB/TrEMBL
  ENSSSCT00015020462.1 UniProtKB/TrEMBL
  ENSSSCT00025055681.1 UniProtKB/TrEMBL
  ENSSSCT00025055890.1 UniProtKB/TrEMBL
  ENSSSCT00025056118.1 UniProtKB/TrEMBL
  ENSSSCT00025056351.1 UniProtKB/TrEMBL
  ENSSSCT00035056772.1 UniProtKB/TrEMBL
  ENSSSCT00035056777.1 UniProtKB/TrEMBL
  ENSSSCT00035056784.1 UniProtKB/TrEMBL
  ENSSSCT00035056787.1 UniProtKB/TrEMBL
  ENSSSCT00035056790.1 UniProtKB/TrEMBL
  ENSSSCT00040014800.1 UniProtKB/TrEMBL
  ENSSSCT00040014809.1 UniProtKB/TrEMBL
  ENSSSCT00040014823.1 UniProtKB/TrEMBL
  ENSSSCT00040014862.1 UniProtKB/TrEMBL
  ENSSSCT00040014890.1 UniProtKB/TrEMBL
  ENSSSCT00045033649.1 UniProtKB/TrEMBL
  ENSSSCT00045033849.1 UniProtKB/TrEMBL
  ENSSSCT00050053592.1 UniProtKB/TrEMBL
  ENSSSCT00050053596.1 UniProtKB/TrEMBL
  ENSSSCT00050053602.1 UniProtKB/TrEMBL
  ENSSSCT00055041942.1 UniProtKB/TrEMBL
  ENSSSCT00055042076.1 UniProtKB/TrEMBL
  ENSSSCT00055042249.1 UniProtKB/TrEMBL
  ENSSSCT00060020437.1 UniProtKB/TrEMBL
  ENSSSCT00065087624.1 UniProtKB/TrEMBL
  ENSSSCT00065087627.1 UniProtKB/TrEMBL
  ENSSSCT00065087635.1 UniProtKB/TrEMBL
  ENSSSCT00065087639.1 UniProtKB/TrEMBL
  ENSSSCT00070058183.1 UniProtKB/TrEMBL
  ENSSSCT00070058187.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.200.40 UniProtKB/TrEMBL
  Probable inorganic polyphosphate/atp-NAD kinase, domain 1 UniProtKB/TrEMBL
InterPro ATP-NAD_kinase_N UniProtKB/TrEMBL
  CERK_C UniProtKB/TrEMBL
  Diacylglycerol_kinase_cat_dom UniProtKB/TrEMBL
  Lipid_Phosphate_FormReg UniProtKB/TrEMBL
  NAD/diacylglycerol_kinase_sf UniProtKB/TrEMBL
NCBI Gene CERK ENTREZGENE
PANTHER CERAMIDE KINASE UniProtKB/TrEMBL
  SPHINGOSINE KINASE UniProtKB/TrEMBL
Pfam CERK_C UniProtKB/TrEMBL
  DAGK_cat UniProtKB/TrEMBL
  PH_CERK UniProtKB/TrEMBL
PROSITE DAGK UniProtKB/TrEMBL
SMART DAGKc UniProtKB/TrEMBL
Superfamily-SCOP SSF111331 UniProtKB/TrEMBL
UniProt A0A287BKW7 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1W5P7_PIG UniProtKB/TrEMBL
  A0A4X1W612 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0MS54_PIG UniProtKB/TrEMBL
  A0A8D0MW28_PIG UniProtKB/TrEMBL
  A0A8D0TWY2_PIG UniProtKB/TrEMBL
  A0A8D0ZW30_PIG UniProtKB/TrEMBL
  A0A8D1A0P2_PIG UniProtKB/TrEMBL
  A0A8D1DEB2_PIG UniProtKB/TrEMBL
  A0A8D1DEE1_PIG UniProtKB/TrEMBL
  A0A8D1DEG4_PIG UniProtKB/TrEMBL
  A0A8D1DEP0_PIG UniProtKB/TrEMBL
  A0A8D1DF65_PIG UniProtKB/TrEMBL
  A0A8D1MGH2_PIG UniProtKB/TrEMBL
  A0A8D1MHT2_PIG UniProtKB/TrEMBL
  A0A8D1RHJ6_PIG UniProtKB/TrEMBL
  A0A8D1RHQ5_PIG UniProtKB/TrEMBL
  A0A8D1RIU2_PIG UniProtKB/TrEMBL
  A0A8D1T1Q4_PIG UniProtKB/TrEMBL
  A0A8D1TF25_PIG UniProtKB/TrEMBL
  M3VH84_PIG UniProtKB/TrEMBL
VGNC ID VGNC:86586 ENTREZGENE