LRRC32 (leucine rich repeat containing 32) - Rat Genome Database

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Gene: LRRC32 (leucine rich repeat containing 32) Sus scrofa
Analyze
Symbol: LRRC32
Name: leucine rich repeat containing 32
RGD ID: 14272249
Description: ENCODES a protein that exhibits receptor ligand inhibitor activity (ortholog); INVOLVED IN establishment of protein localization to extracellular region (ortholog); negative regulation of activated T cell proliferation (ortholog); negative regulation of cytokine production (ortholog); ASSOCIATED WITH Cleft Palate, Proliferative Retinopathy, and Developmental Delay (ortholog); Developmental Disabilities (ortholog); genetic disease (ortholog); FOUND IN cell surface (inferred); extracellular matrix (inferred); extracellular space (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: leucine-rich repeat-containing protein 32
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl910,802,236 - 10,815,563 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1910,802,228 - 10,815,892 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2911,913,105 - 11,926,575 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
LRRC32
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl910,802,236 - 10,815,563 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1910,802,228 - 10,815,892 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2911,913,105 - 11,926,575 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LRRC32
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381176,657,524 - 76,670,747 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1176,657,524 - 76,670,747 (-)EnsemblGRCh38hg38GRCh38
GRCh371176,368,568 - 76,381,791 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361176,046,222 - 76,058,543 (-)NCBINCBI36Build 36hg18NCBI36
Build 341176,046,222 - 76,058,543NCBI
Celera1173,676,360 - 73,689,583 (-)NCBICelera
Cytogenetic Map11q13.5NCBI
HuRef1172,666,014 - 72,679,237 (-)NCBIHuRef
CHM1_11176,252,093 - 76,265,313 (-)NCBICHM1_1
T2T-CHM13v2.01176,588,003 - 76,601,225 (-)NCBIT2T-CHM13v2.0
Lrrc32
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39798,138,515 - 98,151,038 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl798,138,490 - 98,151,388 (+)EnsemblGRCm39 Ensembl
GRCm38798,489,305 - 98,501,831 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl798,489,283 - 98,502,181 (+)EnsemblGRCm38mm10GRCm38
MGSCv377105,642,732 - 105,650,341 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36788,242,266 - 88,245,111 (+)NCBIMGSCv36mm8
MGSCv36798,369,414 - 98,375,198 (+)NCBIMGSCv36mm8
Celera798,817,398 - 98,825,017 (+)NCBICelera
Cytogenetic Map7E1NCBI
cM Map753.86NCBI
Lrrc32
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81162,196,995 - 162,209,563 (+)NCBIGRCr8
mRatBN7.21152,785,709 - 152,802,997 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1152,786,511 - 152,798,373 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1160,775,758 - 160,787,610 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01167,955,926 - 167,967,778 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01160,829,451 - 160,841,303 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01163,443,972 - 163,457,426 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1163,445,527 - 163,457,424 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01169,648,351 - 169,661,088 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41155,760,527 - 155,771,294 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11155,838,894 - 155,849,700 (+)NCBI
Celera1150,875,833 - 150,887,643 (+)NCBICelera
Cytogenetic Map1q32NCBI
Lrrc32
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541415,296,563 - 15,309,088 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541415,296,704 - 15,309,088 (+)NCBIChiLan1.0ChiLan1.0
LRRC32
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2977,579,273 - 77,592,573 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11178,624,450 - 78,637,749 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01171,708,222 - 71,721,426 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11175,354,997 - 75,368,187 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1175,354,997 - 75,367,440 (-)Ensemblpanpan1.1panPan2
LRRC32
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12122,051,140 - 22,059,714 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2122,051,920 - 22,057,632 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2121,875,962 - 21,895,388 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02122,249,186 - 22,268,633 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2122,249,292 - 22,261,763 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12122,024,459 - 22,043,872 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02122,243,899 - 22,263,312 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02122,163,062 - 22,182,511 (+)NCBIUU_Cfam_GSD_1.0
Lrrc32
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494763,706,129 - 63,716,750 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364985,305,545 - 5,315,539 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364985,305,680 - 5,315,580 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LRRC32
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1167,866,072 - 67,879,177 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl167,864,609 - 67,879,160 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604357,909,760 - 57,923,072 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lrrc32
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624817497,372 - 510,580 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624817497,415 - 510,061 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in LRRC32
620 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 7 4 5 1 1 2 2 1
Below cutoff 3 3 1 13 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000016222   ⟹   ENSSSCP00000015789
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl910,802,236 - 10,815,563 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000062854   ⟹   ENSSSCP00000039731
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl910,801,946 - 10,817,930 (-)Ensembl
RefSeq Acc Id: XM_003129671   ⟹   XP_003129719
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1910,802,228 - 10,815,892 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013979161   ⟹   XP_013834615
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1910,802,228 - 10,814,678 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013979162   ⟹   XP_013834616
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1910,802,228 - 10,812,352 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013979163   ⟹   XP_013834617
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1910,802,228 - 10,814,487 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021062550   ⟹   XP_020918209
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1910,802,229 - 10,814,801 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_003129719   ⟸   XM_003129671
- UniProtKB: F1SUL2 (UniProtKB/TrEMBL),   A0A8D1ZTY5 (UniProtKB/TrEMBL),   A0A8D0YM26 (UniProtKB/TrEMBL),   A0A8D1RGX2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013834615   ⟸   XM_013979161
- UniProtKB: F1SUL2 (UniProtKB/TrEMBL),   A0A8D1ZTY5 (UniProtKB/TrEMBL),   A0A8D0YM26 (UniProtKB/TrEMBL),   A0A8D1RGX2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013834617   ⟸   XM_013979163
- UniProtKB: F1SUL2 (UniProtKB/TrEMBL),   A0A8D1ZTY5 (UniProtKB/TrEMBL),   A0A8D0YM26 (UniProtKB/TrEMBL),   A0A8D1RGX2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013834616   ⟸   XM_013979162
- UniProtKB: F1SUL2 (UniProtKB/TrEMBL),   A0A8D1ZTY5 (UniProtKB/TrEMBL),   A0A8D0YM26 (UniProtKB/TrEMBL),   A0A8D1RGX2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020918209   ⟸   XM_021062550
- UniProtKB: A0A8D1ZTY5 (UniProtKB/TrEMBL),   F1SUL2 (UniProtKB/TrEMBL),   A0A8D1RGX2 (UniProtKB/TrEMBL),   A0A8D0YM26 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000015789   ⟸   ENSSSCT00000016222
RefSeq Acc Id: ENSSSCP00000039731   ⟸   ENSSSCT00000062854


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000014869 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005008508 UniProtKB/TrEMBL
  ENSSSCG00015058362 UniProtKB/TrEMBL
  ENSSSCG00035011087 UniProtKB/TrEMBL
  ENSSSCG00045019334 UniProtKB/TrEMBL
  ENSSSCG00055023710 UniProtKB/TrEMBL
  ENSSSCG00065065200 UniProtKB/TrEMBL
  ENSSSCG00070017199 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000016222 ENTREZGENE
  ENSSSCT00000016222.5 UniProtKB/TrEMBL
  ENSSSCT00005012927.1 UniProtKB/TrEMBL
  ENSSSCT00005012944.1 UniProtKB/TrEMBL
  ENSSSCT00015077956.1 UniProtKB/TrEMBL
  ENSSSCT00015078073.1 UniProtKB/TrEMBL
  ENSSSCT00035013905.1 UniProtKB/TrEMBL
  ENSSSCT00035013909.1 UniProtKB/TrEMBL
  ENSSSCT00045032907.1 UniProtKB/TrEMBL
  ENSSSCT00055046658.1 UniProtKB/TrEMBL
  ENSSSCT00065089499.1 UniProtKB/TrEMBL
  ENSSSCT00070033909.1 UniProtKB/TrEMBL
  ENSSSCT00070033918.1 UniProtKB/TrEMBL
  ENSSSCT00070033922.1 UniProtKB/TrEMBL
  ENSSSCT00070033925.1 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
KEGG Report ssc:100522452 UniProtKB/TrEMBL
NCBI Gene LRRC32 ENTREZGENE
PANTHER FI03225P UniProtKB/TrEMBL
  LEUCINE RICH REPEAT FAMILY PROTEIN UniProtKB/TrEMBL
  LEUCINE-RICH REPEAT DOMAIN-CONTAINING PROTEIN YDDK UniProtKB/TrEMBL
  LEUCINE-RICH REPEAT-CONTAINING PROTEIN 15-LIKE UniProtKB/TrEMBL
  SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN UniProtKB/TrEMBL
  TRANSFORMING GROWTH FACTOR BETA ACTIVATOR LRRC32 UniProtKB/TrEMBL
Pfam LRR_6 UniProtKB/TrEMBL
  LRR_8 UniProtKB/TrEMBL
PRINTS LEURICHRPT UniProtKB/TrEMBL
PROSITE LRR UniProtKB/TrEMBL
SMART LRR_BAC UniProtKB/TrEMBL
  LRR_RI UniProtKB/TrEMBL
  LRR_TYP UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
UniProt A0A4X1UJ29_PIG UniProtKB/TrEMBL
  A0A4X1UJL5_PIG UniProtKB/TrEMBL
  A0A8D0ICP7_PIG UniProtKB/TrEMBL
  A0A8D0ICQ8_PIG UniProtKB/TrEMBL
  A0A8D0PCT6_PIG UniProtKB/TrEMBL
  A0A8D0YM26 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0YS13_PIG UniProtKB/TrEMBL
  A0A8D1RGX2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1ZTY5 ENTREZGENE, UniProtKB/TrEMBL
  F1SUL2 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:108602 ENTREZGENE