CCDC85B (coiled-coil domain containing 85B)

Gene: CCDC85B (coiled-coil domain containing 85B) Sus scrofa

Analyze

Symbol:

CCDC85B

Name:

coiled-coil domain containing 85B

RGD ID:

14271256

Description:

ENCODES a protein that exhibits delta-catenin binding (inferred); INVOLVED IN negative regulation of cell growth (inferred); negative regulation of DNA-templated transcription (inferred); negative regulation of fat cell differentiation (inferred); ASSOCIATED WITH Aicardi-Goutieres Syndrome 3 (ortholog); autosomal recessive cutis laxa type IB (ortholog); Bardet-Biedl syndrome (ortholog); FOUND IN adherens junction (inferred); centrosome (inferred); nucleus (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

coiled-coil domain-containing protein 85B

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	6,436,794 - 6,437,808 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	6,436,787 - 6,437,828 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	5,540,816 - 5,542,354 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Aicardi-Goutieres Syndrome 3 (ISO)

autosomal recessive cutis laxa type IB (ISO)

Bardet-Biedl syndrome (ISO)

genetic disease (ISO)

glycogen storage disease V (ISO)

intellectual disability (ISO)

Recurrent Infections, with Encephalopathy, Hepatic Dysfunction, and Cardiovascular Malformations (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of cell growth (IEA)

negative regulation of DNA-templated transcription (IBA,IEA)

negative regulation of fat cell differentiation (IEA)

Cellular Component

adherens junction (IEA)

centrosome (IEA)

nucleus (IBA,IEA)

Molecular Function

delta-catenin binding (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

CCDC85B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	6,436,794 - 6,437,808 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	6,436,787 - 6,437,828 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	5,540,816 - 5,542,354 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CCDC85B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	65,890,673 - 65,891,635 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	65,890,673 - 65,891,635 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	65,658,144 - 65,659,106 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	65,414,451 - 65,415,682 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	11	62,981,782 - 62,983,013 (+)	NCBI		Celera
Cytogenetic Map	11	q13.1	NCBI
HuRef	11	61,984,466 - 61,985,697 (+)	NCBI		HuRef
CHM1_1	11	65,542,289 - 65,543,520 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	65,883,735 - 65,884,697 (+)	NCBI		T2T-CHM13v2.0

Ccdc85b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	5,503,191 - 5,507,591 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	5,503,208 - 5,507,922 (-)	Ensembl		GRCm39 Ensembl
GRCm38	19	5,453,163 - 5,457,563 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	5,453,180 - 5,457,894 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	5,453,163 - 5,457,549 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	5,456,539 - 5,457,549 (-)	NCBI		MGSCv36	mm8
Celera	19	5,325,136 - 5,329,522 (-)	NCBI		Celera
Cytogenetic Map	19	A	NCBI
cM Map	19	4.33	NCBI

Ccdc85b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	212,192,979 - 212,193,994 (-)	NCBI		GRCr8
mRatBN7.2	1	202,763,645 - 202,764,660 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	202,763,631 - 202,764,703 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	211,115,951 - 211,116,966 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	218,209,051 - 218,210,066 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	210,900,092 - 210,901,107 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	220,835,647 - 220,837,220 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	1	227,764,980 - 227,766,556 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	208,099,703 - 208,100,997 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	200,299,725 - 200,301,298 (-)	NCBI		Celera
Cytogenetic Map	1	q43	NCBI

Ccdc85b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955422	19,432,602 - 19,433,210 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955422	19,432,368 - 19,433,386 (-)	NCBI	ChiLan1.0	ChiLan1.0

CCDC85B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	67,119,320 - 67,120,171 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	68,161,962 - 68,162,975 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	61,250,913 - 61,251,926 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	64,578,202 - 64,581,942 (+)	NCBI	panpan1.1	PanPan1.1	panPan2

CCDC85B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	51,375,015 - 51,376,044 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	51,375,261 - 51,375,866 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	49,983,525 - 49,984,536 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	52,413,106 - 52,414,117 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	52,413,212 - 52,414,066 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	51,513,175 - 51,514,186 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	51,087,534 - 51,088,545 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	51,876,848 - 51,877,859 (-)	NCBI		UU_Cfam_GSD_1.0

Ccdc85b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	7,207,023 - 7,208,062 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936599	3,649,613 - 3,650,221 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936599	3,649,372 - 3,650,408 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CCDC85B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	8,366,166 - 8,367,670 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	8,366,409 - 8,367,017 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	105,655,347 - 105,656,856 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ccdc85b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624767	20,525,942 - 20,526,550 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624767	20,525,728 - 20,527,337 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in CCDC85B
11 total Variants

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003122520	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK236609	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK392326	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU928325	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSSCT00000014175 ⟹ ENSSSCP00000013789

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	2	6,436,794 - 6,437,808 (-)	Ensembl

RefSeq Acc Id:

XM_003122520 ⟹ XP_003122568

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	2	6,436,787 - 6,437,828 (-)	NCBI

Sequence:

show sequence

TTAACGTCATGTGGCCCCGCCCCGGCGCGCGCCCCGCCGCGTGCCCACCCCCGCTCGACTGCTG
CATCCTACGCTCGCTTAACCACAGACCGTCTGCCGAGCGGGTGCTAGAACCCCGGCGCCGCGGA
GCTCGTCGTGGGGCTCCTGGGCCGCGGCGGCGGGCAGGCGATGCTCCAGAGGCCTGAGCAGCCA
TGGAGGCCGAGACGGGCGGCCTGGAGGAGCTGACGGATGAGGAGATGGCGGCTCTGGGCAAGGA
GGAGCTGGTGCGGCGCCTGCGGCGGGAGGAGGCGGCGCGCCTGGCGGCTCTGGTGCAGCGCGGC
CGCCTCATGCAGGAGGTGAATCGGCAGCTACAGGGTCATCTGGGCGAGATCCGCGAGCTCAAGC
AGCTTAACCGGCGCCTACAAGCTGAGAACCGCGAGCTGCGCGACCTCTGCTGCTTCCTGGACTC
GGAGCGCCAGCGCGGGCGGCGCGCCGCGCGCCAGTGGCAGCTCTTCGGAACCCAAGCATCCCGA
GCCGTGCGCGAGGACCTAGGCGGTTGTTGGCAGAAGCTGGCGGAGCTGGAGGGCCGCCAGGAGG
AGCTGCTGCGGGAGAACCTGGCGCTTAAGGAGCTCTGCCTGGCGCTGGGCGAGGAGTGGGGCCC
CCGCGGCGGCCCCGGCGGCTCGGGGGGCTCAGGCGCTGCGCCAACACCCGAGCTGGCTTTGCCC
CCGTGCGGTCCCCGTGACCTGGGCGATGGAAGCTCCAGTACTGGCAGCGTGGGCAGTCCCGATC
AGTTGCCTCTGGCCTGTTCCCCAGATGATTGAGGGTACAGCTTCCCGCCGACGCCCGCCAGGAT
TGGTCCCCAAGCGCCGGGATTGCAGTGAACTTCGGGACTCGAACGCCGCCCCGGCTGCGCACGA
GGGGCCGCTTGCATGGACTTAGAAAACCCTGACGCTGAGGAGGGCCCCTGGCTCTCGCTGGCGG
GGCAGCAGGGGACTGGAGGCTGGAGCGGAGGGACTTGCTGGAGGCTGGGTGGGGGCTAATAAAC
TGAGAAGGAAGCAGAGCC

hide sequence

Protein Sequences


Protein RefSeqs	XP_003122568	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000013789
	ENSSSCP00000013789.1
	ENSSSCP00035039288.1
	ENSSSCP00045029040.1
	ENSSSCP00050033587.1
	ENSSSCP00055020715.1
	ENSSSCP00070028243.1

RefSeq Acc Id:

XP_003122568 ⟸ XM_003122520

- UniProtKB:

F1RU25 (UniProtKB/TrEMBL), A0A4X1UGE5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEAETGGLEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELK
QLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKLAELEGRQE
ELLRENLALKELCLALGEEWGPRGGPGGSGGSGAAPTPELALPPCGPRDLGDGSSSTGSVGSPD
QLPLACSPDD

hide sequence

RefSeq Acc Id:

ENSSSCP00000013789 ⟸ ENSSSCT00000014175

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000012968	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00035069335	UniProtKB/TrEMBL
	ENSSSCG00045024575	UniProtKB/TrEMBL
	ENSSSCG00050057282	UniProtKB/TrEMBL
	ENSSSCG00055013256	UniProtKB/TrEMBL
	ENSSSCG00070017164	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000014175	ENTREZGENE
	ENSSSCT00000014175.3	UniProtKB/TrEMBL
	ENSSSCT00035093604.1	UniProtKB/TrEMBL
	ENSSSCT00045041838.1	UniProtKB/TrEMBL
	ENSSSCT00050078092.1	UniProtKB/TrEMBL
	ENSSSCT00055026072.1	UniProtKB/TrEMBL
	ENSSSCT00070033827.1	UniProtKB/TrEMBL
InterPro	CCDC85	UniProtKB/TrEMBL
KEGG Report	ssc:100525383	UniProtKB/TrEMBL
NCBI Gene	CCDC85B	ENTREZGENE
PANTHER	COILED-COIL DOMAIN-CONTAINING PROTEIN 85B	UniProtKB/TrEMBL
	PTHR13546	UniProtKB/TrEMBL
Pfam	CCDC85	UniProtKB/TrEMBL
UniProt	A0A4X1UGE5	ENTREZGENE, UniProtKB/TrEMBL
	F1RU25	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:86321	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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