CNOT2 (CCR4-NOT transcription complex subunit 2)

Gene: CNOT2 (CCR4-NOT transcription complex subunit 2) Sus scrofa

Analyze

Symbol:

CNOT2

Name:

CCR4-NOT transcription complex subunit 2

RGD ID:

14270794

Description:

ENCODES a protein that exhibits poly(A)-specific ribonuclease activity (ortholog); INVOLVED IN negative regulation of intracellular estrogen receptor signaling pathway (inferred); negative regulation of transcription by RNA polymerase II (inferred); nuclear-transcribed mRNA poly(A) tail shortening (inferred); PARTICIPATES IN microRNA pathway; ASSOCIATED WITH genetic disease (ortholog); Intellectual Developmental Disorder with Nasal Speech, Dysmorphic Facies, and Variable Skeletal Anomalies (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN CCR4-NOT complex (inferred); CCR4-NOT core complex (inferred); cytoplasm (inferred)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	34,426,394 - 34,549,310 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	34,470,911 - 34,548,968 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	37,132,108 - 37,207,783 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Intellectual Developmental Disorder with Nasal Speech, Dysmorphic Facies, and Variable Skeletal Anomalies (ISO)

Neurodevelopmental Disorders (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of intracellular estrogen receptor signaling pathway (IEA)

negative regulation of transcription by RNA polymerase II (IEA)

nuclear-transcribed mRNA poly(A) tail shortening (IEA)

positive regulation of cytoplasmic mRNA processing body assembly (IEA)

regulation of DNA-templated transcription (IEA)

regulation of stem cell population maintenance (IEA)

trophectodermal cell differentiation (IEA)

Cellular Component

CCR4-NOT complex (IEA)

CCR4-NOT core complex (IEA)

cytoplasm (IEA)

cytosol (IEA)

nucleoplasm (IEA)

P-body (IEA)

plasma membrane (IEA)

Molecular Function

poly(A)-specific ribonuclease activity (IEA,ISO)

protein binding (ISO)

transcription corepressor binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

microRNA pathway (ISO)

References

Additional References at PubMed

PMID:14681463	PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

CNOT2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	34,426,394 - 34,549,310 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	34,470,911 - 34,548,968 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	37,132,108 - 37,207,783 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CNOT2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	70,243,018 - 70,354,993 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	70,243,002 - 70,354,993 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	70,636,798 - 70,748,773 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	68,923,044 - 69,035,040 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	12	68,923,488 - 69,033,960	NCBI
Celera	12	70,300,448 - 70,412,447 (+)	NCBI		Celera
Cytogenetic Map	12	q15	NCBI
HuRef	12	67,686,934 - 67,798,932 (+)	NCBI		HuRef
CHM1_1	12	70,606,077 - 70,718,081 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	70,222,411 - 70,334,463 (+)	NCBI		T2T-CHM13v2.0

Cnot2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	116,321,065 - 116,418,891 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	116,321,066 - 116,417,416 (-)	Ensembl		GRCm39 Ensembl
GRCm38	10	116,485,160 - 116,581,900 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	116,485,161 - 116,581,511 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	115,922,217 - 116,018,567 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	115,889,276 - 115,985,621 (-)	NCBI		MGSCv36	mm8
Celera	10	118,426,741 - 118,523,052 (-)	NCBI		Celera
Cytogenetic Map	10	D2	NCBI
cM Map	10	64.76	NCBI

Cnot2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	54,016,447 - 54,117,511 (-)	NCBI		GRCr8
mRatBN7.2	7	52,130,445 - 52,222,338 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	52,130,441 - 52,223,575 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	54,037,151 - 54,128,665 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	56,240,245 - 56,331,759 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	56,018,227 - 56,109,741 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	59,526,105 - 59,617,307 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	59,527,124 - 59,587,385 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	59,537,579 - 59,628,786 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	55,823,982 - 55,880,812 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	55,844,724 - 55,901,542 (-)	NCBI
Celera	7	48,914,667 - 48,971,519 (-)	NCBI		Celera
Cytogenetic Map	7	q22	NCBI

Cnot2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955405	10,451,414 - 10,547,229 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955405	10,451,414 - 10,547,229 (+)	NCBI	ChiLan1.0	ChiLan1.0

CNOT2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	78,258,520 - 78,370,806 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	78,255,483 - 78,367,205 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	67,753,703 - 67,865,375 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	70,520,722 - 70,633,149 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	70,520,722 - 70,633,149 (+)	Ensembl	panpan1.1		panPan2

CNOT2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	12,057,269 - 12,174,405 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	12,009,762 - 12,172,427 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	11,995,863 - 12,112,451 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	12,188,879 - 12,305,324 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	12,141,268 - 12,305,312 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	12,055,404 - 12,171,985 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	12,302,721 - 12,419,265 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	12,426,002 - 12,542,252 (+)	NCBI		UU_Cfam_GSD_1.0

Cnot2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	46,069,715 - 46,170,762 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936545	7,938,934 - 8,042,117 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936545	7,938,934 - 8,040,409 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CNOT2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	65,823,294 - 65,932,588 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	65,861,353 - 65,934,042 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	179,752,841 - 179,862,945 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cnot2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624750	27,430,575 - 27,529,081 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624750	27,433,671 - 27,529,545 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in CNOT2
1481 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	hemolymphoid system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system
High
Medium	10	2	3	5	2	20	2	3	3
Low		2				3
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001243417	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000033	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK230978	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01088473	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSSCT00000040735 ⟹ ENSSSCP00000047203

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	5	34,426,773 - 34,549,312 (+)	Ensembl

RefSeq Acc Id:

ENSSSCT00000046336 ⟹ ENSSSCP00000033319

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	5	34,426,394 - 34,549,310 (+)	Ensembl

RefSeq Acc Id:

ENSSSCT00000049259 ⟹ ENSSSCP00000043629

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	5	34,426,770 - 34,549,311 (+)	Ensembl

RefSeq Acc Id:

ENSSSCT00000055525 ⟹ ENSSSCP00000048840

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	5	34,498,252 - 34,549,311 (+)	Ensembl

RefSeq Acc Id:

ENSSSCT00000061741 ⟹ ENSSSCP00000050680

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	5	34,426,763 - 34,548,665 (+)	Ensembl

RefSeq Acc Id:

ENSSSCT00000064126 ⟹ ENSSSCP00000053498

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	5	34,426,771 - 34,549,310 (+)	Ensembl

RefSeq Acc Id:

NM_001243417 ⟹ NP_001230346

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	5	34,470,911 - 34,548,968 (+)	NCBI

Sequence:

show sequence

CGGGACAAGAAAATTCATGCGAGGGAGAACTGGTGGGCGGTCCTTCCTGTGACACGACCCTTGA
GTGACAGTTCTATTTGATTGCCTCCAGTACTGTGAGGAAAGGACACGACTCTATGGTGAGGACT
GATGGACATACATTATCTGAGAAAAGAAACTACCAGGTGACAAACAGCATGTTTGGTGCTTCAA
GAAAGAAGTTTGTAGAGGGGGTCGACAGTGACTACCATGACGAAAACATGTACTACAGCCAGTC
TTCTATGTTTCCACATCGGTCAGAAAAAGATATGCTGGCATCACCATCTACATCAGGTCAGCTG
TCTCAGTTTGGGGCAAGTTTATACGGGCAACAAAGTGCACTAGGCCTTCCAATGAGGGGGATGA
GCAACAATACCCCTCAGTTAAATCGCAGCTTATCACAAGGCACTCAGTTACCGAGCCACGTCAC
GCCAACAACAGGGGTACCAACAATGTCACTTCACACGCCTCCATCTCCAAGCAGGGGTATTTTG
CCTATGAATCCTAGGAATATGATGAACCACTCCCAGGTTGGTCAGGGCATTGGAATTCCTAGCA
GGACAAATAGCATGAGCAGTTCAGGGTTAGGTAGCCCCAGCAGAAGCTCGCCAAGCATAATATG
TATGCCAAAGCAGCAGCCTTCTCGACAGCCTTTTACTGTGAACAGTATGTCTGGATTTGGAATG
AACAGGAATCAGGCATTTGGAATGAATAACTCCTTATCAAGTAACATTTTTAATGGAACAGATG
GAAGTGAAAATGTGACAGGATTGGACCTTTCAGATTTTCCAGCATTAGCAGACCGAAACAGAAG
GGAAGGAAGTGGTAACCCAACTCCATTAATAAACCCCTTGGCTGGAAGAGCTCCTTATGTTGGA
ATGGTAACAAAACCAGCAAATGAGCAATCCCAGGACTTCTCAATACATAACGAAGACTTTCCAG
CATTACCTGGTTCCAGTTATAAAGATCCAACATCAAGTAATGATGACAGTAAATCTAATTTGAA
TACATCTGGCAAGACAAGTTCAAGTACAGATGGACCCAAATTCCCTGGAGATAAAAGTTCAACA
ACACAAAATAACAACCAGCAGAAAAAAGGGATCCAGGTGTTACCTGATGGTCGGGTTACTAACA
TTCCTCAAGGTATGGTGACGGACCAATTTGGAATGATTGGCCTGTTAACATTTATCAGAGCAGC
AGAGACAGACCCAGGAATGGTACATCTTGCATTAGGAAGTGACTTAACAACATTAGGCCTCAAT
CTGAACTCTCCTGAAAATCTCTACCCCAAATTTGCATCACCCTGGGCATCTTCACCTTGTCGAC
CTCAAGACATAGACTTCCATGTTCCATCTGAATACTTAACGAACATTCACATTAGGGATAAGCT
GGCGGCAATAAAACTCGGTCGATACGGAGAAGATCTTCTCTTCTATCTCTATTACATGAATGGA
GGAGACGTATTACAACTTTTAGCTGCAGTAGAGCTTTTTAACCGTGATTGGAGATACCACAAAG
AAGAACGAGTATGGATTACCAGGGCACCAGGCATGGAGCCAACAATGAAAACCAATACATATGA
GAGGGGAACATATTACTTCTTTGACTGTCTTAACTGGAGGAAAGTAGCTAAGGAGTTCCATCTG
GAATATGACAAATTAGAAGAACGGCCTCACCTGCCATCCACCTTCAACTACAACCCTGCTCAGC
AAGCCTTCTAAAAAAAAAGACTTCCCTTTTCTTGGGGTATGGCTGTCTCAGCACAATACTCAAC
ATAACTGCAGAACTGATGTGGCTCAGGCACCCTGGTTTTAATTCCTTGAGGATCTGGCAATTGG
CTTACGCAAAGGGTCACCATTTGAGGTCCTGCCTTACTAATTATGTGCTGCCCAACAACTAAAT
TTGTCATTTGTTTTTCTCTAGTTCGAGCAGGGTCTGAATTTTTTCATTTATTTTCTTTTTTTGC
CAGCAAACAGACTTGGGTCTGTAAAAACAAGCAAGTACACTGACAGAAGTTTACCATTTAGTTT
TGAAAATGTAAAAAAGAAAACCCACAAGAGACTCAACAAAATTAGACCACAAAATTTGCATTGT
TCATTGTAGCACTATTGGTAATAAAATAACAAATGTTTGTGCATTTTTATGTGAAGATCCTTCT
CGTATTTCATTTGGAAAGATGAGCAAGGTCTGCTTCCTTCATTTTACTTCCCCTTCTGTTTTTG
AAAGGCAGTTTCGCCAAGCTTAACGCAAGAGTATCTGACTGTTTAGAAGAAAGATATTGCCACA
ACCTCTGGTTGGTTTCCAGGGTTGTGTTATTACTGAGCTTCATCTTTCCAGAATGAGCAAAACA
CTGTCCAGTCTTTGTTACGATTTTGTAATAAATGTGTACATTTTTTTTAAATTTTTGGACATCA
CATGAATAAAGGTATGTATGTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001230346	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000033319.2
	ENSSSCP00000050680.3
	ENSSSCP00000053498
	ENSSSCP00000053498.3
	ENSSSCP00005018229.1
	ENSSSCP00005018262.1
	ENSSSCP00005018289.1
	ENSSSCP00005018377.1
	ENSSSCP00005018391.1
	ENSSSCP00005018397.1
	ENSSSCP00005018405.1
	ENSSSCP00005018428.1
	ENSSSCP00015007923.1
	ENSSSCP00015007941.1
	ENSSSCP00015007966.1
	ENSSSCP00015008009.1
	ENSSSCP00015008036.1
	ENSSSCP00015008069.1
	ENSSSCP00015008096.1
	ENSSSCP00025025700.1
	ENSSSCP00025025806.1
	ENSSSCP00025025903.1
	ENSSSCP00025025982.1
	ENSSSCP00025026133.1
	ENSSSCP00030011286.1
	ENSSSCP00030011298.1
	ENSSSCP00030011306.1
	ENSSSCP00030011310.1
	ENSSSCP00030011325.1
	ENSSSCP00035040592.1
	ENSSSCP00035040612.1
	ENSSSCP00035040621.1
	ENSSSCP00035040651.1
	ENSSSCP00035040689.1
	ENSSSCP00035040703.1
	ENSSSCP00035040709.1
	ENSSSCP00040046045.1
	ENSSSCP00040046106.1
	ENSSSCP00040046160.1
	ENSSSCP00040046234.1
	ENSSSCP00040046303.1
	ENSSSCP00045009699.1
	ENSSSCP00045009869.1
	ENSSSCP00045009913.1
	ENSSSCP00050031710.1
	ENSSSCP00050031715.1
	ENSSSCP00050031717.1
	ENSSSCP00050031721.1
	ENSSSCP00050031730.1
	ENSSSCP00055040798.1
	ENSSSCP00055040855.1
	ENSSSCP00055040908.1
	ENSSSCP00055040965.1
	ENSSSCP00055041039.1
	ENSSSCP00055041094.1
	ENSSSCP00055041173.1
	ENSSSCP00060025258.1
	ENSSSCP00060025261.1
	ENSSSCP00060025262.1
	ENSSSCP00060025267.1
	ENSSSCP00060025270.1
	ENSSSCP00060025272.1
	ENSSSCP00060025274.1
	ENSSSCP00065042059.1
	ENSSSCP00065042078.1
	ENSSSCP00065042087.1
	ENSSSCP00065042093.1
	ENSSSCP00065042097.1
	ENSSSCP00065042106.1
	ENSSSCP00065042113.1
	ENSSSCP00065042125.1
	ENSSSCP00065042127.1
	ENSSSCP00070048020.1
	ENSSSCP00070048022.1
	ENSSSCP00070048024.1
	ENSSSCP00070048033.1
	ENSSSCP00070048038.1
	ENSSSCP00070048043.1
	ENSSSCP00070048051.1

RefSeq Acc Id:

NP_001230346 ⟸ NM_001243417

- UniProtKB:

A0A4X1W0T9 (UniProtKB/TrEMBL), A0A286ZPB3 (UniProtKB/TrEMBL), A0A8D0S5K4 (UniProtKB/TrEMBL), A0A8D0MV36 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MVRTDGHTLSEKRNYQVTNSMFGASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLASPST
SGQLSQFGASLYGQQSALGLPMRGMSNNTPQLNRSLSQGTQLPSHVTPTTGVPTMSLHTPPSPS
RGILPMNPRNMMNHSQVGQGIGIPSRTNSMSSSGLGSPSRSSPSIICMPKQQPSRQPFTVNSMS
GFGMNRNQAFGMNNSLSSNIFNGTDGSENVTGLDLSDFPALADRNRREGSGNPTPLINPLAGRA
PYVGMVTKPANEQSQDFSIHNEDFPALPGSSYKDPTSSNDDSKSNLNTSGKTSSSTDGPKFPGD
KSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGLLTFIRAAETDPGMVHLALGSDLTT
LGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSEYLTNIHIRDKLAAIKLGRYGEDLLFYLY
YMNGGDVLQLLAAVELFNRDWRYHKEERVWITRAPGMEPTMKTNTYERGTYYFFDCLNWRKVAK
EFHLEYDKLEERPHLPSTFNYNPAQQAF

hide sequence

RefSeq Acc Id:

ENSSSCP00000053498 ⟸ ENSSSCT00000064126

RefSeq Acc Id:

ENSSSCP00000047203 ⟸ ENSSSCT00000040735

RefSeq Acc Id:

ENSSSCP00000043629 ⟸ ENSSSCT00000049259

RefSeq Acc Id:

ENSSSCP00000048840 ⟸ ENSSSCT00000055525

RefSeq Acc Id:

ENSSSCP00000050680 ⟸ ENSSSCT00000061741

RefSeq Acc Id:

ENSSSCP00000033319 ⟸ ENSSSCT00000046336

Protein Domains

NOT2/NOT3/NOT5 C-terminal

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000000502	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00005019021	UniProtKB/TrEMBL
	ENSSSCG00015013872	UniProtKB/TrEMBL
	ENSSSCG00025044577	UniProtKB/TrEMBL
	ENSSSCG00030018279	UniProtKB/TrEMBL
	ENSSSCG00035071321	UniProtKB/TrEMBL
	ENSSSCG00040073849	UniProtKB/TrEMBL
	ENSSSCG00045008163	UniProtKB/TrEMBL
	ENSSSCG00050054014	UniProtKB/TrEMBL
	ENSSSCG00055025284	UniProtKB/TrEMBL
	ENSSSCG00060043468	UniProtKB/TrEMBL
	ENSSSCG00065070006	UniProtKB/TrEMBL
	ENSSSCG00070028178	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000046336.3	UniProtKB/TrEMBL
	ENSSSCT00000061741.3	UniProtKB/TrEMBL
	ENSSSCT00000064126	ENTREZGENE
	ENSSSCT00000064126.3	UniProtKB/TrEMBL
	ENSSSCT00005029941.1	UniProtKB/TrEMBL
	ENSSSCT00005029985.1	UniProtKB/TrEMBL
	ENSSSCT00005030023.1	UniProtKB/TrEMBL
	ENSSSCT00005030143.1	UniProtKB/TrEMBL
	ENSSSCT00005030168.1	UniProtKB/TrEMBL
	ENSSSCT00005030175.1	UniProtKB/TrEMBL
	ENSSSCT00005030184.1	UniProtKB/TrEMBL
	ENSSSCT00005030210.1	UniProtKB/TrEMBL
	ENSSSCT00015020237.1	UniProtKB/TrEMBL
	ENSSSCT00015020275.1	UniProtKB/TrEMBL
	ENSSSCT00015020330.1	UniProtKB/TrEMBL
	ENSSSCT00015020418.1	UniProtKB/TrEMBL
	ENSSSCT00015020478.1	UniProtKB/TrEMBL
	ENSSSCT00015020532.1	UniProtKB/TrEMBL
	ENSSSCT00015020600.1	UniProtKB/TrEMBL
	ENSSSCT00025060569.1	UniProtKB/TrEMBL
	ENSSSCT00025060818.1	UniProtKB/TrEMBL
	ENSSSCT00025061012.1	UniProtKB/TrEMBL
	ENSSSCT00025061181.1	UniProtKB/TrEMBL
	ENSSSCT00025061544.1	UniProtKB/TrEMBL
	ENSSSCT00030025260.1	UniProtKB/TrEMBL
	ENSSSCT00030025284.1	UniProtKB/TrEMBL
	ENSSSCT00030025297.1	UniProtKB/TrEMBL
	ENSSSCT00030025309.1	UniProtKB/TrEMBL
	ENSSSCT00030025350.1	UniProtKB/TrEMBL
	ENSSSCT00035096416.1	UniProtKB/TrEMBL
	ENSSSCT00035096447.1	UniProtKB/TrEMBL
	ENSSSCT00035096464.1	UniProtKB/TrEMBL
	ENSSSCT00035096517.1	UniProtKB/TrEMBL
	ENSSSCT00035096580.1	UniProtKB/TrEMBL
	ENSSSCT00035096602.1	UniProtKB/TrEMBL
	ENSSSCT00035096612.1	UniProtKB/TrEMBL
	ENSSSCT00040102029.1	UniProtKB/TrEMBL
	ENSSSCT00040102142.1	UniProtKB/TrEMBL
	ENSSSCT00040102228.1	UniProtKB/TrEMBL
	ENSSSCT00040102365.1	UniProtKB/TrEMBL
	ENSSSCT00040102477.1	UniProtKB/TrEMBL
	ENSSSCT00045014021.1	UniProtKB/TrEMBL
	ENSSSCT00045014258.1	UniProtKB/TrEMBL
	ENSSSCT00045014325.1	UniProtKB/TrEMBL
	ENSSSCT00050073635.1	UniProtKB/TrEMBL
	ENSSSCT00050073646.1	UniProtKB/TrEMBL
	ENSSSCT00050073650.1	UniProtKB/TrEMBL
	ENSSSCT00050073656.1	UniProtKB/TrEMBL
	ENSSSCT00050073669.1	UniProtKB/TrEMBL
	ENSSSCT00055051028.1	UniProtKB/TrEMBL
	ENSSSCT00055051098.1	UniProtKB/TrEMBL
	ENSSSCT00055051161.1	UniProtKB/TrEMBL
	ENSSSCT00055051239.1	UniProtKB/TrEMBL
	ENSSSCT00055051331.1	UniProtKB/TrEMBL
	ENSSSCT00055051413.1	UniProtKB/TrEMBL
	ENSSSCT00055051517.1	UniProtKB/TrEMBL
	ENSSSCT00060058963.1	UniProtKB/TrEMBL
	ENSSSCT00060058971.1	UniProtKB/TrEMBL
	ENSSSCT00060058972.1	UniProtKB/TrEMBL
	ENSSSCT00060058983.1	UniProtKB/TrEMBL
	ENSSSCT00060058992.1	UniProtKB/TrEMBL
	ENSSSCT00060058999.1	UniProtKB/TrEMBL
	ENSSSCT00060059003.1	UniProtKB/TrEMBL
	ENSSSCT00065096113.1	UniProtKB/TrEMBL
	ENSSSCT00065096168.1	UniProtKB/TrEMBL
	ENSSSCT00065096187.1	UniProtKB/TrEMBL
	ENSSSCT00065096201.1	UniProtKB/TrEMBL
	ENSSSCT00065096209.1	UniProtKB/TrEMBL
	ENSSSCT00065096227.1	UniProtKB/TrEMBL
	ENSSSCT00065096240.1	UniProtKB/TrEMBL
	ENSSSCT00065096263.1	UniProtKB/TrEMBL
	ENSSSCT00065096267.1	UniProtKB/TrEMBL
	ENSSSCT00070056524.1	UniProtKB/TrEMBL
	ENSSSCT00070056526.1	UniProtKB/TrEMBL
	ENSSSCT00070056528.1	UniProtKB/TrEMBL
	ENSSSCT00070056538.1	UniProtKB/TrEMBL
	ENSSSCT00070056543.1	UniProtKB/TrEMBL
	ENSSSCT00070056548.1	UniProtKB/TrEMBL
	ENSSSCT00070056556.1	UniProtKB/TrEMBL
Gene3D-CATH	2.30.30.1020	UniProtKB/TrEMBL
InterPro	CCR4-NOT_su2/3/5_N_sf	UniProtKB/TrEMBL
	Not2/3/5	UniProtKB/TrEMBL
	NOT2/3/5_C	UniProtKB/TrEMBL
KEGG Report	ssc:100153354	UniProtKB/TrEMBL
NCBI Gene	CNOT2	ENTREZGENE
PANTHER	CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2	UniProtKB/TrEMBL
	PTHR23326	UniProtKB/TrEMBL
Pfam	NOT2_3_5	UniProtKB/TrEMBL
UniProt	A0A286ZPB3	ENTREZGENE, UniProtKB/TrEMBL
	A0A287B339_PIG	UniProtKB/TrEMBL
	A0A4X1W0T9	ENTREZGENE, UniProtKB/TrEMBL
	A0A4X1W1M0_PIG	UniProtKB/TrEMBL
	A0A4X1W1M6_PIG	UniProtKB/TrEMBL
	A0A4X1W274_PIG	UniProtKB/TrEMBL
	A0A4X1W3B8_PIG	UniProtKB/TrEMBL
	A0A8D0MV16_PIG	UniProtKB/TrEMBL
	A0A8D0MV36	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D0S3C1_PIG	UniProtKB/TrEMBL
	A0A8D0S5K4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D0SBC9_PIG	UniProtKB/TrEMBL
	A0A8D0VVY9_PIG	UniProtKB/TrEMBL
	A0A8D1B6X7_PIG	UniProtKB/TrEMBL
	A0A8D1RZP3_PIG	UniProtKB/TrEMBL
	A0A8D1UBD2_PIG	UniProtKB/TrEMBL
UniProt Secondary	A0A287BAG7	UniProtKB/TrEMBL
VGNC ID	VGNC:86834	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

RGD Manual Annotations