NIPA1 (NIPA magnesium transporter 1) - Rat Genome Database

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Gene: NIPA1 (NIPA magnesium transporter 1) Sus scrofa
Analyze
Symbol: NIPA1
Name: NIPA magnesium transporter 1
RGD ID: 14264844
Description: ENCODES a protein that exhibits magnesium ion transmembrane transporter activity (inferred); INVOLVED IN magnesium ion transmembrane transport (inferred); magnesium ion transport (inferred); ASSOCIATED WITH Angelman syndrome (ortholog); autism spectrum disorder (ortholog); autistic disorder (ortholog); FOUND IN early endosome (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: magnesium transporter NIPA1; non imprinted in Prader-Willi/Angelman syndrome 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1532,208,860 - 32,260,006 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11532,208,857 - 32,260,064 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
early endosome  (ISO)
membrane  (IBA,IEA)
plasma membrane  (ISO)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NIPA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1532,208,860 - 32,260,006 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11532,208,857 - 32,260,064 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
NIPA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381522,786,225 - 22,829,789 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1522,773,063 - 22,829,789 (+)EnsemblGRCh38hg38GRCh38
GRCh371523,043,279 - 23,086,843 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361520,594,720 - 20,637,877 (-)NCBINCBI36Build 36hg18NCBI36
Celera151,293,128 - 1,336,596 (+)NCBICelera
Cytogenetic Map15q11.2NCBI
HuRef151,354,946 - 1,373,627 (-)NCBIHuRef
CHM1_11522,992,596 - 23,036,148 (-)NCBICHM1_1
T2T-CHM13v2.01520,458,058 - 20,501,621 (+)NCBIT2T-CHM13v2.0
Nipa1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39755,628,232 - 55,669,348 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl755,627,315 - 55,669,702 (-)EnsemblGRCm39 Ensembl
GRCm38755,978,484 - 56,019,600 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl755,977,567 - 56,019,954 (-)EnsemblGRCm38mm10GRCm38
MGSCv37763,233,854 - 63,274,943 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36755,846,503 - 55,887,592 (-)NCBIMGSCv36mm8
Celera753,324,994 - 53,365,742 (-)NCBICelera
Cytogenetic Map7B5NCBI
cM Map733.42NCBI
Nipa1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81115,608,221 - 116,010,503 (-)NCBIGRCr8
mRatBN7.21106,834,000 - 106,875,148 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1106,834,000 - 106,874,790 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1112,228,307 - 112,265,916 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01120,700,180 - 120,737,786 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01113,949,137 - 113,986,743 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01114,385,484 - 114,422,741 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1114,386,757 - 114,422,733 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01115,392,570 - 115,410,234 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41107,373,113 - 107,390,777 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11107,452,013 - 107,480,546 (-)NCBI
Celera1101,049,294 - 101,085,273 (-)NCBICelera
Cytogenetic Map1q22NCBI
Nipa1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555331,249,500 - 1,284,588 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555331,244,232 - 1,304,497 (-)NCBIChiLan1.0ChiLan1.0
NIPA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21612,121,583 - 12,164,727 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11515,848,675 - 15,891,427 (+)NCBINHGRI_mPanPan1
PanPan1.11520,612,002 - 20,655,771 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1520,617,547 - 20,655,686 (-)Ensemblpanpan1.1panPan2
NIPA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1332,003,454 - 32,056,802 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl332,003,033 - 32,051,684 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha334,626,242 - 34,679,592 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0332,279,913 - 32,333,487 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl332,279,913 - 32,333,493 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1331,813,483 - 31,866,831 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0332,062,845 - 32,116,213 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0332,173,633 - 32,227,205 (-)NCBIUU_Cfam_GSD_1.0
Nipa1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640120,516,973 - 120,537,137 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647138,364,940 - 38,407,314 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647138,363,521 - 38,403,647 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NIPA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12653,718,832 - 53,746,456 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605436,451,033 - 36,492,084 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nipa1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248962,637,891 - 2,683,078 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248962,638,161 - 2,684,524 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in NIPA1
1161 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 20
Low 10 4 3 5 2 3 2 3 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000040767   ⟹   ENSSSCP00000057174
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1532,208,860 - 32,260,006 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000088895   ⟹   ENSSSCP00000071822
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1532,208,859 - 32,259,875 (-)Ensembl
RefSeq Acc Id: XM_021075606   ⟹   XP_020931265
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11532,208,857 - 32,260,064 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020931265   ⟸   XM_021075606
- UniProtKB: A0A480XWL8 (UniProtKB/TrEMBL),   A0A8D1DPM9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000057174   ⟸   ENSSSCT00000040767
RefSeq Acc Id: ENSSSCP00000071822   ⟸   ENSSSCT00000088895


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000040778 Ensembl, UniProtKB/TrEMBL
  ENSSSCG00015026759 UniProtKB/TrEMBL
  ENSSSCG00025043406 UniProtKB/TrEMBL
  ENSSSCG00030026599 UniProtKB/TrEMBL
  ENSSSCG00035029891 UniProtKB/TrEMBL
  ENSSSCG00040016983 UniProtKB/TrEMBL
  ENSSSCG00045020576 UniProtKB/TrEMBL
  ENSSSCG00050029747 UniProtKB/TrEMBL
  ENSSSCG00055005225 UniProtKB/TrEMBL
  ENSSSCG00060014752 UniProtKB/TrEMBL
  ENSSSCG00065012930 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000040767.3 UniProtKB/TrEMBL
  ENSSSCT00015035496.1 UniProtKB/TrEMBL
  ENSSSCT00025058843.1 UniProtKB/TrEMBL
  ENSSSCT00025058913.1 UniProtKB/TrEMBL
  ENSSSCT00030037147.1 UniProtKB/TrEMBL
  ENSSSCT00030037150.1 UniProtKB/TrEMBL
  ENSSSCT00035039595.1 UniProtKB/TrEMBL
  ENSSSCT00040022855.1 UniProtKB/TrEMBL
  ENSSSCT00040022891.1 UniProtKB/TrEMBL
  ENSSSCT00040022924.1 UniProtKB/TrEMBL
  ENSSSCT00045035068.1 UniProtKB/TrEMBL
  ENSSSCT00050040010.1 UniProtKB/TrEMBL
  ENSSSCT00055010191.1 UniProtKB/TrEMBL
  ENSSSCT00060019560.1 UniProtKB/TrEMBL
  ENSSSCT00065017222.1 UniProtKB/TrEMBL
InterPro Mg_trans_NIPA UniProtKB/TrEMBL
NCBI Gene NIPA1 ENTREZGENE
PANTHER MAGNESIUM TRANSPORTER NIPA1 UniProtKB/TrEMBL
  PTHR12570 UniProtKB/TrEMBL
Pfam Mg_trans_NIPA UniProtKB/TrEMBL
Superfamily-SCOP Multidrug resistance efflux transporter EmrE UniProtKB/TrEMBL
UniProt A0A287BM83_PIG UniProtKB/TrEMBL
  A0A480XWL8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1DN48_PIG UniProtKB/TrEMBL
  A0A8D1DPM9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1T2H0_PIG UniProtKB/TrEMBL
VGNC ID VGNC:95455 ENTREZGENE