TKT (transketolase) - Rat Genome Database

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Gene: TKT (transketolase) Sus scrofa
Analyze
Symbol: TKT
Name: transketolase
RGD ID: 14260667
Description: ENCODES a protein that exhibits carbohydrate binding (ortholog); magnesium ion binding (ortholog); monosaccharide binding (ortholog); INVOLVED IN pentose-phosphate shunt (ortholog); pentose-phosphate shunt, non-oxidative branch (ortholog); regulation of growth (ortholog); PARTICIPATES IN pentose phosphate pathway; pentose phosphate pathway - non-oxidative phase; ribose 5-phosphate isomerase deficiency pathway; ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); carcinoma (ortholog); Experimental Mammary Neoplasms (ortholog); FOUND IN cytosol (ortholog); endoplasmic reticulum membrane (ortholog); intracellular membrane-bounded organelle (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1335,348,915 - 35,377,587 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11335,348,921 - 35,377,518 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21338,418,457 - 38,447,124 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:14681463   PMID:17145712  


Genomics

Comparative Map Data
TKT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1335,348,915 - 35,377,587 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11335,348,921 - 35,377,518 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21338,418,457 - 38,447,124 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TKT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38353,224,712 - 53,256,022 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl353,224,712 - 53,256,052 (-)EnsemblGRCh38hg38GRCh38
GRCh37353,258,728 - 53,290,038 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36353,234,704 - 53,264,998 (-)NCBINCBI36Build 36hg18NCBI36
Build 34353,234,705 - 53,264,998NCBI
Celera353,225,747 - 53,257,192 (-)NCBICelera
Cytogenetic Map3p21.1NCBI
HuRef353,308,475 - 53,339,480 (-)NCBIHuRef
CHM1_1353,210,297 - 53,241,712 (-)NCBICHM1_1
T2T-CHM13v2.0353,257,622 - 53,288,998 (-)NCBIT2T-CHM13v2.0
Tkt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391430,271,088 - 30,296,681 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1430,270,316 - 30,296,677 (+)EnsemblGRCm39 Ensembl
GRCm381430,549,131 - 30,574,724 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1430,548,359 - 30,574,720 (+)EnsemblGRCm38mm10GRCm38
MGSCv371431,362,335 - 31,387,908 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361429,378,158 - 29,403,731 (+)NCBIMGSCv36mm8
Celera1426,805,317 - 26,830,435 (+)NCBICelera
Cytogenetic Map14BNCBI
Tkt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2165,723,764 - 5,748,702 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl165,723,762 - 5,748,698 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx165,735,981 - 5,760,697 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0166,881,435 - 6,906,151 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0165,734,559 - 5,759,275 (+)NCBIRnor_WKY
Rnor_6.0166,609,670 - 6,634,608 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl166,609,668 - 6,634,595 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0166,543,529 - 6,568,467 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4165,908,759 - 5,933,695 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1165,908,756 - 5,933,689 (+)NCBI
Celera169,440,328 - 9,465,209 (-)NCBICelera
Cytogenetic Map16p16NCBI
Tkt
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554303,178,830 - 3,193,345 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554303,178,830 - 3,193,241 (-)NCBIChiLan1.0ChiLan1.0
TKT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1354,389,549 - 54,420,704 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl354,389,549 - 54,420,704 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0353,168,426 - 53,199,003 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
TKT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12036,690,540 - 36,705,980 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2036,681,531 - 36,742,199 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2036,617,359 - 36,642,352 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02036,959,138 - 36,984,142 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2036,958,981 - 36,984,141 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12036,395,903 - 36,420,888 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02036,757,580 - 36,782,577 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02036,972,262 - 36,997,252 (+)NCBIUU_Cfam_GSD_1.0
Tkt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118170,812,273 - 170,840,216 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364733,950,920 - 3,978,672 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049364733,950,846 - 3,978,778 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TKT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12214,620,340 - 14,650,694 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2214,620,287 - 14,650,655 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041152,245,198 - 152,275,549 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tkt
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248223,989,299 - 4,014,269 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248223,989,292 - 4,014,150 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 10 2 3 5 1 23 2 2 3
Low 2 1 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000025213   ⟹   ENSSSCP00000026108
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1335,348,931 - 35,377,587 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000082822   ⟹   ENSSSCP00000066483
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1335,348,933 - 35,367,172 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000089677   ⟹   ENSSSCP00000073402
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1335,348,931 - 35,377,485 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000102365   ⟹   ENSSSCP00000080465
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1335,348,915 - 35,363,067 (-)Ensembl
RefSeq Acc Id: NM_001112681   ⟹   NP_001106151
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11335,348,950 - 35,377,484 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021068188   ⟹   XP_020923847
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11335,348,921 - 35,377,518 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001106151 (Get FASTA)   NCBI Sequence Viewer  
  XP_020923847 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ABW97521 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_020923847   ⟸   XM_021068188
- Peptide Label: isoform X1
- UniProtKB: A0A5G2RF77 (UniProtKB/TrEMBL),   A0A4X1VLN0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001106151   ⟸   NM_001112681
- UniProtKB: A8U4R4 (UniProtKB/TrEMBL),   A0A8D0RHS3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000026108   ⟸   ENSSSCT00000025213
RefSeq Acc Id: ENSSSCP00000073402   ⟸   ENSSSCT00000089677
RefSeq Acc Id: ENSSSCP00000066483   ⟸   ENSSSCT00000082822
RefSeq Acc Id: ENSSSCP00000080465   ⟸   ENSSSCT00000102365
Protein Domains
Transket_pyr   TRANSKETOLASE_1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000021408 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015059418 UniProtKB/TrEMBL
  ENSSSCG00025021846 UniProtKB/TrEMBL
  ENSSSCG00030064387 UniProtKB/TrEMBL
  ENSSSCG00035073588 UniProtKB/TrEMBL
  ENSSSCG00040075402 UniProtKB/TrEMBL
  ENSSSCG00045039543 UniProtKB/TrEMBL
  ENSSSCG00050044411 UniProtKB/TrEMBL
  ENSSSCG00055011818 UniProtKB/TrEMBL
  ENSSSCG00060044381 UniProtKB/TrEMBL
  ENSSSCG00065073649 UniProtKB/TrEMBL
  ENSSSCG00070025283 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000026108 ENTREZGENE
  ENSSSCP00000026108.2 UniProtKB/TrEMBL
  ENSSSCP00000066483.1 UniProtKB/TrEMBL
  ENSSSCP00000073402 ENTREZGENE
  ENSSSCP00000073402.1 UniProtKB/TrEMBL
  ENSSSCP00015032033.1 UniProtKB/TrEMBL
  ENSSSCP00015032206.1 UniProtKB/TrEMBL
  ENSSSCP00015032244.1 UniProtKB/TrEMBL
  ENSSSCP00025012644.1 UniProtKB/TrEMBL
  ENSSSCP00025012661.1 UniProtKB/TrEMBL
  ENSSSCP00025012668.1 UniProtKB/TrEMBL
  ENSSSCP00025012671.1 UniProtKB/TrEMBL
  ENSSSCP00030041525.1 UniProtKB/TrEMBL
  ENSSSCP00030041543.1 UniProtKB/TrEMBL
  ENSSSCP00035042289.1 UniProtKB/TrEMBL
  ENSSSCP00035042303.1 UniProtKB/TrEMBL
  ENSSSCP00035042333.1 UniProtKB/TrEMBL
  ENSSSCP00040047682.1 UniProtKB/TrEMBL
  ENSSSCP00040047689.1 UniProtKB/TrEMBL
  ENSSSCP00040047706.1 UniProtKB/TrEMBL
  ENSSSCP00040047711.1 UniProtKB/TrEMBL
  ENSSSCP00045049130.1 UniProtKB/TrEMBL
  ENSSSCP00045049131.1 UniProtKB/TrEMBL
  ENSSSCP00045049132.1 UniProtKB/TrEMBL
  ENSSSCP00045049133.1 UniProtKB/TrEMBL
  ENSSSCP00045049134.1 UniProtKB/TrEMBL
  ENSSSCP00050026011.1 UniProtKB/TrEMBL
  ENSSSCP00050026015.1 UniProtKB/TrEMBL
  ENSSSCP00050026019.1 UniProtKB/TrEMBL
  ENSSSCP00055018271.1 UniProtKB/TrEMBL
  ENSSSCP00055018337.1 UniProtKB/TrEMBL
  ENSSSCP00055018401.1 UniProtKB/TrEMBL
  ENSSSCP00055018438.1 UniProtKB/TrEMBL
  ENSSSCP00060025807.1 UniProtKB/TrEMBL
  ENSSSCP00060025821.1 UniProtKB/TrEMBL
  ENSSSCP00060025824.1 UniProtKB/TrEMBL
  ENSSSCP00065044659.1 UniProtKB/TrEMBL
  ENSSSCP00065044678.1 UniProtKB/TrEMBL
  ENSSSCP00065044699.1 UniProtKB/TrEMBL
  ENSSSCP00070042727.1 UniProtKB/TrEMBL
  ENSSSCP00070042729.1 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000025213 ENTREZGENE
  ENSSSCT00000025213.3 UniProtKB/TrEMBL
  ENSSSCT00000082822.1 UniProtKB/TrEMBL
  ENSSSCT00000089677 ENTREZGENE
  ENSSSCT00000089677.1 UniProtKB/TrEMBL
  ENSSSCT00015079387.1 UniProtKB/TrEMBL
  ENSSSCT00015079734.1 UniProtKB/TrEMBL
  ENSSSCT00015079827.1 UniProtKB/TrEMBL
  ENSSSCT00025029723.1 UniProtKB/TrEMBL
  ENSSSCT00025029765.1 UniProtKB/TrEMBL
  ENSSSCT00025029779.1 UniProtKB/TrEMBL
  ENSSSCT00025029782.1 UniProtKB/TrEMBL
  ENSSSCT00030090105.1 UniProtKB/TrEMBL
  ENSSSCT00030090156.1 UniProtKB/TrEMBL
  ENSSSCT00035099803.1 UniProtKB/TrEMBL
  ENSSSCT00035099823.1 UniProtKB/TrEMBL
  ENSSSCT00035099871.1 UniProtKB/TrEMBL
  ENSSSCT00040104578.1 UniProtKB/TrEMBL
  ENSSSCT00040104591.1 UniProtKB/TrEMBL
  ENSSSCT00040104614.1 UniProtKB/TrEMBL
  ENSSSCT00040104624.1 UniProtKB/TrEMBL
  ENSSSCT00045068948.1 UniProtKB/TrEMBL
  ENSSSCT00045068949.1 UniProtKB/TrEMBL
  ENSSSCT00045068950.1 UniProtKB/TrEMBL
  ENSSSCT00045068951.1 UniProtKB/TrEMBL
  ENSSSCT00045068952.1 UniProtKB/TrEMBL
  ENSSSCT00050060473.1 UniProtKB/TrEMBL
  ENSSSCT00050060479.1 UniProtKB/TrEMBL
  ENSSSCT00050060487.1 UniProtKB/TrEMBL
  ENSSSCT00055023106.1 UniProtKB/TrEMBL
  ENSSSCT00055023188.1 UniProtKB/TrEMBL
  ENSSSCT00055023274.1 UniProtKB/TrEMBL
  ENSSSCT00055023317.1 UniProtKB/TrEMBL
  ENSSSCT00060060194.1 UniProtKB/TrEMBL
  ENSSSCT00060060231.1 UniProtKB/TrEMBL
  ENSSSCT00060060239.1 UniProtKB/TrEMBL
  ENSSSCT00065101406.1 UniProtKB/TrEMBL
  ENSSSCT00065101444.1 UniProtKB/TrEMBL
  ENSSSCT00065101487.1 UniProtKB/TrEMBL
  ENSSSCT00070050552.1 UniProtKB/TrEMBL
  ENSSSCT00070050555.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.920 UniProtKB/TrEMBL
InterPro THDP-binding UniProtKB/TrEMBL
  Transketo_C/PFOR_II UniProtKB/TrEMBL
  Transketolase-like_Pyr-bd UniProtKB/TrEMBL
  Transketolase_BS UniProtKB/TrEMBL
  Transketolase_C UniProtKB/TrEMBL
  Transketolase_N UniProtKB/TrEMBL
KEGG Report ssc:100127150 UniProtKB/TrEMBL
NCBI Gene TKT ENTREZGENE
Pfam Transket_pyr UniProtKB/TrEMBL
  Transketolase_C UniProtKB/TrEMBL
  Transketolase_N UniProtKB/TrEMBL
PROSITE TRANSKETOLASE_1 UniProtKB/TrEMBL
  TRANSKETOLASE_2 UniProtKB/TrEMBL
SMART Transket_pyr UniProtKB/TrEMBL
Superfamily-SCOP SSF52518 UniProtKB/TrEMBL
  SSF52922 UniProtKB/TrEMBL
UniProt A0A4X1VH46_PIG UniProtKB/TrEMBL
  A0A4X1VLN0 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2QNL3_PIG UniProtKB/TrEMBL
  A0A5G2RF77 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0R988_PIG UniProtKB/TrEMBL
  A0A8D0RHS3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1BAJ7_PIG UniProtKB/TrEMBL
  A0A8D1LAT0_PIG UniProtKB/TrEMBL
  A8U4R4 ENTREZGENE, UniProtKB/TrEMBL
  I3LPT1_PIG UniProtKB/TrEMBL
VGNC ID VGNC:94008 ENTREZGENE