MIR450A (microRNA mir-450a) - Rat Genome Database

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Gene: MIR450A (microRNA mir-450a) Sus scrofa
Analyze
Symbol: MIR450A (Ensembl: ssc-mir-450a)
Name: microRNA mir-450a (Ensembl:ssc-mir-450a)
RGD ID: 14257792
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: microRNA 450a; MIR450; ssc-mir-450; ssc-mir-450a
RGD Orthologs
Human
Mouse
Rat
Dog
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX110,381,746 - 110,381,851 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X110,381,746 - 110,381,851 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
RISC complex  (IEA)

References
Additional References at PubMed
PMID:16381832   PMID:19196471   PMID:19917043   PMID:21312241  


Genomics

Comparative Map Data
MIR450A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX110,381,746 - 110,381,851 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X110,381,746 - 110,381,851 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
MIR450A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X134,540,341 - 134,540,431 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX134,540,341 - 134,540,431 (-)EnsemblGRCh38hg38GRCh38
GRCh37X133,674,371 - 133,674,461 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X133,502,036 - 133,502,126 (-)NCBINCBI36Build 36hg18NCBI36
CeleraX134,061,199 - 134,061,289 (-)NCBICelera
Cytogenetic MapXq26.3NCBI
HuRefX123,073,367 - 123,073,457 (-)NCBIHuRef
CHM1_1X133,586,121 - 133,586,211 (-)NCBICHM1_1
T2T-CHM13v2.0X132,865,540 - 132,865,630 (-)NCBIT2T-CHM13v2.0
Mir450-1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X52,137,031 - 52,137,121 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX52,137,031 - 52,137,121 (-)EnsemblGRCm39 Ensembl
GRCm38X53,048,154 - 53,048,244 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX53,048,154 - 53,048,244 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X50,401,331 - 50,401,421 (-)NCBIGRCm37MGSCv37mm9NCBIm37
CeleraX40,474,149 - 40,474,239 (-)NCBICelera
Cytogenetic MapXA5NCBI
cM MapX29.31NCBI
Mir450a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X137,720,933 - 137,721,023 (-)NCBIGRCr8
mRatBN7.2X132,801,380 - 132,801,470 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX132,801,380 - 132,801,470 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX134,961,429 - 134,961,519 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X138,544,277 - 138,544,367 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X136,109,989 - 136,110,079 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X158,153,377 - 158,153,467 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX158,153,377 - 158,153,467 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X152,778,684 - 152,778,774 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Cytogenetic MapXq36NCBI
MIR450A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X105,177,439 - 105,177,529 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX105,177,439 - 105,177,529 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX91,288,110 - 91,288,200 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X107,037,191 - 107,037,281 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX107,037,191 - 107,037,281 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X104,450,644 - 104,450,734 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X106,316,621 - 106,316,711 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X106,108,087 - 106,108,177 (-)NCBIUU_Cfam_GSD_1.0


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system nervous system
High
Medium 1
Low 8
Below cutoff 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NR_035376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AEMK02000122 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSSCT00000020916
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 EnsemblX110,381,746 - 110,381,851 (-)Ensembl
RefSeq Acc Id: NR_035376
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1X110,381,746 - 110,381,851 (-)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000019321 Ensembl, ENTREZGENE
Ensembl Transcript ENSSSCT00000020916 ENTREZGENE
miRBase MI0010683 ENTREZGENE
NCBI Gene MIR450A ENTREZGENE
RNAcentral URS00003E5ECC RNACentral
  URS000075E36B RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-02 MIR450A  microRNA mir-450a    microRNA 450a  Symbol and/or name change 5135510 APPROVED