SHKBP1 (SH3KBP1 binding protein 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: SHKBP1 (SH3KBP1 binding protein 1) Sus scrofa
Analyze
Symbol: SHKBP1
Name: SH3KBP1 binding protein 1
RGD ID: 14257494
Description: ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN positive regulation of epidermal growth factor receptor signaling pathway (inferred); protein homooligomerization (inferred); ASSOCIATED WITH Carpenter Syndrome 2 (ortholog); congenital hypoplastic anemia (ortholog); craniosynostosis (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: SH3KBP1-binding protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl648,813,168 - 48,826,457 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1648,813,163 - 48,826,461 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
SHKBP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl648,813,168 - 48,826,457 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1648,813,163 - 48,826,461 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SHKBP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381940,576,873 - 40,591,397 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1940,576,853 - 40,591,399 (+)EnsemblGRCh38hg38GRCh38
GRCh371941,082,779 - 41,097,303 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361945,774,630 - 45,789,141 (+)NCBINCBI36Build 36hg18NCBI36
Build 341945,774,629 - 45,789,141NCBI
Celera1937,881,810 - 37,896,356 (+)NCBICelera
Cytogenetic Map19q13.2NCBI
HuRef1937,517,305 - 37,531,390 (+)NCBIHuRef
CHM1_11941,082,689 - 41,097,190 (+)NCBICHM1_1
T2T-CHM13v2.01943,397,488 - 43,411,988 (+)NCBIT2T-CHM13v2.0
Shkbp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39727,041,553 - 27,055,440 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl727,041,558 - 27,055,444 (-)EnsemblGRCm39 Ensembl
GRCm38727,342,128 - 27,356,015 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl727,342,133 - 27,356,019 (-)EnsemblGRCm38mm10GRCm38
MGSCv37728,127,152 - 28,141,027 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36727,050,897 - 27,064,779 (-)NCBIMGSCv36mm8
Celera721,921,926 - 21,935,907 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map715.88NCBI
Shkbp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8191,764,426 - 91,777,959 (-)NCBIGRCr8
mRatBN7.2182,636,797 - 82,650,330 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl182,636,797 - 82,650,375 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx188,039,474 - 88,052,984 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0196,526,308 - 96,539,792 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0189,795,329 - 89,808,840 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0184,154,703 - 84,168,074 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl184,154,703 - 84,168,074 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0185,365,817 - 85,379,188 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4182,422,792 - 82,436,208 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1182,500,913 - 82,514,376 (-)NCBI
Celera177,048,385 - 77,061,819 (-)NCBICelera
Cytogenetic Map1q21NCBI
Shkbp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955578716,632 - 730,593 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955578716,818 - 730,593 (-)NCBIChiLan1.0ChiLan1.0
SHKBP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22046,836,135 - 46,850,721 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11948,707,060 - 48,721,631 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01937,621,867 - 37,636,431 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11946,128,717 - 46,143,423 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1946,128,717 - 46,143,423 (+)Ensemblpanpan1.1panPan2
SHKBP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11113,154,285 - 113,165,988 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1113,154,460 - 113,165,992 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1112,556,527 - 112,568,204 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01113,752,860 - 113,764,552 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1113,752,862 - 113,764,574 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11113,312,464 - 113,324,148 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01112,944,344 - 112,956,029 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01113,938,677 - 113,950,366 (-)NCBIUU_Cfam_GSD_1.0
Shkbp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934914,475,905 - 14,487,839 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366612,903,938 - 2,915,910 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366612,903,986 - 2,915,908 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SHKBP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1635,036,834 - 35,050,953 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607313,160,024 - 13,173,997 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Shkbp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624925529,182 - 542,436 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624925529,333 - 542,230 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SHKBP1
130 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 9 2 1 5 2 15 1 3 3
Below cutoff 1 2 2 8 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000042300   ⟹   ENSSSCP00000043540
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl648,813,168 - 48,826,456 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000050243   ⟹   ENSSSCP00000042652
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl648,813,179 - 48,826,457 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000071298   ⟹   ENSSSCP00000073455
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl648,813,179 - 48,826,455 (+)Ensembl
RefSeq Acc Id: XM_021094397   ⟹   XP_020950056
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1648,813,163 - 48,826,461 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021094398   ⟹   XP_020950057
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1648,813,163 - 48,826,461 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020950056   ⟸   XM_021094397
- Peptide Label: isoform X1
- UniProtKB: A0A8D0Q3A0 (UniProtKB/TrEMBL),   A0A287AI32 (UniProtKB/TrEMBL),   A0A8D0M9R0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020950057   ⟸   XM_021094398
- Peptide Label: isoform X2
- UniProtKB: A0A287AF49 (UniProtKB/TrEMBL),   A0A8D0TSK6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000042652   ⟸   ENSSSCT00000050243
RefSeq Acc Id: ENSSSCP00000043540   ⟸   ENSSSCT00000042300
RefSeq Acc Id: ENSSSCP00000073455   ⟸   ENSSSCT00000071298
Protein Domains
BTB


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000033836 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005045905 UniProtKB/TrEMBL
  ENSSSCG00015076612 UniProtKB/TrEMBL
  ENSSSCG00030071536 UniProtKB/TrEMBL
  ENSSSCG00035002462 UniProtKB/TrEMBL
  ENSSSCG00040025100 UniProtKB/TrEMBL
  ENSSSCG00045026236 UniProtKB/TrEMBL
  ENSSSCG00050012258 UniProtKB/TrEMBL
  ENSSSCG00055011045 UniProtKB/TrEMBL
  ENSSSCG00060004044 UniProtKB/TrEMBL
  ENSSSCG00065064765 UniProtKB/TrEMBL
  ENSSSCG00070002888 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000042300 ENTREZGENE
  ENSSSCT00000042300.3 UniProtKB/TrEMBL
  ENSSSCT00000050243 ENTREZGENE
  ENSSSCT00000050243.3 UniProtKB/TrEMBL
  ENSSSCT00000071298.1 UniProtKB/TrEMBL
  ENSSSCT00005074302.1 UniProtKB/TrEMBL
  ENSSSCT00005074305.1 UniProtKB/TrEMBL
  ENSSSCT00015103340.1 UniProtKB/TrEMBL
  ENSSSCT00015103424.1 UniProtKB/TrEMBL
  ENSSSCT00015103509.1 UniProtKB/TrEMBL
  ENSSSCT00030100146.1 UniProtKB/TrEMBL
  ENSSSCT00030100179.1 UniProtKB/TrEMBL
  ENSSSCT00030100215.1 UniProtKB/TrEMBL
  ENSSSCT00035003083.1 UniProtKB/TrEMBL
  ENSSSCT00035003090.1 UniProtKB/TrEMBL
  ENSSSCT00035003092.1 UniProtKB/TrEMBL
  ENSSSCT00035003094.1 UniProtKB/TrEMBL
  ENSSSCT00040033482.1 UniProtKB/TrEMBL
  ENSSSCT00040033605.1 UniProtKB/TrEMBL
  ENSSSCT00040033740.1 UniProtKB/TrEMBL
  ENSSSCT00045044627.1 UniProtKB/TrEMBL
  ENSSSCT00045044875.1 UniProtKB/TrEMBL
  ENSSSCT00045045057.1 UniProtKB/TrEMBL
  ENSSSCT00045045231.1 UniProtKB/TrEMBL
  ENSSSCT00050016528.1 UniProtKB/TrEMBL
  ENSSSCT00050016537.1 UniProtKB/TrEMBL
  ENSSSCT00050016552.1 UniProtKB/TrEMBL
  ENSSSCT00055021660.1 UniProtKB/TrEMBL
  ENSSSCT00055021751.1 UniProtKB/TrEMBL
  ENSSSCT00055021814.1 UniProtKB/TrEMBL
  ENSSSCT00060005001.1 UniProtKB/TrEMBL
  ENSSSCT00060005072.1 UniProtKB/TrEMBL
  ENSSSCT00060005076.1 UniProtKB/TrEMBL
  ENSSSCT00065088891.1 UniProtKB/TrEMBL
  ENSSSCT00065088899.1 UniProtKB/TrEMBL
  ENSSSCT00065088907.1 UniProtKB/TrEMBL
  ENSSSCT00070005410.1 UniProtKB/TrEMBL
  ENSSSCT00070005436.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro BTB/POZ_dom UniProtKB/TrEMBL
  SHKBP1/KCTD3 UniProtKB/TrEMBL
  SHKBP1_KCTD3_BTB_POZ UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/TrEMBL
  T1-type_BTB UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
NCBI Gene SHKBP1 ENTREZGENE
PANTHER SETA BINDING PROTEIN 1 UniProtKB/TrEMBL
  SH3KBP1-BINDING PROTEIN 1 UniProtKB/TrEMBL
Pfam BTB_2 UniProtKB/TrEMBL
PROSITE BTB UniProtKB/TrEMBL
SMART BTB UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
  SSF54695 UniProtKB/TrEMBL
UniProt A0A287AF49 ENTREZGENE, UniProtKB/TrEMBL
  A0A287AI32 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1SPA7_PIG UniProtKB/TrEMBL
  A0A4X1SQR0_PIG UniProtKB/TrEMBL
  A0A5G2RAU6_PIG UniProtKB/TrEMBL
  A0A8D0M9R0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0Q3A0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0Q9Z2_PIG UniProtKB/TrEMBL
  A0A8D0TSK6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0YGS8_PIG UniProtKB/TrEMBL
  A0A8D1CJS5_PIG UniProtKB/TrEMBL
VGNC ID VGNC:92853 ENTREZGENE