MITD1 (microtubule interacting and trafficking domain containing 1) - Rat Genome Database

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Gene: MITD1 (microtubule interacting and trafficking domain containing 1) Sus scrofa
Analyze
Symbol: MITD1
Name: microtubule interacting and trafficking domain containing 1
RGD ID: 14256006
Description: ENCODES a protein that exhibits identical protein binding (inferred); phosphatidylinositol binding (inferred); protein domain specific binding (inferred); INVOLVED IN multivesicular body sorting pathway (ortholog); viral budding via host ESCRT complex (ortholog); ASSOCIATED WITH Cardiovascular Abnormalities (ortholog); Failure to Thrive (ortholog); genetic disease (ortholog); FOUND IN intracellular membrane-bounded organelle (inferred); membrane (inferred); midbody (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: MIT domain-containing protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl355,054,517 - 55,069,866 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1355,054,475 - 55,078,180 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2357,688,426 - 57,703,819 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:15679890   PMID:30032202  


Genomics

Comparative Map Data
MITD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl355,054,517 - 55,069,866 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1355,054,475 - 55,078,180 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2357,688,426 - 57,703,819 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MITD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38299,161,427 - 99,181,058 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl299,161,427 - 99,181,058 (-)EnsemblGRCh38hg38GRCh38
GRCh37299,785,726 - 99,797,521 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36299,152,158 - 99,163,924 (-)NCBINCBI36Build 36hg18NCBI36
Celera293,990,319 - 94,002,087 (-)NCBICelera
Cytogenetic Map2q11.2NCBI
HuRef293,551,497 - 93,563,265 (-)NCBIHuRef
CHM1_1299,790,624 - 99,802,390 (-)NCBICHM1_1
T2T-CHM13v2.0299,620,306 - 99,639,936 (-)NCBIT2T-CHM13v2.0
Mitd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39137,913,882 - 37,929,530 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl137,913,882 - 37,929,492 (-)EnsemblGRCm39 Ensembl
GRCm38137,874,801 - 37,890,449 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl137,874,801 - 37,890,411 (-)EnsemblGRCm38mm10GRCm38
MGSCv37137,935,735 - 37,947,256 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36137,823,275 - 37,834,979 (-)NCBIMGSCv36mm8
Celera137,659,809 - 37,671,331 (-)NCBICelera
Cytogenetic Map1BNCBI
cM Map116.13NCBI
Mitd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8947,609,743 - 47,621,033 (-)NCBIGRCr8
mRatBN7.2940,113,943 - 40,125,280 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl940,113,946 - 40,125,289 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx948,609,792 - 48,621,053 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0953,732,547 - 53,743,808 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0952,014,641 - 52,025,935 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0944,472,364 - 44,483,723 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl944,472,365 - 44,560,837 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0944,169,744 - 44,181,102 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4936,827,857 - 36,839,148 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1936,829,271 - 36,840,562 (-)NCBI
Celera937,868,172 - 37,879,466 (-)NCBICelera
Cytogenetic Map9q21NCBI
Mitd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554705,493,144 - 5,509,437 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554705,493,361 - 5,509,437 (-)NCBIChiLan1.0ChiLan1.0
MITD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21229,248,958 - 29,263,284 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A29,251,722 - 29,266,044 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A100,116,263 - 100,130,580 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A100,097,758 - 100,111,589 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A100,097,758 - 100,111,589 (-)Ensemblpanpan1.1panPan2
MITD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11043,513,240 - 43,525,543 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1043,513,277 - 43,523,883 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1043,436,787 - 43,456,434 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01044,385,417 - 44,405,067 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1044,385,431 - 44,398,060 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11044,095,468 - 44,115,110 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01044,378,979 - 44,391,206 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01044,563,444 - 44,583,084 (+)NCBIUU_Cfam_GSD_1.0
Mitd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629284,937,949 - 84,949,823 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366611,618,975 - 1,633,278 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366611,619,703 - 1,632,558 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MITD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1142,894,096 - 2,902,790 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666041170,496,653 - 170,506,461 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mitd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247494,172,007 - 4,185,890 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247494,166,358 - 4,185,980 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MITD1
1020 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 6 2 3 5 1 18 3 3
Low 4 2 1 5 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000008964   ⟹   ENSSSCP00000008738
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl355,054,517 - 55,069,866 (+)Ensembl
RefSeq Acc Id: XM_003124905   ⟹   XP_003124953
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1355,054,477 - 55,070,558 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021087196   ⟹   XP_020942855
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1355,054,475 - 55,070,558 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002342525
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1355,065,173 - 55,078,180 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020942855   ⟸   XM_021087196
- Peptide Label: isoform X2
- UniProtKB: A0A8D0TZN6 (UniProtKB/TrEMBL),   A0A8D1HVE9 (UniProtKB/TrEMBL),   A0A8D1WGI0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003124953   ⟸   XM_003124905
- Peptide Label: isoform X1
- UniProtKB: F1STE3 (UniProtKB/TrEMBL),   A0A4X1VX69 (UniProtKB/TrEMBL),   A0A8D0TZN6 (UniProtKB/TrEMBL),   A0A8D1HVE9 (UniProtKB/TrEMBL),   A0A8D1WGI0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000008738   ⟸   ENSSSCT00000008964
Protein Domains
MIT


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000008185 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005001206 UniProtKB/TrEMBL
  ENSSSCG00015026220 UniProtKB/TrEMBL
  ENSSSCG00030010877 UniProtKB/TrEMBL
  ENSSSCG00035049431 UniProtKB/TrEMBL
  ENSSSCG00045020856 UniProtKB/TrEMBL
  ENSSSCG00050040603 UniProtKB/TrEMBL
  ENSSSCG00055023723 UniProtKB/TrEMBL
  ENSSSCG00060066616 UniProtKB/TrEMBL
  ENSSSCG00065061522 UniProtKB/TrEMBL
  ENSSSCG00070028401 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000008964 ENTREZGENE
  ENSSSCT00000008964.5 UniProtKB/TrEMBL
  ENSSSCT00005001679.1 UniProtKB/TrEMBL
  ENSSSCT00015034747.1 UniProtKB/TrEMBL
  ENSSSCT00015034771.1 UniProtKB/TrEMBL
  ENSSSCT00015034859.1 UniProtKB/TrEMBL
  ENSSSCT00030014924.1 UniProtKB/TrEMBL
  ENSSSCT00035065899.1 UniProtKB/TrEMBL
  ENSSSCT00045035575.1 UniProtKB/TrEMBL
  ENSSSCT00050054958.1 UniProtKB/TrEMBL
  ENSSSCT00055046686.1 UniProtKB/TrEMBL
  ENSSSCT00060090925.1 UniProtKB/TrEMBL
  ENSSSCT00065084314.1 UniProtKB/TrEMBL
  ENSSSCT00070056945.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.870.30 UniProtKB/TrEMBL
  Phosphotransferase system, lactose/cellobiose-type IIA subunit UniProtKB/TrEMBL
InterPro MIT UniProtKB/TrEMBL
  MIT_C UniProtKB/TrEMBL
  MIT_C_sf UniProtKB/TrEMBL
  MIT_dom_sf UniProtKB/TrEMBL
  MITD1_N UniProtKB/TrEMBL
KEGG Report ssc:100523366 UniProtKB/TrEMBL
NCBI Gene MITD1 ENTREZGENE
PANTHER MIT DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/TrEMBL
Pfam MIT UniProtKB/TrEMBL
  MIT_C UniProtKB/TrEMBL
SMART MIT UniProtKB/TrEMBL
Superfamily-SCOP SSF116846 UniProtKB/TrEMBL
UniProt A0A4X1VX69 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0TZN6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1HVE9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1WGI0 ENTREZGENE, UniProtKB/TrEMBL
  F1STE3 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:90242 ENTREZGENE