SERPINF2 (serpin family F member 2) - Rat Genome Database

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Gene: SERPINF2 (serpin family F member 2) Sus scrofa
Analyze
Symbol: SERPINF2
Name: serpin family F member 2
RGD ID: 14255756
Description: ENCODES a protein that exhibits serine-type endopeptidase inhibitor activity (ortholog); INVOLVED IN negative regulation of fibrinolysis (ortholog); PARTICIPATES IN fibrinolysis pathway; ASSOCIATED WITH acute necrotizing pancreatitis (ortholog); alpha-2-plasmin inhibitor deficiency (ortholog); coronary artery disease (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: alpha-2-antiplasmin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1247,933,864 - 47,942,285 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11247,934,551 - 47,942,283 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SERPINF2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1247,933,864 - 47,942,285 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11247,934,551 - 47,942,283 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SERPINF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38171,742,871 - 1,755,265 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl171,742,836 - 1,755,265 (+)EnsemblGRCh38hg38GRCh38
GRCh37171,646,165 - 1,658,559 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36171,592,880 - 1,605,309 (+)NCBINCBI36Build 36hg18NCBI36
Build 34171,595,035 - 1,605,309NCBI
Celera171,661,914 - 1,674,664 (+)NCBICelera
Cytogenetic Map17p13.3NCBI
HuRef171,543,280 - 1,555,830 (+)NCBIHuRef
CHM1_1171,654,916 - 1,666,631 (+)NCBICHM1_1
T2T-CHM13v2.0171,632,294 - 1,643,959 (+)NCBIT2T-CHM13v2.0
Serpinf2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391175,322,562 - 75,330,327 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1175,322,558 - 75,330,417 (-)EnsemblGRCm39 Ensembl
GRCm381175,431,736 - 75,439,501 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1175,431,732 - 75,439,591 (-)EnsemblGRCm38mm10GRCm38
MGSCv371175,245,238 - 75,253,003 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361175,247,931 - 75,255,676 (-)NCBIMGSCv36mm8
Celera1182,940,136 - 82,947,901 (-)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1145.89NCBI
Serpinf2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81060,770,698 - 60,778,782 (-)NCBIGRCr8
mRatBN7.21060,272,400 - 60,280,506 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1060,272,400 - 60,281,243 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1064,919,282 - 64,927,358 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01064,424,887 - 64,432,963 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01059,887,278 - 59,895,354 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01062,264,247 - 62,272,353 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1062,264,788 - 62,273,119 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01061,978,965 - 61,987,194 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41062,748,116 - 62,756,200 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11062,761,738 - 62,769,823 (-)NCBI
Celera1059,300,854 - 59,308,938 (-)NCBICelera
Cytogenetic Map10q24NCBI
Serpinf2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554811,442,010 - 1,449,242 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554811,441,262 - 1,449,078 (-)NCBIChiLan1.0ChiLan1.0
SERPINF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2199,313,280 - 9,326,540 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11711,279,789 - 11,293,061 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0171,725,469 - 1,738,887 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1171,618,426 - 1,631,571 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl171,618,549 - 1,631,570 (+)Ensemblpanpan1.1panPan2
SERPINF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1945,876,076 - 45,883,777 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl945,877,495 - 45,883,036 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha945,026,864 - 45,034,458 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0946,703,271 - 46,710,872 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl946,703,323 - 46,710,871 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1945,474,549 - 45,480,834 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0945,767,599 - 45,775,185 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0945,822,215 - 45,829,811 (+)NCBIUU_Cfam_GSD_1.0
Serpinf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560244,990,512 - 45,000,032 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365387,870,898 - 7,877,219 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365387,870,898 - 7,877,279 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SERPINF2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1161,392,562 - 1,404,574 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl161,392,571 - 1,404,636 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605920,571,859 - 20,583,948 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Serpinf2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247864,443,249 - 4,449,743 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247864,441,912 - 4,450,487 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SERPINF2
115 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 4 17 3 2 5 14 12 17 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000051082   ⟹   ENSSSCP00000044176
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1247,933,864 - 47,942,280 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000062549   ⟹   ENSSSCP00000053075
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1247,934,109 - 47,942,285 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000071722   ⟹   ENSSSCP00000070332
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1247,933,864 - 47,942,280 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000074671   ⟹   ENSSSCP00000067762
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1247,935,584 - 47,942,285 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000078844   ⟹   ENSSSCP00000066287
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1247,934,459 - 47,942,285 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000091596   ⟹   ENSSSCP00000069749
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1247,934,617 - 47,942,285 (+)Ensembl
RefSeq Acc Id: XM_021067579   ⟹   XP_020923238
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11247,934,551 - 47,942,283 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020923238 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000044176
  ENSSSCP00000044176.2
  ENSSSCP00000053075.1
  ENSSSCP00000066287.1
  ENSSSCP00000067762.2
  ENSSSCP00000069749.1
  ENSSSCP00000070332.1
  ENSSSCP00015034808.1
  ENSSSCP00015034857.1
  ENSSSCP00025045469.1
  ENSSSCP00025045509.1
  ENSSSCP00025045591.1
  ENSSSCP00025045643.1
  ENSSSCP00025045678.1
  ENSSSCP00030039063.1
  ENSSSCP00030039074.1
  ENSSSCP00030039119.1
  ENSSSCP00030039140.1
  ENSSSCP00035032040.1
  ENSSSCP00035032041.1
  ENSSSCP00035032043.1
  ENSSSCP00035032044.1
  ENSSSCP00035032052.1
  ENSSSCP00035032056.1
  ENSSSCP00040007377.1
  ENSSSCP00040007386.1
  ENSSSCP00040007394.1
  ENSSSCP00040007407.1
  ENSSSCP00040007475.1
  ENSSSCP00040007485.1
  ENSSSCP00045027527.1
  ENSSSCP00045027596.1
  ENSSSCP00045027646.1
  ENSSSCP00045027705.1
  ENSSSCP00045027790.1
  ENSSSCP00045027855.1
  ENSSSCP00050007342.1
  ENSSSCP00050007353.1
  ENSSSCP00050007354.1
  ENSSSCP00055035922.1
  ENSSSCP00055036022.1
  ENSSSCP00055036093.1
  ENSSSCP00055036184.1
  ENSSSCP00055036327.1
  ENSSSCP00055036422.1
  ENSSSCP00060015684.1
  ENSSSCP00060015692.1
  ENSSSCP00060015697.1
  ENSSSCP00060015699.1
  ENSSSCP00065033864.1
  ENSSSCP00065033866.1
  ENSSSCP00065033867.1
  ENSSSCP00070024404.1
  ENSSSCP00070024409.1
  ENSSSCP00070024412.1
  ENSSSCP00070024416.1
  ENSSSCP00070024426.1
  ENSSSCP00070024430.1
  ENSSSCP00070024434.1
  ENSSSCP00070024442.1
RefSeq Acc Id: XP_020923238   ⟸   XM_021067579
- UniProtKB: A0A4X1U954 (UniProtKB/TrEMBL),   A0A287AJI4 (UniProtKB/TrEMBL),   A0A8D1DI61 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000066287   ⟸   ENSSSCT00000078844
Ensembl Acc Id: ENSSSCP00000067762   ⟸   ENSSSCT00000074671
Ensembl Acc Id: ENSSSCP00000044176   ⟸   ENSSSCT00000051082
Ensembl Acc Id: ENSSSCP00000069749   ⟸   ENSSSCT00000091596
Ensembl Acc Id: ENSSSCP00000053075   ⟸   ENSSSCT00000062549
Ensembl Acc Id: ENSSSCP00000070332   ⟸   ENSSSCT00000071722
Protein Domains
SERPIN


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000038745 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015064018 UniProtKB/TrEMBL
  ENSSSCG00025074476 UniProtKB/TrEMBL
  ENSSSCG00030060674 UniProtKB/TrEMBL
  ENSSSCG00035058466 UniProtKB/TrEMBL
  ENSSSCG00040013416 UniProtKB/TrEMBL
  ENSSSCG00045023072 UniProtKB/TrEMBL
  ENSSSCG00050013141 UniProtKB/TrEMBL
  ENSSSCG00055022858 UniProtKB/TrEMBL
  ENSSSCG00060027192 UniProtKB/TrEMBL
  ENSSSCG00065056881 UniProtKB/TrEMBL
  ENSSSCG00070014901 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000051082 ENTREZGENE
  ENSSSCT00000051082.2 UniProtKB/TrEMBL
  ENSSSCT00000062549.3 UniProtKB/TrEMBL
  ENSSSCT00000071722.1 UniProtKB/TrEMBL
  ENSSSCT00000074671.2 UniProtKB/TrEMBL
  ENSSSCT00000078844.2 UniProtKB/TrEMBL
  ENSSSCT00000091596.2 UniProtKB/TrEMBL
  ENSSSCT00015085647.1 UniProtKB/TrEMBL
  ENSSSCT00015085745.1 UniProtKB/TrEMBL
  ENSSSCT00025102687.1 UniProtKB/TrEMBL
  ENSSSCT00025102763.1 UniProtKB/TrEMBL
  ENSSSCT00025102948.1 UniProtKB/TrEMBL
  ENSSSCT00025103042.1 UniProtKB/TrEMBL
  ENSSSCT00025103109.1 UniProtKB/TrEMBL
  ENSSSCT00030084835.1 UniProtKB/TrEMBL
  ENSSSCT00030084855.1 UniProtKB/TrEMBL
  ENSSSCT00030084938.1 UniProtKB/TrEMBL
  ENSSSCT00030084973.1 UniProtKB/TrEMBL
  ENSSSCT00035078249.1 UniProtKB/TrEMBL
  ENSSSCT00035078250.1 UniProtKB/TrEMBL
  ENSSSCT00035078253.1 UniProtKB/TrEMBL
  ENSSSCT00035078254.1 UniProtKB/TrEMBL
  ENSSSCT00035078268.1 UniProtKB/TrEMBL
  ENSSSCT00035078273.1 UniProtKB/TrEMBL
  ENSSSCT00040018003.1 UniProtKB/TrEMBL
  ENSSSCT00040018028.1 UniProtKB/TrEMBL
  ENSSSCT00040018046.1 UniProtKB/TrEMBL
  ENSSSCT00040018070.1 UniProtKB/TrEMBL
  ENSSSCT00040018218.1 UniProtKB/TrEMBL
  ENSSSCT00040018244.1 UniProtKB/TrEMBL
  ENSSSCT00045039541.1 UniProtKB/TrEMBL
  ENSSSCT00045039644.1 UniProtKB/TrEMBL
  ENSSSCT00045039712.1 UniProtKB/TrEMBL
  ENSSSCT00045039794.1 UniProtKB/TrEMBL
  ENSSSCT00045039906.1 UniProtKB/TrEMBL
  ENSSSCT00045039985.1 UniProtKB/TrEMBL
  ENSSSCT00050017778.1 UniProtKB/TrEMBL
  ENSSSCT00050017805.1 UniProtKB/TrEMBL
  ENSSSCT00050017807.1 UniProtKB/TrEMBL
  ENSSSCT00055045087.1 UniProtKB/TrEMBL
  ENSSSCT00055045207.1 UniProtKB/TrEMBL
  ENSSSCT00055045292.1 UniProtKB/TrEMBL
  ENSSSCT00055045399.1 UniProtKB/TrEMBL
  ENSSSCT00055045570.1 UniProtKB/TrEMBL
  ENSSSCT00055045677.1 UniProtKB/TrEMBL
  ENSSSCT00060036844.1 UniProtKB/TrEMBL
  ENSSSCT00060036859.1 UniProtKB/TrEMBL
  ENSSSCT00060036870.1 UniProtKB/TrEMBL
  ENSSSCT00060036876.1 UniProtKB/TrEMBL
  ENSSSCT00065077873.1 UniProtKB/TrEMBL
  ENSSSCT00065077884.1 UniProtKB/TrEMBL
  ENSSSCT00065077891.1 UniProtKB/TrEMBL
  ENSSSCT00070029284.1 UniProtKB/TrEMBL
  ENSSSCT00070029290.1 UniProtKB/TrEMBL
  ENSSSCT00070029293.1 UniProtKB/TrEMBL
  ENSSSCT00070029298.1 UniProtKB/TrEMBL
  ENSSSCT00070029308.1 UniProtKB/TrEMBL
  ENSSSCT00070029314.1 UniProtKB/TrEMBL
  ENSSSCT00070029319.1 UniProtKB/TrEMBL
  ENSSSCT00070029330.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.39.10 UniProtKB/TrEMBL
  3.30.497.10 UniProtKB/TrEMBL
InterPro Alpha2AP UniProtKB/TrEMBL
  Serpin_CS UniProtKB/TrEMBL
  Serpin_dom UniProtKB/TrEMBL
  Serpin_fam UniProtKB/TrEMBL
  Serpin_sf UniProtKB/TrEMBL
  Serpin_sf_1 UniProtKB/TrEMBL
  Serpin_sf_2 UniProtKB/TrEMBL
NCBI Gene SERPINF2 ENTREZGENE
PANTHER ALPHA-2-ANTIPLASMIN UniProtKB/TrEMBL
  PTHR11461 UniProtKB/TrEMBL
Pfam Serpin UniProtKB/TrEMBL
PROSITE SERPIN UniProtKB/TrEMBL
SMART SERPIN UniProtKB/TrEMBL
Superfamily-SCOP SSF56574 UniProtKB/TrEMBL
UniProt A0A287AJI4 ENTREZGENE, UniProtKB/TrEMBL
  A0A287B9B3_PIG UniProtKB/TrEMBL
  A0A4X1U3Z8_PIG UniProtKB/TrEMBL
  A0A4X1U429_PIG UniProtKB/TrEMBL
  A0A4X1U6C5_PIG UniProtKB/TrEMBL
  A0A4X1U6D9_PIG UniProtKB/TrEMBL
  A0A4X1U6E7_PIG UniProtKB/TrEMBL
  A0A4X1U6G0_PIG UniProtKB/TrEMBL
  A0A4X1U8G5_PIG UniProtKB/TrEMBL
  A0A4X1U954 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2QN21_PIG UniProtKB/TrEMBL
  A0A5G2QSG7_PIG UniProtKB/TrEMBL
  A0A5G2R885_PIG UniProtKB/TrEMBL
  A0A5G2RFF8_PIG UniProtKB/TrEMBL
  A0A8D0TE68_PIG UniProtKB/TrEMBL
  A0A8D0XSK0_PIG UniProtKB/TrEMBL
  A0A8D0XT67_PIG UniProtKB/TrEMBL
  A0A8D1DI61 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1DIK2_PIG UniProtKB/TrEMBL
  A0A8D1DIU0_PIG UniProtKB/TrEMBL
  A0A8D1K305_PIG UniProtKB/TrEMBL
  A0A8D1RI99_PIG UniProtKB/TrEMBL
  A0A8D1RNI8_PIG UniProtKB/TrEMBL
  A0A8D1UXP7_PIG UniProtKB/TrEMBL
VGNC ID VGNC:92744 ENTREZGENE