DEFB128 (defensin beta 128) - Rat Genome Database

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Gene: DEFB128 (defensin beta 128) Sus scrofa
Analyze
Symbol: DEFB128
Name: defensin beta 128
RGD ID: 14250469
Description: INVOLVED IN defense response to bacterium (inferred); defense response to Gram-negative bacterium (inferred); defense response to Gram-positive bacterium (inferred); ASSOCIATED WITH genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN extracellular region (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: beta-defensin 128
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1734,963,374 - 34,966,317 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11734,948,185 - 34,965,455 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21739,738,270 - 39,740,120 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
DEFB128
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1734,963,374 - 34,966,317 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11734,948,185 - 34,965,455 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21739,738,270 - 39,740,120 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DEFB128
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3820187,853 - 189,711 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl20187,853 - 189,711 (-)EnsemblGRCh38hg38GRCh38
GRCh3720168,494 - 170,352 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3620116,527 - 118,264 (-)NCBINCBI36Build 36hg18NCBI36
Celera20263,359 - 265,096 (-)NCBICelera
Cytogenetic Map20p13NCBI
HuRef20119,417 - 121,154 (-)NCBIHuRef
CHM1_120168,560 - 170,297 (-)NCBICHM1_1
T2T-CHM13v2.020230,387 - 232,245 (-)NCBIT2T-CHM13v2.0
Defb20
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392152,318,983 - 152,321,645 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2152,318,983 - 152,321,854 (+)EnsemblGRCm39 Ensembl
GRCm382152,477,063 - 152,479,934 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2152,477,063 - 152,479,934 (+)EnsemblGRCm38mm10GRCm38
MGSCv372152,302,799 - 152,305,670 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362152,168,504 - 152,171,375 (+)NCBIMGSCv36mm8
Celera2158,292,563 - 158,295,420 (+)NCBICelera
Cytogenetic Map2H1NCBI
cM Map275.11NCBI
Defb20
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83161,408,395 - 161,411,194 (+)NCBIGRCr8
mRatBN7.23140,948,108 - 140,950,907 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3140,948,154 - 140,950,777 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3144,853,379 - 144,856,066 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03153,437,228 - 153,439,915 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03151,177,235 - 151,179,900 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03147,952,879 - 147,955,502 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3147,952,879 - 147,955,502 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03154,300,300 - 154,301,592 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43142,804,804 - 142,807,427 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera3139,699,738 - 139,702,361 (+)NCBICelera
Cytogenetic Map3q41NCBI
Defb128
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495559764,950 - 66,692 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495559764,950 - 66,692 (-)NCBIChiLan1.0ChiLan1.0
DEFB128
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12420,652,638 - 20,654,574 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2420,652,527 - 20,671,741 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2420,305,580 - 20,307,516 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02421,346,427 - 21,348,363 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2421,346,316 - 21,365,340 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12420,622,473 - 20,624,408 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02420,727,664 - 20,729,599 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02421,158,418 - 21,160,354 (+)NCBIUU_Cfam_GSD_1.0
Defb128
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640169,807,078 - 169,809,261 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493648518,238,442 - 18,240,625 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DEFB128
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl235,309,523 - 35,311,258 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660787,479,022 - 7,481,034 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Defb128
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247411,249,893 - 1,251,715 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in DEFB128
753 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 1
Low 10 4 3 4 2 23 2 2 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000065371   ⟹   ENSSSCP00000057983
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1734,963,674 - 34,965,405 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000097476   ⟹   ENSSSCP00000081165
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1734,963,374 - 34,966,317 (+)Ensembl
RefSeq Acc Id: XM_013983202   ⟹   XP_013838656
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11734,963,534 - 34,965,455 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002340065
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11734,948,185 - 34,965,214 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002340066
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11734,948,185 - 34,965,217 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002340067
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11734,948,777 - 34,965,217 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_013838656   ⟸   XM_013983202
- UniProtKB: A0A287BN95 (UniProtKB/TrEMBL),   A0A4X1SQJ7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000057983   ⟸   ENSSSCT00000065371
RefSeq Acc Id: ENSSSCP00000081165   ⟸   ENSSSCT00000097476
Protein Domains
Beta-defensin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000034080 Ensembl
  ENSSSCG00000055982 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015068848 UniProtKB/TrEMBL
  ENSSSCG00025070722 UniProtKB/TrEMBL
  ENSSSCG00030009513 UniProtKB/TrEMBL
  ENSSSCG00035080326 UniProtKB/TrEMBL
  ENSSSCG00040014270 UniProtKB/TrEMBL
  ENSSSCG00045031499 UniProtKB/TrEMBL
  ENSSSCG00050030682 UniProtKB/TrEMBL
  ENSSSCG00060063483 UniProtKB/TrEMBL
  ENSSSCG00065060090 UniProtKB/TrEMBL
  ENSSSCG00070002858 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000097476 ENTREZGENE
  ENSSSCT00000097476.1 UniProtKB/TrEMBL
  ENSSSCT00015092197.1 UniProtKB/TrEMBL
  ENSSSCT00025097111.1 UniProtKB/TrEMBL
  ENSSSCT00030013017.1 UniProtKB/TrEMBL
  ENSSSCT00035109973.1 UniProtKB/TrEMBL
  ENSSSCT00040019056.1 UniProtKB/TrEMBL
  ENSSSCT00045053685.1 UniProtKB/TrEMBL
  ENSSSCT00050041251.1 UniProtKB/TrEMBL
  ENSSSCT00060086599.1 UniProtKB/TrEMBL
  ENSSSCT00065082284.1 UniProtKB/TrEMBL
  ENSSSCT00070005329.1 UniProtKB/TrEMBL
InterPro Beta_defensin UniProtKB/TrEMBL
KEGG Report ssc:106505985 UniProtKB/TrEMBL
NCBI Gene DEFB128 ENTREZGENE
PANTHER BETA-DEFENSIN UniProtKB/TrEMBL
  BETA-DEFENSIN 123-RELATED UniProtKB/TrEMBL
Pfam Defensin_beta_2 UniProtKB/TrEMBL
UniProt A0A287BN95 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1SQJ7 ENTREZGENE, UniProtKB/TrEMBL