HPF1 (histone PARylation factor 1) - Rat Genome Database

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Gene: HPF1 (histone PARylation factor 1) Sus scrofa
Analyze
Symbol: HPF1
Name: histone PARylation factor 1
RGD ID: 14246672
Description: ENCODES a protein that exhibits chromatin binding (inferred); histone binding (inferred); protein ADP-ribosyltransferase-substrate adaptor activity (inferred); INVOLVED IN DNA damage response (inferred); DNA repair (inferred); DNA repair-dependent chromatin remodeling (inferred); FOUND IN site of DNA damage (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: C14H4orf27; LOC100158040; Uncharacterized protein C4orf27 homolog; UPF0609 protein C4orf27 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1420,014,274 - 20,039,332 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11420,014,254 - 20,037,791 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21421,313,121 - 21,329,267 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
chromatin  (IEA)
chromosome  (IEA)
nucleus  (IBA,IEA)
site of DNA damage  (IEA,ISO)

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
HPF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1420,014,274 - 20,039,332 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11420,014,254 - 20,037,791 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21421,313,121 - 21,329,267 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HPF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384169,729,470 - 169,757,944 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4169,729,470 - 169,757,944 (-)EnsemblGRCh38hg38GRCh38
GRCh374170,650,621 - 170,679,095 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364170,887,194 - 170,915,668 (-)NCBINCBI36Build 36hg18NCBI36
Celera4167,983,601 - 168,012,093 (-)NCBICelera
Cytogenetic Map4q33NCBI
HuRef4166,405,437 - 166,433,881 (-)NCBIHuRef
CHM1_14170,627,188 - 170,655,678 (-)NCBICHM1_1
T2T-CHM13v2.04173,089,586 - 173,118,075 (-)NCBIT2T-CHM13v2.0
Hpf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39861,342,533 - 61,360,615 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl861,343,452 - 61,361,705 (+)EnsemblGRCm39 Ensembl
GRCm38860,890,392 - 60,907,580 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl860,890,418 - 60,908,671 (+)EnsemblGRCm38mm10GRCm38
MGSCv37863,369,248 - 63,386,369 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36863,648,378 - 63,799,724 (+)NCBIMGSCv36mm8
Celera863,457,542 - 63,474,667 (+)NCBICelera
Cytogenetic Map8B3.1NCBI
cM Map830.9NCBI
Hpf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81634,211,971 - 34,230,551 (-)NCBIGRCr8
mRatBN7.21629,203,749 - 29,219,651 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1629,183,256 - 29,219,716 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1632,798,620 - 32,814,503 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01636,232,348 - 36,248,229 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01632,433,869 - 32,449,730 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01632,524,128 - 32,540,233 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1632,519,924 - 32,540,217 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01632,358,968 - 32,375,073 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41632,523,650 - 32,539,537 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11632,523,724 - 32,539,655 (-)NCBI
Celera1629,198,257 - 29,214,140 (-)NCBICelera
Cytogenetic Map16p12NCBI
LOC102030373
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540336,594,269 - 36,622,724 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540336,594,319 - 36,621,020 (+)NCBIChiLan1.0ChiLan1.0
LOC100991754
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23167,506,176 - 167,534,704 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14167,862,061 - 167,890,643 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04161,949,343 - 161,977,887 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14174,021,060 - 174,049,213 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4174,021,060 - 174,049,213 (-)Ensemblpanpan1.1panPan2
HPF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12520,622,781 - 20,645,459 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2520,622,774 - 20,644,822 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2521,257,443 - 21,279,874 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02520,798,645 - 20,821,091 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2520,798,649 - 20,820,457 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12520,682,932 - 20,705,345 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02520,618,769 - 20,641,207 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02520,718,372 - 20,740,811 (-)NCBIUU_Cfam_GSD_1.0
LOC101970824
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494321,349,641 - 21,371,280 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365161,763,935 - 1,785,538 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC103236518
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17115,934,687 - 115,966,404 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7115,934,692 - 115,966,369 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603795,880,912 - 95,912,880 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101705414
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247691,239,455 - 1,261,901 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247691,239,399 - 1,261,770 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in HPF1
652 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000010647   ⟹   ENSSSCP00000010370
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1420,014,347 - 20,034,755 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000037055   ⟹   ENSSSCP00000045446
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1420,013,977 - 20,039,356 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000050715   ⟹   ENSSSCP00000057448
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1420,014,274 - 20,039,332 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000056532   ⟹   ENSSSCP00000054006
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1420,017,285 - 20,039,332 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000076486   ⟹   ENSSSCP00000068426
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1420,017,285 - 20,039,356 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000088954   ⟹   ENSSSCP00000063357
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1420,016,672 - 20,039,332 (+)Ensembl
RefSeq Acc Id: XM_021073226   ⟹   XP_020928885
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11420,014,254 - 20,037,791 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021073227   ⟹   XP_020928886
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11420,014,254 - 20,037,089 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021073228   ⟹   XP_020928887
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11420,016,665 - 20,036,017 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021073229   ⟹   XP_020928888
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11420,014,254 - 20,036,677 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021073230   ⟹   XP_020928889
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11420,014,254 - 20,037,089 (+)NCBI
Sequence:
RefSeq Acc Id: XP_020928885   ⟸   XM_021073226
- Peptide Label: isoform X1
- UniProtKB: A0A287BM02 (UniProtKB/TrEMBL),   A0A4X1V5N3 (UniProtKB/TrEMBL),   A0A8D0JIF9 (UniProtKB/TrEMBL),   A0A8D1AC80 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020928886   ⟸   XM_021073227
- Peptide Label: isoform X2
- UniProtKB: A0A480UQN7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020928889   ⟸   XM_021073230
- Peptide Label: isoform X5
- UniProtKB: A0A4X1V5L8 (UniProtKB/TrEMBL),   A0A8D0JME3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020928888   ⟸   XM_021073229
- Peptide Label: isoform X4
- UniProtKB: A0A8D1EV47 (UniProtKB/TrEMBL),   A0A480PFI2 (UniProtKB/TrEMBL),   A0A8D1ACY8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020928887   ⟸   XM_021073228
- Peptide Label: isoform X3
- UniProtKB: A0A4X1V538 (UniProtKB/TrEMBL),   A0A8D0JPK6 (UniProtKB/TrEMBL),   A0A8D1CXD6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000063357   ⟸   ENSSSCT00000088954
Ensembl Acc Id: ENSSSCP00000010370   ⟸   ENSSSCT00000010647
Ensembl Acc Id: ENSSSCP00000057448   ⟸   ENSSSCT00000050715
Ensembl Acc Id: ENSSSCP00000068426   ⟸   ENSSSCT00000076486
Ensembl Acc Id: ENSSSCP00000045446   ⟸   ENSSSCT00000037055
Ensembl Acc Id: ENSSSCP00000054006   ⟸   ENSSSCT00000056532


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000009711 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005028186 UniProtKB/TrEMBL
  ENSSSCG00015036054 UniProtKB/TrEMBL
  ENSSSCG00025026390 UniProtKB/TrEMBL
  ENSSSCG00030054954 UniProtKB/TrEMBL
  ENSSSCG00035052220 UniProtKB/TrEMBL
  ENSSSCG00040046935 UniProtKB/TrEMBL
  ENSSSCG00045015874 UniProtKB/TrEMBL
  ENSSSCG00050021730 UniProtKB/TrEMBL
  ENSSSCG00055030326 UniProtKB/TrEMBL
  ENSSSCG00060063712 UniProtKB/TrEMBL
  ENSSSCG00065060426 UniProtKB/TrEMBL
  ENSSSCG00070021917 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000050715 ENTREZGENE
  ENSSSCT00000050715.3 UniProtKB/TrEMBL
  ENSSSCT00000056532.3 UniProtKB/TrEMBL
  ENSSSCT00000088954.2 UniProtKB/TrEMBL
  ENSSSCT00005045211.1 UniProtKB/TrEMBL
  ENSSSCT00005045261.1 UniProtKB/TrEMBL
  ENSSSCT00005045330.1 UniProtKB/TrEMBL
  ENSSSCT00015049672.1 UniProtKB/TrEMBL
  ENSSSCT00015049775.1 UniProtKB/TrEMBL
  ENSSSCT00015050102.1 UniProtKB/TrEMBL
  ENSSSCT00025035876.1 UniProtKB/TrEMBL
  ENSSSCT00025036198.1 UniProtKB/TrEMBL
  ENSSSCT00025036270.1 UniProtKB/TrEMBL
  ENSSSCT00030076699.1 UniProtKB/TrEMBL
  ENSSSCT00030076711.1 UniProtKB/TrEMBL
  ENSSSCT00030076744.1 UniProtKB/TrEMBL
  ENSSSCT00035069644.1 UniProtKB/TrEMBL
  ENSSSCT00035069648.1 UniProtKB/TrEMBL
  ENSSSCT00035069657.1 UniProtKB/TrEMBL
  ENSSSCT00040063642.1 UniProtKB/TrEMBL
  ENSSSCT00040063716.1 UniProtKB/TrEMBL
  ENSSSCT00040063819.1 UniProtKB/TrEMBL
  ENSSSCT00045027308.1 UniProtKB/TrEMBL
  ENSSSCT00045027346.1 UniProtKB/TrEMBL
  ENSSSCT00045027424.1 UniProtKB/TrEMBL
  ENSSSCT00050029558.1 UniProtKB/TrEMBL
  ENSSSCT00050029573.1 UniProtKB/TrEMBL
  ENSSSCT00050029611.1 UniProtKB/TrEMBL
  ENSSSCT00055060430.1 UniProtKB/TrEMBL
  ENSSSCT00055060433.1 UniProtKB/TrEMBL
  ENSSSCT00055060445.1 UniProtKB/TrEMBL
  ENSSSCT00060087288.1 UniProtKB/TrEMBL
  ENSSSCT00060087311.1 UniProtKB/TrEMBL
  ENSSSCT00060087351.1 UniProtKB/TrEMBL
  ENSSSCT00065082870.1 UniProtKB/TrEMBL
  ENSSSCT00065082876.1 UniProtKB/TrEMBL
  ENSSSCT00065082888.1 UniProtKB/TrEMBL
  ENSSSCT00070043585.1 UniProtKB/TrEMBL
  ENSSSCT00070043602.1 UniProtKB/TrEMBL
  ENSSSCT00070043605.1 UniProtKB/TrEMBL
InterPro HPF1 UniProtKB/TrEMBL
NCBI Gene LOC100158040 ENTREZGENE
PANTHER HISTONE PARYLATION FACTOR 1 UniProtKB/TrEMBL
  PTHR13386 UniProtKB/TrEMBL
Pfam DUF2228 UniProtKB/TrEMBL
UniProt A0A287BBV0_PIG UniProtKB/TrEMBL
  A0A287BM02 ENTREZGENE, UniProtKB/TrEMBL
  A0A480PFI2 ENTREZGENE, UniProtKB/TrEMBL
  A0A480UQN7 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1V538 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1V5L8 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1V5N3 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2QF60_PIG UniProtKB/TrEMBL
  A0A8D0JIF9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0JME3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0JPK6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1AC80 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1ACY8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1CXD6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1EV47 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A287ANE5 UniProtKB/TrEMBL
  A0A5G2QU10 UniProtKB/TrEMBL
VGNC ID VGNC:107399 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-06-07 HPF1  histone PARylation factor 1  LOC100158040  histone PARylation factor 1  Symbol and/or name change 19259463 PROVISIONAL