EVC (EvC ciliary complex subunit 1) - Rat Genome Database

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Gene: EVC (EvC ciliary complex subunit 1) Sus scrofa
Analyze
Symbol: EVC
Name: EvC ciliary complex subunit 1
RGD ID: 14243740
Description: INVOLVED IN cartilage development (ortholog); ASSOCIATED WITH Ellis-Van Creveld syndrome (ortholog); genetic disease (ortholog); nephronophthisis (ortholog); FOUND IN cell projection (inferred); ciliary basal body (inferred); ciliary membrane (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ellis-van Creveld syndrome protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl84,810,093 - 4,891,165 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.184,808,622 - 4,891,236 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.282,327,527 - 2,352,194 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
EVC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl84,810,093 - 4,891,165 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.184,808,622 - 4,891,236 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.282,327,527 - 2,352,194 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EVC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3845,711,201 - 5,829,057 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl45,711,201 - 5,814,305 (+)EnsemblGRCh38hg38GRCh38
GRCh3745,712,928 - 5,816,032 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3645,763,825 - 5,866,932 (+)NCBINCBI36Build 36hg18NCBI36
Build 3445,830,995 - 5,934,103NCBI
Celera45,610,660 - 5,713,978 (+)NCBICelera
Cytogenetic Map4p16.2NCBI
HuRef45,648,399 - 5,751,953 (+)NCBIHuRef
CHM1_145,710,930 - 5,813,984 (+)NCBICHM1_1
T2T-CHM13v2.045,682,855 - 5,800,650 (+)NCBIT2T-CHM13v2.0
Evc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39537,446,314 - 37,495,489 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl537,446,442 - 37,494,238 (-)EnsemblGRCm39 Ensembl
GRCm38537,288,970 - 37,336,947 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl537,289,098 - 37,336,894 (-)EnsemblGRCm38mm10GRCm38
MGSCv37537,690,410 - 37,728,120 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36537,587,422 - 37,625,110 (-)NCBIMGSCv36mm8
Celera534,748,894 - 34,787,541 (-)NCBICelera
Cytogenetic Map5B3NCBI
cM Map520.06NCBI
Evc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81477,680,901 - 77,722,608 (+)NCBIGRCr8
mRatBN7.21473,456,181 - 73,498,955 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1473,456,222 - 73,498,099 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1477,901,822 - 77,941,920 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01479,142,670 - 79,182,768 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01475,587,290 - 75,627,338 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01478,213,601 - 78,253,266 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1478,213,635 - 78,253,266 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01478,187,667 - 78,227,302 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41479,020,120 - 79,060,046 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11479,034,502 - 79,040,894 (+)NCBI
Celera1472,408,984 - 72,448,907 (+)NCBICelera
Cytogenetic Map14q21NCBI
Evc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555144,279,073 - 4,331,131 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555144,279,603 - 4,330,897 (-)NCBIChiLan1.0ChiLan1.0
EVC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v235,975,357 - 6,098,852 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan145,908,343 - 6,023,859 (+)NCBINHGRI_mPanPan1
PanPan1.145,790,437 - 5,892,283 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl45,789,316 - 5,894,265 (+)Ensemblpanpan1.1panPan2
EVC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1370,937,957 - 71,007,431 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl370,937,926 - 71,016,115 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha373,488,645 - 73,558,112 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0371,699,331 - 71,768,497 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl371,699,331 - 71,768,497 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1370,969,854 - 71,038,897 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0371,130,786 - 71,200,049 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0371,508,152 - 71,577,452 (+)NCBIUU_Cfam_GSD_1.0
Evc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528564,239,100 - 64,295,647 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647717,937,677 - 17,993,727 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647717,940,792 - 17,992,996 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EVC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12741,853,475 - 41,944,584 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2741,861,918 - 41,944,333 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604788,647,349 - 88,739,173 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Evc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475522,437,167 - 22,478,591 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475522,432,174 - 22,478,595 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in EVC
5126 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 2
Low 8 4 3 4 2 23 3
Below cutoff 2 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000042764   ⟹   ENSSSCP00000049939
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl84,810,093 - 4,891,165 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000058346   ⟹   ENSSSCP00000040646
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl84,809,155 - 4,891,257 (-)Ensembl
RefSeq Acc Id: XM_021100988   ⟹   XP_020956647
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.184,808,622 - 4,891,230 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021100989   ⟹   XP_020956648
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.184,808,622 - 4,891,231 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021100990   ⟹   XP_020956649
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.184,808,622 - 4,891,232 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021100991   ⟹   XP_020956650
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.184,812,210 - 4,891,233 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021100992   ⟹   XP_020956651
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.184,842,374 - 4,891,236 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020956649   ⟸   XM_021100990
- Peptide Label: isoform X3
- UniProtKB: A0A287A9Z9 (UniProtKB/TrEMBL),   A0A8D1P3A6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020956648   ⟸   XM_021100989
- Peptide Label: isoform X2
- UniProtKB: A0A8D1PB40 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020956647   ⟸   XM_021100988
- Peptide Label: isoform X1
- UniProtKB: A0A480R021 (UniProtKB/TrEMBL),   A0A8D1PB40 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020956650   ⟸   XM_021100991
- Peptide Label: isoform X4
- UniProtKB: A0A8D1PB40 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020956651   ⟸   XM_021100992
- Peptide Label: isoform X5
- UniProtKB: A0A480LPL1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000040646   ⟸   ENSSSCT00000058346
RefSeq Acc Id: ENSSSCP00000049939   ⟸   ENSSSCT00000042764


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000032637 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00055000733 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000042764 ENTREZGENE
  ENSSSCT00000042764.3 UniProtKB/TrEMBL
  ENSSSCT00055001271.1 UniProtKB/TrEMBL
  ENSSSCT00055001328.1 UniProtKB/TrEMBL
InterPro Limbin/Ellis-van_Creveld UniProtKB/TrEMBL
NCBI Gene EVC ENTREZGENE
PANTHER PTHR16795 UniProtKB/TrEMBL
  PTHR16795:SF13 UniProtKB/TrEMBL
UniProt A0A287A9Z9 ENTREZGENE, UniProtKB/TrEMBL
  A0A287B0J8_PIG UniProtKB/TrEMBL
  A0A480LPL1 ENTREZGENE, UniProtKB/TrEMBL
  A0A480R021 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1P3A6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1PB40 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:87818 ENTREZGENE